aurintricarboxylic acid and cosalane

aurintricarboxylic acid has been researched along with cosalane in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's11 (44.00)18.2507
2000's11 (44.00)29.6817
2010's3 (12.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cushman, M; De Clercq, E; Golebiewski, WM; Graham, L; Mazumder, A; Pommier, Y; Reymen, D; Rice, WG1
Bader, JP; Buckheit, RW; Clanton, DJ; Cushman, M; Golebiewski, WM; Graham, L; Haugwitz, RD; McMahon, JB; Rice, WG; Weislow, O1
Choo, V1
Cushman, M; Golebiewski, WM; Keyes, RF2
Buckheit, RW; Cushman, M; Fliakas-Boltz, V; Golebiewski, WM; Graham, L; Rice, WG; Turpin, JA1
Anderson, BD; Li, J; Venkatesh, S; Vishnuvajjala, R; Xu, Y1
Gabriel, JL; Mitchell, WM1
Cushman, M; Insaf, S; Rice, WG; Ruell, JA; Schaeffer, CA1
Cushman, M; De Clercq, E; Insaf, S; Pannecouque, C; Paul, G; Rice, WG; Ruell, JA; Schaeffer, CA; Schols, D; Turpin, JA; Williamson, K; Witvrouw, M1
Badr, MZ; Mitra, AK; Udata, C1
Johnston, TP; Kuchimanchi, KR; Mitra, AK; Udata, C1
Mitra, AK; Pal, D; Udata, C1
Buckheit, RW; Casimiro-Garcia, A; Cushman, M; De Clercq, E; Pannecouque, C; Stup, TL; Turpin, JA; Witvrouw, M1
Buckheit, RW; Cushman, M; De Clercq, E; Loftus, TL; Pannecouque, C; Paul, GC; Turpin, JA; Witvrouw, M1
Buckheit, RW; Cushman, M; De Clercq, E; Loftus, TL; Pannecouque, C; Santhosh, KC; Turpin, JA; Witvrouw, M1
Cushman, M; Dong, HF; Howard, OM; Insaf, S; Oppenheim, JJ; Paul, G; Santhosh, KC1
Buckheit, RW; Cushman, M; De Clercq, E; Loftus, TL; Pannecouque, C; Paul, GC; Santhosh, KC; Turpin, JA; Witvrouw, M1
Ahmed, MS; Johnston, TP; Kuchimanchi, KR; Mitra, AK1
Buckheit, RW; Casimiro-Garcia, A; Cushman, M; De Clercq, E; Fanwick, PE; Loftus, TL; Pannecouque, C; Turpin, JA; Witvrouw, M1
Cushman, M; Gandhi, MD; Johnston, TP; Kuchimanchi, KR; Mitra, AK; Santhosh, KC; Sheta, RR1
Cushman, M; Hejchman, E; Mitra, AK; Pal, D; Patel, J; Udata, C1
Li, Z; Liu, X; Zhan, P1
Coghill, JM; Fowler, KA; Hull-Ryde, EA; Janzen, W; Kireev, D; Li, K; Pearce, KH; Porter, MA; Sassano, MF; Simpson, CD; Suto, MJ1
Aubé, J; Bruce, DW; Coghill, JM; Fowler, KA; Li, K; Moorman, NJ; Whitehurst, CB1

Reviews

1 review(s) available for aurintricarboxylic acid and cosalane

ArticleYear
Cosalane and its analogues: a unique class of anti-HIV agents.
    Mini reviews in medicinal chemistry, 2010, Volume: 10, Issue:10

    Topics: Anti-HIV Agents; Aurintricarboxylic Acid; CD4 Antigens; HIV Envelope Protein gp120; Humans; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

2010

Other Studies

24 other study(ies) available for aurintricarboxylic acid and cosalane

ArticleYear
Cosalane analogues with enhanced potencies as inhibitors of HIV-1 protease and integrase.
    Journal of medicinal chemistry, 1995, Feb-03, Volume: 38, Issue:3

    Topics: Amino Acid Sequence; Antiviral Agents; Aurintricarboxylic Acid; Cell Line; DNA Nucleotidyltransferases; Herpesviridae; HIV Protease Inhibitors; HIV-1; Humans; Integrases; Microbial Sensitivity Tests; Molecular Sequence Data; Virus Replication

1995
Design, synthesis, and biological evaluation of cosalane, a novel anti-HIV agent which inhibits multiple features of virus reproduction.
    Journal of medicinal chemistry, 1994, Sep-16, Volume: 37, Issue:19

    Topics: Antiviral Agents; Aurintricarboxylic Acid; B-Lymphocytes; Cell Fusion; Cells, Cultured; DNA, Viral; HeLa Cells; HIV Infections; HIV-1; Humans; Macrophages; Phenotype; T-Lymphocytes; Virion; Virus Replication; Zidovudine

1994
Anti-HIV activity of cosalane.
    Lancet (London, England), 1993, Sep-18, Volume: 342, Issue:8873

    Topics: Antiviral Agents; Aurintricarboxylic Acid; Cells, Cultured; HIV-1; HIV-2; Humans

1993
Correlation of anti-HIV potency with lipophilicity in a series of cosalane analogs having normal alkenyl and phosphodiester chains as cholestane replacements.
    Journal of medicinal chemistry, 1996, Jan-19, Volume: 39, Issue:2

    Topics: Antiviral Agents; Aurintricarboxylic Acid; Cells, Cultured; Cytopathogenic Effect, Viral; HIV-1; Humans; Lipid Metabolism; Spectrum Analysis

1996
Synthesis and biological evaluation of certain alkenyldiarylmethanes as anti-HIV-1 agents which act as non-nucleoside reverse transcriptase inhibitors.
    Journal of medicinal chemistry, 1996, Aug-02, Volume: 39, Issue:16

    Topics: Amino Acid Sequence; Antiviral Agents; Aurintricarboxylic Acid; Benzoates; Binding Sites; Biphenyl Compounds; Cells, Cultured; Didanosine; Drug Resistance, Microbial; HIV Core Protein p24; HIV Reverse Transcriptase; HIV-1; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase

1996
Intrinsic solubility estimation and pH-solubility behavior of cosalane (NSC 658586), an extremely hydrophobic diprotic acid.
    Pharmaceutical research, 1996, Volume: 13, Issue:10

    Topics: Anti-HIV Agents; Aurintricarboxylic Acid; Chemical Phenomena; Chemistry, Physical; Hydrogen-Ion Concentration; Ions; Kinetics; Solubility

1996
Exploration of the effects of linker chain modifications on anti-HIV activities in a series of cosalane analogues.
    Bioorganic & medicinal chemistry, 1996, Volume: 4, Issue:10

    Topics: Anti-HIV Agents; Antiviral Agents; Aurintricarboxylic Acid; Models, Molecular; Phosphorylation; Structure-Activity Relationship

1996
Functional design of potential inhibitors of human immunodeficiency virus (HIV) binding to CD4+ target cells: a molecular model of gp120 predicts ligand binding.
    Drug design and discovery, 1996, Volume: 14, Issue:2

    Topics: Aurintricarboxylic Acid; Binding Sites; CD4 Antigens; Computer Simulation; Drug Design; HIV; HIV Envelope Protein gp120; Ligands; Models, Molecular; Suramin; Tannins

1996
Synthesis of a cosalane analog with an extended polyanionic pharmacophore conferring enhanced potency as an anti-HIV agent.
    Bioorganic & medicinal chemistry letters, 1998, Apr-07, Volume: 8, Issue:7

    Topics: Anti-HIV Agents; Aurintricarboxylic Acid; CD4 Antigens; Drug Design; HIV-1; Humans; Models, Molecular; Molecular Conformation; Molecular Structure; Protein Conformation; Structure-Activity Relationship; Tumor Cells, Cultured

1998
Extension of the polyanionic cosalane pharmacophore as a strategy for increasing anti-HIV potency.
    Journal of medicinal chemistry, 1999, May-20, Volume: 42, Issue:10

    Topics: Animals; Anti-HIV Agents; Aurintricarboxylic Acid; Benzoates; CD4 Antigens; Cell Line; Cholestanes; HIV-1; HIV-2; Humans; Models, Molecular; Protein Binding; Structure-Activity Relationship

1999
Disposition of cosalane, a novel anti-HIV agent, in isolated perfused rat livers.
    Drug metabolism and disposition: the biological fate of chemicals, 1999, Volume: 27, Issue:8

    Topics: Animals; Anti-HIV Agents; Aurintricarboxylic Acid; Chromatography, High Pressure Liquid; Enzyme Induction; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Male; Protein Binding; Rats; Rats, Sprague-Dawley

1999
Pharmacokinetics, biliary excretion, and tissue distribution of novel anti-HIV agents, cosalane and dihydrocosalane, in Sprague-Dawley rats.
    Drug metabolism and disposition: the biological fate of chemicals, 2000, Volume: 28, Issue:4

    Topics: Administration, Oral; Animals; Anti-HIV Agents; Aurintricarboxylic Acid; Bile; Chromatography, High Pressure Liquid; Enterohepatic Circulation; Injections, Intravenous; Male; Models, Biological; Rats; Rats, Sprague-Dawley; Spectrophotometry, Ultraviolet; Tissue Distribution

2000
Transport of cosalane-a highly lipophilic novel anti-HIV agent-across caco-2 cell monolayers.
    Journal of pharmaceutical sciences, 2000, Volume: 89, Issue:6

    Topics: Anti-HIV Agents; Aurintricarboxylic Acid; Biological Availability; Caco-2 Cells; Humans; Solubility

2000
Synthesis and anti-HIV activity of cosalane analogues incorporating nitrogen in the linker chain.
    Bioorganic & medicinal chemistry, 2000, Volume: 8, Issue:1

    Topics: Anti-HIV Agents; Aurintricarboxylic Acid; Cell Line; Cytopathogenic Effect, Viral; HIV-1; HIV-2; Humans; Magnetic Resonance Spectroscopy; Nitrogen; Spectrometry, Mass, Fast Atom Bombardment

2000
Identification of optimal anion spacing for anti-HIV activity in a series of cosalane tetracarboxylates.
    Bioorganic & medicinal chemistry letters, 2000, Sep-18, Volume: 10, Issue:18

    Topics: Anti-HIV Agents; Aurintricarboxylic Acid; Carboxylic Acids; CD4 Antigens; Cell Line; Cell Survival; HIV-1; HIV-2; Humans; Models, Molecular; Protein Binding; Structure-Activity Relationship

2000
Anti-HIV activity of a series of cosalane amino acid conjugates.
    Bioorganic & medicinal chemistry letters, 2000, Nov-20, Volume: 10, Issue:22

    Topics: Amino Acids; Anti-HIV Agents; Aurintricarboxylic Acid; CD4 Antigens; Cell Line; Humans; Microbial Sensitivity Tests

2000
Inhibition of RANTES/CCR1-mediated chemotaxis by cosalane and related compounds.
    Bioorganic & medicinal chemistry letters, 2001, Jan-08, Volume: 11, Issue:1

    Topics: Acetylation; Anti-HIV Agents; Aurintricarboxylic Acid; Cell Line; Chemokine CCL5; Chemokine CXCL12; Chemokines, CXC; Chemotaxis; Humans; Lymphocytes; Molecular Structure; Protein Binding; Receptors, CCR1; Receptors, Chemokine; Transfection

2001
Correlation of anti-HIV activity with anion spacing in a series of cosalane analogues with extended polycarboxylate pharmacophores.
    Journal of medicinal chemistry, 2001, Mar-01, Volume: 44, Issue:5

    Topics: Anions; Anti-HIV Agents; Aurintricarboxylic Acid; CD4 Antigens; Cell Line; HIV-1; Humans; Models, Molecular; Structure-Activity Relationship

2001
Binding of cosalane--a novel highly lipophilic anti-HIV agent--to albumin and glycoprotein.
    Journal of pharmaceutical sciences, 2001, Volume: 90, Issue:5

    Topics: Animals; Anti-HIV Agents; Aurintricarboxylic Acid; Blood Proteins; Cattle; Chromatography, Gel; Humans; Mucins; Orosomucoid; Rats; Serum Albumin; Serum Albumin, Bovine

2001
Synthesis and anti-HIV activity of cosalane analogues incorporating two dichlorodisalicylmethane pharmacophore fragments.
    Bioorganic & medicinal chemistry, 2001, Volume: 9, Issue:11

    Topics: Anti-HIV Agents; Aurintricarboxylic Acid; CD4 Antigens; Cell Survival; Drug Design; HIV Envelope Protein gp120; HIV-1; HIV-2; Humans; Inhibitory Concentration 50; Salicylates; Structure-Activity Relationship; Tumor Cells, Cultured

2001
Intestinal absorption and biodistribution of cosalane and its amino acid conjugates: novel anti-HIV agents.
    International journal of pharmaceutics, 2002, Jan-14, Volume: 231, Issue:2

    Topics: Animals; Anti-HIV Agents; Aurintricarboxylic Acid; Intestinal Absorption; Male; Rats; Rats, Sprague-Dawley; Tissue Distribution

2002
Enhanced transport of a novel anti-HIV agent--cosalane and its congeners across human intestinal epithelial (Caco-2) cell monolayers.
    International journal of pharmaceutics, 2003, Jan-02, Volume: 250, Issue:1

    Topics: Anti-HIV Agents; Aurintricarboxylic Acid; Biological Transport; Caco-2 Cells; Cyclodextrins; Glycerol; Humans; Permeability; Solubility

2003
Identification of Cosalane as an Inhibitor of Human and Murine CC-Chemokine Receptor 7 Signaling via a High-Throughput Screen.
    SLAS discovery : advancing life sciences R & D, 2018, Volume: 23, Issue:10

    Topics: Animals; Aurintricarboxylic Acid; Cell Line; Chemotaxis; Drug Design; High-Throughput Screening Assays; Humans; Ligands; Mice; Molecular Structure; Receptors, CCR7; Receptors, G-Protein-Coupled; Signal Transduction; Structure-Activity Relationship; T-Lymphocytes

2018
The Ex Vivo Treatment of Donor T Cells with Cosalane, an HIV Therapeutic and Small-Molecule Antagonist of CC-Chemokine Receptor 7, Separates Acute Graft-versus-Host Disease from Graft-versus-Leukemia Responses in Murine Hematopoietic Stem Cell Transplanta
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2019, Volume: 25, Issue:6

    Topics: Acute Disease; Animals; Aurintricarboxylic Acid; Graft vs Host Disease; Graft vs Leukemia Effect; Hematopoietic Stem Cell Transplantation; Humans; Mice; Receptors, CCR7; T-Lymphocytes; Tissue Donors; Transplantation Conditioning

2019