Page last updated: 2024-09-05

atropine and tropisetron

atropine has been researched along with tropisetron in 23 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(tropisetron)
Trials
(tropisetron)
Recent Studies (post-2010) (tropisetron)
26,7111,2591,697944218150

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)tropisetron (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)3.1623
Muscarinic acetylcholine receptor M2Homo sapiens (human)3.1623
Muscarinic acetylcholine receptor M5Homo sapiens (human)3.45
Neuronal acetylcholine receptor subunit beta-4Homo sapiens (human)1.8
Sodium-dependent serotonin transporterHomo sapiens (human)0.488
Neuronal acetylcholine receptor subunit alpha-3Homo sapiens (human)1.8

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19903 (13.04)18.7374
1990's11 (47.83)18.2507
2000's7 (30.43)29.6817
2010's2 (8.70)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Dhasmana, KM; Saxena, PR; Tadipatri, S; Villalón, CM; Zhu, YN1
Harf, A; Istin, N; Jarreau, PH; Macquin-Mavier, I1
Ando, M; Mori, Y1
Hyman, PE; Jing, J; Ng, WW; Snape, WJ1
Chen, HI1
Buchheit, KH; Engel, G; Mutschler, E; Richardson, B1
Blauw, GJ; van Brummelen, P; van Zwieten, PA1
Blauw, GJ; Chang, PC; van Brummelen, P; van Zwieten, PA; Vermeij, P1
Buchheit, KH; Buhl, T1
Mizutani, M; Neya, T; Yamasato, T1
Hansen, MB1
de Ridder, WJ; Schuurkes, JA1
Gidener, S; Güven, H; Kirkali, Z1
Betz, H; Laube, B; Maksay, G1
Kollias-Baker, C; Nieto, JE; Snyder, JR; Stanley, S1
Naylor, RJ; Tuladhar, BR; Womack, MD1
Hayakawa, T; Ishige, A; Kase, Y; Kurosawa, S; Nakamura, T; Nishikawa, S; Sasaki, H; Satoh, K; Yakabi, K1
Brown, DR; Casey, MA; Townsend, D1
Itoh, Z; Koga, H; Omura, S; Ozaki, K; Takanashi, H; Yogo, K1
Bauer, K; Klaes, M; Ploch, M; Schmidt, T; Verspohl, EJ; Windeck, T1
Barreiro, EJ; Barrès, C; de Araújo Júnior, JX; de Medeiros, IA; Julien, C; Lima, LM; Ribeiro, EA1
Fujita, T; Kumamoto, E; Liu, T1

Trials

1 trial(s) available for atropine and tropisetron

ArticleYear
5HT3 receptor-mediated vasodilation in the human forearm.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1988, Volume: 6, Issue:4

    Topics: Acetylcholine; Adult; Arm; Atropine; Blood Pressure; Heart Rate; Humans; Indoles; Male; Receptors, Serotonin; Regional Blood Flow; Serotonin; Time Factors; Tropisetron; Vasodilation

1988

Other Studies

22 other study(ies) available for atropine and tropisetron

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Role of 5-HT1-like receptors in the increase in intragastric pressure induced by 5-hydroxytryptamine in the rat.
    European journal of pharmacology, 1992, Mar-24, Volume: 213, Issue:2

    Topics: Animals; Atropine; Catecholamines; Female; Indoles; Ketanserin; Male; Methiothepin; Methysergide; Pressure; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Stomach; Tropisetron

1992
5-Hydroxytryptamine-induced bronchoconstriction in the guinea-pig: effect of 5-HT2 receptor activation on acetylcholine release.
    British journal of pharmacology, 1991, Volume: 102, Issue:4

    Topics: Acetylcholine; alpha-Methyltyrosine; Animals; Atropine; Bronchoconstriction; Guinea Pigs; Hexamethonium Compounds; In Vitro Techniques; Indoles; Ketanserin; Male; Methyltyrosines; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tropisetron; Vagotomy

1991
Regulation of ion and water transport across the eel intestine: effects of acetylcholine and serotonin.
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 1991, Volume: 161, Issue:4

    Topics: Acetylcholine; Anguilla; Animals; Atropine; Biological Transport, Active; Electric Stimulation; Epithelium; Indoles; Intestinal Mucosa; Intestines; Ions; Membrane Potentials; Receptors, Muscarinic; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tropisetron; Water

1991
Effect of 5-hydroxytryptamine and its antagonists on colonic smooth muscle of the rabbit.
    Digestive diseases and sciences, 1991, Volume: 36, Issue:2

    Topics: Animals; Atropine; Colon; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Indoles; Ketanserin; Male; Methysergide; Muscle Contraction; Muscle, Smooth; Rabbits; Serotonin; Serotonin Antagonists; Tetrodotoxin; Tropisetron

1991
Evidence for the presynaptic action of 5-hydroxytryptamine and the involvement of purinergic innervation in the rabbit lower urinary tract.
    British journal of pharmacology, 1990, Volume: 101, Issue:1

    Topics: Adenosine Triphosphate; Animals; Atropine; Electric Stimulation; Female; Granisetron; In Vitro Techniques; Indazoles; Indoles; Male; Muscle Contraction; Muscle, Smooth; Purines; Rabbits; Serotonin; Serotonin Antagonists; Synapses; Tropanes; Tropisetron; Urethra; Urinary Tract

1990
Study of the contractile effect of 5-hydroxytryptamine (5-HT) in the isolated longitudinal muscle strip from guinea-pig ileum. Evidence for two distinct release mechanisms.
    Naunyn-Schmiedeberg's archives of pharmacology, 1985, Volume: 329, Issue:1

    Topics: Animals; Atropine; Capsaicin; Guinea Pigs; Ileum; In Vitro Techniques; Indoles; Male; Methysergide; Morphine; Muscle Contraction; Muscle, Smooth; Peptide Fragments; Physostigmine; Serotonin; Serotonin Antagonists; Substance P; Tetrodotoxin; Tropisetron

1985
Serotonin induced vasodilatation in the human forearm is antagonized by the selective 5-HT3 receptor antagonist ICS 205-930.
    Life sciences, 1988, Volume: 43, Issue:18

    Topics: Acetylcholine; Adult; Atropine; Cholinergic Fibers; Humans; Indoles; Infusions, Intra-Arterial; Male; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tropisetron; Vasodilation

1988
Stimulant effects of 5-hydroxytryptamine on guinea pig stomach preparations in vitro.
    European journal of pharmacology, 1994, Sep-01, Volume: 262, Issue:1-2

    Topics: 4-Aminobenzoic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Atropine; Benzamides; Binding Sites; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Indoles; Ligands; Male; Metoclopramide; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; para-Aminobenzoates; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Stomach; Tetrodotoxin; Tropanes; Tropisetron

1994
Role of 5-HT3 receptors in peristaltic reflex elicited by stroking the mucosa in the canine jejunum.
    The Journal of physiology, 1993, Volume: 471

    Topics: Animals; Atropine; Dogs; Female; Hexamethonium; Hexamethonium Compounds; Indoles; Intestinal Mucosa; Jejunum; Male; Neural Pathways; Nifedipine; Ondansetron; Peristalsis; Physical Stimulation; Receptors, Serotonin; Reflex; Serotonin Antagonists; Tetrodotoxin; Tropisetron

1993
ICS 205-930 reduces 5-methoxytryptamine-induced short-circuit current in stripped pig jejunum.
    Canadian journal of physiology and pharmacology, 1994, Volume: 72, Issue:3

    Topics: 5-Methoxytryptamine; Animals; Atropine; Bumetanide; Drug Interactions; Electrophysiology; Female; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Indoles; Jejunum; Kinetics; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Swine; Tetrodotoxin; Theophylline; Tropisetron

1994
Cisapride and 5-hydroxytryptamine enhance motility in the canine antrum via separate pathways, not involving 5-hydroxytryptamine1,2,3,4 receptors.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:1

    Topics: Animals; Atropine; Benzimidazoles; Cisapride; Dogs; Electric Stimulation; Gastrointestinal Motility; Hexamethonium; Hexamethonium Compounds; Histamine; In Vitro Techniques; Indoles; Muscle Contraction; Muscle, Smooth; Piperidines; Pyloric Antrum; Pyridines; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tetrodotoxin; Tropisetron

1993
Influence of serotonin on the human ureter: an in vitro pharmacological study.
    Urologia internationalis, 1995, Volume: 55, Issue:4

    Topics: Adult; Aged; Atropine; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Indoles; Ketanserin; Male; Methysergide; Middle Aged; Muscle Contraction; Serotonin; Serotonin Antagonists; Tropisetron; Ureter

1995
Selective blocking effects of tropisetron and atropine on recombinant glycine receptors.
    Journal of neurochemistry, 1999, Volume: 73, Issue:2

    Topics: Animals; Atropine; Chlorides; Dose-Response Relationship, Drug; Energy Transfer; Female; Humans; Indoles; Ion Channel Gating; Ionophores; Muscarinic Antagonists; Oocytes; Protein Structure, Tertiary; Receptors, Glycine; Recombinant Proteins; Serotonin Antagonists; Tropisetron; Xenopus laevis

1999
In vitro effects of 5-hydroxytryptamine and cisapride on the circular smooth muscle of the jejunum of horses.
    American journal of veterinary research, 2000, Volume: 61, Issue:12

    Topics: Animals; Atropine; Cisapride; Drug Synergism; Horses; In Vitro Techniques; Indoles; Isometric Contraction; Jejunum; Ketanserin; Muscle, Smooth; Serotonin; Serotonin Antagonists; Tetrodotoxin; Tropisetron

2000
Pharmacological characterization of the 5-HT receptor-mediated contraction in the mouse isolated ileum.
    British journal of pharmacology, 2000, Volume: 131, Issue:8

    Topics: Animals; Atropine; Dioxanes; Dose-Response Relationship, Drug; Female; Granisetron; Ileum; In Vitro Techniques; Indoles; Ketanserin; Male; Mice; Muscle Contraction; Ondansetron; Piperidines; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tetrodotoxin; Tropanes; Tropisetron

2000
Mechanisms for contractile effect of Dai-kenchu-to in isolated guinea pig ileum.
    Digestive diseases and sciences, 2001, Volume: 46, Issue:2

    Topics: Acetylcholine; Animals; Atropine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Gastrointestinal Motility; Guinea Pigs; Hexamethonium; Ileum; Indoles; Intestinal Pseudo-Obstruction; Male; Medicine, Kampo; Muscle Contraction; Muscle, Smooth; Nicotinic Antagonists; Panax; Parasympatholytics; Pharmaceutical Preparations; Plant Extracts; Serotonin Antagonists; Tetrodotoxin; Tropisetron; Zanthoxylum; Zingiberaceae

2001
Mediation of neurogenic ion transport by acetylcholine, prostanoids and 5-hydroxytryptamine in porcine ileum.
    European journal of pharmacology, 2005, Sep-20, Volume: 519, Issue:3

    Topics: 8,11,14-Eicosatrienoic Acid; Acetylcholine; Animals; Atropine; Electric Stimulation; Female; Ileum; In Vitro Techniques; Indoles; Indomethacin; Intestinal Mucosa; Ion Transport; Male; Prostaglandins; Saxitoxin; Serotonin; Serotonin Agents; Serotonin Antagonists; Swine; Tropisetron; Vasodilator Agents

2005
In vitro pharmacological characterization of mitemcinal (GM-611), the first acid-resistant non-peptide motilin receptor agonist, in smooth muscle of rabbit small intestine.
    Pharmacology, 2007, Volume: 79, Issue:3

    Topics: Acetylcholine; Animals; Atropine; Binding, Competitive; Calcium Chloride; Diltiazem; Dose-Response Relationship, Drug; Erythromycin; Hexamethonium; Hydrogen-Ion Concentration; In Vitro Techniques; Indoles; Intestine, Small; Male; Molecular Structure; Muscle Contraction; Muscle, Smooth; Naloxone; Rabbits; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Tetrodotoxin; Tropisetron; Verapamil

2007
Effect of two artichoke extracts (36_U and 36_EB) on rat ileum (with respect to bowel syndrome) and the peristaltic threshold.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2008, Volume: 15, Issue:11

    Topics: Animals; Atropine; Cinnamates; Cynara scolymus; Female; Flavones; Glucosides; Ileum; Indoles; Irritable Bowel Syndrome; Luteolin; Male; Muscle Contraction; Peristalsis; Plant Extracts; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tropisetron

2008
Cardiovascular effects of a novel synthetic analogue of naturally occurring piperamides.
    Journal of cardiovascular pharmacology, 2010, Volume: 56, Issue:3

    Topics: Animals; Apnea; Atropine; Benzodioxoles; Blood Pressure; Bradycardia; Capsaicin; Heart Rate; Hypotension; Indoles; Injections, Intravenous; Male; Morpholines; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Reflex; Ritanserin; Tropisetron; Vagotomy

2010
Acetylcholine and norepinephrine mediate GABAergic but not glycinergic transmission enhancement by melittin in adult rat substantia gelatinosa neurons.
    Journal of neurophysiology, 2011, Volume: 106, Issue:1

    Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Atropine; Carbachol; Dioxanes; gamma-Aminobutyric Acid; Glycine; Indoles; Inhibitory Postsynaptic Potentials; Male; Mecamylamine; Melitten; Muscarinic Antagonists; Neurons; Nicotine; Nicotinic Antagonists; Norepinephrine; Purinergic P2X Receptor Antagonists; Pyridoxal Phosphate; Rats; Serotonin Antagonists; Substantia Gelatinosa; Synaptic Transmission; Tropisetron

2011