atropine has been researched along with vx in 37 studies
| Studies (atropine) | Trials (atropine) | Recent Studies (post-2010) (atropine) | Studies (vx) | Trials (vx) | Recent Studies (post-2010) (vx) |
|---|---|---|---|---|---|
| 26,711 | 1,259 | 1,697 | 476 | 4 | 206 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (5.41) | 18.7374 |
| 1990's | 12 (32.43) | 18.2507 |
| 2000's | 7 (18.92) | 29.6817 |
| 2010's | 12 (32.43) | 24.3611 |
| 2020's | 4 (10.81) | 2.80 |
| Authors | Studies |
|---|---|
| Dettbarn, WD; Gupta, RC | 1 |
| Anderson, DR; Harris, LW; Koplovitz, I; Lennox, WJ; Stewart, JR | 1 |
| Fiekers, JF; Heppner, TJ | 1 |
| Anderson, DR; Harris, LW; Lennox, WJ; Solana, RP; Talbot, BG | 1 |
| Albuquerque, EX; Aracava, Y; Boyne, AF; Deshpande, SS; Idriss, M; Kawabuchi, M; Rickett, DL | 1 |
| Tanasijević, D | 1 |
| Szinicz, L; Worek, F | 1 |
| Kirchner, T; Szinicz, L; Worek, F | 1 |
| Koplovitz, I; Stewart, JR | 1 |
| Dube, SN; Kumar, D; Mazumder, PK | 1 |
| Kassa, J; Vachek, J | 1 |
| Albuquerque, EX; Aracava, Y; Chebabo, SR; Rocha, ES; Santos, MD | 1 |
| Cao, CJ; Eldefrawi, AT; Eldefrawi, ME; Katz, EJ; Menking, DE; Mioduszewski, RJ; Valdes, JJ | 1 |
| Anderson, RS; Broomfield, CA; Duysen, EG; Li, B; Lockridge, O; Schopfer, LM; Xie, W | 1 |
| Benschop, HP; Lander, BJ; Langenberg, JP; van der Schans, MJ; van der Wiel, H | 1 |
| Newmark, J | 1 |
| Barak, D; Pittel, Z; Segall, Y | 1 |
| Hrobak, PK | 1 |
| Koplovitz, I; Maxwell, DM; Sweeney, RE; Worek, F | 1 |
| Clark, MG; Finneran, K; Hilmas, CJ; Poole, MJ; Williams, PT | 1 |
| Cui, W; Ge, X; Luo, W; Wang, H | 1 |
| Joosen, MJ; van der Schans, MJ; van Helden, HP | 1 |
| Bohnert, S; Mikler, J; Reiter, G; Sawyer, TW; Tenn, C; Thiermann, H; Weatherby, K; Worek, F | 1 |
| Bajgar, J; Caisberger, F; Karasova, JZ; Kassa, J; Sepsova, V | 1 |
| Armstrong, SJ; Docx, CJ; Green, AC; Mumford, H; Price, ME; Tattersall, JE | 1 |
| Kehe, K; Thiermann, H; Worek, F | 1 |
| Armstrong, SJ; Green, AC; Mann, TM; Price, ME; Rice, H; Tattersall, JEH | 1 |
| Babin, MC; Jett, DA; Platoff, GE; Snider, TH; Yeung, DT | 1 |
| Egoz, I; Gore, A; Grauer, E; Nili, U | 1 |
| Armstrong, SJ; Cook, AR; Emery, E; Flint, D; Mann, T; Price, ME; Rice, H; Roughley, N; Stubbs, S; Tattersall, JEH; Whitmore, C | 1 |
| Emery, ER; Green, AC; Laws, TR; Mann, TM; McColm, RR; Perrott, RL; Price, ME; Rice, H; Tattersall, JEH; Whitmore, CL | 1 |
| Bloch-Shilderman, E; Cohen, L; Egoz, I; Gez, R; Gutman, H; Nili, U; Rabinovitz, I; Yacov, G | 1 |
| Barry, J; Bohnert, S; Cochrane, L; Cornelissen, AS; Joosen, MJA; Kentrop, J; Klaassen, SD; Savransky, V; van Groningen, T | 1 |
| Bucht, A; Forsberg, E; Thors, L; Wigenstam, E | 1 |
| Cornelissen, AS; Garcia, EE; Joosen, MJA; Laney, J; Raulli, RE | 1 |
| Artursson, E; Bucht, A; Thors, L; Wigenstam, E | 1 |
2 review(s) available for atropine and vx
| Article | Year |
|---|---|
Therapy for nerve agent poisoning.
Topics: Antidotes; Atropine; Chemical Warfare Agents; Humans; Neurotoxicity Syndromes; Neurotoxins; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Pralidoxime Compounds; Pyridostigmine Bromide; Sarin; Soman | 2004 |
Limitations and challenges in treatment of acute chemical warfare agent poisoning.
Topics: Antidotes; Atropine; Chemical Warfare; Chemical Warfare Agents; Cholinesterase Inhibitors; Decontamination; Humans; Mustard Gas; Organothiophosphorus Compounds; Oximes; Sarin | 2013 |
35 other study(ies) available for atropine and vx
| Article | Year |
|---|---|
Potential of memantine, D-tubocurarine, and atropine in preventing acute toxic myopathy induced by organophosphate nerve agents: soman, sarin, tabun and VX.
Topics: Acetylcholinesterase; Acute Disease; Animals; Atropine; Cholinesterase Inhibitors; Male; Memantine; Muscular Diseases; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Rats; Rats, Sprague-Dawley; Sarin; Soman; Tubocurarine | 1992 |
Reduction by pyridostigmine pretreatment of the efficacy of atropine and 2-PAM treatment of sarin and VX poisoning in rodents.
Topics: Acetylcholinesterase; Animals; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Female; Guinea Pigs; Male; Mice; Mice, Inbred ICR; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Pralidoxime Compounds; Pyridostigmine Bromide; Sarin | 1992 |
The effects of irreversible acetylcholinesterase inhibitors on transmission through sympathetic ganglia of the bullfrog.
Topics: Acetylcholine; Action Potentials; Animals; Atropine; Carbachol; Cholinesterase Inhibitors; Ganglia, Sympathetic; Organothiophosphorus Compounds; Rana catesbeiana; Sarin; Soman; Synaptic Transmission | 1991 |
Physostigmine (alone and together with adjunct) pretreatment against soman, sarin, tabun and VX intoxication.
Topics: Animals; Atropine; Benztropine; Cholinesterase Inhibitors; Female; Guinea Pigs; Lethal Dose 50; Male; Organophosphates; Organothiophosphorus Compounds; Physostigmine; Sarin; Soman; Trihexyphenidyl | 1991 |
Multiple actions of anticholinesterase agents on chemosensitive synapses: molecular basis for prophylaxis and treatment of organophosphate poisoning.
Topics: Animals; Antidotes; Atropine; Cholinesterase Inhibitors; Female; Ganglionic Blockers; Grasshoppers; In Vitro Techniques; Muscle Contraction; Organophosphate Poisoning; Organothiophosphorus Compounds; Physostigmine; Rana pipiens; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Sarin; Synapses | 1985 |
[The effect of atropine, Hi-6 and diazepam on the levels and metabolism of monoamines in the brain of rats poisoned with VX].
Topics: Animals; Atropine; Caudate Nucleus; Cholinesterase Inhibitors; Diazepam; Neurotransmitter Agents; Organothiophosphorus Compounds; Oximes; Pyridinium Compounds; Rats | 1986 |
Cardiorespiratory function in nerve agent poisoned and oxime + atropine treated guinea-pigs: effect of pyridostigmine pretreatment.
Topics: Animals; Atropine; Cholinesterase Inhibitors; Drug Synergism; Female; Guinea Pigs; Heart Function Tests; Organothiophosphorus Compounds; Oximes; Pyridostigmine Bromide; Respiration; Respiratory Function Tests; Sarin | 1995 |
Treatment of nerve gas poisoning.
Topics: Anticonvulsants; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Gases; Humans; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Pralidoxime Compounds; Pyridostigmine Bromide; Respiratory Protective Devices; Sarin; Soman | 1995 |
Effect of atropine, HLö 7 and HI 6 on respiratory and circulatory function in guinea-pigs poisoned by O-ethyl S-[2-(diisopropylamino) ethyl] methylphosponothioate (VX).
Topics: Acetylcholinesterase; Animals; Atropine; Brain; Cholinesterase Inhibitors; Cholinesterase Reactivators; Drug Combinations; Erythrocytes; Female; Guinea Pigs; Hemodynamics; Organothiophosphorus Compounds; Oximes; Poisoning; Pyridines; Pyridinium Compounds; Respiration | 1994 |
A comparison of the efficacy of HI6 and 2-PAM against soman, tabun, sarin, and VX in the rabbit.
Topics: Animals; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diazepam; Lethal Dose 50; Male; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Poisoning; Pralidoxime Compounds; Pyridinium Compounds; Pyridostigmine Bromide; Rabbits; Sarin; Soman; Specific Pathogen-Free Organisms | 1994 |
Cardiorespiratory and neuromuscular effects of O-ethyl S--2-(diisopropylamino) ethyl- methylphosphonothioate (VX) in rats.
Topics: Adrenalectomy; Animals; Atropine; Blood Pressure; Bronchi; Bronchoconstriction; Cardiovascular System; Carotid Arteries; Chemical Warfare Agents; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Heart Rate; Male; Muscle, Skeletal; Neuromuscular Junction; Organothiophosphorus Compounds; Parasympatholytics; Rats; Rats, Wistar; Sympatholytics; Synaptic Transmission; Tolazoline; Trachea; Vagotomy | 1997 |
[The effect of parasympatholytics on the therapeutic effectiveness of the oxime HI-6 against organophosphorus compounds (Soman, substance VX, Fosdrin) in mice].
Topics: Animals; Antidotes; Atropine; Benactyzine; Biperiden; Cholinesterase Reactivators; Male; Mevinphos; Mice; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Parasympatholytics; Pyridinium Compounds; Soman | 1997 |
Low concentrations of the organophosphate VX affect spontaneous and evoked transmitter release from hippocampal neurons: toxicological relevance of cholinesterase-independent actions.
Topics: Animals; Atropine; Calcium; Cells, Cultured; Cholinesterases; Dose-Response Relationship, Drug; Electrophysiology; Evoked Potentials; Female; gamma-Aminobutyric Acid; Glutamates; Hippocampus; Neurons; Organophosphorus Compounds; Organothiophosphorus Compounds; Patch-Clamp Techniques; Pregnancy; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Tetrodotoxin | 1999 |
Cytotoxicity of organophosphate anticholinesterases.
Topics: Acetylcholinesterase; Atropine; Biotransformation; Chemical Warfare Agents; Chlorpyrifos; Cholinesterase Inhibitors; Humans; Insecticides; Organothiophosphorus Compounds; Phenobarbital; Receptors, Muscarinic | 1999 |
Evidence for nonacetylcholinesterase targets of organophosphorus nerve agent: supersensitivity of acetylcholinesterase knockout mouse to VX lethality.
Topics: Acetylcholinesterase; Aging; Animals; Atropine; Behavior, Animal; Body Temperature; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterases; Hair; Hand Strength; Lethal Dose 50; Mice; Mice, Knockout; Motor Activity; Muscarinic Antagonists; Organothiophosphorus Compounds; Tissue Distribution; Tremor; Vasodilation | 2001 |
Toxicokinetics of the nerve agent (+/-)-VX in anesthetized and atropinized hairless guinea pigs and marmosets after intravenous and percutaneous administration.
Topics: Acetylcholinesterase; Administration, Topical; Anesthesia; Animals; Atropine; Callithrix; Chemical Warfare Agents; Chromatography, Gas; Chromatography, High Pressure Liquid; Electrochemistry; Guinea Pigs; Injections, Intravenous; Kinetics; Lethal Dose 50; Male; Muscarinic Antagonists; Organothiophosphorus Compounds; Stereoisomerism | 2003 |
Function-specific blockage of M(1) and M(3) muscarinic acetylcholine receptors by VX and echothiophate.
Topics: Animals; Atropine; CHO Cells; Cholinesterase Inhibitors; Colforsin; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Echothiophate Iodide; Muscarinic Agonists; Muscarinic Antagonists; N-Methylscopolamine; Organothiophosphorus Compounds; Oxotremorine; Phosphatidylinositols; Protein Binding; Receptor, Muscarinic M1; Receptor, Muscarinic M3; Transfection; Tritium | 2006 |
Nerve agents: implications for anesthesia providers.
Topics: Antidotes; Atropine; Chemical Terrorism; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Decontamination; Humans; Muscarinic Antagonists; Nurse Anesthetists; Nurse's Role; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Pralidoxime Compounds; Sarin; Soman; Time Factors | 2008 |
A structure-activity analysis of the variation in oxime efficacy against nerve agents.
Topics: Acetylcholinesterase; Animals; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Erythrocytes; Guinea Pigs; Linear Models; Male; Obidoxime Chloride; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Sarin; Structure-Activity Relationship | 2008 |
Galantamine is a novel post-exposure therapeutic against lethal VX challenge.
Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diaphragm; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroencephalography; Erythrocytes; Galantamine; Guinea Pigs; Male; Muscle Fatigue; Muscle Tonus; Neurotoxicity Syndromes; Organothiophosphorus Compounds; Paralysis; Phrenic Nerve; Pralidoxime Compounds; Seizures; Time Factors | 2009 |
Targeting cholinesterase inhibitor poisoning with a novel blocker against both nicotinic and muscarinic receptors.
Topics: Animals; Atropine; Benzilates; Cell Line; Cholinergic Antagonists; Cholinesterase Inhibitors; Guinea Pigs; Membrane Potentials; Mice; Organothiophosphorus Compounds; Patch-Clamp Techniques; Quinuclidinyl Benzilate; Radioligand Assay; Receptors, Muscarinic; Receptors, Nicotinic; Sarin | 2010 |
Percutaneous exposure to the nerve agent VX: Efficacy of combined atropine, obidoxime and diazepam treatment.
Topics: Animals; Antidotes; Atropine; Chemical Warfare Agents; Chromatography, High Pressure Liquid; Diazepam; Guinea Pigs; Obidoxime Chloride; Organothiophosphorus Compounds; Skin | 2010 |
The therapeutic use of localized cooling in the treatment of VX poisoning.
Topics: Animals; Antidotes; Atropine; Chemical Warfare Agents; Cryotherapy; Male; Organothiophosphorus Compounds; Swine; Time Factors | 2011 |
A comparison of the reactivating and therapeutic efficacy of chosen combinations of oximes with individual oximes against VX in rats and mice.
Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Brain; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Combinations; Lethal Dose 50; Male; Mice; Organothiophosphorus Compounds; Oximes; Pyridinium Compounds; Rats; Rats, Wistar; Trimedoxime | 2011 |
Human plasma-derived BuChE as a stoichiometric bioscavenger for treatment of nerve agent poisoning.
Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Butyrylcholinesterase; Chemical Warfare Agents; Cholinesterase Reactivators; Diazepam; Guinea Pigs; Humans; Injections, Intramuscular; Male; Organophosphate Poisoning; Organothiophosphorus Compounds; Oximes; Pyridinium Compounds | 2013 |
The potential role of bioscavenger in the medical management of nerve-agent poisoned casualties.
Topics: Animals; Atropine; Butyrylcholinesterase; Chemical Warfare Agents; Cholinesterase Reactivators; First Aid; Guinea Pigs; Humans; Military Medicine; Nerve Agents; Organophosphate Poisoning; Organothiophosphorus Compounds | 2016 |
Toxicity and median effective doses of oxime therapies against percutaneous organophosphorus pesticide and nerve agent challenges in the Hartley guinea pig.
Topics: Animals; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Dose-Response Relationship, Drug; Guinea Pigs; Lethal Dose 50; Male; Muscarinic Antagonists; Obidoxime Chloride; Organophosphate Poisoning; Organothiophosphorus Compounds; Oximes; Pesticides; Pralidoxime Compounds; Pyridinium Compounds; Time Factors | 2016 |
Optimization of the Ocular Treatment Following Organophosphate Nerve Agent Insult.
Topics: Animals; Antidotes; Atropine; Eye; Male; Miosis; Nerve Agents; Organothiophosphorus Compounds; Pupil; Rats; Rats, Long-Evans; Sarin; Tropanes; Vision, Ocular | 2017 |
The efficacy of HI-6 DMS in a sustained infusion against percutaneous VX poisoning in the guinea-pig.
Topics: Acetylcholinesterase; Animals; Atropine; Chemical Warfare Agents; Cholinesterase Reactivators; Dose-Response Relationship, Drug; Guinea Pigs; Infusions, Intravenous; Male; Muscarinic Antagonists; Nerve Agents; Organothiophosphorus Compounds; Oximes; Pyridinium Compounds; Survival Analysis | 2018 |
Bioscavenger is effective as a delayed therapeutic intervention following percutaneous VX poisoning in the guinea-pig.
Topics: Administration, Cutaneous; Animals; Antidotes; Atropine; Butyrylcholinesterase; Chemical Warfare Agents; Cholinesterase Reactivators; Cholinesterases; Dipeptides; Guinea Pigs; Male; Muscarinic Antagonists; Nerve Agents; Organothiophosphorus Compounds; Oximes; Pyridinium Compounds; Time-to-Treatment; Toxicokinetics | 2018 |
Repetitive antidotal treatment is crucial in eliminating eye pathology, respiratory toxicity and death following whole-body VX vapor exposure in freely moving rats.
Topics: Animals; Antidotes; Atropine; Benactyzine; Chemical Warfare Agents; Cholinesterase Inhibitors; Drug Administration Schedule; Drug Combinations; Environmental Exposure; Eye Diseases; Male; Obidoxime Chloride; Organothiophosphorus Compounds; Rats; Rats, Sprague-Dawley; Respiratory Tract Diseases; Trimedoxime | 2019 |
Pharmacokinetics and efficacy of atropine sulfate/obidoxime chloride co-formulation against VX in a guinea pig model.
Topics: Acetylcholinesterase; Animals; Atropine; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Disease Models, Animal; Drug Combinations; Guinea Pigs; Male; Muscarinic Antagonists; Obidoxime Chloride; Organothiophosphorus Compounds; Treatment Outcome | 2021 |
Efficacy of atropine and scopolamine on airway contractions following exposure to the nerve agent VX.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Atropine; Cholinergic Fibers; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Electric Stimulation; Female; GPI-Linked Proteins; Lung; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Organothiophosphorus Compounds; Rats, Sprague-Dawley; Scopolamine | 2021 |
A delayed treatment model for the evaluation of scopolamine for VX nerve agent intoxication.
Topics: Animals; Atropine; Chemical Warfare Agents; Cholinergic Antagonists; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Therapy, Combination; Guinea Pigs; Male; Midazolam; Nerve Agents; Organothiophosphorus Compounds; Pralidoxime Compounds; Scopolamine; Survival Rate; Time-to-Treatment | 2021 |
Pharmacological prophylaxis with pyridostigmine bromide against nerve agents adversely impact on airway function in an
Topics: Animals; Atropine; Cholinesterase Inhibitors; Lung; Nerve Agents; Pyridostigmine Bromide; Rats | 2023 |