atropine has been researched along with verapamil in 222 studies
| Studies (atropine) | Trials (atropine) | Recent Studies (post-2010) (atropine) | Studies (verapamil) | Trials (verapamil) | Recent Studies (post-2010) (verapamil) |
|---|---|---|---|---|---|
| 26,711 | 1,259 | 1,697 | 17,621 | 1,527 | 2,067 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 111 (50.00) | 18.7374 |
| 1990's | 54 (24.32) | 18.2507 |
| 2000's | 32 (14.41) | 29.6817 |
| 2010's | 24 (10.81) | 24.3611 |
| 2020's | 1 (0.45) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Lüllmann, H; Timmermans, PB; Weikert, GM; Ziegler, A | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Aimi, N; Horie, S; Ishikawa, H; Kitajima, M; Koyama, F; Kurihara, M; Matsumoto, K; Moriyama, T; Murayama, T; Ponglux, D; Takayama, H; Watanabe, K; Yamamoto, LT | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Bard, B; Carrupt, PA; Martel, S | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Chiba, S | 3 |
| Murao, S; Uchida, Y; Yoshimoto, N | 1 |
| Antonini, L; Disertori, M; Furlanello, F; Lanzetta, T; Molinis, G | 1 |
| Januskevicius, ZI; Zabela, PV; Zemaityte, DI | 1 |
| Landmark, K; Storstein, O | 1 |
| Hansen, JF; Sandøe, E | 1 |
| Satoh, K; Taira, N; Yanagisawa, T | 1 |
| Demling, L; Domschke, S; Domschke, W; Mitznegg, P; Schubert, E; Strunz, U | 1 |
| Vanhoutte, PM; Vermeire, PA | 1 |
| Leavitt, L; Mukhopadhyay, AK | 1 |
| Collis, MG; Shepherd, JT | 1 |
| Arndts, D | 1 |
| Csapo, G | 1 |
| Khalsa, A; Olsson, SB | 1 |
| Kajitsuka, T | 1 |
| Bressan, M; Buja, GF; De Petris, A; Ferrari, M; Marinato, PG; Melacini, P; Nava, A; Prandi, AM | 1 |
| Huang, TF | 1 |
| Barboza, JS; Carrasco, HA; Fuenmayor, A; Gonzalez, G | 1 |
| Hasl, G; Heim, F; Mitznegg, P; Pauly, H; Schubert, E; Sprügel, W | 1 |
| Ohkawa, H; Watanabe, M | 1 |
| Beitzke, A; Grubbauer, HM | 1 |
| Lefebvre, PJ; Luyckx, AS | 1 |
| Demling, L; Domschke, S; Domschke, W; Jaeger, E; Mitznegg, P; Schubert, E; Strunz, U; Wünsch, E | 1 |
| Ninomiya, JG | 1 |
| Kuriyama, H; Suzuki, H | 1 |
| Konishi, T | 1 |
| Ekström, B | 1 |
| Allmann, DW; Behforouz, H; Chikada, K; DePaoli-Roach, A; Dominianni, SJ; Harris, RA; Scislowski, P; Stephens, TW; Yamanouchi, K | 1 |
| Edmiston, CE; Frantzides, CT; Greenwood, B; Lianos, EA; Wittmann, D | 1 |
| Calignano, A; Capasso, A; Mancuso, F; Persico, P; Sorrentino, L | 1 |
| Grupp, G; Grupp, I; Heikkila, J; Luomanmaki, K; Pesola, MK; Ramo, MP; Schroder, T | 1 |
| Fuente, MP; Mellado, F; Salinas, J; Uson, AC; Virseda, M | 2 |
| Franz, DR; Robinson, CP | 1 |
| Pillai, G; Sutter, MC | 1 |
| Crevel, H; Marthan, R; Savineau, JP | 1 |
| Kelly, E; Leff, AR; Mitchell, RW; Murphy, TM | 1 |
| Ishizawa, M | 1 |
| Barringer, DL; Buñag, RD | 1 |
| Bowyer, JF; Weiner, N | 1 |
| Chang, PL; Dixon, WR | 1 |
| Fich, A; Hanson, RB; Neri, M; Phillips, SF; Zinsmeister, AR | 1 |
| Diener, M; Döring, A; Rummel, W | 1 |
| Avenant, JC; Meyer, EC; Sommers, DK | 1 |
| Rahwan, RG; Stephens, RL; Wong, WS | 1 |
| Kodama, I; Kondo, N; Kotake, H; Shibata, S | 1 |
| Kindle, H; Kunkel, JG; Lanzrein, B | 1 |
| Uematsu, T; Yamaguchi, M | 1 |
| Münnich, R; Ziesenhenn, K | 1 |
| Clementi, F; Gotti, C; Madeddu, L; Pandiella, A; Sher, E | 1 |
| Choo, LK; Gardner, AL; Mitchelson, F | 1 |
| Dharmsathaphorn, K; Donowitz, M; Mikkelsen, R; Reinlib, L; Zahniser, D | 1 |
| Rodger, IW; Shahid, M | 1 |
| Benedetti, M; Frank, C; Sagratella, S; Scotti de Carolis, A | 1 |
| Aoki, K; Kishimoto, T; Naruchi, T; Okamiya, Y; Takeshita, T | 1 |
| Mehmel, HC | 1 |
| Chang, CC; Hong, SJ | 1 |
| Matthijs, G; Peeters, TL; Vantrappen, G | 1 |
| Alfredson, ML; Armour, CL; Black, JL; Johnson, PR | 1 |
| Asano, M | 1 |
| Dandona, P; Jeremy, JY | 1 |
| Bettini, V; Catozzo, C; Martino, R; Mayellaro, F; Munari, L; Tegazzin, V; Ton, P | 1 |
| Dandona, P; Jeremy, JY; Mikhailidis, DP | 1 |
| Cho, CH; Koo, MW; Ogle, CW | 1 |
| Harish, OE; Kao, LS; Raffaniello, R; Schneider, AS; Wakade, AR | 1 |
| Barragry, TP; Blatchford, JW; Ring, WS; Tuna, IC | 1 |
| Hubel, KA; Renquist, KS | 1 |
| Dawson, AP; Hill, CE; Olson, MS; Pryor, JS | 1 |
| Ke, J; Liu, YB; Weng, SA | 1 |
| Kremer Hovinga, TK; ter Wee, PM; Uges, DR; van der Geest, S | 1 |
| Cheng, H; Cohen, P; Donowitz, M; Elta, G; Levin, S; Powers, G | 1 |
| Gilmour, RF; Zipes, DP | 1 |
| Boyd, AE; Field, JB; Sheela Rani, CS | 1 |
| Dunlop, ME; Malaisse, WJ | 1 |
| Cusolito, S; Donowitz, M; Sharp, GW | 1 |
| Algeo, S; Gay, R; Goldman, S; Lee, R; Morkin, E; Olajos, M | 1 |
| Best, L; Malaisse, WJ; Mathias, PC | 1 |
| Chiba, S; Horiuchi, A; Iwatsuki, K; Yamagishi, F | 1 |
| Koley, BN; Koley, J; Saha, JK | 1 |
| Burgess, CD; Warrington, SJ; Weerasuriya, K | 1 |
| Chow, R; Nebitko, RL; Zsotér, TT | 1 |
| Ito, Y; Kuriyama, H; Parker, I | 1 |
| Herman, CA; Robleto, DO | 1 |
| McCormick, JP; Russell, JA | 1 |
| Duncan, R; Krzanowski, J; Lockey, R; Martin, DF; Nelson, R; Polson, J; Shimoda, T | 1 |
| Barragry, TP; Benditt, DG; Blatchford, JW; Bolman, RM; Gornick, CC; Qi, AZ; Ring, WS; Tuna, IC; Walker, MJ | 1 |
| Ishii, T; Shimo, Y | 1 |
| Duncan, R; Krzanowski, J; Lockey, R; Martin, DF; Perez-Cruet, M; Polson, J; Shimoda, T | 1 |
| Dreifus, LS; Mazgalev, T; Michelson, EL; Mitamura, H; Mitsuoka, T; Pelleg, A | 1 |
| Molyvdas, PA; Sperelakis, N | 1 |
| Augsten, G; Pfeiffer, D; Rathgen, K; Rostock, KJ | 1 |
| Alya, G; Feletou, M; Tricoche, R; Walden, M | 1 |
| Kornegay, ET; Lee, JC; McGrath, CJ | 1 |
| Bowes, KL; Gill, RC; Kingma, YJ | 1 |
| Brandt, HD; Bunn, AE; Krivoy, N | 2 |
| Ingenito, AJ | 1 |
| Diedrich, R; Hardewig, A | 1 |
| Beich, W; Gref, H; Ising, H; Lunkenheimer, PP; Muchow, S; Noack, W | 1 |
| Bender, F | 1 |
| Chazov, EI | 1 |
| Holmberg, S; Husaini, MH; Kvasnicka, J; Ryèn, L | 1 |
| Filias, N | 1 |
| Fischer, JC; Zipes, DP | 1 |
| Bass, O; Friedemann, M | 1 |
| Ehara, T; Mitsuiye, T | 1 |
| MacAlpin, R | 1 |
| Hirai, M; Komoriyama, K; Kouyama, H; Shima, S | 1 |
| Belhassen, B; Laniado, S; Paredes, A; Pelleg, A | 1 |
| Nilius, B | 1 |
| Aomine, M; Arita, M; Imanishi, S; Kiyosue, T | 1 |
| Abe, M; Furukawa, T | 1 |
| Maggi, CA; Meli, A | 2 |
| Taira, N; Yanagisawa, T | 1 |
| Dohi, T; Kitayama, S; Morita, K; Tsujimoto, A | 1 |
| Mitchelson, F; Ziegler, A | 1 |
| Brunori, P; D'Agostino, G; Grana, E; Santagostino Barbone, MG; Subissi, A; Zonta, F | 1 |
| Kometani, A; Nakajyo, S; Ozaki, H; Shimizu, K; Suzuki, A; Urakawa, N | 1 |
| Bertrix, L; Bouzouita, K; Faucon, G; Lakhal, M; Lang, J; Timour-Chah, Q | 1 |
| Yasue, H | 1 |
| Ochillo, RF; Tsai, CS | 1 |
| Millard, RW; Nakaya, H; Schwartz, A | 1 |
| Postius, S; Szelenyi, I | 1 |
| Gloor, HO; Urthaler, F | 1 |
| Grimaldi, G; Maggi, CA; Meli, A | 1 |
| Bettini, R; Dal Forno, P; Disertori, M; Furlanello, F; Inama, G; Stefenelli, C; Vergara, G; Zuechi, S | 1 |
| Chiba, S; Furukawa, Y | 1 |
| Mendel, D | 1 |
| Bressan, M; Buja, GF; Dalla Volta, S; Marinato, PG; Melacini, P; Nava, A | 1 |
| Mao, H; Wong, LB | 1 |
| Boucher, M; Chapuy, E; Chassaing, C; Duchêne-Marullaz, P | 1 |
| Diamant, NE; Preiksaitis, HG | 1 |
| Chen, YH; Tsai, MC | 1 |
| Igbo, IN; Onuaguluchi, G | 1 |
| Capili, H; Garcia, J; Schwartz, JB; Shen, C; Sniezek, M | 1 |
| Guieu, R; Rochat, H; Rosso, JP | 1 |
| Calabrese, P; Massari, V; Tricarico, G; Tritto, M | 1 |
| Chen, JM; Gu, SL; Zhang, GY; Zhang, MZ | 1 |
| Ferrara, JJ; Flint, LM; Force, SD; Franklin, EW; Hyman, AL; Lippton, HL; Taheri, PA | 1 |
| Chayvialle, JA; Cuber, JC; Dakka, T; Dumoulin, V | 1 |
| Arakawa, K; Benson, KT; Goto, H; Oshida, J | 1 |
| Levin, RM; Wein, AJ; Zhao, Y | 1 |
| Borys, D; Ramoska, EA; Spiller, HA; Winter, M | 1 |
| Eichler, HG; Kastner, J; Krejcy, K; Schmetterer, L; Unfried, C; Wolzt, M; Zanaschka, G | 1 |
| Kitazawa, T; Ohga, A; Taneike, T | 1 |
| Eichler, HG; Gouya, G; Schmetterer, L; Wolzt, M; Zanaschka, G | 1 |
| Buck, MG; Goswami, S; Maayani, S; Marom, Z; Rienzi, N; Schachter, EN; Zuskin, E | 1 |
| Wong, KK | 1 |
| Brown, DR; Malone, ED; Trent, AM; Turner, TA | 1 |
| Antunes, E; Brain, SD; Costa, SK; De Nucci, G; Moreno, H | 1 |
| Kasabdji, D; Rathinavelu, A; Shanmugam, V | 1 |
| Sheng, JZ; Wang, HX; Wong, TM; Zhang, WM | 1 |
| Kato, S; Takehara, K; Takeuchi, K; Yagi, K | 1 |
| Carvajal, A; Dueñas, A; Fernández de la Gándara, F; Maroto, M; Nieto, A; Velasco, A | 1 |
| Hussein, AA; Nabil, ZI; Rakha, MKh; Zalat, SM | 1 |
| Ellenbogen, KA; Gilligan, DM; Natale, A; Shepard, RK; Stambler, BS; Wood, MA | 1 |
| Gaertner, LS; Morris, CE; Murray, CL | 1 |
| Kaneko, S; Nakano, D; Nishimori, T; Ohara, M | 1 |
| Ito, Y; Yamaki, K | 1 |
| Baistrocchi, RL; de los Santos, AR; Di Girolamo, G; Marti, ML; Orti, E; Pico, JC | 1 |
| Chiba, S; Furukawa, Y; Hirose, M; Kurogouchi, F; Nakajima, K; Tsuboi, M; Zhao, D | 1 |
| Verheye, S; Vermeersch, P | 1 |
| Adnet, F; Baud, F; Benaissa, A; Bourdain, F; Lapostolle, F; Muszynski, J | 1 |
| Lei, Z; Liu, Z; Ni, J; Wu, R; Ye, M; Zou, H | 1 |
| Abo-Ghalia, AH; Elbanna, S; Nabil, ZI; Zalat, S | 1 |
| Hong, C; Ishikawa, Y; Kawabe, J; Lee, MC; Liu, J; Okumura, S; Sadoshima, J; Takagi, G; Takagi, I; Vatner, DE; Vatner, SF; Yatani, A | 1 |
| Katerere, D; Parry, O | 1 |
| Borrelli, F; Capasso, F; Capasso, R; Izzo, AA; Mascolo, N | 1 |
| Li, W; Luo, YL; Qu, SY; Wei, YL; Yu, M; Zeng, JW; Zheng, TZ | 1 |
| Chen, JD; Hou, X; Liu, J; Pasricha, PJ; Yin, J | 1 |
| Chiung, YM; Kao, YY; Liu, PS | 1 |
| Dkhar, SA; Naveen, AT; Peddyreddy, MK; Ramaswamy, S; Shewade, DG | 1 |
| Cao, LH; Choi, DH; Kang, DG; Kim, JS; Kim, SJ; Lee, H; Lee, HS; Lee, JK | 1 |
| Sarna, SK | 1 |
| Daenas, C; Gourgoulianis, KI; Hatziefthimiou, AA; Molyvdas, PA | 1 |
| Itoh, Z; Koga, H; Omura, S; Ozaki, K; Takanashi, H; Yogo, K | 1 |
| Bania, TC; Chu, J; Hahn, IH; Perez, E; Su, M | 1 |
| Akino, H; Aoki, Y; Ito, H; Miwa, Y; Oyama, N; Yokoyama, O | 1 |
| Agbedahunsi, JM; Ahmed, T; Choudhary, MI; Ghayur, MN; Gilani, AH; Houghton, PJ; Khalid, A; Nawaz, SA | 1 |
| Reanmongkol, W; Subhadhirasakul, S; Thaina, P; Tungcharoen, P; Wongnawa, M | 1 |
| Gilani, AH; Shah, AJ | 2 |
| Bourgeois, M; Richards, IS | 1 |
| Bafor, EE; Nworgu, ZA; Sanni, U | 1 |
| Chang, CC; Ho, JD; Huang, KH; Lu, RH; Tsai, LH | 1 |
| Ahmad, B; Ali, N; Shah, SW | 1 |
| Gao, WY; Hu, J; Huang, LQ; Liu, CX; Ma, L; Man, SL | 1 |
| Büyüknacar, HS; de Groat, WC; Ertuğ, PU; Eser, N; Göçmen, C; Kumcu, EK; Onder, S | 1 |
| Ahmed, G; Ali Shah, SW; Ali, N; Ali, W; Ghias, M; Khan, I; Shah, I | 1 |
| Khan, AU; Murugan, DD; Mustafa, MR | 1 |
| Fu, Q; Huang, YJ; Jiang, SZ; Lu, W; Wang, HB; Wang, LG; Wang, YJ; Wu, Q | 1 |
| Chen, DP; Lin, Y; Liu, FF; Lv, BC; Tang, ZY; Wang, L; Xiong, YJ | 1 |
| Connolly, K; Coulson, FR; Fenning, AS; Hill, N; Yesmine, S | 1 |
| Chen, DP; Lin, Y; Liu, FF; Lv, BC; Wang, L; Xiong, YJ | 1 |
| Chen, DP; Diao, YP; Lin, Y; Yao, QY; Ye, DM | 1 |
| Nanri, M; Sakakibara, F; Sasaki, E; Takahama, K | 1 |
| Jolobe, OMP | 1 |
5 review(s) available for atropine and verapamil
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Treatment of arrhythmia in myocardial infarct].
Topics: Amides; Arrhythmias, Cardiac; Atrial Fibrillation; Atropine; Cardiac Complexes, Premature; Cardiac Glycosides; Glucose; Humans; Injections, Intramuscular; Injections, Intravenous; Insulin; Myocardial Infarction; Phytotherapy; Plants, Medicinal; Potassium; Prednisolone; Procaine; Propranolol; Pyridoxine; Rauwolfia; Strophanthins; Sympathomimetics; Tachycardia, Paroxysmal; Thiamine; Thiamine Pyrophosphate; Ventricular Fibrillation; Verapamil; Water-Electrolyte Balance | 1968 |
Treatment of vasospastic angina.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Anemia; Angina Pectoris, Variant; Atropine; Diltiazem; Drug Therapy, Combination; Epoprostenol; Exercise Therapy; Female; Humans; Hypertension; Hyperthyroidism; Isosorbide Dinitrate; Male; Middle Aged; Nifedipine; Nitroglycerin; Nitroprusside; Nylidrin; Verapamil | 1983 |
[Progress in arrhythmology].
Topics: Adolescent; Adult; Aged; Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Cardiac Pacing, Artificial; Child; Electrocardiography; Exercise Test; Heart Conduction System; Humans; Middle Aged; Propafenone; Propiophenones; Sick Sinus Syndrome; Stimulation, Chemical; Verapamil; Wolff-Parkinson-White Syndrome | 1981 |
Intra-atrial and atrioventricular nodal reentrant tachycardia in the same subject diagnosed at transesophageal electrophysiologic study.
Topics: Adult; Atropine; Cardiac Pacing, Artificial; Electrocardiography; Esophagus; Female; Humans; Tachycardia, Atrioventricular Nodal Reentry; Tachycardia, Ectopic Atrial; Verapamil | 1994 |
3 trial(s) available for atropine and verapamil
| Article | Year |
|---|---|
Atropine and verapamil interactions in healthy volunteers.
Topics: Adult; Atropine; Depression, Chemical; Drug Interactions; Heart Rate; Humans; Male; Pirenzepine; Single-Blind Method; Stimulation, Chemical; Verapamil | 1991 |
Short-term drug effects on the signal-averaged electrocardiogram in healthy men: assessment of intra- and interindividual variability of spectral temporal mapping and time-domain analysis.
Topics: Adenosine; Adult; Atropine; Cardiovascular Agents; Cross-Over Studies; Electrocardiography; Heart; Hemodynamics; Humans; Isoproterenol; Lidocaine; Male; Norepinephrine; Placebos; Propranolol; Reference Values; Reproducibility of Results; Time Factors; Verapamil | 1995 |
Is the ECG measure RSh a promising technique for detecting class I antiarrhythmic drug action in men?
Topics: Adenosine; Adult; Ajmaline; Anti-Arrhythmia Agents; Atropine; Disopyramide; Electrocardiography; Humans; Injections, Intravenous; Isoproterenol; Male; Norepinephrine; Propranolol; Reproducibility of Results; Sodium Channel Blockers; Verapamil | 1995 |
214 other study(ies) available for atropine and verapamil
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Accumulation of drugs by guinea pig isolated atria. Quantitative correlations.
Topics: Animals; Chemistry, Pharmaceutical; Electric Stimulation; Guinea Pigs; Humans; In Vitro Techniques; Kinetics; Myocardium; Pharmaceutical Preparations; Protein Binding; Serum Albumin; Solubility; Time Factors | 1980 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Studies on the synthesis and opioid agonistic activities of mitragynine-related indole alkaloids: discovery of opioid agonists structurally different from other opioid ligands.
Topics: Analgesics; Animals; Brain; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Indole Alkaloids; Ligands; Mice; Models, Molecular; Morphine; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Secologanin Tryptamine Alkaloids; Structure-Activity Relationship | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Lipophilicity of basic drugs measured by hydrophilic interaction chromatography.
Topics: Chemistry, Pharmaceutical; Chromatography; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pharmaceutical Preparations; Solubility; Technology, Pharmaceutical | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Pharmacologic analysis of stretch-induced sinus acceleration of the isolated dog atrium.
Topics: Adrenergic beta-Antagonists; Animals; Atrial Function; Atropine; Dogs; Heart Rate; Norepinephrine; Physical Stimulation; Propranolol; Sinoatrial Node; Tetrodotoxin; Time Factors; Verapamil | 1977 |
Effects of anti-anginal agents on cyclical reductions of coronary blood flow.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Blood Pressure; Coronary Circulation; Diltiazem; Dipyridamole; Dogs; Electrocardiography; Injections, Intravenous; Niacinamide; Nicotinic Acids; Nifedipine; Nitrates; Nitroglycerin; Papaverine; Periodicity; Phentolamine; Propranolol; Vasodilator Agents; Verapamil | 1978 |
[Effects of verapamil on sinusal function and on atrioventricular conduction along normal and abnormal pathways, in patients with pre-existing troubles of excitation conduction (author's transl)].
Topics: Adult; Aged; Arrhythmias, Cardiac; Atrioventricular Node; Atropine; Bundle of His; Cardiac Complexes, Premature; Electrocardiography; Female; Heart Conduction System; Humans; Male; Middle Aged; Tachycardia, Paroxysmal; Verapamil; Wolff-Parkinson-White Syndrome | 1976 |
[Various aspects of individualization of drug therapy of extrasystole].
Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Atropine; Belladonna Alkaloids; Cardiac Complexes, Premature; Drug Evaluation; Drug Therapy, Combination; Humans; Injections, Intravenous; Middle Aged; Oxprenolol; Potassium Magnesium Aspartate; Procainamide; Propranolol; Quinidine; Strophanthins; Verapamil | 1977 |
Ectopic atrial tachycardia on swallowing. Report on favourable effect of verapamil.
Topics: Atrioventricular Node; Atropine; Cardiac Complexes, Premature; Deglutition; Disopyramide; Edrophonium; Electrocardiography; Female; Heart Atria; Heart Block; Hernia, Diaphragmatic; Hernia, Hiatal; Humans; Middle Aged; Practolol; Tachycardia; Verapamil | 1979 |
Treatment of Prinzmetal's angina due to coronary artery spasm using verapamil: a report of three cases.
Topics: Angina Pectoris; Angina Pectoris, Variant; Atropine; Coronary Disease; Electrocardiography; Heart Block; Humans; Male; Middle Aged; Nitroglycerin; Spasm; Verapamil | 1978 |
Circumstantial evidence for increased potassium conductance of membrane of cardiac muscle by 2-nicotinamidoethyl nitrate (SG-75).
Topics: Animals; Atropine; Depression, Chemical; Dogs; Female; In Vitro Techniques; Male; Membrane Potentials; Methacholine Compounds; Myocardial Contraction; Niacinamide; Nicorandil; Nitrates; Papillary Muscles; Perfusion; Potassium; Refractory Period, Electrophysiological; Ventricular Fibrillation; Verapamil | 1979 |
[The mode of action of bisacodyl on the smooth muscle of the small and the large intestine of the guinea pig].
Topics: Acetylcholine; Animals; Atropine; Bisacodyl; Calcium; Colon; Cresols; Cyclic AMP; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histamine; Ileum; Male; Muscle Contraction; Muscle, Smooth; Peristalsis; Pheniramine; Verapamil | 1975 |
Inhibition by catecholamines of cholinergic neurotransmission in canine bronchi in vitro.
Topics: Animals; Atropine; Bronchi; Catecholamines; Depression, Chemical; Dogs; Hexamethonium Compounds; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth; Norepinephrine; Parasympathetic Nervous System; Phentolamine; Propranolol; Synaptic Transmission; Terbutaline; Tetrodotoxin; Verapamil | 1977 |
Evidence for an angiotensin receptor in esophageal smooth muscle of the opossum.
Topics: Angiotensin Amide; Angiotensin II; Animals; Atropine; Dose-Response Relationship, Drug; Esophagogastric Junction; Female; Hexamethonium Compounds; Male; Nicotine; Phentolamine; Phenylephrine; Receptors, Angiotensin; Receptors, Cell Surface; Saralasin; Tetrodotoxin; Vagus Nerve; Verapamil | 1978 |
Isoproterenol-induced relaxation of venous smooth muscle contracted by agents which mobilize different calcium pools.
Topics: Acetylcholine; Animals; Atropine; Blood Vessels; Calcium; Dogs; Drug Interactions; In Vitro Techniques; Isoproterenol; Norepinephrine; Phenylephrine; Potassium; Propranolol; Receptors, Adrenergic, beta; Receptors, Muscarinic; Vasoconstriction; Vasodilation; Verapamil | 1979 |
Drug effects on myocardial 45Ca uptake in conscious rats.
Topics: Adrenergic beta-Antagonists; Aminophylline; Animals; Atropine; Bucladesine; Calcium; Dose-Response Relationship, Drug; Drug Interactions; Epinephrine; Extracellular Space; Isoproterenol; Male; Myocardium; Norepinephrine; Phentolamine; Propanolamines; Rats; Sympathomimetics; Time Factors; Verapamil | 1975 |
Paroxysmal nonreentrant tachycardias due to simultaneous conduction in dual atrioventricular nodal pathways.
Topics: Adult; Ajmaline; Atrial Fibrillation; Atrioventricular Node; Atropine; Bundle of His; Cardiac Pacing, Artificial; Electrocardiography; Heart Block; Heart Conduction System; Humans; Lidocaine; Male; Metoprolol; Models, Biological; Tachycardia, Paroxysmal; Verapamil | 1979 |
Verapamil-induced ventricular regularity in atrial fibrillation. Effects of exercise, isoproterenol, atropine and conversion to sinus rhythm.
Topics: Adult; Aged; Atrial Fibrillation; Atropine; Electrocardiography; Exercise Test; Female; Heart Rate; Heart Ventricles; Humans; Isoproterenol; Male; Middle Aged; Physical Exertion; Verapamil | 1979 |
Phasic and tonic contractions of rabbit intestinal muscle.
Topics: Animals; Atropine; Cocaine; Electric Stimulation; In Vitro Techniques; Intestine, Small; Muscle Contraction; Muscle Tonus; Nitroprusside; Rabbits; Tetrodotoxin; Verapamil | 1979 |
[Approach to the pharmacological study of the various structures of the A-V node].
Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Atrioventricular Node; Atropine; Electric Stimulation; Electrophysiology; Female; Heart Conduction System; Humans; Male; Middle Aged; Refractory Period, Electrophysiological; Time Factors; Verapamil | 1979 |
Cardiac arrhythmia induced by electrical stimulation of the fastigial nucleus in cats.
Topics: Animals; Arrhythmias, Cardiac; Atropine; Cats; Cerebellar Nuclei; Electric Stimulation; Female; Hypothalamus, Posterior; Male; Pressoreceptors; Propranolol; Tetrodotoxin; Verapamil | 1977 |
Effect of verapamil on normal sinoatrial node function and on sick sinus syndrome.
Topics: Adult; Aged; Arrhythmia, Sinus; Atropine; Cardiac Pacing, Artificial; Dose-Response Relationship, Drug; Female; Humans; Isoproterenol; Male; Middle Aged; Propranolol; Sinoatrial Node; Verapamil | 1978 |
Immediate X-radiation induced contractions of the isolated guinea pig terminal ileum: the localization of the effect by drugs.
Topics: Acetylcholine; Animals; Atropine; Diphenhydramine; Female; Guinea Pigs; Hexamethonium Compounds; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Nicotine; Tetrodotoxin; Time Factors; Verapamil; X-Rays | 1977 |
Effects of gastrointestinal hormones on the electrical and mechanical activity of the cat stomach.
Topics: Action Potentials; Animals; Atropine; Caffeine; Cats; Cholecystokinin; Gastrins; Gastrointestinal Hormones; Imidazoles; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Pyloric Antrum; Secretin; Stomach; Tetrodotoxin; Theophylline; Verapamil | 1977 |
[Isoptin (verapamil) poisoning].
Topics: Atropine; Child, Preschool; Digitalis Glycosides; Female; Humans; Metaproterenol; Prenylamine; Respiration, Artificial; Verapamil | 1976 |
Different chronotropic and inotropic effects of pentobarbital in the blood-perfused, isolated dog atrium.
Topics: Animals; Atropine; Dogs; Heart; Heart Atria; Heart Rate; Manganese; Norepinephrine; Pentobarbital; Time Factors; Verapamil | 1976 |
Effect of pentobarbital, verapamil and manganese on the frequency-force relationship of the isolated atrium and ventricle of the dog heart.
Topics: Animals; Atropine; Dogs; Electric Stimulation; Female; Heart; Heart Rate; In Vitro Techniques; Male; Manganese; Myocardial Contraction; Pentobarbital; Propranolol; Verapamil | 1976 |
Pharmacological compounds affecting plasma glucagon levels in rats.
Topics: Animals; Atropine; Blood Glucose; Depression, Chemical; Fatty Acids, Nonesterified; Glucagon; Insulin; Male; Nicotinic Acids; Physical Exertion; Procaine; Propranolol; Quinidine; Rats; Reserpine; Swimming; Verapamil | 1976 |
Analysis of the motor effects of 13-norleucine motilin on the rabbit, guinea pig, rat, and human alimentary tract in vitro.
Topics: Acetylcholine; Animals; Atropine; Calcium; Colon; Dose-Response Relationship, Drug; Female; Gallbladder; Gastrointestinal Hormones; Gastrointestinal Motility; Guinea Pigs; Hexamethonium Compounds; Histamine; Humans; In Vitro Techniques; Intestine, Small; Male; Muscle Contraction; Muscle, Smooth; Myometrium; Neural Pathways; Norleucine; Peptides; Pheniramine; Rabbits; Rats; Stomach; Vasomotor System; Verapamil | 1975 |
Some pharmacological properties of the cremaster muscle of the guinea-pig.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Electric Stimulation; Epinephrine; Guinea Pigs; Histamine; Hypertonic Solutions; In Vitro Techniques; Male; Muscle Contraction; Muscles; Phentolamine; Tetrodotoxin; Tubocurarine; Verapamil | 1975 |
Electrical and mechanical properties of longitudinal and circular muscles of the guinea-pig ileum.
Topics: Animals; Atropine; Caffeine; Guinea Pigs; Ileum; In Vitro Techniques; Lanthanum; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Procaine; Prostaglandins E; Tetrodotoxin; Verapamil | 1975 |
Electrophysiological consideration on sick sinus syndrome.
Topics: Acetylcholine; Action Potentials; Age Factors; Animals; Arrhythmia, Sinus; Atropine; Depression, Chemical; Heart Rate; In Vitro Techniques; Neostigmine; Rabbits; Sinoatrial Node; Verapamil | 1976 |
Intravesical instillation of drugs in patients with detrusor hyperactivity.
Topics: Administration, Intravesical; Animals; Atropine; Butylamines; Female; Humans; Parasympatholytics; Phentolamine; Rabbits; Urinary Bladder; Urinary Bladder, Neurogenic; Urodynamics; Verapamil | 1992 |
Metabolic effects of proglycosyn.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Atropine; Cells, Cultured; Cyclic AMP; Glucagon; Glycogen Synthase; Hypoglycemic Agents; Imidazoles; Kinetics; Liver; Liver Glycogen; Male; Phosphoprotein Phosphatases; Phosphorylase a; Rats; Rats, Inbred Strains; Verapamil | 1992 |
Prostaglandins and modulation of small bowel myoelectric activity.
Topics: Animals; Atropine; Dinoprost; Dinoprostone; Dogs; Electromyography; Gastrointestinal Motility; Hexamethonium; Hexamethonium Compounds; Intestine, Small; Male; Muscle, Smooth; Perfusion; Tetrodotoxin; Verapamil | 1992 |
Dexamethasone modifies morphine-, atropine-, verapamil-induced constipation in mice.
Topics: Animals; Atropine; Constipation; Dexamethasone; Dose-Response Relationship, Drug; Drug Interactions; Gastrointestinal Transit; Male; Mice; Morphine; Verapamil | 1992 |
Cardiac glycosides in the treatment of experimental overdose with calcium-blocking agents.
Topics: Animals; Atropine; Calcium; Calcium Channel Blockers; Calcium Gluconate; Depression, Chemical; Digoxin; Diltiazem; Dogs; Drug Overdose; Electrocardiography; Female; Hemodynamics; Humans; Male; Myocardium; Verapamil | 1992 |
A study on the viscoelastic properties of the urinary bladder in dogs.
Topics: Animals; Atropine; Biomechanical Phenomena; Dogs; Egtazic Acid; Elastic Tissue; Male; Models, Biological; Muscle, Smooth; Nitroprusside; Random Allocation; Urinary Bladder; Verapamil | 1992 |
Importance of the active component of the detrusor muscle in bladder compliance.
Topics: Animals; Atropine; Dogs; Egtazic Acid; Male; Muscle, Smooth; Nitroprusside; Urinary Bladder; Verapamil | 1992 |
Effects of palytoxin on guinea pig tracheal strips.
Topics: Acrylamides; Airway Resistance; Animals; Atropine; Calcium; Cnidarian Venoms; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Masoprocol; Muscle Contraction; Muscle, Smooth; Ouabain; Potassium; Pyrilamine; Sodium; Solutions; Trachea; Verapamil | 1991 |
Effect of human plasma proteins on spontaneous contractile activity of rat mesenteric portal vein.
Topics: Alpha-Globulins; Animals; Atropine; Beta-Globulins; Blood Proteins; Chlorpheniramine; gamma-Globulins; Humans; Immunoglobulin G; Ketanserin; Male; Mesenteric Veins; Muscle Contraction; Muscle, Smooth, Vascular; Ouabain; Phentolamine; Portal Vein; Rats; Rats, Inbred Strains; Saralasin; Serum Albumin; Verapamil | 1990 |
Contraction of vascular smooth muscle induced by phorbol 12,13 dibutyrate in human and rat pulmonary arteries.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Atropine; Calcium; Humans; In Vitro Techniques; Isometric Contraction; Muscle Contraction; Muscle Tonus; Muscle, Smooth, Vascular; Phentolamine; Phorbol 12,13-Dibutyrate; Potassium; Propranolol; Protein Kinase C; Pulmonary Artery; Rats; Tetrodotoxin; Trifluoperazine; Verapamil | 1991 |
Extracellular Ca2+ mobilization in potential-dependent contraction of trachealis of maturing swine.
Topics: Animals; Atropine; Calcium; Calcium Channel Blockers; Extracellular Space; Male; Muscle Contraction; Muscle, Smooth; Parasympathetic Nervous System; Parasympatholytics; Potassium Chloride; Swine; Trachea; Verapamil | 1991 |
Contractile effects of 16-methyl analogues of PGE2 on the circular and longitudinal muscles of the guinea-pig isolated colon.
Topics: 16,16-Dimethylprostaglandin E2; Animals; Atropine; Calcium; Colon; Dinoprostone; Egtazic Acid; Guinea Pigs; Male; Muscle Contraction; Tetrodotoxin; Verapamil | 1991 |
Differential age-dependent attenuation of reflex tachycardia by verapamil in rats.
Topics: Aging; Animals; Atropine; Female; Heart Rate; Nitroprusside; Parasympathetic Nervous System; Phenylephrine; Propranolol; Rats; Rats, Inbred Strains; Reflex; Sympathetic Nervous System; Verapamil | 1991 |
Ca2(+)-evoked [3H]dopamine release from synaptosomes is dependent on neuronal type Ca2+ channels and is not mediated by acetylcholine, glutamate or aspartate release.
Topics: Acetylcholine; Animals; Aspartic Acid; Atropine; Brain; Calcium; Calcium Channels; Cobalt; Culture Techniques; Dopamine; Drug Interactions; Ganglionic Blockers; Glutamates; Glutamic Acid; Hexamethonium; Hexamethonium Compounds; Nifedipine; Rats; Synaptosomes; Verapamil | 1990 |
Changes in cardiovascular responses of conscious rats to endogenous opioids following treatment with catecholamine-depleting agents.
Topics: Animals; Atropine; Blood Pressure; Cardiovascular Physiological Phenomena; Catecholamines; Dynorphins; Endorphins; Enkephalin, Methionine; Heart Rate; Hydroxydopamines; Male; Motor Activity; Naloxone; Narcotics; Neurotoxins; Oxidopamine; Peptide Fragments; Rats; Rats, Inbred Strains; Reserpine; Verapamil | 1990 |
Regulation of postprandial motility in the canine ileum.
Topics: Animals; Atropine; Dogs; Eating; Fasting; Gastrointestinal Motility; Hexamethonium; Hexamethonium Compounds; Ileum; Manometry; Muscle, Smooth; Naloxone; Phentolamine; Propranolol; Prostaglandins H; Verapamil | 1990 |
Arachidonic acid-induced secretion in the rat colon. Indomethacin-resistant neuronal and epithelial actions.
Topics: Animals; Antihypertensive Agents; Arachidonic Acid; Arachidonic Acids; Atropine; Chlorides; Colon; Female; Hexamethonium; Hexamethonium Compounds; Indomethacin; Masoprocol; Rats; Rats, Inbred Strains; Submucous Plexus; Tetrodotoxin; Verapamil | 1990 |
Examination of the potential antiulcer activity of the calcium antagonist propyl-methylenedioxyindene. III. Lack of effect on cysteamine-induced duodenal ulcers in rats.
Topics: Aluminum Hydroxide; Animals; Antacids; Anti-Ulcer Agents; Atropine; Bethanechol Compounds; Calcium Channel Blockers; Cysteamine; Dopamine; Drug Combinations; Duodenal Ulcer; Female; Gastric Acid; Gastrointestinal Motility; Indenes; Magnesium Hydroxide; Rats; Rats, Inbred Strains; Stomach Ulcer; Verapamil | 1990 |
Electrical effects of okadaic acid extracted from black sponge on rabbit sinus node.
Topics: Action Potentials; Animals; Atropine; Calcium; Ethers, Cyclic; Female; In Vitro Techniques; Male; Microelectrodes; Okadaic Acid; Phosphoprotein Phosphatases; Porifera; Propranolol; Rabbits; Sinoatrial Node; Sodium; Verapamil | 1990 |
The effect of ions, ion channel blockers, and ionophores on uptake of vitellogenin into cockroach follicles.
Topics: Amiloride; Animals; Atropine; Calcium Channel Blockers; Cockroaches; Female; In Vitro Techniques; Ions; Ouabain; Ovarian Follicle; Tetraethylammonium Compounds; Valinomycin; Verapamil; Vitellogenins | 1990 |
Effects of various metals on hepatic bile calcium excretion in rats: the stimulatory effect of zinc is mediated through acetylcholine action.
Topics: Acetylcholine; Animals; Atropine; Bile; Calcium; Diltiazem; Homeostasis; Liver; Male; Rats; Rats, Inbred Strains; Verapamil; Zinc | 1990 |
[Routine diagnosis in patients with latent sinus node syndrome].
Topics: Aged; Atropine; Cardiac Pacing, Artificial; Electrocardiography; Female; Heart Rate; Humans; Male; Middle Aged; Propranolol; Sick Sinus Syndrome; Sinoatrial Node; Verapamil | 1990 |
Intracellular calcium homeostasis in a human neuroblastoma cell line: modulation by depolarization, cholinergic receptors, and alpha-latrotoxin.
Topics: Aminoquinolines; Arthropod Venoms; Atropine; Calcimycin; Calcium; Carbachol; Cytoplasm; Egtazic Acid; Fluorescent Dyes; Homeostasis; Humans; Ion Channels; Membrane Potentials; Neuroblastoma; Pirenzepine; Potassium Chloride; Receptors, Cholinergic; Receptors, Muscarinic; Receptors, Nicotinic; Spectrometry, Fluorescence; Spider Venoms; Tumor Cells, Cultured; Verapamil | 1988 |
Comparison of the effects of some muscarinic agonists on smooth muscle function and phosphatidylinositol turnover in the guinea-pig taenia caeci.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Atropine; Calcium; Cecum; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle, Smooth; Nifedipine; Parasympathomimetics; Phosphatidylinositols; Propylbenzilylcholine Mustard; Pyrrolidines; Verapamil | 1988 |
Carbachol-induced cytosolic free Ca2+ increases in T84 colonic cells seen by microfluorimetry.
Topics: Atropine; Calcium; Carbachol; Cell Line; Colonic Neoplasms; Cytosol; Dantrolene; Egtazic Acid; Humans; Kinetics; Microscopy, Fluorescence; Tumor Cells, Cultured; Verapamil | 1989 |
The inotropic effect of 4-aminopyridine and pH changes in rabbit papillary muscle.
Topics: 4-Aminopyridine; Animals; Atropine; Calcium Chloride; Cardiovascular Agents; Cyclic AMP; Cyclic GMP; Heart; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Myocardial Contraction; Papillary Muscles; Rabbits; Verapamil | 1989 |
Pharmacology of calcium-induced long-term potentiation in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Animals; Aspartic Acid; Atropine; Calcium; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Propranolol; Rats; Rats, Inbred Strains; Verapamil | 1989 |
Effects of clenbuterol on resting tension and contractile response in vesicourethral smooth muscle of rabbits.
Topics: Acetylcholine; Adrenergic beta-Agonists; Animals; Atropine; Clenbuterol; Dose-Response Relationship, Drug; Ethanolamines; Flavoxate; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Rabbits; Urethra; Urinary Bladder; Verapamil | 1989 |
[Therapy of acute myocardial infarct].
Topics: Acidosis; Analgesics; Atropine; Bicarbonates; Bradycardia; Cardiac Complexes, Premature; Critical Care; Diazepam; Digitalis Glycosides; Early Ambulation; First Aid; Furosemide; Heparin; Humans; Hypertension; Lidocaine; Myocardial Infarction; Nitroglycerin; Pacemaker, Artificial; Positive-Pressure Respiration; Sodium; Sodium Bicarbonate; Verapamil | 1985 |
Antagonism by tubocurarine and verapamil of the regenerative acetylcholine release from mouse motor nerve.
Topics: Acetylcholine; Animals; Atropine; Calcium Channel Blockers; In Vitro Techniques; Mice; Mice, Inbred ICR; Motor Neurons; Nerve Regeneration; Phrenic Nerve; Receptors, Nicotinic; Tubocurarine; Verapamil | 1989 |
The role of intracellular calcium stores in motilin induced contractions of the longitudinal muscle of the rabbit duodenum.
Topics: Acetylcholine; Animals; Atropine; Calcium; Duodenum; Female; In Vitro Techniques; Isometric Contraction; Male; Membrane Potentials; Motilin; Muscle Contraction; Muscle, Smooth; Nitroprusside; Potassium; Rabbits; Tetrodotoxin; Verapamil | 1989 |
Characterization of contractile prostanoid receptors on human airway smooth muscle.
Topics: Atropine; Biphenyl Compounds; Bronchi; Carbachol; Dinoprost; Dinoprostone; Heptanoic Acids; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Prostaglandin Endoperoxides, Synthetic; Receptors, Prostaglandin; Thromboxane A2; Verapamil | 1989 |
Divergent pharmacological effects of three calmodulin antagonists, N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7), chlorpromazine and calmidazolium, on isometric tension development and myosin light chain phosphorylation in intact bovine trachea
Topics: Animals; Atropine; Calmodulin; Carbachol; Cattle; Chlorpromazine; Imidazoles; In Vitro Techniques; Muscle Contraction; Myosins; Phosphorylation; Potassium Chloride; Sulfonamides; Trachea; Verapamil | 1989 |
Fluoride but not phorbol esters stimulate rat urinary bladder prostanoid synthesis: investigations into the roles of G proteins and protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Atropine; Bucladesine; Calcimycin; Carbachol; Fluorides; GTP-Binding Proteins; Isoquinolines; Nifedipine; Phorbol Esters; Piperazines; Prostaglandins; Protein Kinase C; Protein Kinase Inhibitors; Rats; Rats, Inbred Strains; Urinary Bladder; Verapamil | 1987 |
[Changes in acetylcholine contractions induced by carnitine in coronary vessels isolated "in vitro"].
Topics: Acetylcholine; Animals; Atropine; Calcium; Carnitine; Cattle; Coronary Vessels; Fendiline; In Vitro Techniques; Kinetics; Muscle Contraction; Pyrrolidines; Receptors, Muscarinic; Verapamil | 1985 |
Muscarinic stimulation of prostacyclin synthesis by the rat penis.
Topics: Animals; Atropine; Calcium; Carbachol; Epoprostenol; In Vitro Techniques; Male; Methacholine Compounds; Neurotransmitter Agents; Parasympathomimetics; Penis; Prostaglandins F; Rats; Rats, Inbred Strains; Verapamil | 1986 |
Effects of cold-restraint stress on gastric ulceration and motility in rats.
Topics: Animals; Atropine; Bethanechol; Bethanechol Compounds; Cold Temperature; Female; Gastric Emptying; Gastrointestinal Motility; Rats; Rats, Inbred Strains; Restraint, Physical; Stomach Ulcer; Stress, Physiological; Verapamil | 1986 |
Calcium dependence of muscarinic receptor-mediated catecholamine secretion from the perfused rat adrenal medulla.
Topics: Adrenal Medulla; Animals; Atropine; Calcium; Catecholamines; Egtazic Acid; Electric Stimulation; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Muscarine; Nicotine; Perfusion; Rats; Receptors, Muscarinic; Verapamil | 1987 |
The effects of verapamil on left ventricular function in the presence of beta-adrenergic blockade.
Topics: Adrenergic beta-Antagonists; Animals; Atropine; Cardiac Output; Dogs; Heart; Heart Ventricles; Myocardial Contraction; Propranolol; Prostheses and Implants; Stroke Volume; Systole; Transducers; Ultrasonography; Ventricular Function; Verapamil | 1988 |
The neurosecretory effect of ouabain on isolated rabbit ileal mucosa.
Topics: Animals; Atropine; Biological Transport; Calcium; Chlorides; Electric Conductivity; Ileum; Intestinal Mucosa; Kinetics; Neurotransmitter Agents; Ouabain; Rabbits; Sodium; Tetrodotoxin; Verapamil | 1988 |
Potassium-mediated stimulation of hepatic glycogenolysis.
Topics: Animals; Atrial Natriuretic Factor; Atropine; Egtazic Acid; In Vitro Techniques; Indomethacin; Kinetics; Liver; Liver Glycogen; Masoprocol; Nifedipine; Nitroprusside; Perfusion; Phentolamine; Potassium; Propranolol; Rats; Verapamil | 1987 |
[Effects of atropine on the basilar and mesenteric artery rings and portal vein strips].
Topics: Animals; Atropine; Basilar Artery; Female; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Portal Vein; Rabbits; Verapamil | 1987 |
4-Aminopyridine and haemodialysis in the treatment of verapamil intoxication.
Topics: 4-Aminopyridine; Aged; Aminopyridines; Atropine; Heart Rate; Humans; Male; Renal Dialysis; Time Factors; Verapamil | 1985 |
Ca2+ channel blockers stimulate ileal and colonic water absorption.
Topics: Animals; Atropine; Biological Transport; Body Water; Calcium; Calcium Channel Blockers; Carbachol; Chlorides; Colon; Cyclic AMP; Drug Interactions; Ileum; In Vitro Techniques; Injections, Intraperitoneal; Injections, Intravenous; Intestinal Absorption; Male; Nifedipine; Rabbits; Rats; Rats, Inbred Strains; Sodium; Theophylline; Time Factors; Verapamil | 1985 |
Positive inotropic effect of acetylcholine in canine cardiac Purkinje fibers.
Topics: Acetylcholine; Action Potentials; Animals; Atropine; Calcium; Cyclic GMP; Dogs; Heart Conduction System; Isoproterenol; Membrane Potentials; Microelectrodes; Myocardial Contraction; Nitroprusside; Purkinje Fibers; Receptors, Muscarinic; Stimulation, Chemical; Verapamil | 1985 |
Effects of acetylcholine, TSH and other stimulators on intracellular calcium concentration in dog thyroid cells.
Topics: Acetylcholine; Aminoquinolines; Animals; Atropine; Calcium; Carbachol; Cyclic AMP; Dogs; Egtazic Acid; Fluorescent Dyes; In Vitro Techniques; Spectrometry, Fluorescence; Thyroid Gland; Thyrotropin; Verapamil | 1985 |
Phosphoinositide phosphorylation and hydrolysis in pancreatic islet cell membrane.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Atropine; Calcium; Carbachol; Carbon Radioisotopes; Cell Membrane; Egtazic Acid; Hydrolysis; In Vitro Techniques; Islets of Langerhans; Membrane Lipids; Phosphatidylinositols; Phosphorus Radioisotopes; Phosphorylation; Rats; Verapamil | 1986 |
Effects of calcium antagonist TMB-8 on active Na and Cl transport in rabbit ileum.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Atropine; Biological Transport, Active; Calcium; Calcium Channel Blockers; Carbachol; Cell Membrane; Chlorides; Cyclic AMP; Gallic Acid; Ileum; Intestinal Absorption; Intestinal Mucosa; Male; Rabbits; Serotonin; Sodium; Verapamil | 1986 |
Treatment of verapamil toxicity in intact dogs.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Atropine; Blood Pressure; Calcium Chloride; Cardiac Output; Dogs; Dopamine; Epinephrine; Heart Rate; Isoproterenol; Norepinephrine; Phenylephrine; Stimulation, Chemical; Stroke Volume; Verapamil | 1986 |
Stimulation by glucose and carbamylcholine of phospholipase C in pancreatic islets.
Topics: Animals; Atropine; Calcium; Carbachol; Gliclazide; Glucose; In Vitro Techniques; Inositol; Islets of Langerhans; Phosphatidylinositols; Potassium; Rats; Rats, Inbred Strains; Tritium; Type C Phospholipases; Verapamil | 1985 |
Effects of forskolin on pancreatic exocrine secretion and cyclic nucleotide concentrations of the dog pancreas.
Topics: Animals; Atropine; Cimetidine; Colforsin; Cyclic AMP; Cyclic GMP; Dogs; Female; Male; Nucleotides, Cyclic; Pancreatic Juice; Phentolamine; Propranolol; Sulpiride; Verapamil | 1987 |
Effects of nicotine on spontaneous contractions of isolated atria of toad (Bufo melanostictus).
Topics: Animals; Atropine; Bufonidae; Caffeine; Edetic Acid; Hemicholinium 3; Hexamethonium Compounds; Hydroxydopamines; In Vitro Techniques; Myocardial Contraction; Nicotine; Oxidopamine; Physostigmine; Tyramine; Verapamil | 1987 |
Correction of systolic time intervals for heart rate: a comparison of individual with population derived regression equations.
Topics: Adult; Atropine; Calcium Channel Blockers; Diltiazem; Electrocardiography; Female; Heart Rate; Humans; Male; Nifedipine; Phonocardiography; Propranolol; Regression Analysis; Verapamil | 1988 |
The effect of verapamil, diltiazem and nifedipine on baroreceptor reflexes.
Topics: Animals; Atropine; Blood Pressure; Diltiazem; Heart Rate; Male; Nifedipine; Phenylephrine; Pressoreceptors; Propranolol; Rats; Rats, Inbred Strains; Reflex; Verapamil | 1988 |
Calcium transients evoked by electrical stimulation of smooth muscle from guinea-pig ileum recorded by the use of Fura-2.
Topics: Action Potentials; Animals; Atropine; Benzofurans; Calcium; Fura-2; Guinea Pigs; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Tetrodotoxin; Time Factors; Verapamil | 1988 |
Cardiovascular effects of prostaglandin I2 and prostaglandin F2 alpha in the unanesthetized bullfrog, Rana catesbeiana.
Topics: Animals; Atropine; Blood Pressure; Calcium; Dinoprost; Dose-Response Relationship, Drug; Epoprostenol; Heart Rate; Hematocrit; Parasympathetic Nervous System; Propranolol; Prostaglandins F; Rana catesbeiana; Sympathetic Nervous System; Verapamil | 1988 |
Lacinilene C methyl ether (LCME) constricts tracheal smooth muscle.
Topics: Animals; Atropine; Dogs; Drug Interactions; In Vitro Techniques; Isoproterenol; Methysergide; Muscle Contraction; Muscle, Smooth; Naphthols; Pyrilamine; Trachea; Verapamil | 1988 |
In vitro red tide toxin effects on human bronchial smooth muscle.
Topics: Acetylcholine; Aged; Animals; Atropine; Bronchi; Dinoflagellida; Dogs; Dose-Response Relationship, Drug; Female; Humans; Male; Marine Toxins; Middle Aged; Muscle, Smooth; Tetrodotoxin; Verapamil | 1988 |
Potentiation of cardiac electrophysiologic effects of verapamil after autonomic blockade or cardiac transplantation.
Topics: Animals; Atrioventricular Node; Atropine; Autonomic Nerve Block; Dogs; Drug Synergism; Heart; Heart Transplantation; Propranolol; Refractory Period, Electrophysiological; Time Factors; Verapamil | 1987 |
Effects of cooling on the contractile response of the rat tracheal muscle to pilocarpine in vitro.
Topics: Animals; Atropine; Calcium; Carbachol; Cold Temperature; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Physostigmine; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Tetrodotoxin; Trachea; Verapamil | 1987 |
Lower airway smooth muscle contraction induced by Ptychodiscus brevis (red tide) toxin.
Topics: Acetylcholine; Alprostadil; Animals; Atropine; Dogs; Marine Toxins; Muscle Contraction; Muscle, Smooth; Neostigmine; Tetrodotoxin; Verapamil | 1987 |
Interactive negative chronotropic actions of adenosine and verapamil on the canine sinus node in vivo.
Topics: Adenosine; Animals; Atrioventricular Node; Atropine; Blood Pressure; Dogs; Drug Interactions; Heart Rate; Propranolol; Sinoatrial Node; Vagotomy; Verapamil | 1987 |
Effects of calcium antagonistic drugs on the electrical activity of rabbit sino-atrial node.
Topics: Animals; Atropine; Calcium Channel Blockers; Electric Stimulation; In Vitro Techniques; Membrane Potentials; Nifedipine; Rabbits; Sinoatrial Node; Verapamil | 1986 |
[Differential therapeutic problems in sinus node syndrome--drug or electrical therapy?].
Topics: Anti-Arrhythmia Agents; Atropine; Bundle of His; Cardiac Glycosides; Disopyramide; Drug Therapy, Combination; Electrocardiography; Female; Humans; Male; Metaproterenol; Middle Aged; Pacemaker, Artificial; Prognosis; Sick Sinus Syndrome; Sinoatrial Node; Verapamil | 1986 |
Source of calcium and cholinergic contraction of the rat portal vein and the sheep coronary artery.
Topics: Acetylcholine; Animals; Atropine; Caffeine; Calcium; Cobalt; Coronary Vessels; Culture Media; Female; Muscle Contraction; Muscle, Smooth, Vascular; Parasympathetic Nervous System; Portal Vein; Rats; Rats, Inbred Strains; Sheep; Sodium; Verapamil | 1986 |
Effect of verapamil on cardiac chronotropic response to vagal stimulation in neonatal pigs.
Topics: Animals; Animals, Newborn; Atropine; Blood Pressure; Female; Heart Rate; Male; Propranolol; Swine; Vagus Nerve; Verapamil | 1985 |
Effect of progesterone on canine colonic smooth muscle.
Topics: Animals; Atropine; Colon; Dogs; Electromyography; Gastrointestinal Motility; In Vitro Techniques; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Potassium; Progesterone; Tetrodotoxin; Verapamil | 1985 |
Interaction of verapamil hydrochloride and atropine sulphate on histamine-induced bronchoconstriction.
Topics: Airway Resistance; Animals; Atropine; Bronchial Diseases; Constriction, Pathologic; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Female; Histamine; Male; Verapamil | 1985 |
Relative activities of three calcium channel antagonists on histamine, acetylcholine and antigen-induced contractions of guinea pig ileum.
Topics: Acetylcholine; Animals; Antigens; Atropine; Calcium Channel Blockers; Diltiazem; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Male; Muscle Contraction; Nifedipine; Ovalbumin; Tripelennamine; Verapamil | 1985 |
[What is assured in the treatment of heart arrhythmia?].
Topics: Adrenergic beta-Antagonists; Ajmaline; Atrial Fibrillation; Atrial Flutter; Atropine; Bradycardia; Cardiac Complexes, Premature; Heart Block; Humans; Lidocaine; Metaproterenol; Phenytoin; Procainamide; Quinidine; Tachycardia; Verapamil | 1972 |
[Intra-myocardial contrast injection (author's transl)].
Topics: Animals; Arrhythmias, Cardiac; Atropine; Cardiac Complexes, Premature; Contrast Media; Dogs; Female; Heart; Injections, Intramuscular; Male; Microscopy, Electron; Muscles; Myocardium; Norepinephrine; Radiography; Thorium Dioxide; Ventricular Fibrillation; Verapamil | 1974 |
[Modern therapy of cardiac arrhythmias].
Topics: Adrenergic beta-Antagonists; Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Bradycardia; Humans; Lidocaine; Metaproterenol; Phenytoin; Procainamide; Quinidine; Tachycardia; Verapamil | 1973 |
Action of verapamil on sinus node, atrioventricular, and intraventricular conduction.
Topics: Adult; Aged; Alprenolol; Arrhythmias, Cardiac; Atropine; Electrocardiography; Heart Block; Heart Conduction System; Humans; Middle Aged; Pacemaker, Artificial; Sinoatrial Node; Verapamil | 1973 |
[Some suggestions for the treatment of myocardial infarct in the pre-hospitalization phase].
Topics: Allied Health Personnel; Ambulances; Angina Pectoris; Arrhythmias, Cardiac; Atropine; Droperidol; Health Education; Heart Arrest; Humans; Lidocaine; Metaproterenol; Morphine; Myocardial Infarction; Shock, Cardiogenic; Time Factors; Verapamil; Vomiting | 1973 |
Effects of agents which inhibit the slow channel on sinus node automaticity and atrioventricular conduction in the dog.
Topics: Action Potentials; Animals; Atropine; Calcium; Chlorides; Depression, Chemical; Dogs; Epinephrine; Female; Glucagon; Heart Conduction System; Isoproterenol; Lanthanum; Male; Manganese; Phenylephrine; Propranolol; Sinoatrial Node; Sodium; Verapamil | 1974 |
[The antiarrhythmic action mechanism of verapamil (Isoptin)].
Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Atropine; Blood Pressure; Drug Antagonism; Heart Conduction System; Heart Rate; Humans; Hypotension; Injections, Intravenous; Metaproterenol; Tachycardia, Paroxysmal; Time Factors; Vascular Resistance; Verapamil | 1971 |
Transient increase in the slow inward current following acetylcholine removal in catecholamine-treated guinea-pig Purkinje fibers.
Topics: Acetylcholine; Animals; Atropine; Cadmium; Calcium; Guinea Pigs; Heart Conduction System; Ion Channels; Isoproterenol; Purkinje Fibers; Verapamil | 1984 |
Different, dose-dependent effects of verapamil inhalation on histamine-induced bronchoconstriction in anaesthetized dogs.
Topics: Aerosols; Airway Resistance; Anesthesia; Animals; Atropine; Bronchi; Dogs; Dose-Response Relationship, Drug; Female; Histamine H1 Antagonists; Male; Verapamil | 1984 |
beta-Adrenergic stimulation of the adenosine 3',5'-monophosphate system regulated by cholinergic stimuli in the prostate.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Atropine; Calcimycin; Calcium; Cell Membrane; Cyclic AMP; Hexamethonium; Hexamethonium Compounds; Isoproterenol; Male; Parasympathetic Nervous System; Prostate; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Tetracaine; Theophylline; Verapamil | 1983 |
Simultaneous AV nodal reentrant and ventricular tachycardias.
Topics: Anti-Arrhythmia Agents; Atrioventricular Node; Atropine; Bundle of His; Electrocardiography; Female; Heart Conduction System; Heart Rate; Heart Ventricles; Humans; Middle Aged; Tachycardia; Verapamil | 1984 |
Properties of an acetylcholine-induced conductance in the rabbit atrial myocardium.
Topics: Acetylcholine; Action Potentials; Animals; Atrial Function; Atropine; Cell Membrane; Heart Atria; In Vitro Techniques; Ion Channels; Membrane Potentials; Microelectrodes; Potassium; Rabbits; Verapamil | 1981 |
Effects of SG-75 (nicorandil) on electrical activity of canine cardiac Purkinje fibers: possible increase in potassium conductance.
Topics: Action Potentials; Animals; Atropine; Barium; Dogs; Electrophysiology; Female; Heart Conduction System; Ion Channels; Male; Niacinamide; Nicorandil; Potassium; Purkinje Fibers; Solutions; Stress, Mechanical; Verapamil | 1983 |
Possible mechanisms involved in the spontaneous rhythmicity in the guinea-pig tracheal smooth muscle as induced by glucose removal.
Topics: Animals; Atropine; Calcimycin; Female; Glucose; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Ouabain; Propranolol; Tetrodotoxin; Verapamil | 1983 |
The effect of nifedipine and verapamil on KC1-induced rhythmic contractions of guinea pig ureter in vitro.
Topics: Animals; Atropine; Calcium; Edetic Acid; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Periodicity; Phentolamine; Potassium Chloride; Procaine; Ureter; Urethane; Verapamil | 1984 |
Effect of 2-nicotinamidethyl nitrate (SG-75) on the membrane potential of left atrial muscle fibres of the dog. Increase in potassium conductance.
Topics: Animals; Atropine; Chlorides; Dogs; Drug Interactions; Heart; In Vitro Techniques; Membrane Potentials; Methacholine Compounds; Neural Conduction; Niacinamide; Nicorandil; Nitrates; Ouabain; Potassium; Vasodilator Agents; Verapamil | 1980 |
The nature of the stimulatory action of gamma-aminobutyric acid in the isolated perfused dog adrenals.
Topics: Acetylcholine; Adrenal Glands; Animals; Atropine; Bicuculline; Calcium; Catecholamines; Cobalt; Dibucaine; Dogs; Female; gamma-Aminobutyric Acid; Hexamethonium Compounds; In Vitro Techniques; Kinetics; Male; Picrotoxin; Tetrodotoxin; Verapamil | 1984 |
The effect of gallamine, gallopamil and nifedipine on responses to acetylcholine and carbachol in the taenia of the guinea-pig caecum.
Topics: Acetylcholine; Animals; Atropine; Calcium; Carbachol; Cecum; Drug Interactions; Gallamine Triethiodide; Gallopamil; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Nifedipine; Paraoxon; Time Factors; Verapamil | 1984 |
Mechanism of smooth muscle relaxation by rociverine.
Topics: Animals; Atropine; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Calcium; Cyclohexanecarboxylic Acids; Drug Interactions; Guinea Pigs; Histamine; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Myocardial Contraction; Norepinephrine; Papaverine; Parasympatholytics; Potassium; Rabbits; Rats; Rats, Inbred Strains; Verapamil | 1984 |
Eserine-induced hypertone of guinea pig distal colon in vivo: a new pharmacological procedure for testing smooth muscle relaxants.
Topics: Animals; Atropine; Benzodiazepinones; Colon; Dicyclomine; Dose-Response Relationship, Drug; Guinea Pigs; Male; Methods; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Physostigmine; Pirenzepine; Quaternary Ammonium Compounds; Verapamil | 1984 |
On the inhibitory mechanism of bassianolide, a cyclodepsipeptide, in acetylcholine-induced contraction in guinea-pig taenia coli.
Topics: Acetylcholine; Animals; Atropine; Calcium; Colon; Guinea Pigs; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Papaverine; Peptides, Cyclic; Potassium; Sodium; Verapamil | 1983 |
Blockade by verapamil of cholinergic effects on atrial specialised tissue in the anaesthetised dog.
Topics: Acetylcholine; Animals; Atropine; Dextromoramide; Dogs; Electrocardiography; Heart Atria; Heart Conduction System; Heart Rate; Sinoatrial Node; Vagotomy; Vagus Nerve; Verapamil | 1983 |
Pathophysiology and treatment of coronary arterial spasm.
Topics: Adult; Angina Pectoris; Angina Pectoris, Variant; Atropine; Calcium; Coronary Disease; Coronary Vessels; Diltiazem; Female; Humans; Male; Nifedipine; Nitroglycerin; Phenoxybenzamine; Physical Exertion; Propranolol; Spasm; Verapamil | 1980 |
The influence of verapamil on the amplitude and frequency of cholinergic-initiated contractions of isolated gastric muscularis muscle of Bufo marinus.
Topics: Acetylcholine; Animals; Atropine; Bufo marinus; Calcium; In Vitro Techniques; Muscle Contraction; Stomach; Verapamil | 1982 |
Reflex chronotropic and inotropic effects of calcium channel-blocking agents in conscious dogs. Diltiazem, verapamil, and nifedipine compared.
Topics: Animals; Atropine; Calcium Channel Blockers; Diltiazem; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Male; Myocardial Contraction; Nifedipine; Propranolol; Verapamil | 1983 |
In vivo rat bladder: a new model to screen spasmolytic compounds.
Topics: Acetylcholine; Animals; Atropine; Barium; Barium Compounds; Chlorides; Drug Evaluation, Preclinical; Female; Parasympatholytics; Potassium Chloride; Rats; Rats, Inbred Strains; Urinary Bladder; Verapamil | 1983 |
Differential effect of verapamil isomers on sinus node and AV junctional region.
Topics: Animals; Atrioventricular Node; Atropine; Dogs; Female; Heart Block; Heart Conduction System; Heart Rate; Kinetics; Male; Sinoatrial Node; Stereoisomerism; Verapamil | 1983 |
The effects of nifedipine and verapamil on high K+ induced contractions of the rat intestinal tract in vivo.
Topics: Animals; Atropine; Blood Pressure; Duodenum; Heart Rate; Intestines; Male; Muscle Contraction; Muscle Relaxation; Nifedipine; Potassium; Pyridines; Rats; Rats, Inbred Strains; Verapamil | 1983 |
Effects of magnesium on the isolated, blood-perfused atrial and ventricular preparations of the dog heart.
Topics: Acetylcholine; Animals; Atropine; Calcium; Depression, Chemical; Dogs; Heart; Heart Rate; In Vitro Techniques; Magnesium; Myocardial Contraction; Perfusion; Verapamil | 1981 |
A basis for the pharmacology of hearing.
Topics: Acetylcholine; Action Potentials; Animals; Atropine; Brain; Calcium; Cochlea; Digoxin; Efferent Pathways; Guinea Pigs; Hearing; Humans; Physostigmine; Verapamil | 1980 |
A pharmacological approach to the study of AV conduction in man.
Topics: Adolescent; Adult; Aged; Ajmaline; Atrioventricular Node; Atropine; Female; Heart Conduction System; Humans; Male; Middle Aged; Neural Conduction; Refractory Period, Electrophysiological; Verapamil | 1980 |
Depolarization of cell membrane is associated with an increase in ciliary beat frequency (CBF).
Topics: Amiloride; Animals; Atropine; Carbachol; Cell Membrane; Cells, Cultured; Cilia; Fluorescent Dyes; Ionomycin; Kinetics; Microscopy, Fluorescence; Muscarinic Agonists; Photons; Pyridinium Compounds; Receptors, Muscarinic; Scattering, Radiation; Sheep; Time Factors; Trachea; Verapamil | 1995 |
Chronotropic cardiac effects of falipamil in conscious dogs: interactions with the autonomic nervous system and various ionic conductances.
Topics: Animals; Atropine; Autonomic Nervous System; Blood Pressure; Cardiovascular Agents; Dogs; Female; Heart Rate; Ion Channels; Isoindoles; Male; Phthalimides; Pindolol; Quinidine; Receptors, Adrenergic, beta; Receptors, Muscarinic; Stimulation, Chemical; Verapamil | 1994 |
Phasic contractions of the muscular components of human esophagus and gastroesophageal junction in vitro.
Topics: Adult; Aged; Aged, 80 and over; Atropine; Carbachol; Electrophysiology; Esophagogastric Junction; Esophagus; Female; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Smooth; Tetrodotoxin; Verapamil | 1995 |
Bursting firing of action potentials in central snail neurons elicited by d-amphetamine: role of the electrogenic sodium pump.
Topics: Action Potentials; Animals; Atropine; Dextroamphetamine; Dose-Response Relationship, Drug; Edetic Acid; Esophagus; Haloperidol; Hexamethonium; Magnesium; Neurons; Ouabain; Patch-Clamp Techniques; Phenobarbital; Potassium; Prazosin; Propranolol; Snails; Sodium; Sodium-Potassium-Exchanging ATPase; Temperature; Tubocurarine; Verapamil | 1995 |
Effect of levamisole hydrochloride on the guinea-pig atrium.
Topics: Animals; Arrhythmias, Cardiac; Atropine; Disease Models, Animal; Drug Antagonism; Drug Evaluation, Preclinical; Electric Stimulation; Female; Guinea Pigs; Heart Atria; Hexamethonium; In Vitro Techniques; Levamisole; Lidocaine; Male; Practolol; Verapamil | 1993 |
Influence of autonomic blockade and aging on AV conduction and responses to verapamil in the beagle.
Topics: Aging; Animals; Atrioventricular Node; Atropine; Autonomic Nervous System; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Female; Heart Block; Heart Rate; Male; Parasympathetic Nervous System; Pentobarbital; Propranolol; Receptors, Adrenergic, beta; Verapamil | 1995 |
Anticholinesterases and experimental envenomation by Naja.
Topics: Animals; Aspirin; Atropine; Cholinesterase Inhibitors; Drug Therapy, Combination; Elapid Venoms; Elapidae; Female; Lethal Dose 50; Lysine; Mice; Neostigmine; Pyridostigmine Bromide; Snake Bites; Verapamil | 1994 |
[Effects of atropine on contraction of rabbit aortic smooth muscle and cell proliferation].
Topics: Animals; Aorta, Thoracic; Atropine; Calcium Chloride; Cell Division; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Potassium Chloride; Rabbits; Verapamil | 1993 |
Analysis of regional hemodynamic regulation in response to scald injury.
Topics: Adamantane; Animals; Arginine; Atropine; Blood Pressure; Burns; Diphenhydramine; Dogs; Femoral Artery; Hemodynamics; Hindlimb; Histamine; Isoproterenol; Meclofenamic Acid; Methoxamine; Methysergide; Morpholines; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitroglycerin; Pulmonary Circulation; Ranitidine; Regional Blood Flow; Ritanserin; Serotonin; Serotonin Receptor Agonists; Time Factors; Triazines; Ultrasonography; Vascular Resistance; Vasodilation; Verapamil; Xanthines | 1994 |
Luminal bile salts and neurotensin release in the isolated vascularly perfused rat jejuno-ileum.
Topics: Animals; Atropine; Bile Acids and Salts; Cattle; Cholic Acid; Cholic Acids; Egtazic Acid; Glycocholic Acid; Ileum; In Vitro Techniques; Jejunum; Kinetics; Male; Neurotensin; Oleic Acid; Oleic Acids; Perfusion; Rats; Rats, Wistar; Taurine; Taurocholic Acid; Taurodeoxycholic Acid; Tetrodotoxin; Time Factors; Verapamil | 1994 |
Effects of calcium chloride on verapamil- and diltiazem-pretreated isolated rat hearts.
Topics: Animals; Atrioventricular Node; Atropine; Calcium; Calcium Chloride; Depression, Chemical; Diltiazem; Drug Interactions; Electrocardiography; Heart; Heart Block; Heart Rate; Male; Rats; Rats, Wistar; Ventricular Function, Left; Ventricular Pressure; Verapamil | 1993 |
Role of calcium in mediating the biphasic contraction of the rabbit urinary bladder.
Topics: Adenosine Triphosphate; Animals; Atropine; Bethanechol Compounds; Calcium; Diltiazem; Electric Stimulation; Extracellular Space; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Rabbits; Urinary Bladder; Verapamil | 1993 |
A one-year evaluation of calcium channel blocker overdoses: toxicity and treatment.
Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Atropine; Calcium; Calcium Channel Blockers; Child; Child, Preschool; Diltiazem; Dopamine; Drug Overdose; Evaluation Studies as Topic; Female; Heart Block; Humans; Hypotension; Infant; Male; Middle Aged; Nifedipine; Prospective Studies; Verapamil | 1993 |
Excitatory action of [Leu13]motilin on the gastrointestinal smooth muscle isolated from the chicken.
Topics: Acetylcholine; Animals; Atropine; Calcium; Chickens; Digestive System; Dimethylphenylpiperazinium Iodide; Dose-Response Relationship, Drug; Electric Stimulation; Gastrointestinal Motility; Hormones; In Vitro Techniques; Intestines; Male; Motilin; Muscle Contraction; Muscle, Smooth; Neuroeffector Junction; Proventriculus; Species Specificity; Tetrodotoxin; Verapamil | 1995 |
Pharmacologic characterization of wool dust extract in isolated guinea pig trachea.
Topics: Air Pollutants, Occupational; Animals; Atropine; Bronchoconstriction; Calcium Channel Blockers; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Dust; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Indomethacin; Leukotriene Antagonists; Male; Occupational Exposure; Pyrilamine; Trachea; Verapamil; Wool | 1995 |
Lack of calcium-antagonizing activity of dehydroevodiamine on the chronotropic and inotropic activities of mouse isolated atria.
Topics: Alkaloids; Animals; Atropine; Calcium Channel Blockers; Heart Atria; Heart Rate; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Myocardial Contraction; Verapamil | 1996 |
Influence of adrenergic and cholinergic mediators on the equine jejunum in vitro.
Topics: Acetylcholine; Adrenergic Agonists; Adrenergic Antagonists; Animals; Atropine; Brimonidine Tartrate; Calcium Channel Blockers; Cholinergic Agonists; Cholinergic Antagonists; Dose-Response Relationship, Drug; Horses; Isoproterenol; Jejunum; Muscle Contraction; Muscle, Smooth; Norepinephrine; Oxymetazoline; Parasympathetic Nervous System; Phentolamine; Phenylephrine; Prazosin; Quinoxalines; Sympathetic Nervous System; Tetrodotoxin; Verapamil; Yohimbine | 1996 |
The effect of Phoneutria nigriventer (armed spider) venom on arterial blood pressure of anaesthetised rats.
Topics: Acetylcholine; Animals; Atropine; Blood Pressure; Isoproterenol; Male; Rats; Rats, Wistar; Spider Venoms; Verapamil | 1996 |
Effect of cisplatin on dopamine release from PC12 cells.
Topics: Animals; Antineoplastic Agents; Atropine; Calcium; Calcium Channel Blockers; Carbachol; Carboplatin; Cell Survival; Cisplatin; Cyclophosphamide; Dopamine; Muscarinic Agonists; Muscarinic Antagonists; PC12 Cells; Potassium Chloride; Rats; Verapamil | 1996 |
High carbachol increases the electrically induced [Ca2+]i transient in the single isolated ventricular myocyte of rats.
Topics: Animals; Atropine; Caffeine; Calcium; Carbachol; Electric Stimulation; Heart; In Vitro Techniques; Muscarinic Agonists; Nickel; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Ryanodine; Sodium; Verapamil; Virulence Factors, Bordetella | 1997 |
PACAPs stimulate duodenal bicarbonate secretion at PACAP receptors in the rat.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Atropine; Bicarbonates; Cyclic AMP; Dinoprostone; Duodenum; Gastric Mucosa; Indomethacin; Male; Neuropeptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, Pituitary Hormone; Secretory Rate; Vagotomy; Vagus Nerve; Vasoactive Intestinal Peptide; Verapamil | 1997 |
Effect of 4-aminopyridine and 3,4-diaminopyridine on guinea-pig isolated ileum.
Topics: 4-Aminopyridine; Acetylcholine; Amifampridine; Animals; Atropine; Calcium Channel Blockers; Diazoxide; Diltiazem; Dose-Response Relationship, Drug; Drug Interactions; Female; Flunarizine; Guinea Pigs; Ileum; In Vitro Techniques; Lanthanum; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Parasympathetic Nervous System; Parasympatholytics; Potassium Channels; Vasodilator Agents; Verapamil | 1997 |
Mechanism of action of honey bee (Apis mellifera L.) venom on different types of muscles.
Topics: Animals; Atropine; Bee Venoms; Bufonidae; Calcium Channel Blockers; Electrocardiography; Heart; Heart Conduction System; Heart Rate; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Skeletal; Muscle, Smooth; Myocardial Contraction; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rabbits; Verapamil | 1998 |
Physiology of the escape rhythm after radiofrequency atrioventricular junctional ablation.
Topics: Adenosine; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrioventricular Node; Atropine; Bundle-Branch Block; Cardiac Pacing, Artificial; Cardiotonic Agents; Catheter Ablation; Female; Heart Rate; Humans; Isoproterenol; Lidocaine; Male; Verapamil | 1998 |
Transepithelial transport of nicotine and vinblastine in isolated malpighian tubules of the tobacco hornworm (Manduca sexta) suggests a P-glycoprotein-like mechanism.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Atropine; Biological Transport; Epithelium; Malpighian Tubules; Manduca; Nicotine; Verapamil; Vinblastine | 1998 |
[Effects of propiverine hydrochloride (propiverine) on isolated rat and dog urinary bladder].
Topics: Acetylcholine; Animals; Atropine; Benzilates; Butylamines; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Female; In Vitro Techniques; Male; Mandelic Acids; Muscarinic Antagonists; Muscle Contraction; Parasympatholytics; Potassium Chloride; Propantheline; Rats; Rats, Wistar; Urinary Bladder; Urination; Urination Disorders; Vasodilator Agents; Verapamil | 1999 |
Relaxant action produced by sodium nitroprusside in guinea-pig tracheal muscle.
Topics: Animals; Atropine; Calcium; Cyclic GMP; Dinoprostone; Female; Fura-2; Guinea Pigs; Indoles; Indomethacin; Male; Muscle Relaxation; Nitroprusside; Terbutaline; Trachea; Verapamil | 1999 |
Antispasmodic action of propinox on the isolated human gallbladder: possible mechanism of action.
Topics: Animals; Atropine; Binding Sites; Butylscopolammonium Bromide; Calcium Channel Blockers; Carbachol; Gallbladder; Humans; Mandelic Acids; Muscarinic Agonists; Muscarinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Verapamil | 1999 |
A Na+/Ca2+ exchanger inhibitor, KB-R7943, caused negative inotropic responses and negative followed by positive chronotropic responses in isolated, blood-perfused dog heart preparations.
Topics: Animals; Atropine; Depression, Chemical; Dogs; Dose-Response Relationship, Drug; Heart Rate; Hexamethonium; Imipramine; Isoproterenol; Myocardial Contraction; Ouabain; Perfusion; Propranolol; Sodium-Calcium Exchanger; Tetrodotoxin; Thiourea; Verapamil | 2000 |
Atropine for therapy refractory acute coronary spasm.
Topics: Atropine; Coronary Vasospasm; Humans; Muscarinic Antagonists; Nitroglycerin; Treatment Failure; Vasodilator Agents; Verapamil | 2000 |
[Acute verapamil poisoning. A proposal of a strategy for therapeutic management].
Topics: Acute Disease; Adrenergic beta-Agonists; Aged; Atropine; Calcium Channel Blockers; Cardiotonic Agents; Dobutamine; Epinephrine; Fluid Therapy; Heart Block; Humans; Isoproterenol; Male; Muscarinic Antagonists; Shock; Sorption Detoxification; Verapamil | 2000 |
Enantiomer separation by strong anion-exchange capillary electrochromatography with dynamically modified sulfated beta-cyclodextrin.
Topics: Anions; Atropine; beta-Cyclodextrins; Cyclodextrins; Electrophoresis, Capillary; Metoprolol; Molecular Structure; Praziquantel; Tryptophan; Verapamil | 2001 |
Pharmacology and chemistry of the venoms of solitary wasps.
Topics: Animals; Atropine; Bufonidae; Drug Antagonism; Electrocardiography; Electrophoresis; Gallamine Triethiodide; Heart; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Skeletal; Muscle, Smooth; Muscles; Myocardium; Nicotinic Antagonists; Rabbits; Species Specificity; Verapamil; Wasp Venoms; Wasps | 2002 |
Type 5 adenylyl cyclase disruption alters not only sympathetic but also parasympathetic and calcium-mediated cardiac regulation.
Topics: Acetylcholine; Adenylyl Cyclases; Animals; Atropine; Binding, Competitive; Blotting, Western; Calcium; Calcium Channel Blockers; Calcium Channels; Cardiotonic Agents; Electrocardiography; Female; Genotype; Heart; Heart Rate; Isoenzymes; Isoproterenol; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Muscarinic Antagonists; Myocardium; Parasympathetic Nervous System; Potassium Channels; Receptors, Adrenergic, beta; Sympathetic Nervous System; Vasodilator Agents; Verapamil | 2003 |
Pharmacological actions of Heteromorpha trifoliata ("dombwe") on rat isolated muscle preparations.
Topics: Alcuronium; Animals; Apiaceae; Atropine; Calcium Channel Blockers; Cyproheptadine; Drug Evaluation, Preclinical; Female; In Vitro Techniques; Male; Medicine, African Traditional; Muscarinic Antagonists; Muscle Contraction; Muscle, Skeletal; Myometrium; Nicotinic Antagonists; Phytotherapy; Plant Bark; Plant Extracts; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT2; Serotonin Antagonists; Uterine Contraction; Verapamil; Zimbabwe | 2000 |
Inhibitory effect of the antidepressant St. John's wort (hypericum perforatum) on rat bladder contractility in vitro.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Anthracenes; Antidepressive Agents; Atropine; Bridged Bicyclo Compounds; Capsaicin; Depression; Electric Stimulation; Female; Haloperidol; Hypericum; Kaempferols; Male; Methysergide; Muscle Contraction; Muscle, Smooth; Naloxone; Perylene; Phentolamine; Phloroglucinol; Piperidines; Plant Extracts; Propranolol; Pyrazoles; Quercetin; Rats; Rats, Wistar; Rimonabant; Rutin; Terpenes; Tetrodotoxin; Urinary Bladder; Urinary Incontinence; Verapamil | 2004 |
Effect of rhubarb on contractile response of gallbladder smooth muscle strips isolated from guinea pigs.
Topics: Adrenergic alpha-Antagonists; Animals; Anti-Arrhythmia Agents; Atropine; Drug Interactions; Female; Gallbladder; Ganglionic Blockers; Guinea Pigs; Hexamethonium; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Phentolamine; Plant Preparations; Rheum; Verapamil | 2005 |
In vivo gastric and intestinal slow waves in W/WV mice.
Topics: Anesthesia; Animals; Atropine; Biological Clocks; Central Nervous System; Electrophysiology; Enteric Nervous System; Intestines; Male; Mice; Mice, Mutant Strains; Muscle, Smooth; Myoelectric Complex, Migrating; Stomach; Verapamil | 2005 |
Effect of toluene diisocyanate on homeostasis of intracellular-free calcium in human neuroblastoma SH-SY5Y cells.
Topics: Atropine; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Signaling; Cell Line, Tumor; Cytosol; Dose-Response Relationship, Drug; Drug Synergism; Egtazic Acid; Endoplasmic Reticulum; Hexamethonium; Homeostasis; Humans; Intracellular Fluid; Ionomycin; Methacholine Chloride; Neuroblastoma; Potassium; Pyridines; Receptor, Muscarinic M3; Thapsigargin; Toluene 2,4-Diisocyanate; Verapamil | 2006 |
An inherent acceleratory effect of insulin on small intestinal transit and its pharmacological characterization in normal mice.
Topics: Animals; Atropine; Calcium Channels; Clonidine; Gastrointestinal Transit; Glyburide; Insulin; Insulin Secretion; Intestine, Small; Male; Mice; Naloxone; Ondansetron; Receptors, Opioid; Verapamil | 2006 |
Endothelium-dependent induction of vasorelaxation by the butanol extract of Phellinus igniarius in isolated rat aorta.
Topics: Animals; Aorta; Atropine; Butanols; Cyclic GMP; Diltiazem; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; In Vitro Techniques; Indomethacin; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Oxadiazoles; Polyporaceae; Propranolol; Quinoxalines; Rats; Rats, Sprague-Dawley; Tetraethylammonium; Vasodilation; Vasodilator Agents; Verapamil | 2006 |
Enteric descending and afferent neural signaling stimulated by giant migrating contractions: essential contributing factors to visceral pain.
Topics: Afferent Pathways; Animals; Atropine; Calcitonin Gene-Related Peptide; Colic; Dogs; Enteric Nervous System; Female; Gastrointestinal Motility; Heart Rate; Inflammatory Bowel Diseases; Intestine, Small; Irritable Bowel Syndrome; Male; Methacholine Chloride; Muscarinic Antagonists; Muscle Contraction; Myoelectric Complex, Migrating; NG-Nitroarginine Methyl Ester; Nicotinic Agonists; Nitric Oxide Synthase; Purinergic P2 Receptor Antagonists; Receptors, Tachykinin; Serotonin Antagonists; Verapamil | 2007 |
Azithromycin has a direct relaxant effect on precontracted airway smooth muscle.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Anti-Bacterial Agents; Atropine; Azithromycin; Bronchodilator Agents; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Carbachol; Enzyme Inhibitors; Epithelium; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Muscarinic Agonists; Muscle Contraction; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; Ouabain; Phosphodiesterase Inhibitors; Potassium Chloride; Protein Serine-Threonine Kinases; Rabbits; rho-Associated Kinases; Trachea; Verapamil | 2006 |
In vitro pharmacological characterization of mitemcinal (GM-611), the first acid-resistant non-peptide motilin receptor agonist, in smooth muscle of rabbit small intestine.
Topics: Acetylcholine; Animals; Atropine; Binding, Competitive; Calcium Chloride; Diltiazem; Dose-Response Relationship, Drug; Erythromycin; Hexamethonium; Hydrogen-Ion Concentration; In Vitro Techniques; Indoles; Intestine, Small; Male; Molecular Structure; Muscle Contraction; Muscle, Smooth; Naloxone; Rabbits; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Tetrodotoxin; Tropisetron; Verapamil | 2007 |
Hemodynamic effects of intravenous fat emulsion in an animal model of severe verapamil toxicity resuscitated with atropine, calcium, and saline.
Topics: Animals; Atropine; Blood Pressure; Calcium Channel Blockers; Calcium Chloride; Cardiac Output; Dogs; Fat Emulsions, Intravenous; Heart Rate; Male; Parasympatholytics; Resuscitation; Sodium Chloride; Verapamil | 2007 |
Antimuscarinic drug inhibits detrusor overactivity induced by topical application of prostaglandin E2 to the urethra with a decrease in urethral pressure.
Topics: Administration, Intravesical; Administration, Topical; Adrenergic alpha-Antagonists; Animals; Atropine; Benzilates; Calcium Channel Blockers; Cholinergic Antagonists; Dinoprostone; Disease Models, Animal; Female; Injections, Intra-Arterial; Muscarinic Antagonists; Muscle Contraction; omega-Conotoxins; Oxytocics; Pressure; Rats; Rats, Sprague-Dawley; Sulfonamides; Tamsulosin; Treatment Outcome; Urethra; Urinary Bladder; Urinary Bladder, Overactive; Verapamil | 2007 |
Muscarinic, Ca(++) antagonist and specific butyrylcholinesterase inhibitory activity of dried ginger extract might explain its use in dementia.
Topics: Acetylcholine; Alzheimer Disease; Animals; Atropine; Butyrylcholinesterase; Calcium; Calcium Channel Blockers; Catechols; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Fatty Alcohols; Gastric Fundus; In Vitro Techniques; Molecular Structure; Muscarinic Agonists; Parasympatholytics; Physostigmine; Plant Extracts; Rats; Rats, Sprague-Dawley; Rhizome; Verapamil; Zingiber officinale | 2008 |
Uterine relaxant effects of Curcuma aeruginosa Roxb. rhizome extracts.
Topics: Acetylcholine; Animals; Atropine; Calcium Channel Blockers; Curcuma; Diclofenac; Dinoprost; Female; Isoproterenol; Oxytocics; Oxytocin; Parasympatholytics; Plant Extracts; Propranolol; Rats; Rats, Wistar; Rhizome; Uterine Contraction; Uterus; Vasodilator Agents; Verapamil | 2009 |
Blood pressure-lowering and vascular modulator effects of Acorus calamus extract are mediated through multiple pathways.
Topics: Acetylcholine; Acorus; Animals; Aorta, Thoracic; Atropine; Blood Pressure; Caffeine; Dose-Response Relationship, Drug; Egtazic Acid; Endothelium, Vascular; Indomethacin; Inhibitory Concentration 50; Male; NG-Nitroarginine Methyl Ester; Norepinephrine; Phenylephrine; Plant Extracts; Plant Roots; Potassium Chloride; Rats; Rats, Sprague-Dawley; Reference Standards; Ryanodine; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Verapamil | 2009 |
Red tide toxin produces in vitro depolarization of human airway smooth muscle.
Topics: Acetylcholine; Adult; Asthma; Atropine; Bronchoconstriction; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Male; Marine Toxins; Membrane Potentials; Microelectrodes; Muscle, Smooth; Tetrodotoxin; Verapamil; Young Adult | 2010 |
Bronchodilatory effect of Acorus calamus (Linn.) is mediated through multiple pathways.
Topics: Acorus; Animals; Atropine; Bronchodilator Agents; Calcium Channel Blockers; Carbachol; Female; Guinea Pigs; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth; Papaverine; Phosphodiesterase 4 Inhibitors; Plant Extracts; Potassium; Rhizome; Rolipram; Trachea; Verapamil | 2010 |
In vitro determination of the mechanism of the uterine stimulatory effect of Newbouldia laevis.
Topics: Adrenergic alpha-Antagonists; Animals; Atropine; Bignoniaceae; Calcium Channel Blockers; Diphenhydramine; Drug Evaluation, Preclinical; Female; Histamine H1 Antagonists; In Vitro Techniques; Muscarinic Antagonists; Oxytocics; Oxytocin; Phentolamine; Plant Extracts; Plant Leaves; Rats; Rats, Sprague-Dawley; Uterine Contraction; Verapamil | 2010 |
Role of taurine on acid secretion in the rat stomach.
Topics: Animals; Atropine; Bicuculline; Calcium; Calcium Channel Blockers; Cyclic AMP; Dose-Response Relationship, Drug; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Gastric Acid; Gastric Mucosa; Male; Muscarinic Antagonists; Rats; Rats, Sprague-Dawley; Signal Transduction; Taurine; Verapamil | 2011 |
Spasmogenic and spasmolytic activities of Onosma griffithii Vatke.
Topics: Acetylcholine; Animals; Atropine; Boraginaceae; Calcium Channel Blockers; Calcium Channels; Calcium Chloride; In Vitro Techniques; Jejunum; Methanol; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Parasympathomimetics; Plant Extracts; Potassium Chloride; Rabbits; Solvents; Verapamil | 2011 |
Activation of M3 muscarinic receptor and Ca²⁺ influx by crude fraction from Crotonis Fructus in isolated rabbit jejunum.
Topics: Animals; Atropine; Calcium; Calcium Channel Blockers; Croton; Female; Fruit; In Vitro Techniques; Jejunum; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Plant Extracts; Rabbits; Receptor, Muscarinic M3; Solvents; Verapamil | 2012 |
Prejunctional facilitatory effect of a thiol-alkylating agent N-Ethylmaleimide on neurogenic contractions in rat prostate smooth muscle.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Atropine; Calcium Channel Blockers; Electric Stimulation; Enzyme Inhibitors; Ethylmaleimide; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Nitroarginine; Prazosin; Prostate; Rats; Rats, Wistar; Suramin; Verapamil | 2012 |
Anthelmintic and relaxant activities of Verbascum Thapsus Mullein.
Topics: Albendazole; Animals; Anthelmintics; Ascaridia; Atropine; Cestoda; Helminthiasis, Animal; Helminths; Jejunum; Muscle Contraction; Muscle, Smooth; Paralysis; Parasympatholytics; Plant Extracts; Potassium Chloride; Rabbits; Spasm; Vasodilator Agents; Verapamil; Verbascum | 2012 |
Hypotensive effect of Gentiana floribunda is mediated through Ca++ antagonism pathway.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Arginine; Atropine; Blood Pressure; Calcium; Cardiovascular Agents; Dose-Response Relationship, Drug; Endothelium, Vascular; Gentiana; Hypertension; Indomethacin; Male; Phenylephrine; Phytotherapy; Plant Extracts; Potassium; Rats; Rats, Sprague-Dawley; Signal Transduction; Vasoconstriction; Vasodilator Agents; Verapamil | 2012 |
Verapamil reverses myocardial no-reflow after primary percutaneous coronary intervention in patients with acute myocardial infarction.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Atropine; Bradycardia; Coronary Angiography; Female; Humans; Hypotension; Incidence; Male; Middle Aged; Myocardial Infarction; No-Reflow Phenomenon; Percutaneous Coronary Intervention; Retrospective Studies; Stents; Treatment Outcome; Vasodilator Agents; Verapamil | 2013 |
Effects of berberine on rat jejunal motility.
Topics: Adrenergic Agents; Animals; Arginine; Atropine; Berberine; Berberis; Calcium; Cholinergic Agents; Enteric Nervous System; Gastrointestinal Motility; Irritable Bowel Syndrome; Jejunum; Muscle Contraction; Myosin-Light-Chain Kinase; Myosins; Phosphorylation; Phytotherapy; Plant Extracts; Propranolol; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetrodotoxin; Verapamil | 2013 |
Electrophysiological, vasoactive, and gastromodulatory effects of stevia in healthy Wistar rats.
Topics: Action Potentials; Animals; Aorta, Thoracic; Arrhythmias, Cardiac; Atropine; Calcium Channel Blockers; Humans; Ileum; Male; Mesenteric Arteries; Muscle, Smooth; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide; Plant Preparations; Plants, Medicinal; Rats; Rats, Wistar; Receptor, Muscarinic M2; Stevia; Vasodilator Agents; Verapamil | 2013 |
Characteristics of nobiletin-induced effects on jejunal contractility.
Topics: Animals; Atropine; Calcium; Calcium Channel Blockers; Enteric Nervous System; Enzyme Inhibitors; Female; Flavones; Gastrointestinal Motility; Gene Expression Regulation, Enzymologic; Jejunum; Male; Muscarinic Antagonists; Muscle Contraction; Myosin-Light-Chain Kinase; Myosins; Phosphorylation; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Verapamil | 2014 |
Modulatory effects of taurine on jejunal contractility.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Calcium Channel Blockers; Cimetidine; Diphenhydramine; Enteric Nervous System; Histamine H1 Antagonists; Histamine H2 Antagonists; Jejunum; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Myosin-Light-Chain Kinase; Myosins; Nitric Oxide; Nitric Oxide Synthase; Phentolamine; Phosphorylation; Propranolol; Rats, Sprague-Dawley; Taurine; Tetrodotoxin; Verapamil | 2014 |
Pharmacological Properties of Propiverine Contribute to Improving Lower Urinary Tract Dysfunctions in Rats with Spinal Cord Injuries.
Topics: Animals; Atropine; Benzilates; Capsaicin; Female; Muscarinic Antagonists; Rats; Spinal Cord Injuries; Urinary Bladder; Urinary Bladder, Overactive; Verapamil | 2016 |
Cardiac and extracardiac side effects of eye drops.
Topics: Adrenergic beta-Antagonists; Atropine; Bradycardia; Carteolol; Female; Heart Diseases; Humans; Ophthalmic Solutions; Timolol; Verapamil | 2021 |