Page last updated: 2024-09-05

atropine and warfarin

atropine has been researched along with warfarin in 30 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(warfarin)
Trials
(warfarin)
Recent Studies (post-2010) (warfarin)
26,7111,2591,69736,5732,14314,728

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)warfarin (IC50)
Vitamin K epoxide reductase complex subunit 1 Homo sapiens (human)0.0088

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19909 (30.00)18.7374
1990's1 (3.33)18.2507
2000's9 (30.00)29.6817
2010's11 (36.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Duffy, EM; Jorgensen, WL1
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Bryan, J; Cheung, CY; Haggarty, SJ; Healey, D; Kim, S; Kokel, D; Laggner, C; Macrae, CA; Mateus, R; Peterson, RT; Shoichet, B; Werdich, AA; White, R1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Azuma, H; Fujiwara, M; Hattori, K1
Crone, HD1
Altland, K; Goedee, HW1
Fujiwara, M; Lee, WH1
Blount, AW; Miller, DS1
Iwaki, R; Kitagawa, H; Saito, H; Suwa, Y; Yamada, M1
Schrogie, JJ; Solomon, HM1
Radić, Z; Taylor, P1
Chen, X; Luo, Q; Ni, J; Wang, H; Zhang, Q; Zou, H1
Abbas, S; Bashir, S; Gilani, AH; Khan, A; Mehmood, MH1
Gilani, AH; Mehmood, MH; Rehman, A; Rehman, NU1
Borovik, A; Dance, S; Francis, IC; Gupta, R; Ooi, KG; Wang, SB1

Reviews

2 review(s) available for atropine and warfarin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Genetically dependent variability of drug effects].
    Medizinische Klinik, 1970, Aug-28, Volume: 65, Issue:35

    Topics: Anemia, Hemolytic; Anesthesia, General; Anesthetics; Animals; Antipyrine; Apnea; Atropine; Body Temperature; Coumarins; Cyanosis; Deficiency Diseases; Dexamethasone; Dogs; Drug Tolerance; Enzymes; Female; Glucosephosphate Dehydrogenase; Humans; Intraocular Pressure; Isonicotinic Acids; Male; Meperidine; Mice; Oxyphenbutazone; Pharmacogenetics; Phenacetin; Phenylbutazone; Phenytoin; Proteins; Rabbits; Rats; Succinylcholine

1970

Other Studies

28 other study(ies) available for atropine and warfarin

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Rapid behavior-based identification of neuroactive small molecules in the zebrafish.
    Nature chemical biology, 2010, Volume: 6, Issue:3

    Topics:

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
[Mechanism of spasmolytic action of 4-methylumbelliferone].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1973, Volume: 69, Issue:2

    Topics: Ampulla of Vater; Animals; Aorta, Thoracic; Atropine; Catechol O-Methyltransferase Inhibitors; Coumarins; Enzyme Activation; In Vitro Techniques; Liver; Male; Muscle Contraction; Muscle, Smooth; Papaverine; Parasympatholytics; Pyrogallol; Rabbits; Rats

1973
Can allosteric effectors of acetylcholinesterase control the rate of ageing of the phosphonylated enzyme?
    Biochemical pharmacology, 1974, Jan-15, Volume: 23, Issue:2

    Topics: Acetylcholinesterase; Allyl Compounds; Animals; Atropine; Cattle; Coumarins; Erythrocytes; Gallamine Triethiodide; Rabbits; Sarin; Toxiferine; Tropanes; Tubocurarine

1974
Spasmolytic action of 4-methylumbelliferone in isolated guinea-pig's gallbladder.
    Japanese journal of pharmacology, 1971, Volume: 21, Issue:6

    Topics: Acetylcholine; Animals; Atropine; Barium; Coumarins; Diphenhydramine; Gallbladder; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Papaverine; Parasympatholytics

1971
Atrial fibrillation. II.
    British medical journal, 1971, Jul-31, Volume: 3, Issue:5769

    Topics: Atrial Fibrillation; Atropine; Digoxin; Electric Countershock; Humans; Male; Middle Aged; Mitral Valve Stenosis; Myocardial Infarction; Ouabain; Warfarin

1971
Quinidine-induced recurrent ventricular fibrillation: (quinidine syncope) treated with transvenous pacemaker.
    Southern medical journal, 1971, Volume: 64, Issue:5

    Topics: Adult; Atrial Fibrillation; Atropine; Blood Cell Count; Chlorpromazine; Coumarins; Creatine Kinase; Digitalis Glycosides; Diuretics; Electric Countershock; Electrocardiography; Female; Heart Valve Prosthesis; Humans; L-Lactate Dehydrogenase; Lactates; Lidocaine; Mitral Valve Stenosis; Pacemaker, Artificial; Paranoid Disorders; Pneumonia; Potassium Chloride; Quinidine; Rheumatic Heart Disease; Syncope; Ventricular Fibrillation

1971
[Studies on new rodenticides of courmarin derivatives. (5). Toxicological studies on T1-coumarin-3-carboxylate].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1965, Jul-20, Volume: 61, Issue:4

    Topics: Animals; Atropine; Coumarins; Female; In Vitro Techniques; Mice; Pregnancy; Pregnancy, Animal; Rats; Rodenticides

1965
The effect of various drugs on the binding of warfarin-14C to human albumin.
    Biochemical pharmacology, 1967, Jul-07, Volume: 16, Issue:7

    Topics: Atropine; Butyrates; Carbon Isotopes; Phenethylamines; Phenylbutazone; Protein Binding; Serum Albumin; Sulfaphenazole; Thyroxine; Warfarin

1967
The influence of peripheral site ligands on the reaction of symmetric and chiral organophosphates with wildtype and mutant acetylcholinesterases.
    Chemico-biological interactions, 1999, May-14, Volume: 119-120

    Topics: Acetylation; Acetylcholinesterase; Alkaloids; Animals; Atropine; Binding Sites; Cholinesterase Inhibitors; Coumarins; Dichlorvos; Gallamine Triethiodide; Isoquinolines; Kinetics; Ligands; Mice; Mutagenesis, Site-Directed; Organophosphates; Organophosphorus Compounds; Paraoxon; Phosphorylation; Propidium; Stereoisomerism; Umbelliferones

1999
Synthesis and characteristics of the human serum albumin-triazine chiral stationary phase.
    Chirality, 2000, Volume: 12, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Atropine; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Fenoprofen; Glutamic Acid; Humans; Ibuprofen; Naproxen; Protein Binding; Serum Albumin; Silicon Dioxide; Spectrophotometry, Ultraviolet; Stereoisomerism; Triazines; Tryptophan; Warfarin

2000
Gastrointestinal stimulant effect of Urginea indica Kunth. and involvement of muscarinic receptors.
    Phytotherapy research : PTR, 2012, Volume: 26, Issue:5

    Topics: Alkaloids; Animals; Atropine; Calcium Channel Blockers; Cholinergic Agents; Constipation; Coumarins; Dose-Response Relationship, Drug; Drimia; Female; Gastrointestinal Motility; Guinea Pigs; Ileum; Jejunum; Laxatives; Male; Mice; Muscle Contraction; Phytotherapy; Plant Extracts; Plant Roots; Plants, Medicinal; Rabbits; Receptors, Muscarinic; Tannins

2012
Studies on prokinetic, laxative and spasmodic activities of Phyllanthus emblica in experimental animals.
    Phytotherapy research : PTR, 2013, Volume: 27, Issue:7

    Topics: Alkaloids; Animals; Atropine; Constipation; Coumarins; Dyspepsia; Guinea Pigs; Ileum; Jejunum; Laxatives; Mice; Muscle Contraction; Parasympatholytics; Phyllanthus emblica; Plant Extracts; Rabbits; Receptors, Muscarinic; Saponins; Sterols; Tannins; Terpenes

2013
Spontaneous hyphaema secondary to bleeding from an iris vascular tuft in a patient with a supratherapeutic International normalised ratio: case report.
    BMC ophthalmology, 2015, Jun-14, Volume: 15

    Topics: Aged, 80 and over; Anticoagulants; Antihypertensive Agents; Atropine; Eye Hemorrhage; Female; Glucocorticoids; Hamartoma; Humans; Hyphema; International Normalized Ratio; Iris Diseases; Mydriatics; Ophthalmic Solutions; Prednisolone; Pulmonary Embolism; Warfarin

2015