avapro and aliskiren

avapro has been researched along with aliskiren in 23 studies

Research

Studies (23)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	11 (47.83)	29.6817
2010's	10 (43.48)	24.3611
2020's	2 (8.70)	2.80

Authors

Authors	Studies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bedigian, MP; Chiang, Y; Gradman, AH; Lins, RL; Nussberger, J; Schmieder, RE	1
Ogiwara, T; Rakugi, H	1
Barton, J; Dicker, P; Jensen, C; Mulcahy, D; Nussberger, J; O'Brien, E; Stanton, A	1
Boye, SW; Engeli, S; Jordan, J; Keefe, DL; Le Breton, S	1
Bigler, H; Bizot, MN; Dieterich, HA; Dole, WP; Howard, D; Vaidyanathan, S; Yeh, C	1
Aubert, JF; Bouzourene, K; Hayoz, D; Mazzolai, L; Nussberger, J; Pellegrin, M	1
Cooper, SA; Demarco, VG; Ferrario, CM; Habibi, J; Hayden, MR; Link, D; Sowers, JR; Stump, CS; Whaley-Connell, A	1
Botha, J; Bush, C; Jung, W; Keefe, DL; Palatini, P; Shlyakhto, E	1
Dicker, P; O'Brien, ET; Stanton, AV	1
Boomsma, F; Danser, AH; Frandsen, E; Juhl, T; Parving, HH; Persson, F; Reinhard, H; Rossing, P; Schalkwijk, C; Stehouwer, CD	1
Charney, A; Delea, TE; Lau, H; Munk, VC; Palmer, JL; Parving, HH; Sofrygin, O; Sullivan, SD; Sung, J	1
Ferrario, CM; Habibi, J; Hayden, MR; Johnson, MS; Nistala, R; Rehmer, N; Schneider, RI; Sowers, JR; Tilmon, R; Whaley-Connell, A	1
Savvatis, K; Schultheiss, HP; Tschöpe, C; Westermann, D	1
Bartlett, M; Dole, WP; Hanefeld, M; Jung, T; Krone, W; Meyer, HF; Prescott, MF; Rajman, I; Yeh, CM	1
Bouhuizen, AM; Chai, W; Danser, AH; de Vries, R; Fekkes, D; Garrelds, IM; Krop, M; Ozünal, ZG	1
Bouhuizen, AM; Danser, AH; Garrelds, IM; Leijten, F; Moltzer, E; van Esch, JH; van Veghel, R	1
Brede, Y; Burnier, M; Lowy, A	1
Barkoudah, E; Danser, AH; Fisher, ND; Hollenberg, NK; Moukarbel, GV; Nussberger, J	1
Danser, AH; Garrelds, IM; Lu, X; Parving, HH; Persson, F; Rossing, P	1
Comi, N; Fuiano, G; Libri, E; Nicotera, R; Pelagi, E; Simeoni, M	1
Li, LJ; Tang, WL; Wang, GM; Wright, JM	1
Pathak, AS; Rojas, M; Stouffer, GA	1

Reviews

4 review(s) available for avapro and aliskiren

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Renin-angiotensin system]. Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64 Suppl 5 Topics: Adipocytes; Amides; Angiotensin-Converting Enzyme 2; Antihypertensive Agents; Biphenyl Compounds; Fumarates; Hypertension; Insulin Resistance; Irbesartan; Metabolic Syndrome; Peptidyl-Dipeptidase A; Prorenin Receptor; Receptors, Angiotensin; Receptors, Cell Surface; Renin-Angiotensin System; Tetrazoles; Vacuolar Proton-Translocating ATPases	2006
Rational of the use of aliskiren in hypertension and beyond. Minerva cardioangiologica, 2009, Volume: 57, Issue:6 Topics: Amides; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Cardiovascular Diseases; Diabetic Nephropathies; Diuretics; Drug Therapy, Combination; Europe; Fumarates; Germany; Heart Failure; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Japan; Prevalence; Prorenin Receptor; Protein Precursors; Randomized Controlled Trials as Topic; Receptors, Cell Surface; Renin; Renin-Angiotensin System; Risk Factors; Tetrazoles; Time Factors; World Health Organization	2009
Renin inhibitors versus angiotensin converting enzyme (ACE) inhibitors for primary hypertension. The Cochrane database of systematic reviews, 2020, 10-22, Volume: 10 Topics: Aged; Amides; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Cardiovascular Diseases; Cause of Death; Female; Fumarates; Heart Rate; Humans; Irbesartan; Kidney Failure, Chronic; Lisinopril; Male; Middle Aged; Myocardial Infarction; Patient Dropouts; Ramipril; Randomized Controlled Trials as Topic; Renin	2020

Trials

10 trial(s) available for avapro and aliskiren

Article	Year
Aliskiren, a novel orally effective renin inhibitor, provides dose-dependent antihypertensive efficacy and placebo-like tolerability in hypertensive patients. Circulation, 2005, Mar-01, Volume: 111, Issue:8 Topics: Administration, Oral; Amides; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Diastole; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fumarates; Humans; Hypertension; Irbesartan; Male; Middle Aged; Placebos; Renin; Substance Withdrawal Syndrome; Systole; Tetrazoles; Treatment Outcome	2005
Aliskiren reduces blood pressure and suppresses plasma renin activity in combination with a thiazide diuretic, an angiotensin-converting enzyme inhibitor, or an angiotensin receptor blocker. Hypertension (Dallas, Tex. : 1979), 2007, Volume: 49, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Amides; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Therapy, Combination; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Patient Compliance; Ramipril; Renin; Sodium Chloride Symporter Inhibitors; Tetrazoles	2007
Direct Renin inhibition with aliskiren in obese patients with arterial hypertension. Hypertension (Dallas, Tex. : 1979), 2007, Volume: 49, Issue:5 Topics: Administration, Oral; Adult; Aged; Amides; Amlodipine; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Diastole; Double-Blind Method; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Obesity; Renin; Systole; Tetrazoles; Treatment Outcome	2007
Maintenance of blood-pressure-lowering effect following a missed dose of aliskiren, irbesartan or ramipril: results of a randomized, double-blind study. Journal of human hypertension, 2010, Volume: 24, Issue:2 Topics: Adult; Aged; Amides; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Brazil; Canada; Double-Blind Method; Drug Administration Schedule; Europe; Female; Fumarates; Humans; Hypertension; Irbesartan; Male; Medication Adherence; Middle Aged; Ramipril; Tetrazoles; Time Factors; Treatment Outcome	2010
Aliskiren monotherapy results in the greatest and the least blood pressure lowering in patients with high- and low-baseline PRA levels, respectively. American journal of hypertension, 2009, Volume: 22, Issue:9 Topics: Amides; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Drug Therapy, Combination; Fumarates; Humans; Hypertension; Irbesartan; Ramipril; Renin; Renin-Angiotensin System; Tetrazoles; Treatment Outcome	2009
Renal effects of aliskiren compared with and in combination with irbesartan in patients with type 2 diabetes, hypertension, and albuminuria. Diabetes care, 2009, Volume: 32, Issue:10 Topics: Aged; Albuminuria; Amides; Antihypertensive Agents; Biphenyl Compounds; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Fumarates; Humans; Hypertension; Irbesartan; Kidney; Male; Middle Aged; Tetrazoles; Treatment Outcome	2009
Comparative efficacy and safety of aliskiren and irbesartan in patients with hypertension and metabolic syndrome. Journal of human hypertension, 2011, Volume: 25, Issue:3 Topics: Adult; Aged; Amides; Antihypertensive Agents; Biphenyl Compounds; Blood Glucose; Cardiovascular Diseases; Double-Blind Method; Female; Fumarates; Humans; Hypertension; Inflammation; Irbesartan; Lipids; Male; Metabolic Syndrome; Middle Aged; Renin; Renin-Angiotensin System; Tetrazoles; Treatment Outcome	2011
Impact of prolonged antihypertensive duration of action on predicted clinical outcomes in imperfectly adherent patients: comparison of aliskiren, irbesartan and ramipril. International journal of clinical practice, 2011, Volume: 65, Issue:2 Topics: Aged; Amides; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Cardiovascular Diseases; Double-Blind Method; Female; Fumarates; Humans; Hypertension; Irbesartan; Male; Medication Adherence; Ramipril; Risk Factors; Tetrazoles; Treatment Outcome	2011
Renal responses to three types of renin-angiotensin system blockers in patients with diabetes mellitus on a high-salt diet: a need for higher doses in diabetic patients? Journal of hypertension, 2011, Volume: 29, Issue:12 Topics: Aldosterone; Amides; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Compounds; Blood Pressure; Captopril; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fumarates; Humans; Irbesartan; Kidney; Male; Middle Aged; Renin-Angiotensin System; Sodium Chloride, Dietary; Tetrazoles; Treatment Outcome	2011
Urinary renin and angiotensinogen in type 2 diabetes: added value beyond urinary albumin? Journal of hypertension, 2013, Volume: 31, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Albumins; Amides; Angiotensinogen; Angiotensins; Antihypertensive Agents; Biphenyl Compounds; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Fumarates; Humans; Irbesartan; Male; Middle Aged; Renin; Renin-Angiotensin System; Tetrazoles	2013

Other Studies

9 other study(ies) available for avapro and aliskiren

Article	Year
Pharmacokinetics of the oral direct renin inhibitor aliskiren alone and in combination with irbesartan in renal impairment. Clinical pharmacokinetics, 2007, Volume: 46, Issue:8 Topics: Administration, Oral; Amides; Biphenyl Compounds; Drug Therapy, Combination; Fumarates; Humans; Irbesartan; Kidney Diseases; Pharmacokinetics; Renin; Tetrazoles	2007
Renin inhibition by aliskiren prevents atherosclerosis progression: comparison with irbesartan, atenolol, and amlodipine. Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:5 Topics: Amides; Amlodipine; Animals; Antihypertensive Agents; Apolipoproteins E; Atenolol; Atherosclerosis; Biphenyl Compounds; Blood Pressure; Cholesterol; Disease Models, Animal; Disease Progression; Female; Fumarates; Heart Rate; Irbesartan; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Renin; Renin-Angiotensin System; Tetrazoles	2008
Effect of renin inhibition and AT1R blockade on myocardial remodeling in the transgenic Ren2 rat. American journal of physiology. Endocrinology and metabolism, 2008, Volume: 295, Issue:1 Topics: Amides; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Genetically Modified; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Fumarates; Irbesartan; Male; Myocardium; NADPH Oxidases; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin; Tetrazoles; Tyrosine; Ventricular Remodeling	2008
Cost-effectiveness of aliskiren in type 2 diabetes, hypertension, and albuminuria. Journal of the American Society of Nephrology : JASN, 2009, Volume: 20, Issue:10 Topics: Albuminuria; Amides; Biphenyl Compounds; Cost-Benefit Analysis; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Progression; Fumarates; Health Care Costs; Humans; Hypertension; Irbesartan; Losartan; Quality-Adjusted Life Years; Tetrazoles	2009
Comparative effect of direct renin inhibition and AT1R blockade on glomerular filtration barrier injury in the transgenic Ren2 rat. American journal of physiology. Renal physiology, 2010, Volume: 298, Issue:3 Topics: Albuminuria; Amides; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Biphenyl Compounds; Blood Pressure; Fumarates; Glomerular Filtration Rate; Hypertension; Irbesartan; Kidney; Membrane Glycoproteins; Membrane Proteins; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Podocytes; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Tetrazoles; Tyrosine	2010
Mast cell degranulation mediates bronchoconstriction via serotonin and not via renin release. European journal of pharmacology, 2010, Aug-25, Volume: 640, Issue:1-3 Topics: Amides; Angiotensinogen; Animals; Biphenyl Compounds; Bronchi; Bronchoconstriction; Captopril; Cell Degranulation; Fumarates; In Vitro Techniques; Irbesartan; Male; Mast Cells; Methacholine Chloride; p-Methoxy-N-methylphenethylamine; Rats; Rats, Sprague-Dawley; Renin; Serotonin; Tetrazoles	2010
Beneficial cardiac effects of the renin inhibitor aliskiren in spontaneously hypertensive rats. Journal of hypertension, 2010, Volume: 28, Issue:10 Topics: Amides; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Biphenyl Compounds; Blood Pressure; Captopril; Disease Models, Animal; Dose-Response Relationship, Drug; Fumarates; Heart; Heart Ventricles; Hypertension; Hypertrophy; Irbesartan; Male; Natriuretic Peptide, Brain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Tetrazoles	2010
Successful Use of Aliskiren in a Case of IgA- Mesangial Glomerulonephritis Unresponsive to Conventional Therapies. Reviews on recent clinical trials, 2019, Volume: 14, Issue:1 Topics: Amides; Biopsy, Needle; Drug Administration Schedule; Drug Resistance, Multiple; Drug Therapy, Combination; Follow-Up Studies; Fumarates; Glomerulonephritis, IGA; Humans; Immunohistochemistry; Immunosuppressive Agents; Irbesartan; Male; Middle Aged; Prednisone; Ramipril; Retreatment; Time Factors; Treatment Outcome	2019
Expression of Cyr61 in ApoE Scientific reports, 2021, 02-11, Volume: 11, Issue:1 Topics: Amides; Amlodipine; Angiotensin II; Animals; Antihypertensive Agents; Apolipoproteins E; Blood Pressure; Cysteine-Rich Protein 61; Fumarates; Gene Expression Regulation; Humans; Hypertension; Irbesartan; Mice; Mice, Knockout; Renal Artery; Renal Artery Obstruction	2021

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