avapro and enalapril

avapro has been researched along with enalapril in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (28.57)18.2507
2000's16 (45.71)29.6817
2010's9 (25.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abbenante, G; Fairlie, DP; Leung, D1
Andricopulo, AD; Moda, TL; Montanari, CA1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Barton, P; Luker, T; Wenlock, MC1
Giacomini, KM; Huang, Y; Khuri, N; Kido, Y; Kosaka, A; Morrissey, KM; Sali, A; Wittwer, MB; Zhang, X; Zur, AA1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Canals, F; Cazaubon, C; Galindo, G; Lacour, C; Nisato, D; Segondy, D1
Velasquez, MT1
Brenner, BM; Mackenzie, HS; Ots, M; Provoost, AP; Rennke, HG; Troy, JL; Ziai, F1
Flack, JM; Krieger, EM; Larochelle, P; Marbury, TC; Reeves, RA; Sareli, P1
Armagnac, C; Bouroudian, M; Brunner, HR; Burnier, M; Decosterd, L; Nussberger, J; Pechère-Bertschi, A; Sissmann, J1
Kassler-Taub, K; Kerwin, L; Mimran, A; Nys, M; Osbakken, M; Owens, D; Ruilope, L1
Azzollini, N; Mister, M; Perico, N; Remuzzi, A; Remuzzi, G; Ruggenenti, P; Sangalli, F1
Brown, MJ1
Moriggi, M; Perico, N; Remuzzi, A; Remuzzi, G; Ruggenenti, P; Sangalli, F; Vendramin, G1
Bertrand, M; Brabant, SM; Coriat, P; Eyraud, D1
Chang, MS; Chao, CT; Chen, CH; Chen, YT; Chiang, AH; Chiou, KR; Ding, PY; Huang, JL; Liu, CP; Ting, CT; Tseng, CJ1
Li, J; Wang, H; Yu, L; Zhang, J; Zhou, A1
Lacourcière, Y1
Arruda, JA; Dunea, G; Garber, SL; Mirochnik, Y; Slobodskoy, L1
Casellas, D; Herizi, A; Jover, B; Mimran, A1
Kurtzman, NA1
Aguilera, MT; Calvo, C; Coca, A; de la Sierra, A; García-Puig, J; Gil-Extremera, B; Marín, R; Martín-Hidalgo, A1
Rapi, J1
Andersen, S; Jacobsen, P; Jensen, BR; Parving, HH; Rossing, K1
Briand, D; Canals, F; Galindo, G; Herbert, JM; Hogie, M; Lacour, C; Nisato, D; Roccon, A; Roque, C; Segondy, D1
Böger, RH; Bünte, C; Drexler, H; Hoeper, K; Schieffer, B; Schwedhelm, E; Witte, J1
Blanchet, M; Curnier, D; De Champlain, J; Ducharme, A; Lamoureux, MC; Racine, N; Sheppard, R; Sirois, P; Tardif, JC; White, M1
Mailloux, D; McCabe, J; Stork, C; Su, M1
Bhatt, DL; Drexler, H; Gallo, R; Montalescot, G; Pearson, T; Thoenes, M1
Li, G; Li, J; Liu, E; Xu, Z; Yang, S; Yang, W1
Alvarez-Ude, F; Fernández-Reyes, MJ; Heras, M; Pardo, J; Saiz, A; Sánchez, R1
Circelli, M; Cremonesi, G; Fogari, R; Mugellini, A1
Jansook, P; Loftsson, T; Muankaew, C; Stefánsson, E1
Hamaoka, K; Morimoto, M; Nishida, M; Ohno, K1

Reviews

6 review(s) available for avapro and enalapril

ArticleYear
Protease inhibitors: current status and future prospects.
    Journal of medicinal chemistry, 2000, Feb-10, Volume: 43, Issue:3

    Topics: Animals; Aspartic Acid Endopeptidases; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Humans; Metalloendopeptidases; Models, Molecular; Protease Inhibitors; Serine Endopeptidases; Serine Proteinase Inhibitors

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Angiotensin II receptor blockers. A new class of antihypertensive drugs.
    Archives of family medicine, 1996, Volume: 5, Issue:6

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzothiadiazines; Biphenyl Compounds; Blood Pressure; Clinical Trials as Topic; Diuretics; Enalapril; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Multicenter Studies as Topic; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Sodium Chloride Symporter Inhibitors; Tetrazoles

1996
Irbesartan treatment in hypertension.
    Hospital medicine (London, England : 1998), 1998, Volume: 59, Issue:10

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Biphenyl Compounds; Enalapril; Humans; Hypertension; Irbesartan; Losartan; Renin-Angiotensin System; Tetrazoles

1998
[Irbesartan: a new possibility in the treatment of hypertension].
    Orvosi hetilap, 2002, May-26, Volume: 143, Issue:21

    Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Atenolol; Benzimidazoles; Benzoates; Biological Availability; Biphenyl Compounds; Controlled Clinical Trials as Topic; Drug Administration Schedule; Enalapril; Half-Life; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan

2002
Combination delapril/manidipine as antihypertensive therapy in high-risk patients.
    Clinical drug investigation, 2011, Volume: 31, Issue:7

    Topics: Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Clinical Trials as Topic; Diabetes Complications; Dihydropyridines; Drug Combinations; Enalapril; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Indans; Irbesartan; Losartan; Nitrobenzenes; Obesity; Olmesartan Medoxomil; Piperazines; Ramipril; Tetrazoles; Valine; Valsartan

2011

Trials

12 trial(s) available for avapro and enalapril

ArticleYear
Effects and tolerability of irbesartan versus enalapril in patients with severe hypertension. Irbesartan Multicenter Investigators.
    The American journal of cardiology, 1997, Dec-15, Volume: 80, Issue:12

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Irbesartan; Male; Middle Aged; Single-Blind Method; Tetrazoles

1997
Renal response to the angiotensin II receptor subtype 1 antagonist irbesartan versus enalapril in hypertensive patients.
    Journal of hypertension, 1998, Volume: 16, Issue:3

    Topics: Adult; Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Enalapril; Female; Humans; Hypertension; Irbesartan; Male; Middle Aged; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Circulation; Renin-Angiotensin System; Tetrazoles; Time Factors; Vasodilation

1998
A randomised, double-blind comparison of the angiotensin II receptor antagonist, irbesartan, with the full dose range of enalapril for the treatment of mild-to-moderate hypertension.
    Journal of human hypertension, 1998, Volume: 12, Issue:3

    Topics: Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Diastole; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Irbesartan; Male; Middle Aged; Tetrazoles

1998
The antiproteinuric effect of angiotensin antagonism in human IgA nephropathy is potentiated by indomethacin.
    Journal of the American Society of Nephrology : JASN, 1998, Volume: 9, Issue:12

    Topics: Adult; Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Enalapril; Female; Glomerulonephritis, IGA; Humans; Hypertension, Renal; Indomethacin; Irbesartan; Kidney Function Tests; Male; Middle Aged; Proteinuria; Renal Circulation; Tetrazoles; Treatment Outcome

1998
ACE inhibition and ANG II receptor blockade improve glomerular size-selectivity in IgA nephropathy.
    The American journal of physiology, 1999, Volume: 276, Issue:3

    Topics: Adult; Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Compounds; Blood Pressure; Dextrans; Enalapril; Female; Glomerulonephritis, IGA; Humans; Irbesartan; Kidney; Kidney Glomerulus; Male; Middle Aged; Molecular Weight; Single-Blind Method; Tetrazoles

1999
Randomized, double-blind comparison of irbesartan and enalapril for treatment of mild to moderate hypertension.
    Zhonghua yi xue za zhi = Chinese medical journal; Free China ed, 2000, Volume: 63, Issue:5

    Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Irbesartan; Male; Middle Aged; Tetrazoles

2000
A multicenter, randomized, double-blind study of the antihypertensive efficacy and tolerability of irbesartan in patients aged > or = 65 years with mild to moderate hypertension.
    Clinical therapeutics, 2000, Volume: 22, Issue:10

    Topics: Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Irbesartan; Male; Tetrazoles

2000
A multicenter, randomized, double-blind comparison of the efficacy and safety of irbesartan and enalapril in adults with mild to moderate essential hypertension, as assessed by ambulatory blood pressure monitoring: the MAPAVEL Study (Monitorización Ambula
    Clinical therapeutics, 2002, Volume: 24, Issue:1

    Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Irbesartan; Male; Middle Aged; Spain; Tetrazoles; Treatment Outcome

2002
Dual blockade of the renin-angiotensin system versus maximal recommended dose of ACE inhibition in diabetic nephropathy.
    Kidney international, 2003, Volume: 63, Issue:5

    Topics: Adult; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Enalapril; Female; Humans; Irbesartan; Male; Middle Aged; Renin-Angiotensin System; Tetrazoles

2003
Comparative effects of AT1-antagonism and angiotensin-converting enzyme inhibition on markers of inflammation and platelet aggregation in patients with coronary artery disease.
    Journal of the American College of Cardiology, 2004, Jul-21, Volume: 44, Issue:2

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Biomarkers; Biphenyl Compounds; C-Reactive Protein; Coronary Artery Disease; Dinoprostone; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Inflammation; Interleukin-10; Interleukin-6; Irbesartan; Male; Matrix Metalloproteinase 9; Middle Aged; Platelet Aggregation; Tetrazoles; Thromboxane A2

2004
Effects of angiotensin-converting enzyme inhibitor plus irbesartan on maximal and submaximal exercise capacity and neurohumoral activation in patients with congestive heart failure.
    American heart journal, 2005, Volume: 149, Issue:5

    Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Compounds; Double-Blind Method; Drug Therapy, Combination; Enalapril; Exercise Tolerance; Female; Heart Failure; Humans; Irbesartan; Lactic Acid; Male; Middle Aged; Norepinephrine; Prospective Studies; Rest; Tetrazoles

2005
Effect of irbesartan and enalapril in non-ST elevation acute coronary syndrome: results of the randomized, double-blind ARCHIPELAGO study.
    European heart journal, 2009, Volume: 30, Issue:22

    Topics: Acute Coronary Syndrome; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Biomarkers; Biphenyl Compounds; Blood Pressure; C-Reactive Protein; Double-Blind Method; Enalapril; Female; Humans; Irbesartan; Male; Middle Aged; Tetrazoles; Treatment Outcome

2009

Other Studies

17 other study(ies) available for avapro and enalapril

ArticleYear
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Lipophilicity of acidic compounds: impact of ion pair partitioning on drug design.
    Bioorganic & medicinal chemistry letters, 2011, Jun-15, Volume: 21, Issue:12

    Topics: Acids; Albumins; Drug Design; Humans; Hydrogen-Ion Concentration; Lipids; Molecular Structure; Pharmaceutical Preparations; Protein Binding

2011
Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling.
    Journal of medicinal chemistry, 2013, Feb-14, Volume: 56, Issue:3

    Topics: Computer Simulation; Fluorescent Dyes; Organic Cation Transport Proteins; Prescription Drugs

2013
Efficacy of SR 47436 (BMS-186295), a non-peptide angiotensin AT1 receptor antagonist in hypertensive rat models.
    European journal of pharmacology, 1994, Nov-03, Volume: 264, Issue:3

    Topics: Administration, Oral; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Desoxycorticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Enalapril; Hypertension, Renal; Imidazoles; Injections, Intravenous; Irbesartan; Losartan; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Tachycardia; Tetrazoles

1994
The angiotensin receptor antagonist, irbesartan, reduces renal injury in experimental chronic renal failure.
    Kidney international. Supplement, 1996, Volume: 57

    Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Enalapril; Irbesartan; Kidney Failure, Chronic; Kidney Glomerulus; Nephrectomy; Proteinuria; Rats; Rats, Inbred SHR; Tetrazoles

1996
Refractory hypotension after induction of anesthesia in a patient chronically treated with angiotensin receptor antagonists.
    Anesthesia and analgesia, 1999, Volume: 89, Issue:4

    Topics: Adrenergic Agents; Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Enalapril; Endarterectomy, Carotid; Ephedrine; Humans; Hypotension; Irbesartan; Lypressin; Male; Phenylephrine; Terlipressin; Tetrazoles; Vasoconstrictor Agents

1999
Renal protective effects of blocking the intrarenal renin-angiotensin system: angiotensin II type I receptor antagonist compared with angiotensin-converting enzyme inhibitor.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2000, Volume: 23, Issue:4

    Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Enalapril; Fibrosis; Irbesartan; Kidney; Male; Nephrotic Syndrome; Proteinuria; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Tetrazoles

2000
Differential effects of enalapril and irbesartan in experimental papillary necrosis.
    Kidney & blood pressure research, 2001, Volume: 24, Issue:1

    Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Enalapril; Irbesartan; Kidney Papillary Necrosis; Male; Rats; Rats, Sprague-Dawley; Tetrazoles

2001
Influence of irbesartan and enalapril on changes of renal function associated with the established phase of l-NAME hypertension.
    Journal of hypertension, 2001, Volume: 19, Issue:11

    Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Blood Vessels; Cardiovascular System; Drug Combinations; Enalapril; Enzyme Inhibitors; Hemodynamics; Hypertension; Irbesartan; Kidney; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renal Circulation; Tail; Tetrazoles

2001
Drug companies should not have the final say in the design of clinical trials.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2001, Volume: 38, Issue:5

    Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Industry; Enalapril; Humans; Irbesartan; Losartan; Research Design; Tetrazoles

2001
Effects of differential blockade of the renin-angiotensin system in postinfarcted rats.
    Fundamental & clinical pharmacology, 2004, Volume: 18, Issue:3

    Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Cyclic GMP; Enalapril; Hemodynamics; Irbesartan; Male; Myocardial Infarction; Rats; Rats, Sprague-Dawley; Tetrazoles; Ventricular Remodeling

2004
Penile angioedema associated with the use of angiotensin-converting-enzyme inhibitors and angiotensin II receptor blockers.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2008, Mar-01, Volume: 65, Issue:5

    Topics: Aged; Angioedema; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Compounds; Enalapril; Glucocorticoids; Humans; Irbesartan; Lisinopril; Male; Middle Aged; Penis; Prednisone; Tetrazoles

2008
Enalapril, irbesartan, and angiotensin-(1-7) prevent atrial tachycardia-induced ionic remodeling.
    International journal of cardiology, 2011, Feb-03, Volume: 146, Issue:3

    Topics: Action Potentials; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Atrial Fibrillation; Biphenyl Compounds; Dogs; Enalapril; Female; Heart Atria; Ion Channels; Irbesartan; Male; Tachycardia; Tetrazoles

2011
[Rapidly progressive renal failure as the onset of an IgA nephropathy in an elderly patient].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2011, Volume: 31, Issue:2

    Topics: Acute Kidney Injury; Adenocarcinoma; Aged; Biphenyl Compounds; Disease Progression; Diuretics; Doxazosin; Drug Therapy, Combination; Enalapril; Furosemide; Glomerulonephritis, IGA; Humans; Irbesartan; Male; Methylprednisolone; Nocturia; Prednisone; Prostatic Neoplasms; Remission Induction; Renal Dialysis; Tetrazoles

2011
Development of eye drops containing antihypertensive drugs: formulation of aqueous irbesartan/γCD eye drops.
    Pharmaceutical development and technology, 2015, Volume: 20, Issue:5

    Topics: Antihypertensive Agents; Biphenyl Compounds; Enalapril; gamma-Cyclodextrins; Irbesartan; Ophthalmic Solutions; Permeability; Solubility; Tetrazoles; Verapamil

2015
IgA nephropathy in a girl with mitochondrial disease.
    Pediatrics international : official journal of the Japan Pediatric Society, 2015, Volume: 57, Issue:2

    Topics: Adolescent; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Biopsy; Biphenyl Compounds; Enalapril; Female; Fluorescent Antibody Technique, Indirect; Glomerulonephritis, IGA; Humans; Irbesartan; Kidney Tubules, Proximal; Microscopy, Electron; Mitochondria; Mitochondrial Diseases; Tetrazoles

2015
chemdatabank.com