Compounds > atropine
Page last updated: 2024-09-05

atropine and topiramate

atropine has been researched along with topiramate in 8 studies

Compound Research Comparison

Studies
(atropine)		Trials
(atropine)		Recent Studies (post-2010)
(atropine)		Studies
(topiramate)		Trials
(topiramate)		Recent Studies (post-2010) (topiramate)
26,7111,2591,6973,1975571,329

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)topiramate (IC50)
Carbonic anhydrase 1Homo sapiens (human)0.25
Carbonic anhydrase 2Homo sapiens (human)0.8683
Carbonic anhydrase 2Rattus norvegicus (Norway rat)1.4
Carbonic anhydrase 4Bos taurus (cattle)0.054

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's6 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Baldwin, RA; Kubova, H; Sankar, R; Suchomelova, L; Thompson, KW; Wasterlain, CG1
Avoli, M; Biagini, G; Curia, G; D'Antuono, M; Kawasaki, H; Palmieri, C1
Allahverdiyev, O; Büget, B; Enginar, N; Türkmen, AZ1
Agarwal, N; Mazumdar, S; Sarma, B; Tripathy, K1

Reviews

1 review(s) available for atropine and topiramate

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

7 other study(ies) available for atropine and topiramate

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Treatment of experimental status epilepticus in immature rats: dissociation between anticonvulsant and antiepileptogenic effects.
    Pediatric research, 2006, Volume: 59, Issue:2

    Topics: Animals; Anticonvulsants; Atropine; Diazepam; Dose-Response Relationship, Drug; Electroencephalography; Fructose; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus; Topiramate

2006
Antiepileptic drugs and muscarinic receptor-dependent excitation in the rat subiculum.
    Neuropharmacology, 2007, Volume: 52, Issue:5

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Anticonvulsants; Atropine; Carbachol; Excitatory Amino Acid Antagonists; Fructose; GABA-A Receptor Antagonists; Hippocampus; Lamotrigine; Male; Membrane Potentials; Muscarinic Antagonists; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, Metabotropic Glutamate; Receptors, Muscarinic; Topiramate; Triazines

2007
Antimuscarinic-induced convulsions in fasted animals after food intake: evaluation of the effects of levetiracetam, topiramate and different doses of atropine.
    Naunyn-Schmiedeberg's archives of pharmacology, 2016, Volume: 389, Issue:1

    Topics: Animals; Anticonvulsants; Atropine; Eating; Fasting; Fructose; Levetiracetam; Male; Mice, Inbred BALB C; Muscarinic Antagonists; Piracetam; Seizures; Topiramate

2016
Acquired myopia followed by acquired hyperopia due to serous neurosensory retinal detachment following topiramate intake.
    European journal of ophthalmology, 2019, Volume: 29, Issue:1

    Topics: Adult; Atropine; Central Serous Chorioretinopathy; Fluorescein Angiography; Glaucoma, Angle-Closure; Humans; Hyperopia; Hypoglycemic Agents; Intraocular Pressure; Laser Therapy; Lasers, Solid-State; Male; Microscopy, Acoustic; Mydriatics; Myopia; Retinal Detachment; Tomography, Optical Coherence; Tonometry, Ocular; Topiramate; Visual Acuity

2019