aureothin and 4-nitrobenzoic-acid

aureothin has been researched along with 4-nitrobenzoic-acid* in 2 studies

Other Studies

2 other study(ies) available for aureothin and 4-nitrobenzoic-acid

Article	Year
Multifactorial control of iteration events in a modular polyketide assembly line. Angewandte Chemie (International ed. in English), 2013, May-10, Volume: 52, Issue:20 Topics: Chromones; Computational Biology; Models, Molecular; Nitrobenzoates; Polyketide Synthases; Polyketides; Protein Engineering; Streptomyces	2013
Biosynthetic origin of the rare nitroaryl moiety of the polyketide antibiotic aureothin: involvement of an unprecedented N-oxygenase. Journal of the American Chemical Society, 2004, Mar-31, Volume: 126, Issue:12 The antibiotic aureothin is a rare natural nitroaromatic compound produced by Streptomyces thioluteus. By labeling experiments, we demonstrate for the first time that p-nitrobenzoate (PNBA) serves as a polyketide synthase starter unit. Cloning, heterologous expression, and inactivation experiments reveal that this unusual primer is synthesized from p-aminobenzoate (PABA) by means of AurF, a novel N-oxygenase. Topics: Anti-Bacterial Agents; Chromones; Genes, Bacterial; Molecular Structure; Multigene Family; Mutagenesis; Nitrobenzoates; Oxygenases; Streptomyces	2004

Article

Year

Multifactorial control of iteration events in a modular polyketide assembly line.

Angewandte Chemie (International ed. in English), 2013, May-10, Volume: 52, Issue:20

Topics: Chromones; Computational Biology; Models, Molecular; Nitrobenzoates; Polyketide Synthases; Polyketides; Protein Engineering; Streptomyces

2013

Biosynthetic origin of the rare nitroaryl moiety of the polyketide antibiotic aureothin: involvement of an unprecedented N-oxygenase.

Journal of the American Chemical Society, 2004, Mar-31, Volume: 126, Issue:12

The antibiotic aureothin is a rare natural nitroaromatic compound produced by Streptomyces thioluteus. By labeling experiments, we demonstrate for the first time that p-nitrobenzoate (PNBA) serves as a polyketide synthase starter unit. Cloning, heterologous expression, and inactivation experiments reveal that this unusual primer is synthesized from p-aminobenzoate (PABA) by means of AurF, a novel N-oxygenase.

Topics: Anti-Bacterial Agents; Chromones; Genes, Bacterial; Molecular Structure; Multigene Family; Mutagenesis; Nitrobenzoates; Oxygenases; Streptomyces

2004