Page last updated: 2024-09-05

atropine and thyroxine

atropine has been researched along with thyroxine in 34 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(thyroxine)
Trials
(thyroxine)
Recent Studies (post-2010) (thyroxine)
26,7111,2591,69738,9891,4106,550

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)thyroxine (IC50)
TransthyretinHomo sapiens (human)2.1939
UDP-glucuronosyltransferase 1A1 Homo sapiens (human)5.25
Solute carrier organic anion transporter family member 4C1Homo sapiens (human)8
Bile acid receptorHomo sapiens (human)7.86

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199021 (61.76)18.7374
1990's8 (23.53)18.2507
2000's2 (5.88)29.6817
2010's3 (8.82)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Melander, A; Sundler, F1
Kiyono, S; Koike, T; Nishimura, C1
Connors, JM; Hedge, GA; Huffman, LJ; Michalkiewicz, M; Pietrzyk, Z1
Frolkis, VV; Gorban, EN; Moroz, EV1
Adir, J; Miller, RL; Verma, PS1
Maayan, ML; Sellitto, RV; Volpert, EM1
Hadden, DR; McDevitt, DG; Montgomery, DA; Shanks, RG; Weaver, JA1
Arnsdorf, MF; Childers, RW1
Bucher, K; Floersheim, GL1
Côté, P; Harrison, DC; Polumbo, RA1
Freedberg, AS; Johnson, PN; Marshall, JM1
Dunnigan, MG; Fyfe, T; Harland, WA; Orr, JS1
Adolph, EF1
Levy, L1
Schrogie, JJ; Solomon, HM1
Cairoli, VJ; Crout, JR1
Petkov, O1
Meier, AH; Ottenweller, JE1
From, A; Maayan, ML; Volpert, EM1
Ishac, EJ; Pennefather, JN1
Naim, KL; Rabindranauth, P; Scholz, PM; Tse, J; Weiss, HR1
Elghozi, JL; Laude, D; Ponchon, P; Safa-Tisseront, V2
Bandyopadhyay, S; Ghosh, C; Medda, JN1
Ghosh, C; Medda, JN1
Arad, M; Balas, N; Rabinowitz, B; Shainberg, A1
DIMASCOLO, R; MASINI, V1
BRAY, GA1
ALGER, EA; BOCCABELLA, AV; VINGER, PF1
Chatterji, U; Chaudhuri-Sengupta, S; Dasgupta, R; Maiti, BR; Nag, D; Nag, TC1

Reviews

2 review(s) available for atropine and thyroxine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[THERAPY OF THE MORGAGNI-ADAMS-STOKES SYNDROME].
    Recenti progressi in medicina, 1964, Volume: 36

    Topics: Adams-Stokes Syndrome; Adrenal Cortex Hormones; Amphetamine; Amphetamines; Amyl Nitrite; Atropine; Barium; Caffeine; Chlorothiazide; Digitalis Glycosides; Electrocardiography; Ephedrine; Epinephrine; Geriatrics; Heart Block; Heart Massage; Humans; Isoproterenol; Lactates; Magnesium Sulfate; Methamphetamine; Procainamide; Purines; Quinidine; Thyroxine

1964

Trials

1 trial(s) available for atropine and thyroxine

ArticleYear
The role of the thyroid in the control of heart-rate.
    Lancet (London, England), 1968, May-11, Volume: 1, Issue:7550

    Topics: Adult; Age Factors; Aged; Atropine; Female; Heart Rate; Humans; Hyperthyroidism; Hypothyroidism; Male; Middle Aged; Propranolol; Sympathetic Nervous System; Tachycardia; Thyroid Gland; Thyroxine

1968

Other Studies

31 other study(ies) available for atropine and thyroxine

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Presence and influence of cholinergic nerves in the mouse thyroid.
    Endocrinology, 1979, Volume: 105, Issue:1

    Topics: Animals; Atropine; Carbachol; Cholinergic Fibers; Female; Iodine; Mice; Mice, Inbred Strains; Thyroid Gland; Thyroxine

1979
[The effects of premedication on thyroid hormone T3, T4 and R.S.U. in man (author's transl)].
    Masui. The Japanese journal of anesthesiology, 1978, Volume: 27, Issue:13

    Topics: Adolescent; Adult; Aged; Anesthetics; Atropine; Female; Humans; Male; Meperidine; Middle Aged; Pentobarbital; Premedication; Resins, Plant; Thyroid Diseases; Thyroid Function Tests; Thyroxine; Triiodothyronine

1978
Muscarinic modulation of the vasodilatory effects of vasoactive intestinal peptide at the rat thyroid gland.
    Neuroendocrinology, 1991, Volume: 53, Issue:1

    Topics: Acetylcholine; Animals; Atropine; Blood Flow Velocity; Male; Methacholine Chloride; Muscarinic Antagonists; Nicotine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine; Vasoactive Intestinal Peptide; Vasodilation

1991
Peculiarities of neural regulation of the thyroid, adrenocortical and testicular functions in old age.
    Mechanisms of ageing and development, 1990, Volume: 51, Issue:1

    Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Aging; Animals; Atropine; Dibenzylchlorethamine; Ketosteroids; Male; Propranolol; Rats; Rats, Inbred Strains; Reserpine; Testis; Testosterone; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine

1990
Effect of experimental hyperthyroidism on atropine pharmacokinetics in sheep.
    Methods and findings in experimental and clinical pharmacology, 1990, Volume: 12, Issue:2

    Topics: Animals; Atropine; Hyperthyroidism; Injections, Intramuscular; Sheep; Thyroxine

1990
Dopamine and L-dopa: inhibition of thyrotropin-stimulated thyroidal thyroxine release.
    Endocrinology, 1986, Volume: 118, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Apomorphine; Aromatic Amino Acid Decarboxylase Inhibitors; Atropine; Bucladesine; Carbidopa; Cyclic AMP; Dopamine; Dopamine beta-Hydroxylase; Female; Levodopa; Mice; Receptors, Adrenergic, alpha; Receptors, Dopamine; Sulpiride; Thyroid Gland; Thyrotropin; Thyroxine

1986
Atrial electrophysiology in experimental hyperthyroidism in rabbits.
    Circulation research, 1970, Volume: 26, Issue:5

    Topics: Animals; Atrial Fibrillation; Atropine; Electrophysiology; Heart Atria; Hyperthyroidism; Perfusion; Rabbits; Tachycardia; Thyroid Function Tests; Thyroxine; Time Factors

1970
Effects of thyroxine, oxyphenbutazone and imipramine on an inflammatory graft-versus-host reaction in chicks.
    Agents and actions, 1972, Volume: 2, Issue:4

    Topics: Animals; Atropine; Chickens; Gold; Graft vs Host Reaction; Hydralazine; Imipramine; Inflammation; Lymphocyte Transfusion; Male; Methysergide; Oxyphenbutazone; Peptides; Thyroxine; Transplantation, Homologous

1972
Thyronamine, a new inotropic agent: its cardiovascular effects and mechanism of action.
    Cardiovascular research, 1974, Volume: 8, Issue:6

    Topics: Animals; Atropine; Blood Pressure; Cardiac Output; Cardiovascular System; Catecholamines; Catheterization; Dogs; Heart Rate; Heart Ventricles; Hemodynamics; Isoproterenol; Myocardial Contraction; Norepinephrine; Pacemaker, Artificial; Phenethylamines; Phenoxybenzamine; Phenyl Ethers; Propranolol; Reserpine; Sympathomimetics; Thyroxine; Vascular Resistance

1974
Action of thyroid hormone on the transmembrane potentials from sinoatrial node cells and atrial muscle cells in isolated atria of rabbits.
    Cardiology, 1973, Volume: 58, Issue:5

    Topics: Action Potentials; Animals; Atropine; Cell Membrane; Electric Stimulation; Heart Atria; Hypothyroidism; Membrane Potentials; Propranolol; Sinoatrial Node; Thyroid Hormones; Thyroxine

1973
Cardiac effects of cold-induced hyperthyroidism and the seasonal variation in incidence of myocardial infarction.
    British journal of experimental pathology, 1971, Volume: 52, Issue:2

    Topics: Animals; Atropine; Cold Temperature; Heart; Heart Rate; Hyperthyroidism; Male; Myocardial Infarction; Myocardium; Organ Size; Propranolol; Rats; Seasons; Thyroxine

1971
Ranges of heart rates and their regulations at various ages (rat).
    The American journal of physiology, 1967, Volume: 212, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Atropine; Electric Stimulation; Electrocardiography; Electroshock; Fetal Heart; Heart; Heart Conduction System; Heart Rate; Parasympathetic Nervous System; Rats; Sympathetic Nervous System; Sympatholytics; Sympathomimetics; Thyroxine

1967
Some effects of thyroxin on immunologic anaphylaxis.
    Life sciences, 1967, Aug-01, Volume: 6, Issue:15

    Topics: Anaphylaxis; Animals; Atropine; Dibenzylchlorethamine; Diphenhydramine; Guinea Pigs; Iproniazid; Lysergic Acid Diethylamide; Male; Mice; Passive Cutaneous Anaphylaxis; Thyroxine

1967
The effect of various drugs on the binding of warfarin-14C to human albumin.
    Biochemical pharmacology, 1967, Jul-07, Volume: 16, Issue:7

    Topics: Atropine; Butyrates; Carbon Isotopes; Phenethylamines; Phenylbutazone; Protein Binding; Serum Albumin; Sulfaphenazole; Thyroxine; Warfarin

1967
Role of the autonomic nervous system in the resting tachycardia of experimental hyperthyroidism.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 158, Issue:1

    Topics: Animals; Atropine; Autonomic Nervous System; Catecholamines; Chlorisondamine; Electric Stimulation; Heart Conduction System; Heart Rate; Hyperthyroidism; Male; Norepinephrine; Oxygen Consumption; Propranolol; Rats; Reserpine; Sinoatrial Node; Tachycardia; Thyroxine; Vagus Nerve

1967
Some functional changes in experimentally induced cardiac overload.
    Acta physiologica et pharmacologica Bulgarica, 1983, Volume: 9, Issue:3

    Topics: Aminooxyacetic Acid; Animals; Atropine; Cardiomegaly; Disease Models, Animal; Drug Combinations; Electrocardiography; Heart; Isoproterenol; Male; Oxprenolol; Phentolamine; Rabbits; Rats; Rats, Inbred Strains; Thyroxine; Triiodothyronine

1983
Adrenal innervation may be an extrapituitary mechanism able to regulate adrenocortical rhythmicity in rats.
    Endocrinology, 1982, Volume: 111, Issue:4

    Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Atropine; Circadian Rhythm; Hypophysectomy; Male; Pentobarbital; Rats; Spinal Cord; Thyroxine

1982
Acetylcholine and norepinephrine: compared actions thyroid metabolism.
    Endocrinology, 1983, Volume: 112, Issue:4

    Topics: Acetylcholine; Animals; Atropine; Bucladesine; Cyclic AMP; Cyclic GMP; Female; Humans; Iodides; Mice; Norepinephrine; Thyroid Gland; Thyrotropin; Thyroxine

1983
The effects of altered thyroid state upon responses mediated by atrial muscarinic receptors in the rat.
    British journal of pharmacology, 1983, Volume: 79, Issue:2

    Topics: Animals; Atropine; Carbachol; Heart; Heart Rate; In Vitro Techniques; Male; Methacholine Compounds; Methimazole; Myocardial Contraction; Rats; Receptors, Muscarinic; Thyroid Diseases; Thyroxine

1983
Basal muscarinic activity does not impede beta-adrenergic activation in rabbit hearts in controls or thyroxine-induced cardiac hypertrophy.
    Journal of cardiovascular pharmacology, 1997, Volume: 30, Issue:4

    Topics: Adrenergic beta-Agonists; Animals; Atropine; Body Weight; Cardiomegaly; Cyclic AMP; Cyclic GMP; Isoproterenol; Muscarinic Antagonists; Myocardium; Organ Size; Rabbits; Receptors, Adrenergic, beta; Receptors, Muscarinic; Thyroxine

1997
Contribution of the autonomic nervous system to blood pressure and heart rate variability changes in early experimental hyperthyroidism.
    European journal of pharmacology, 1998, Jul-10, Volume: 352, Issue:2-3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atenolol; Atropine; Autonomic Nervous System; Blood Pressure; Heart Rate; Hyperthyroidism; Male; Prazosin; Rats; Rats, Wistar; Stress, Physiological; Thyroxine

1998
Protective role of thyroxine in methylparathion intoxicated chick embryos.
    Drug and chemical toxicology, 1998, Volume: 21, Issue:4

    Topics: Animals; Atropine; Body Constitution; Body Weight; Chick Embryo; Cholinesterase Inhibitors; Cholinesterases; Drug Antagonism; Methyl Parathion; Mortality; Thyroxine

1998
Autonomic contribution to the blood pressure and heart rate variability changes in early experimental hyperthyroidism.
    Journal of hypertension, 1998, Volume: 16, Issue:12 Pt 2

    Topics: Animals; Atenolol; Atropine; Autonomic Nervous System; Blood Pressure; Cardiomegaly; Disease Models, Animal; Heart Rate; Hyperthyroidism; Male; Prazosin; Rats; Rats, Wistar; Tachycardia; Thyroid Hormones; Thyroxine; Vagus Nerve

1998
Ameliorating effects of thyroxine and atropine in phosphamidon intoxicated chick embryos.
    Biomedical and environmental sciences : BES, 1999, Volume: 12, Issue:1

    Topics: Animals; Atropine; Body Weight; Central Nervous System; Chick Embryo; Cholinesterase Inhibitors; Cholinesterases; Dose-Response Relationship, Drug; Insecticides; Kidney; Liver; Phosphamidon; Thyroxine

1999
Modulation of cardiac A1-adenosine receptors in rats following treatment with agents affecting heart rate.
    Molecular and cellular biochemistry, 2002, Volume: 231, Issue:1-2

    Topics: Adenosine; Animals; Atropine; Down-Regulation; Heart Rate; Isoproterenol; Male; Myocardium; Rats; Rats, Wistar; Receptors, Purinergic P1; Swimming; Thyroxine; Up-Regulation

2002
STUDIES ON THE INTERACTIONS OF THYROID HORMONE AND CATECHOLAMINES.
    The Journal of clinical investigation, 1964, Volume: 43

    Topics: Adrenal Medulla; Atropine; Basal Metabolism; Catecholamines; Epinephrine; Guanethidine; Heart Function Tests; Manometry; Pharmacology; Rats; Research; Reserpine; Thyroid Hormones; Thyroidectomy; Thyroxine; Triiodothyronine

1964
IN VITRO RESPONSE OF INTESTINAL SEGMENTS OF MICE WITH HEREDITARY MUSCULAR DYSTROPHY TO VARIOUS PHARMACOLOGIC AGENTS.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1964, Volume: 116

    Topics: Acetylcholine; Atropine; Barium; Colon; Duodenum; Genetics; Guanethidine; Hexamethonium Compounds; Ileum; In Vitro Techniques; Intestines; Jejunum; Mice; Muscular Dystrophies; Norepinephrine; Pharmacology; Research; Thyroxine

1964
Ultrastructural and hormonal modulations of the thyroid gland following arecoline treatment in albino mice.
    Molecular and cellular endocrinology, 2010, May-05, Volume: 319, Issue:1-2

    Topics: Analysis of Variance; Animals; Arecoline; Atropine; Cell Size; Cholinergic Agonists; Cholinergic Antagonists; Epithelial Cells; Male; Mice; Microscopy, Electron, Transmission; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine

2010