Page last updated: 2024-08-25

avarol and avarone

avarol has been researched along with avarone in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19905 (23.81)18.7374
1990's5 (23.81)18.2507
2000's6 (28.57)29.6817
2010's3 (14.29)24.3611
2020's2 (9.52)2.80

Authors

AuthorsStudies
Broughton, HB; Castro, MA; Chamorro, P; García-Grávalos, MD; Gordaliza, M; Mahiques, MM; Miguel Del Corral, JM; Molinari, A; San Feliciano, A1
De Rosa, S; Iodice, C; Pejin, B; Tommonaro, G1
Guo, YW; Li, Y; Shen, X; Zhang, Y1
Bozić, T; Gasić, MJ; Juranić, Z; Kljajić, Z; Novaković, I; Sladić, D; Stanojković, T; Tufegdzić, S1
Fritz, G; Proksch, P; van Stuijvenberg, J1
Belisario, MA; De Rosa, S; Maturo, M; Pecce, R; Villani, GR1
Hizi, A; Loya, S1
Arena, AR; Belisario, MA; De Giulio, A; De Rosa, S; Pecce, R; Strazzullo, G1
Müller, WE; Sarin, PS; Sun, D; Thornton, A1
Diehl-Seifert, B; Eich, E; Kljajić, Z; Müller, WE; Sachsse, W; Schröder, HC; Sobel, C; Zahn, RK1
Bernd, A; Eich, E; Gasić, MJ; Heidemann, D; Kurelec, B; Maidhof, A; Müller, WE; Schröder, HC; Seibert, G; Zahn, RK1
Dogović, N; Gasić, MJ; Müller, WE; Raether, W; Seibert, G; Zahn, RK1
Britvić, S; Gasić, MJ; Kurelec, B; Lucić, D; Müller, WE; Zahn, RK1
Alcaraz, MJ; Bustos, G; De Rosa, S; Ferrándiz, ML; Payá, M; Sanz, MJ1
Avagnale, G; Belisario, MA; De Caterina, M; De Rosa, S; Maturo, M; Scopacasa, F1
Kim, SH; Ling, T; Poupon, E; Rueden, EJ; Theodorakis, EA1
Chakraborty, R; Kuo, YH; Lu, CH; Shen, YC1
Abe, H; Ishikawa, M; Kanno, S; Katoh, T; Oguchi, T; Sakurai, J; Watanabe, K1
Glumac, M; Jakimov, D; Kojic, V; Pejin, B; Tommonaro, G1
Kolarević, S; Kostić, J; Kračun-Kolarević, M; Martinović, R; Milovanović, D; Novaković, I; Sladić, D; Sunjog, K; Vuković-Gačić, B; Đorđević, J1
Aiello, A; Avunduk, S; Basilico, N; Casertano, M; Fattorusso, C; Gimmelli, R; Guidi, A; Imperatore, C; Luciano, P; Menna, M; Parapini, S; Persico, M; Ruberti, G; Saccoccia, F1

Other Studies

21 other study(ies) available for avarol and avarone

ArticleYear
New selective cytotoxic diterpenylquinones and diterpenylhydroquinones.
    Journal of medicinal chemistry, 2001, Apr-12, Volume: 44, Issue:8

    Topics: Animals; Antineoplastic Agents; Diterpenes; Drug Screening Assays, Antitumor; Humans; Mice; Models, Molecular; Quinones; Structure-Activity Relationship; Tumor Cells, Cultured

2001
Synthesis and biological activities of thio-avarol derivatives.
    Journal of natural products, 2008, Volume: 71, Issue:11

    Topics: Animals; Anti-Infective Agents; Artemia; Cholinesterase Inhibitors; Dysidea; Free Radical Scavengers; Microbial Sensitivity Tests; Sesquiterpenes; Structure-Activity Relationship; Sulfur Compounds

2008
A novel sesquiterpene quinone from Hainan sponge Dysidea villosa.
    Bioorganic & medicinal chemistry letters, 2009, Jan-15, Volume: 19, Issue:2

    Topics: Animals; Drug Evaluation, Preclinical; HeLa Cells; Humans; Magnetic Resonance Spectroscopy; Porifera; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Quinones; Sesquiterpenes

2009
Synthesis and biological activity of derivatives of the marine quinone avarone.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Anti-HIV Agents; Antineoplastic Agents; Artemia; Cell Line, Tumor; Cyclohexenes; Dysidea; Female; HeLa Cells; HIV-1; Humans; Inhibitory Concentration 50; Molecular Structure; Quinones; Sesquiterpenes; Stereoisomerism; Uterine Cervical Neoplasms

2010
Targeting the DNA damage response (DDR) by natural compounds.
    Bioorganic & medicinal chemistry, 2020, 02-15, Volume: 28, Issue:4

    Topics: Antineoplastic Agents; Biological Products; Cell Proliferation; Cell Survival; Cisplatin; DNA Damage; DNA, Neoplasm; Dose-Response Relationship, Drug; Doxorubicin; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Structure-Activity Relationship; Tumor Cells, Cultured

2020
Effect of avarol and avarone on in vitro-induced microsomal lipid peroxidation.
    Toxicology, 1992, Volume: 72, Issue:2

    Topics: Animals; Antineoplastic Agents; Chromatography, High Pressure Liquid; Cyclohexenes; Electron Transport; Lipid Peroxidation; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Rats; Rats, Inbred Strains; Sesquiterpenes

1992
The inhibition of human immunodeficiency virus type 1 reverse transcriptase by avarol and avarone derivatives.
    FEBS letters, 1990, Aug-20, Volume: 269, Issue:1

    Topics: Animals; Cyclohexenes; Deoxyguanine Nucleotides; Endoribonucleases; HIV-1; Kinetics; Porifera; Reverse Transcriptase Inhibitors; Ribonuclease H; Sesquiterpenes; Structure-Activity Relationship

1990
Effect of avarol, avarone and nine of their natural and synthetic derivatives on microsomal drug-metabolizing enzymes.
    Toxicology letters, 1991, Volume: 57, Issue:2

    Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Antineoplastic Agents; Cyclohexenes; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Male; Methylcholanthrene; Microsomes, Liver; Mutagenicity Tests; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains; Sesquiterpenes

1991
Inhibition of replication of the etiologic agent of acquired immune deficiency syndrome (human T-lymphotropic retrovirus/lymphadenopathy-associated virus) by avarol and avarone.
    Journal of the National Cancer Institute, 1987, Volume: 78, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Cell Line; Cyclohexenes; Cytopathogenic Effect, Viral; HIV; Humans; Reverse Transcriptase Inhibitors; Sesquiterpenes; Virus Replication

1987
Biphasic and differential effects of the cytostatic agents avarone and avarol on DNA metabolism of human and murine T and B lymphocytes.
    European journal of cancer & clinical oncology, 1986, Volume: 22, Issue:4

    Topics: Animals; B-Lymphocytes; Cyclohexenes; DNA; Humans; Lymphocyte Activation; Male; Mice; Mitogens; Mitotic Index; Sesquiterpenes; Spleen; T-Lymphocytes

1986
Potent antileukemic activity of the novel cytostatic agent avarone and its analogues in vitro and in vivo.
    Cancer research, 1985, Volume: 45, Issue:10

    Topics: Animals; Antineoplastic Agents; Cell Line; Cyclohexenes; Humans; Lethal Dose 50; Leukemia; Male; Mice; Mutagens; Sesquiterpenes

1985
Antibacterial and antifungal activity of Avarone and Avarol.
    Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology, 1985, Volume: 260, Issue:3

    Topics: Bacteria; Cyclohexenes; Dose-Response Relationship, Drug; Fungi; Quinones; Sesquiterpenes

1985
Antimutagenic activity of the novel antileukemic agents, avarone and avarol.
    Mutation research, 1985, Volume: 144, Issue:2

    Topics: Animals; Antineoplastic Agents; Benzopyrene Hydroxylase; Biotransformation; Carps; Cyclohexenes; Microsomes, Liver; Mutagenicity Tests; Mutagens; Salmonella typhimurium; Sesquiterpenes

1985
Avarol and avarone, two new anti-inflammatory agents of marine origin.
    European journal of pharmacology, 1994, Feb-21, Volume: 253, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Carrageenan; Cyclohexenes; Edema; Indomethacin; Inflammation; Leukocytes; Male; Mice; Peritoneum; Phospholipases A; Phospholipases A2; Rats; Sesquiterpenes; Superoxides; Tetradecanoylphorbol Acetate

1994
In vitro effect of avarone and avarol, a quinone/hydroquinone couple of marine origin, on platelet aggregation.
    Pharmacology & toxicology, 1996, Volume: 79, Issue:6

    Topics: Adenosine Diphosphate; Antineoplastic Agents; Arachidonic Acid; Blood Platelets; Cyclohexenes; Humans; Platelet Aggregation Inhibitors; Sesquiterpenes; Thromboxane B2

1996
Unified synthesis of quinone sesquiterpenes based on a radical decarboxylation and quinone addition reaction.
    Journal of the American Chemical Society, 2002, Oct-16, Volume: 124, Issue:41

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Antiviral Agents; Cyclohexenes; Quinones; Sesquiterpenes; Substrate Specificity

2002
Isolation of sesquiterpenoids from sponge Dysidea avara and chemical modification of avarol as potential antitumor agents.
    Natural product research, 2003, Volume: 17, Issue:2

    Topics: Acylation; Animals; Antineoplastic Agents; Cyclohexenes; Humans; Inhibitory Concentration 50; KB Cells; Phytotherapy; Porifera; Sesquiterpenes; Tumor Cells, Cultured

2003
Highly efficient total synthesis of the marine natural products (+)-avarone, (+)-avarol, (-)-neoavarone, (-)-neoavarol and (+)-aureol.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2008, Volume: 14, Issue:3

    Topics: Biological Factors; Cyclohexenes; Molecular Conformation; Sesquiterpenes; Stereoisomerism

2008
The redox couple avarol/avarone in the fight with malignant gliomas: the case study of U-251 MG cells.
    Natural product research, 2018, Volume: 32, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Comet Assay; Cyclohexenes; Dacarbazine; DNA Damage; Doxorubicin; Fibroblasts; Glioma; Humans; Oxidation-Reduction; Sesquiterpenes; Temozolomide

2018
Evaluation of genotoxic potential of avarol, avarone, and its methoxy and methylamino derivatives in prokaryotic and eukaryotic test models.
    Drug and chemical toxicology, 2019, Volume: 42, Issue:2

    Topics: A549 Cells; Cell Line, Tumor; Comet Assay; Cyclohexenes; DNA Damage; Humans; Male; Mutagens; Salmonella typhimurium; Sesquiterpenes; Toxicity Tests

2019
Investigating the Antiparasitic Potential of the Marine Sesquiterpene Avarone, Its Reduced form Avarol, and the Novel Semisynthetic Thiazinoquinone Analogue Thiazoavarone.
    Marine drugs, 2020, Feb-14, Volume: 18, Issue:2

    Topics: Animals; Antiparasitic Agents; Cyclohexenes; Dysidea; Leishmania; Leishmania infantum; Leishmania tropica; Plasmodium falciparum; Quinones; Schistosoma mansoni; Sesquiterpenes; Thiazines

2020