Page last updated: 2024-09-05

atropine and tretinoin

atropine has been researched along with tretinoin in 11 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(tretinoin)
Trials
(tretinoin)
Recent Studies (post-2010) (tretinoin)
26,7111,2591,69723,6541,0836,085

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)tretinoin (IC50)
Bile salt export pumpHomo sapiens (human)10
Amyloid-beta precursor proteinHomo sapiens (human)0.18
Adenosine receptor A3Homo sapiens (human)5.275
Retinoic acid receptor alphaHomo sapiens (human)2.2542
60 kDa heat shock protein, mitochondrialHomo sapiens (human)5.3
Retinoic acid receptor betaHomo sapiens (human)0.7537
Retinoic acid receptor alphaMus musculus (house mouse)0.0057
Retinoic acid receptor gamma Homo sapiens (human)0.0064
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)5.275
Retinoic acid receptor gammaMus musculus (house mouse)0.004
Retinoic acid receptor betaMus musculus (house mouse)0.005
Mitogen-activated protein kinase 1Homo sapiens (human)0.576
Nuclear receptor ROR-alphaHomo sapiens (human)0.1995
Alpha-synucleinHomo sapiens (human)3
Cellular retinoic acid-binding protein 1Gallus gallus (chicken)0.5233
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.358
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)5.275
Retinoic acid receptor RXR-gammaHomo sapiens (human)0.35
Nuclear receptor ROR-gammaHomo sapiens (human)0.1995
10 kDa heat shock protein, mitochondrialHomo sapiens (human)5.3
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1Homo sapiens (human)0.82
60 kDa chaperonin Escherichia coli6.7
10 kDa chaperonin Escherichia coli6.7
Nuclear receptor ROR-betaHomo sapiens (human)0.1259

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's0 (0.00)18.2507
2000's2 (18.18)29.6817
2010's5 (45.45)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Habs, M; Schmähl, D1
Adem, A; Mattsson, ME; Nordberg, A; Påhlman, S1
Boutwell, RK; Conrad, EA; Kishore, GS; Perchellet, JP1
Borroni, B; Cattabeni, F; Colciaghi, F; Di Luca, M; Gardoni, F; Marcello, E; Padovani, A; Zimmermann, M1
Kataoka, H; Madhyastha, H; Madhyastha, R; Maruyama, M; Nakajima, Y; Nurrahmah, QI; Purbasari, B; Watanabe, N1

Reviews

1 review(s) available for atropine and tretinoin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

10 other study(ies) available for atropine and tretinoin

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Life-span investigations for carcinogenicity of some immune-stimulating, immunodepressive and neurotropic substances in Sprague-Dawley-rats.
    Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology, 1976, May-03, Volume: 86, Issue:1

    Topics: Animals; Antilymphocyte Serum; Atropine; BCG Vaccine; Carcinogens; Female; Freund's Adjuvant; Ganglionic Stimulants; Immunosuppressive Agents; Male; Neoplasms, Experimental; Phenobarbital; Rats; Serum Albumin; Tretinoin

1976
Muscarinic receptors in human SH-SY5Y neuroblastoma cell line: regulation by phorbol ester and retinoic acid-induced differentiation.
    Brain research, 1987, Volume: 430, Issue:2

    Topics: Acetylcholinesterase; Atropine; Binding, Competitive; Cell Differentiation; Cell Line; Choline O-Acetyltransferase; Humans; Neuroblastoma; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Tetradecanoylphorbol Acetate; Tretinoin

1987
Effects of cell surface receptor-altering agents on the binding and biological activity of 12-O-tetradecanoylphorbol-13-acetate in isolated epidermal cells.
    Carcinogenesis, 1982, Volume: 3, Issue:10

    Topics: alpha-L-Fucosidase; Animals; Atropine; Binding Sites; Binding, Competitive; Carboxy-Lyases; Cell Membrane; Cholera Toxin; G(M1) Ganglioside; Galactose Oxidase; Kinetics; Mice; Neuraminidase; Ornithine Decarboxylase; Phentolamine; Phorbols; Phospholipases; Propranolol; Skin; Tetradecanoylphorbol Acetate; Tretinoin

1982
Acetylcholinesterase inhibitors increase ADAM10 activity by promoting its trafficking in neuroblastoma cell lines.
    Journal of neurochemistry, 2004, Volume: 90, Issue:6

    Topics: Acetylcholinesterase; ADAM Proteins; ADAM10 Protein; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Atropine; Blotting, Western; Brefeldin A; Bungarotoxins; Carbachol; Cell Differentiation; Cell Fractionation; Cell Line, Tumor; Cholinergic Agonists; Cholinesterase Inhibitors; Donepezil; Drug Interactions; Embryo, Mammalian; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Humans; Indans; Membrane Proteins; Metalloendopeptidases; Microscopy, Confocal; Muscarinic Antagonists; Neuroblastoma; Physostigmine; Piperidines; Protein Synthesis Inhibitors; Protein Transport; Tretinoin

2004
Retinoic acid attenuates nuclear factor kappaB mediated induction of NLRP3 inflammasome.
    Pharmacological reports : PR, 2022, Volume: 74, Issue:1

    Topics: Acetylcholine; Animals; Atropine; Carbachol; Cholinergic Agonists; Humans; Inflammasomes; Macrophages; Mice; Muscarinic Antagonists; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Receptors, Muscarinic; Signal Transduction; Tretinoin

2022