Page last updated: 2024-09-05

atropine and vinblastine

atropine has been researched along with vinblastine in 10 studies

Compound Research Comparison

Studies (atropine)	Trials (atropine)	Recent Studies (post-2010) (atropine)	Studies (vinblastine)	Trials (vinblastine)	Recent Studies (post-2010) (vinblastine)
26,711	1,259	1,697	243	0	77

Protein Interaction Comparison

Protein	Taxonomy	vinblastine (IC50)
Tubulin alpha-1A chain	Sus scrofa (pig)	1.1
Tubulin beta chain	Sus scrofa (pig)	1.1
Tubulin beta-4A chain	Homo sapiens (human)	0.8233
Cholinesterase	Homo sapiens (human)	2.1
ATP-dependent translocase ABCB1	Mus musculus (house mouse)	8
Tubulin beta chain	Homo sapiens (human)	0.8233
ATP-dependent translocase ABCB1	Homo sapiens (human)	6
Tubulin alpha-3C chain	Homo sapiens (human)	0.8233
Cytochrome P450 2D6	Homo sapiens (human)	0.6
Polyunsaturated fatty acid lipoxygenase ALOX15	Oryctolagus cuniculus (rabbit)	5.037
Alpha-2B adrenergic receptor	Rattus norvegicus (Norway rat)	2.1
Alpha-2C adrenergic receptor	Rattus norvegicus (Norway rat)	2.1
Alpha-2A adrenergic receptor	Rattus norvegicus (Norway rat)	2.1
Thromboxane-A synthase	Homo sapiens (human)	1.87
Tubulin alpha-1B chain	Homo sapiens (human)	0.8233
Tubulin alpha-4A chain	Homo sapiens (human)	0.8233
Tubulin beta-4B chain	Homo sapiens (human)	0.8233
Tubulin beta-3 chain	Homo sapiens (human)	0.8233
Tubulin beta-2A chain	Homo sapiens (human)	0.8233
Beta-tubulin	Leishmania donovani	1
Tubulin beta-8 chain	Homo sapiens (human)	0.8233
Tubulin beta-2B chain	Bos taurus (cattle)	0.65
Tubulin alpha-3E chain	Homo sapiens (human)	0.8233
Tubulin alpha-1A chain	Homo sapiens (human)	0.8233
Similar to alpha-tubulin isoform 1	Bos taurus (cattle)	0.65
Similar to alpha-tubulin isoform 1	Bos taurus (cattle)	0.65
Tubulin alpha-1C chain	Homo sapiens (human)	0.8233
Tubulin beta-6 chain	Homo sapiens (human)	0.8233
Tubulin beta-2B chain	Homo sapiens (human)	0.8233
Tubulin beta-1 chain	Homo sapiens (human)	0.8233

Research

Studies (10)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	6 (60.00)	29.6817
2010's	4 (40.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Glen, RC; Lowe, R; Mitchell, JB	1
Bracke, ME; De Ryck, T; Katritzky, AR; Patronov, A; Roman, BI; Slavov, SH; Stevens, CV; Vanhoecke, BW	1

Other Studies

10 other study(ies) available for atropine and vinblastine

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
4-Fluoro-3',4',5'-trimethoxychalcone as a new anti-invasive agent. From discovery to initial validation in an in vivo metastasis model. European journal of medicinal chemistry, 2015, Aug-28, Volume: 101 Topics: Animals; Antineoplastic Agents, Phytogenic; Biological Products; Cell Line, Tumor; Cell Movement; Cell Survival; Chalcones; Chick Embryo; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Discovery; Female; Humans; Mice; Mice, Nude; Molecular Structure; Myocardium; Neoplasm Invasiveness; Neoplasm Metastasis; Quantitative Structure-Activity Relationship	2015