atropine has been researched along with trihexyphenidyl in 71 studies
| Studies (atropine) | Trials (atropine) | Recent Studies (post-2010) (atropine) | Studies (trihexyphenidyl) | Trials (trihexyphenidyl) | Recent Studies (post-2010) (trihexyphenidyl) |
|---|---|---|---|---|---|
| 26,711 | 1,259 | 1,697 | 950 | 84 | 93 |
| Protein | Taxonomy | atropine (IC50) | trihexyphenidyl (IC50) |
|---|---|---|---|
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 0.034 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 0.0055 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 0.012 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 2.4498 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 0.0056 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 0.015 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.108 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 55 (77.46) | 18.7374 |
| 1990's | 7 (9.86) | 18.2507 |
| 2000's | 6 (8.45) | 29.6817 |
| 2010's | 3 (4.23) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Bhattacharjee, AK; Evans, SA; Gordon, RK; Pervitsky, D; Pomponio, JW | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Feldman, S; Putcha, L | 1 |
| Korf, J; Westerink, BH | 1 |
| Ivanova, EA | 1 |
| Dudar, JD | 1 |
| File, SE | 1 |
| Borsy, J; Dunai-Kovács, Z; Székely, JI | 1 |
| Boissier, JR; Simon, P; Soubrié, P | 1 |
| Algeri, S; Bonollo, L; Buniva, G; Cerletti, C; Curcio, M; Minazzi, M; Minoli, G; Morselli, PL | 1 |
| Bajgar, J; Fusek, J; Jakl, A; Patocka, J | 1 |
| Onodera, K; Shinoda, H | 1 |
| Anderson, DR; Harris, LW; Lennox, WJ; Solana, RP; Talbot, BG | 1 |
| Biziere, K; Jung, M; Perio, A; Worms, P | 1 |
| Ortegón, ME; Raffa, RB; Watson, M | 1 |
| Stojić, D; Terzić, M | 1 |
| Beleslin, DB; Samardzić, R; Stefanović-Denić, K | 1 |
| Anthoupoulou, E; Cavalla, D; Hadjiconstantinou, M; Laird, HE; Neff, NH | 1 |
| Beaujouan, JC; Glowinski, J; Guyenet, P; Lefresne, P; Rossier, J | 1 |
| Bianchi, C; Tomasi, L | 1 |
| Bowers, MB; Roth, RH | 1 |
| Nose, T; Segawa, T | 1 |
| Gressier, H; Malecot, E; Poignant, JC | 1 |
| Jurna, I; Lanzer, G | 1 |
| Bachmann, T; Jurna, I; Theres, C | 1 |
| Kojima, T; Omori, K | 1 |
| Brittain, RT | 1 |
| Carrano, RA; Malone, MH | 1 |
| Klawans, HL | 1 |
| Barlow, RB | 1 |
| Andén, NE; Bédard, P | 1 |
| Hitomi, M; Kumada, S; Kumadaki, N; Watanabe, N | 1 |
| Rodríguez, R | 1 |
| Furukawa, T; Hitomi, M; Ito, N; Kumada, S; Kumadaki, N; Sato, Y | 1 |
| Ahtee, L; Kääriäinen, I; Paasonen, MK | 1 |
| Clarke, G; Davies, J | 1 |
| Sethy, VH; Van Woert, MH | 1 |
| Vaillant, GE | 1 |
| Kojima, M; Nose, T; Shintomi, K; Yoneda, N | 1 |
| McCulloch, JA; Ursillo, RC | 1 |
| Frances, H; Jacob, J | 1 |
| Florio, V; Longo, VG | 1 |
| Madill, HD; Savoie, ML; Stewart, WC | 1 |
| Herz, A | 1 |
| Sabelli, HC; Toman, JE | 1 |
| Jenden, DJ; Lomax, P | 1 |
| Bartels, E; Rosenberg, P | 1 |
| Walther, H | 1 |
| Heathcote, BV; Parry, M | 1 |
| Chaudhuri, SK | 1 |
| Caviglia, A; Cellitti, M; Di Bianco, V; Di Castro, A; Pavoncello, S | 1 |
| Mitchelson, F; Shen, A | 1 |
| McDonough, JH; Shih, TM | 1 |
| Grauer, E; Kapon, J | 1 |
| Kassa, J | 2 |
| Kassa, J; Krejcová, G | 1 |
| Dagaev, SG; Dolgo-Saburov, VB; Fil'ko, OA; Khrabrova, AV; Kosmachev, AB; Kubarskaya, LG; Libman, NM; Sanotskii, VI | 1 |
| LANDS, AM; LUDUENA, FP | 1 |
| BAKER, N | 1 |
| BOFF, E; SCHECKEL, CL | 1 |
| LESLIE, GB; MAXWELL, DR | 1 |
| DRAPER, IT; JOHNS, RJ | 1 |
| BIGNAMI, G; BOVET, D; ROBUSTELLI, F | 1 |
| ARZT, FC; BRAGAN, RA; DECATO, L; MALONE, MH | 1 |
| Kassa, J; Krejcová, G; Samnaliev, I | 1 |
| HEYMANS, C; HYDE, JE; TERP, P | 1 |
| Andrade, C; Bambole, V; Bang, A; Shah, N; Sonavane, S | 1 |
2 review(s) available for atropine and trihexyphenidyl
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
The pharmacology of parkinsonism (a review).
Topics: Acetylcholine; Animals; Atropa belladonna; Atropine; Central Nervous System; Chlorpromazine; Dextroamphetamine; Dihydroxyphenylalanine; Diphenhydramine; Dopa Decarboxylase; Dopamine; Drug Synergism; Epinephrine; Haloperidol; Histamine H1 Antagonists; Humans; Mice; Monoamine Oxidase; Norepinephrine; Parkinson Disease; Parkinson Disease, Secondary; Peripheral Nerves; Phytotherapy; Plants, Medicinal; Plants, Toxic; Reserpine; Trihexyphenidyl | 1968 |
69 other study(ies) available for atropine and trihexyphenidyl
| Article | Year |
|---|---|
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Discovery of subtype selective muscarinic receptor antagonists as alternatives to atropine using in silico pharmacophore modeling and virtual screening methods.
Topics: Atropine; Computer Simulation; Drug Discovery; Humans; Models, Molecular; Molecular Structure; Receptor, Muscarinic M1; Structure-Activity Relationship | 2013 |
Effect of anti-parkinsonism drugs on gastric emptying and intestinal transit in the rat.
Topics: Administration, Oral; Animals; Antiparkinson Agents; Atropine; Benztropine; Diphenhydramine; Gastric Emptying; Gastrointestinal Motility; Injections, Intraperitoneal; Male; Parasympatholytics; Phenolsulfonphthalein; Phenothiazines; Rats; Trihexyphenidyl | 1977 |
Influence of drugs on striatal and limbic homovanillic acid concentration in the rat brain.
Topics: Aminooxyacetic Acid; Animals; Atropine; Brain; Brain Chemistry; Clozapine; Corpus Striatum; Fenclonine; Haloperidol; Homovanillic Acid; Limbic System; Male; Morphine; Oxotremorine; Phenylacetates; Physostigmine; Pimozide; Probenecid; Rats; Substantia Nigra; Trihexyphenidyl | 1975 |
[Effect of various mixtures of anticholinergic agents on the functional state of the circulatory system in peptic ulcer].
Topics: Adolescent; Adult; Atropine; Blood Pressure; Drug Combinations; Female; Heart; Humans; Male; Middle Aged; Papaverine; Peptic Ulcer; Trihexyphenidyl | 1977 |
The role of the septal nuclei in the release of acetyl-choline from the rabbit cerebral cortex and dorsal hippocampus and the effect of atropine.
Topics: Acetylcholine; Animals; Atropine; Cerebral Cortex; Electric Stimulation; Female; Hippocampus; Male; Mesencephalon; Neural Pathways; Rabbits; Reticular Formation; Septal Nuclei; Septum Pellucidum; Trihexyphenidyl | 1977 |
Are central cholinergic paths involved in habituation of exploration and distraction?
Topics: Acoustic Stimulation; Animals; Atropine; Attention; Exploratory Behavior; Habituation, Psychophysiologic; Male; Mice; Mice, Inbred Strains; Rats; Scopolamine; Sympathetic Nervous System; Time Factors; Trihexyphenidyl | 1976 |
The effect of anti-parkinsonian drugs on chlorpromazine-induced depression of operant behaviour.
Topics: Amantadine; Animals; Antiparkinson Agents; Apomorphine; Atropine; Behavior, Animal; Chlorpromazine; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Phenothiazines; Rats; Trihexyphenidyl | 1976 |
Antagonism of diazepam against central anticholinergic drug-induced hyperactivity in mice: involvement of a GABA mechanism.
Topics: Aminobutyrates; Animals; Atropine; Benztropine; Diazepam; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred Strains; Motor Activity; Parasympatholytics; Picrotoxin; Scopolamine; Semicarbazides; Strychnine; Trihexyphenidyl | 1976 |
Effect of anticholinergic drugs on gastro-intestinal absorption of L-dopa in rats and in man.
Topics: Administration, Oral; Adult; Aged; Animals; Atropine; Digestive System; Drug Interactions; Female; Humans; Injections, Intraperitoneal; Intestinal Absorption; Levodopa; Male; Middle Aged; Parasympatholytics; Parkinson Disease; Rats; Time Factors; Trihexyphenidyl | 1976 |
Efficacy of various pretreatment and therapy regimens against soman lethality in mice.
Topics: Animals; Atropine; Diazepam; Female; Male; Mice; Obidoxime Chloride; Poisoning; Pyridostigmine Bromide; Soman; Trihexyphenidyl; Trimedoxime | 1991 |
Pharmacological characteristics of catalepsy induced by intracerebroventricular administration of histamine in mice: the importance of muscarinic step in central cholinergic neurons.
Topics: Amantadine; Animals; Atropine; Biperiden; Bromocriptine; Catalepsy; Histamine; Injections, Intraventricular; Levodopa; Male; Mice; Neurons; Promethazine; Receptors, Muscarinic; Scopolamine; Trihexyphenidyl | 1991 |
Physostigmine (alone and together with adjunct) pretreatment against soman, sarin, tabun and VX intoxication.
Topics: Animals; Atropine; Benztropine; Cholinesterase Inhibitors; Female; Guinea Pigs; Lethal Dose 50; Male; Organophosphates; Organothiophosphorus Compounds; Physostigmine; Sarin; Soman; Trihexyphenidyl | 1991 |
Characterization of the scopolamine stimulus in rats.
Topics: Animals; Atropine; Conditioning, Operant; Cues; Discrimination, Psychological; Dose-Response Relationship, Drug; Food; Generalization, Psychological; Male; Parasympatholytics; Rats; Scopolamine; Time Factors; Trihexyphenidyl | 1988 |
Reciprocal hindlimb scratching and putative subtype-selective muscarinic agents.
Topics: Animals; Atropine; Binding Sites; Diamines; Dose-Response Relationship, Drug; Drug Antagonism; Hindlimb; Injections, Spinal; Male; Mice; Parasympathomimetics; Pilocarpine; Receptors, Muscarinic; Succinimides; Trihexyphenidyl | 1988 |
Oxygen consumption mediated by M2 muscarinic receptors in rat salivary glands.
Topics: Animals; Atropine; Carbachol; Dose-Response Relationship, Drug; Female; Male; Nifedipine; Oxotremorine; Oxygen Consumption; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Salivary Glands; Trihexyphenidyl | 1987 |
Comparative behavioral effects of anticholinergic agents in cats: psychomotor stimulation and aggression.
Topics: Aggression; Animals; Atropine; Autonomic Nervous System; Carbachol; Cats; Dose-Response Relationship, Drug; Female; Injections, Intraventricular; Male; Motor Activity; Parasympatholytics; Physostigmine; Scopolamine; Seizures; Trihexyphenidyl; Vocalization, Animal | 1986 |
N-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine increases acetylcholine and decreases dopamine in mouse striatum: both responses are blocked by anticholinergic drugs.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Acetylcholine; Animals; Atropine; Corpus Striatum; Dopamine; Male; Mice; Parasympatholytics; Pyridines; Trihexyphenidyl | 1985 |
Effect of sodium, hemicholinium-3 and antiparkinson drugs on (14C)acetylcholine synthesis and (3H)choline uptake in rat striatal synaptosomes.
Topics: Acetylcholine; Animals; Antiparkinson Agents; Atropine; Benztropine; Carbon Radioisotopes; Choline; Corpus Striatum; Dose-Response Relationship, Drug; Glucose; Hemicholinium 3; Phenothiazines; Pyruvates; Rats; Sodium; Synaptosomes; Trihexyphenidyl | 1973 |
Central nervous system and autonomic nervous system effects of amantadine and of some standard anti-Parkinson drugs.
Topics: Amantadine; Animals; Antiparkinson Agents; Atropine; Autonomic Nervous System; Body Temperature; Carbachol; Central Nervous System; Dihydroxyphenylalanine; Drug Interactions; Gastrointestinal Motility; Male; Mecamylamine; Mice; Mydriatics; Nicotine; Oxotremorine; Phenothiazines; Pupil; Rats; Trihexyphenidyl | 1973 |
Interaction of atropine-like drugs with dopamine-containing neurones in rat brain.
Topics: Animals; Atropine; Benztropine; Brain; Chlorpromazine; Dopamine; Homovanillic Acid; Male; Methyltyrosines; Neurons; Orphenadrine; Phenothiazines; Procyclidine; Rats; Time Factors; Trihexyphenidyl | 1972 |
A comparison of the inhibitory effects of certain antiparkinsonian agents on dopamine accumulation into the rat striatum.
Topics: Animals; Antidepressive Agents; Antiparkinson Agents; Atropine; Benztropine; Chlorpromazine; Corpus Striatum; Diphenhydramine; Dopamine; Glycolates; Male; Mitochondria; Ouabain; Phenothiazines; Rats; Trihexyphenidyl | 1974 |
Comparative effects of apomorphine, piribedil and other neurotropic agents on central analgesic-induced catatonia in the rat.
Topics: Amantadine; Analgesics, Opioid; Animals; Antiparkinson Agents; Apomorphine; Atropine; Benserazide; Benzyl Compounds; Catatonia; Dextroamphetamine; Dextromoramide; Dihydroxyphenylalanine; Dioxoles; Dose-Response Relationship, Drug; Humans; Male; Morphine; Piperazines; Pyrimidines; Rats; Time Factors; Trihexyphenidyl | 1974 |
Inhibition of the effect of reserpine on motor control by drugs which influence reserpine rigidity.
Topics: 1-Propanol; Animals; Atropine; Biperiden; Cyclohexanes; Cyclopentanes; Depression, Chemical; Dihydroxyphenylalanine; Methamphetamine; Motor Activity; Motor Neurons; Movement Disorders; Parasympathomimetics; Phenytoin; Piperidines; Rats; Reserpine; Spinal Cord; Sympathomimetics; Trihexyphenidyl | 1969 |
The effect of physostigmine and tetrabenazine on spinal motor control and its inhibition by drugs which influence reserpine rigidity.
Topics: 1-Propanol; Animals; Atropine; Biperiden; Dihydroxyphenylalanine; Electric Stimulation; Electromyography; Methamphetamine; Motor Neurons; Movement Disorders; Parasympatholytics; Phenytoin; Physostigmine; Piperidines; Rats; Reserpine; Spinal Cord; Spinal Nerves; Tetrabenazine; Trihexyphenidyl | 1969 |
Effect of L-5HTP on tremorine- or oxotremorine-induced tremor in mice and rats.
Topics: 5-Hydroxytryptophan; Animals; Atropine; Drug Synergism; Fenclonine; Male; Mice; Oxotremorine; Rats; Scopolamine; Tremor; Tremorine; Trihexyphenidyl; Tropanes | 1973 |
The intracerebral effects of noradrenaline and its modification by drugs in the mouse.
Topics: Amitriptyline; Animals; Antidepressive Agents; Ataxia; Atropine; Body Temperature; Brain; Central Nervous System; Chlordiazepoxide; Chlorpheniramine; Chlorpromazine; Diazepam; Drug Antagonism; Haloperidol; Histamine H1 Antagonists; Imipramine; Male; Mice; Norepinephrine; Nortriptyline; Pentobarbital; Phenytoin; Piperazines; Trihexyphenidyl | 1966 |
Anticholinergic evaluation of 1,1-diphenyl-2-(1-methyl-3-pyrrolidyl) ethanol and N-(2'5'-dimethyl-1'-piperidylmethyl) benzilamide.
Topics: Animals; Atropine; Diphenylacetic Acids; Drug Antagonism; In Vitro Techniques; Jejunum; Papaverine; Parasympatholytics; Rats; Scopolamine; Sensory Receptor Cells; Trihexyphenidyl | 1966 |
Differences in the stereospecificity of closely related compounds; a reinvestigation of the enantiomers of procyclidine, benzhexol and their metho- and etho-salts.
Topics: 1-Propanol; Acetylcholine; Animals; Atropine; Biological Assay; Guinea Pigs; Ileum; In Vitro Techniques; Parasympatholytics; Polarography; Procyclidine; Pyrrolidines; Receptors, Drug; Stereoisomerism; Trihexyphenidyl | 1971 |
Influences of cholinergic mechanisms on the function and turnover of brain dopamine.
Topics: Animals; Apomorphine; Atropine; Basal Ganglia; Brain; Catalepsy; Cyclopentanes; Dopamine; Hallucinogens; Haloperidol; Humans; Mandelic Acids; Norepinephrine; Parasympatholytics; Piperidines; Rats; Scopolamine; Trihexyphenidyl | 1971 |
Pharmacological study of piroheptine, a new antiparkinson drug. II. Anticholinergic, antihistaminic, and psychopharmacological actions and toxicity.
Topics: Animals; Antiparkinson Agents; Atropine; Central Nervous System; Dogs; Female; Fetus; Gastric Juice; Gastrointestinal Motility; Guinea Pigs; Histamine H1 Antagonists; Male; Mice; Mice, Inbred Strains; Mydriatics; Parasympatholytics; Promethazine; Pyrrolidines; Rats; Rats, Inbred Strains; Trihexyphenidyl | 1972 |
Antagonism of tremorine-induced tremor by serotoninergic agents in mice. Interactions with levodopa.
Topics: 5-Hydroxytryptophan; Animals; Atropine; Benztropine; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Male; Mice; Mice, Inbred Strains; Oxotremorine; Piperazines; Quinolines; Serotonin; Tremor; Tremorine; Trihexyphenidyl | 1972 |
Pharmacological study of piroheptine, a new antiparkinson drug, 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-ethyl-2-methylpyrrolidine. I. Effects on drug-induced tremor and catatonia, and on adrenergic actions.
Topics: Animals; Antiparkinson Agents; Atropine; Avoidance Learning; Catatonia; Cats; Conditioning, Psychological; Haplorhini; Humans; Macaca; Male; Mice; Mice, Inbred Strains; Motor Activity; Nictitating Membrane; Parasympatholytics; Promethazine; Pyrrolidines; Rats; Rats, Inbred Strains; Tremor; Trihexyphenidyl | 1972 |
Effect of nalorphine and antiparkinsonian drugs on methadone-induced rigidity; relation to homovanillic acid content of nucleus caudatus.
Topics: Amantadine; Animals; Atropine; Body Temperature; Brain; Caudate Nucleus; Depression, Chemical; Dose-Response Relationship, Drug; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Methadone; Muscle Rigidity; Muscle Tonus; Nalorphine; Parasympatholytics; Phenylacetates; Rats; Serotonin; Spectrometry, Fluorescence; Trihexyphenidyl | 1972 |
The effects of anti-Parkinson drugs on cortical neurones.
Topics: Acetylcholine; Action Potentials; Anesthetics, Local; Animals; Antiparkinson Agents; Anura; Atropine; Benzilates; Blood Pressure; Body Temperature; Cats; Cerebral Cortex; Depression, Chemical; Electrocardiography; Electroencephalography; Ethylamines; Female; Glutamates; In Vitro Techniques; Iontophoresis; Male; Microelectrodes; Neurons; Procaine; Propylamines; Respiration; Sciatic Nerve; Trihexyphenidyl | 1973 |
Antimuscarinic drugs--effect on brain acetylcholine and tremors in rats.
Topics: Acetylcholine; Animals; Atropine; Benztropine; Brain Chemistry; Depression, Chemical; Drug Interactions; Male; Oxotremorine; Parasympatholytics; Physostigmine; Rats; Stimulation, Chemical; Time Factors; Tremor; Trihexyphenidyl | 1973 |
A comparison of antagonists of physostigmine-induced suppression of behavior.
Topics: Amphetamine; Animals; Atropine; Behavior, Animal; Chlorpromazine; Columbidae; Diphenhydramine; Haplorhini; Imipramine; Male; Mecamylamine; Muscles; Parasympatholytics; Physostigmine; Scopolamine; Trihexyphenidyl | 1967 |
Pharmacology of a new anti-parkinsonian drug: KAO-264.
Topics: Animals; Atropine; Catalepsy; Haloperidol; Haplorhini; Humans; Mydriatics; Parasympatholytics; Thiophenes; Trihexyphenidyl; Tropanes | 1971 |
The effect of elantrine, a new anti-Parkinsonism agent, on drug-induced tremor in mice.
Topics: Alkaloids; Animals; Antiparkinson Agents; Atropine; Benztropine; Body Temperature; Central Nervous System; Dibenzazepines; Drug Antagonism; Indoles; Male; Methylamines; Mice; Nicotine; Oxotremorine; Parasympatholytics; Procyclidine; Pupil; Pyridines; Seizures; Tremor; Trihexyphenidyl | 1972 |
[Comparison of the effects of cholinergic and anticholinergic substances on the cerebral content of acetylcholine and on the motility of mice].
Topics: Acetylcholine; Amphetamine; Animals; Atropine; Benactyzine; Brain Chemistry; Glycolates; Imipramine; Male; Mice; Motor Activity; Nicotinic Acids; Parasympatholytics; Parasympathomimetics; Physostigmine; Quinuclidines; Scopolamine; Tremor; Trihexyphenidyl | 1971 |
Effects of amantadine and of some synthetic antiparkinsonian drugs on the behavioral response to L-DOPA in mice.
Topics: Amantadine; Amitriptyline; Animals; Antiparkinson Agents; Atropine; Behavior, Animal; Dihydroxyphenylalanine; Diphenhydramine; Drug Synergism; Imipramine; Mice; Orphenadrine; Parasympatholytics; Pargyline; Trihexyphenidyl | 1971 |
Central and peripheral anticholinergic potency of some drugs antagonistic to anticholinesterase poisoning.
Topics: Animals; Antidotes; Atropine; Bradycardia; Carbachol; Central Nervous System; Cholinesterase Inhibitors; Female; Guinea Pigs; Hallucinogens; Heart Rate; Mandelic Acids; Methacholine Compounds; Mice; Parasympatholytics; Peripheral Nerves; Phosphates; Piperidines; Pupil; Quaternary Ammonium Compounds; Rabbits; Scopolamine; Seizures; Trihexyphenidyl | 1968 |
Some actions of cholinergic and anticholinergic drugs on reactive behavior.
Topics: Animals; Atropine; Avoidance Learning; Benactyzine; Chlorpromazine; Cholinesterase Inhibitors; Conditioning, Psychological; Dextroamphetamine; Mice; Morphine; Nicotinic Acids; Pyrrolidines; Scopolamine; Spiro Compounds; Tremorine; Trihexyphenidyl | 1968 |
Neuropharmacology of earthworm giant fibers.
Topics: Action Potentials; Animals; Annelida; Anura; Atropine; Calcium Chloride; Chlordiazepoxide; Diazepam; Lysergic Acid Diethylamide; Methamphetamine; Neural Conduction; Neurons; Opipramol; Phenothiazines; Physiology, Comparative; Potassium Chloride; Procaine; Rubidium; Sciatic Nerve; Scopolamine; Strychnine; Trihexyphenidyl; Tubocurarine; Urea; Veratrine | 1968 |
Antiparkinsonism drugs.
Topics: Antidepressive Agents; Atropine; Diphenhydramine; Humans; Orphenadrine; Parasympatholytics; Parkinson Disease; Promethazine; Scopolamine; Trihexyphenidyl | 1965 |
Hypothermia following systematic and intracerebral injection of oxotremorine in the rat.
Topics: Animals; Atropine; Body Temperature Regulation; Carbachol; Drug Antagonism; Female; Hypothalamus; Hypothermia; Injections, Intraperitoneal; Injections, Intravenous; Rats; Tremorine; Trihexyphenidyl | 1966 |
Drug effects on the spontaneous electrical activity of the squid giant axon.
Topics: Acetylcholine; Action Potentials; Animals; Anticonvulsants; Atropine; Axons; Barbiturates; Bromides; Chloroform; Chlorpheniramine; Chlorpromazine; Curare; Dopamine; Electrophysiology; Ethanol; Ethers; Evoked Potentials; Hydantoins; Mollusca; Muscles; Nortropanes; Parasympatholytics; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Procaine; Serotonin; Strychnine; Tetracaine; Tremorine; Trihexyphenidyl; Trimethadione | 1967 |
[Pharmacologic studies of the strychnine tremor in infantile mice].
Topics: Animals; Animals, Newborn; Anticonvulsants; Atropine; Benactyzine; Diphenhydramine; Electromyography; Guaifenesin; Mice; Muscles; Neurons; Parasympatholytics; Phenobarbital; Piperidines; Propiophenones; Scopolamine; Spinal Cord; Strychnine; Tremor; Trihexyphenidyl | 1967 |
Pirenzepine selectively inhibits gastric acid secretion: a comparative pharmacological study between pirenzepine and seven other antiacetylcholine drugs.
Topics: Acetylcholine; Animals; Atropine; Benzilates; Benzodiazepinones; Dose-Response Relationship, Drug; Gastric Acid; Glycopyrrolate; Male; Mice; Piperazines; Pirenzepine; Propantheline; Pupil; Pyrimidines; Quaternary Ammonium Compounds; Rats; Trihexyphenidyl | 1980 |
Anticholinergic agents on neuromuscular and tremorogenic action of harmine.
Topics: Alkaloids; Animals; Atropine; Female; Harmine; Male; Neuromuscular Junction; Rats; Tremor; Trihexyphenidyl | 1980 |
[Neurological aspects and modern trends in therapy of Parkinson's disease].
Topics: Atropine; Biperiden; Humans; Levodopa; Parasympatholytics; Parkinson Disease; Procyclidine; Trihexyphenidyl | 1980 |
Characterization of the muscarine receptor subtype on sympathetic nerve endings in the rat caudal artery.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Arteries; Atropine; Bis-Trimethylammonium Compounds; Carbachol; Female; In Vitro Techniques; Isoindoles; Male; Muscarinic Antagonists; Muscle, Smooth, Vascular; Nerve Endings; Parasympatholytics; Piperidines; Rats; Rats, Wistar; Receptors, Muscarinic; Sympathetic Nervous System; Tail; Trihexyphenidyl | 1994 |
Pharmacological modulation of soman-induced seizures.
Topics: Animals; Anticonvulsants; Atropine; Behavior, Animal; Benactyzine; Diazepam; Dizocilpine Maleate; Electrodes, Implanted; Electroencephalography; Male; Rats; Rats, Sprague-Dawley; Seizures; Soman; Trihexyphenidyl | 1993 |
Differential effects of anticholinergic drugs on paired discrimination performance.
Topics: Animals; Atropine; Behavior, Animal; Benactyzine; Cholinergic Antagonists; Discrimination Learning; Discrimination, Psychological; Male; Maze Learning; Memory; Memory, Short-Term; Parasympatholytics; Rats; Rats, Sprague-Dawley; Scopolamine; Trihexyphenidyl | 1996 |
[The effect of pharmacologic prophylaxis with Panpal on acetylcholinesterase activity in the diaphragm and various parts of the brain in rats during treated and untreated Soman poisoning].
Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Benactyzine; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diaphragm; Drug Combinations; Male; Oximes; Poisoning; Pyridinium Compounds; Pyridostigmine Bromide; Rats; Rats, Wistar; Soman; Trihexyphenidyl | 1998 |
[The effect of panpal prophylaxis on acetylcholinesterase activity in the blood, diaphragm and various parts of the brain in rats during treated and untreated poisoning with the organophosphorus insecticide phosdrine]].
Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Benactyzine; Brain; Cholinesterase Reactivators; Diaphragm; Drug Combinations; Insecticides; Male; Mevinphos; Oximes; Pyridinium Compounds; Pyridostigmine Bromide; Rats; Rats, Wistar; Trihexyphenidyl | 2000 |
Neuroprotective efficacy of pharmacological pretreatment and antidotal treatment in tabun-poisoned rats.
Topics: Animals; Antidotes; Atropine; Behavior, Animal; Benactyzine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Drug Combinations; Drug Therapy, Combination; Lethal Dose 50; Male; Motor Activity; Nervous System Diseases; Neuroprotective Agents; Neuropsychological Tests; Obidoxime Chloride; Organophosphates; Pyridostigmine Bromide; Rats; Rats, Wistar; Trihexyphenidyl | 2003 |
Qualitative assessment of selective blockade of M(4)-cholinoreceptors in the whole organism.
Topics: Animals; Atropine; Dose-Response Relationship, Drug; Motor Activity; Muscarinic Agonists; Muscarinic Antagonists; Pilocarpine; Rats; Receptor, Muscarinic M4; Trihexyphenidyl; Tropanes | 2003 |
An investigation of the pharmacological actions of three potent antispasmodic compounds and their corresponding metho-salts.
Topics: Acetates; Atropine; Cardiovascular Agents; Muscle Relaxants, Central; Parasympatholytics; Salts; Trihexyphenidyl | 1954 |
SUPERSENSITIVITY TO ANTICHOLINESTERASES OF AN ISOLATED NERVE-MUSCLE PREPARATION FROM HEREDITARILY DYSTROPHIC MICE.
Topics: Animals; Atropine; Cholinesterase Inhibitors; Cholinesterases; Diphosphates; Enzyme Inhibitors; Mice; Muscular Dystrophies; Neostigmine; Neuromuscular Junction; Pharmacology; Physostigmine; Procaine; Research; Trihexyphenidyl; Tubocurarine | 1963 |
BEHAVIORAL EFFECTS OF INTERACTING IMIPRAMINE AND OTHER DRUGS WITH D-AMPHETAMINE, COCAINE, AND TETRABENAZINE.
Topics: Amitriptyline; Atropine; Avoidance Learning; Chlorpromazine; Cocaine; Desipramine; Dextroamphetamine; Guanethidine; Imipramine; Iproniazid; Isocarboxazid; Methylphenidate; Parasympatholytics; Pharmacology; Piperidines; Promazine; Promethazine; Rats; Research; Scopolamine; Tetrabenazine; Trihexyphenidyl; Tyramine | 1964 |
INHIBITION OF TREMORINE BY A GROUP OF NON-ANTI-PARKINSON PHENOTHIAZINE DERIVATIVES.
Topics: Antipsychotic Agents; Atropine; Benactyzine; Chlorpromazine; Histamine H1 Antagonists; Mice; Muscle Relaxants, Central; Parasympatholytics; Pharmacology; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Research; Scopolamine; Tranquilizing Agents; Tremor; Tremorine; Trihexyphenidyl | 1964 |
THE DISORDERED MOVEMENT IN PARKINSONISM AND THE EFFECT OF DRUG TREATMENT.
Topics: Atropine; Dextroamphetamine; Diphenhydramine; Drug Therapy; Geriatrics; Humans; Kinetics; Motor Skills; Movement Disorders; Orphenadrine; Parasympatholytics; Parkinsonian Disorders; Reaction Time; Trihexyphenidyl | 1964 |
[STUDY OF INHIBITOR CONDITIONING IN THE RAT. ACTION OF AMPHETAMINE, CHLORPROMAZINE AND CHOLINERGIC AGENTS].
Topics: Amphetamine; Amphetamines; Atropine; Avoidance Learning; Benactyzine; Chlorpromazine; Cholinergic Agents; Conditioning, Classical; Conditioning, Psychological; Parasympatholytics; Phenmetrazine; Physostigmine; Psychopharmacology; Rats; Research; Scopolamine; Trihexyphenidyl | 1965 |
RESERPINE-NICOTINE INDUCED PARKINSONISM IN MICE.
Topics: Anticonvulsants; Atropine; Lactose; Mice; Muscle Relaxants, Central; Neostigmine; Nicotine; Parkinsonian Disorders; Pharmacology; Phenobarbital; Research; Reserpine; Scopolamine; Tetraethylammonium Compounds; Toxicology; Trihexyphenidyl | 1965 |
A comparison of the neuroprotective efficacy of pharmacological pretreatment and antidotal treatment in soman-poisoned rats.
Topics: Animals; Antidotes; Atropine; Benactyzine; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Drug Combinations; Drug Therapy, Combination; Male; Neuroprotective Agents; Oximes; Premedication; Pyridinium Compounds; Pyridostigmine Bromide; Rats; Rats, Wistar; Soman; Trihexyphenidyl | 2003 |
Action of trihexylphenidyl (artane) and atropine on central synaptic transmission.
Topics: Atropine; Sympathetic Nervous System; Synaptic Transmission; Trihexyphenidyl | 1951 |
Continuation of ECT after recovery from transient, ECT-induced, postictal cortical blindness.
Topics: Adolescent; Anti-Dyskinesia Agents; Antipsychotic Agents; Atropine; Benzodiazepines; Blindness, Cortical; Electroconvulsive Therapy; Female; Glycopyrrolate; Haloperidol; Humans; Muscarinic Antagonists; Olanzapine; Panic; Schizophrenia, Paranoid; Treatment Outcome; Trihexyphenidyl | 2012 |