Page last updated: 2024-09-05

atropine and thiourea

atropine has been researched along with thiourea in 39 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(thiourea)
Trials
(thiourea)
Recent Studies (post-2010) (thiourea)
26,7111,2591,6976,959461,737

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)thiourea (IC50)
UreaseCanavalia ensiformis (jack bean)0.56
Serine-protein kinase ATMHomo sapiens (human)0.2
Serine/threonine-protein kinase ATRHomo sapiens (human)0.2

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199030 (76.92)18.7374
1990's5 (12.82)18.2507
2000's3 (7.69)29.6817
2010's1 (2.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Berglindh, T1
Wan, BY1
Albinus, M; Blair, EL; Reed, JD; Thompson, MH; Venables, CW1
Haines, V; Karpinski, E; Schachter, M1
Bunce, KT; Matheson, FR; Parsons, ME1
Angus, JA; Black, JW2
Szelenyi, I; Thiemer, K1
McIsaac, RL; Wilson, GW1
Andersson, H; Uvnäs-Wallensten, K1
Kwong, F; Orzechowski, RF1
Thjodleifsson, B; Wormsley, KG2
Bast, A; Brozius, MM; Leurs, R; Smit, MJ; Timmerman, H1
Chediak, AD; Csete, ME; Elsasser, S; Gazeroglu, H; Wanner, A1
Dolata, J; Lindberg, S; Mercke, U1
Almeida, L; Figueiredo, A; Gonçalo, M; Poiares-Baptista, A; Ribeiro, CA; Teixeira, F1
Bertaccini, G; Coruzzi, G1
Foreman, JC; Rising, TJ; Webber, SE1
Del Soldato, P2
Fuenmayor, L; Lentino, A1
Ambache, N; Killick, SW; Zar, MA1
Grossman, MI; Konturek, SJ1
Konturek, SJ; Obtulowicz, W; Rehfeld, JF; Tasler, J1
Bank, S; Barbezat, GO; Daniel, M; Terblanche, J; Waterworth, MW1
carroll, PR; Glover, WE; Latt, N1
Demitrescu, T; Konturek, SJ; Radecki, T1
Chemnitius, KH; Lemke, H; Oettel, M1
Hartmann, E1
Engler, H; Szelenyi, I1
Maeno, H; Takagi, T; Takeda, M1
Bugajski, J; Gadek, A1
Beck, H; Engler, H; Szelenyi, I1
Hemedah, M; Mitchelson, F1
Murakami, Y; Nakamura, K; Okada, S; Wang, M; Yokotani, K1
Chiba, S; Furukawa, Y; Hirose, M; Kurogouchi, F; Nakajima, K; Tsuboi, M; Zhao, D1
Aizawa, H; Fukuyama, S; Hara, N; Inoue, H; Koto, H; Matsumoto, K1
Abramochkin, DV; Tapilina, SV; Vornanen, M1

Trials

1 trial(s) available for atropine and thiourea

ArticleYear
Gastric response to metiamide.
    British medical journal, 1974, May-11, Volume: 2, Issue:5914

    Topics: Atropine; Depression, Chemical; Duodenal Ulcer; Duodenum; Gastric Juice; Humans; Infusions, Parenteral; Injections, Subcutaneous; Pentagastrin; Pepsin A; Perfusion; Secretory Rate; Stomach Ulcer; Thiourea

1974

Other Studies

38 other study(ies) available for atropine and thiourea

ArticleYear
Effects of common inhibitors of gastric acid secretion on secretagogue-induced respiration and aminopyrine accumulation in isolated gastric glands.
    Biochimica et biophysica acta, 1977, Jan-04, Volume: 464, Issue:1

    Topics: Aminopyrine; Animals; Atropine; Biological Transport; Bucladesine; Burimamide; Gastric Juice; Gastric Mucosa; Histamine; In Vitro Techniques; Kinetics; Oxygen Consumption; Rabbits; Thiocyanates; Thiourea

1977
Metiamide and stimulated acid secretion from the isolated non-distended and distended mouse stomach.
    The Journal of physiology, 1977, Volume: 266, Issue:2

    Topics: Animals; Atropine; Bucladesine; Dose-Response Relationship, Drug; Female; Gastric Juice; Gastric Mucosa; In Vitro Techniques; Male; Metiamide; Mice; Pentagastrin; Phosphodiesterase Inhibitors; Secretory Rate; Stimulation, Chemical; Thiourea

1977
Proceedings: The interaction of cholinergic and histaminic blockades on the partieta cell: therapeutic possibilities.
    The British journal of surgery, 1975, Volume: 62, Issue:2

    Topics: Animals; Atropine; Cats; Drug Therapy, Combination; Histamine H1 Antagonists; Imidazoles; Peptic Ulcer; Stomach; Sulfides; Thiourea

1975
Gastric secretion during anaesthesia and its inhibition by metiamide and other drugs.
    Experientia, 1975, Aug-15, Volume: 31, Issue:8

    Topics: Animals; Atropine; Chloralose; Dogs; Gastric Juice; Gastric Mucosa; Hexamethonium Compounds; Histamine H1 Antagonists; Metiamide; Thiourea; Urethane; Vagus Nerve

1975
Inhibition of pepsin secretion by metiamide and atropine in the conscious rat.
    Agents and actions, 1979, Volume: 9, Issue:2

    Topics: Animals; Atropine; Denervation; Female; Fistula; Metiamide; Pepsin A; Rats; Stomach; Thiourea

1979
Low estimation of pA2 values for metiamide and atropine for acid secretion in the isolated mouse stomach [proceedings].
    Agents and actions, 1979, Volume: 9, Issue:1

    Topics: Animals; Atropine; Dose-Response Relationship, Drug; Gastric Mucosa; In Vitro Techniques; Metiamide; Mice; Muscle Contraction; Muscle, Smooth; Thiourea

1979
Analysis of anomalous pKb values for metiamide and atropine in the isolated stomach of the mouse.
    British journal of pharmacology, 1979, Volume: 67, Issue:1

    Topics: Animals; Atropine; Bethanechol Compounds; Dose-Response Relationship, Drug; Gastric Juice; Metiamide; Mice; Muscle Contraction; Muscle, Smooth; Stomach; Thiourea

1979
Influence of metiamide and atropine on pepsinogen secretion in the conscious rat.
    Experientia, 1977, Dec-15, Volume: 33, Issue:12

    Topics: Animals; Atropine; Carbachol; Gastric Acidity Determination; Gastric Fistula; Histamine; Male; Metiamide; Pentagastrin; Pepsinogens; Rats; Thiourea

1977
Modification of gastric acid secretion and mucosal blood flow in the conscious rat by atropine and metiamide [proceedings].
    The Journal of physiology, 1977, Volume: 265, Issue:1

    Topics: Animals; Atropine; Female; Gastric Mucosa; Metiamide; Rats; Thiourea

1977
Effect of atropine and methiamide on vagally induced gastric acid secretion and gastrin release in anesthetized cats.
    Acta physiologica Scandinavica, 1977, Volume: 99, Issue:4

    Topics: Anesthesia, General; Animals; Atropine; Cats; Electric Stimulation; Gastric Juice; Gastric Mucosa; Gastrins; Metiamide; Secretory Rate; Thiourea; Time Factors; Vagus Nerve

1977
Resistance to blockade of vasodepressor responses to tolazoline by chlorpheniramine and metiamide in rabbit hindlimb vasculature.
    Research communications in chemical pathology and pharmacology, 1977, Volume: 16, Issue:4

    Topics: Acetylcholine; Animals; Atropine; Blood Pressure; Chlorpheniramine; Drug Interactions; Hindlimb; Histamine; Isoproterenol; Metiamide; Propranolol; Rabbits; Regional Blood Flow; Thiourea; Tolazoline; Vasomotor System

1977
Aspects of the effect of metiamide on pentagastrin-stimulated and basal gastric secretion of acid and pepsin in man.
    Gut, 1975, Volume: 16, Issue:7

    Topics: Atropine; Dose-Response Relationship, Drug; Drug Synergism; Duodenal Ulcer; Gastric Juice; Humans; Metiamide; Pentagastrin; Pepsin A; Secretory Rate; Stomach; Stomach Ulcer; Thiourea

1975
Effects of histamine H1-, H2- and H3-receptor selective drugs on the mechanical activity of guinea-pig small and large intestine.
    British journal of pharmacology, 1991, Volume: 102, Issue:1

    Topics: Animals; Atropine; Dimaprit; Electric Stimulation; Guanidines; Guinea Pigs; Histamine; In Vitro Techniques; Intestine, Large; Intestine, Small; Male; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Pinacidil; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Stereoisomerism; Tetraethylammonium Compounds; Thiourea

1991
Effect of histamine on tracheal mucosal perfusion, water content and airway smooth muscle in sheep.
    Respiration physiology, 1991, Volume: 84, Issue:2

    Topics: Animals; Atropine; Chlorpheniramine; Dimaprit; Female; Histamine; Lung Volume Measurements; Metiamide; Mucous Membrane; Muscle, Smooth; Receptors, Cholinergic; Receptors, Histamine H1; Receptors, Histamine H2; Regional Blood Flow; Sheep; Thiourea; Trachea; Water

1991
Histamine stimulation of mucociliary activity in the rabbit maxillary sinus.
    The Annals of otology, rhinology, and laryngology, 1990, Volume: 99, Issue:8

    Topics: Animals; Atropine; Cilia; Cimetidine; Dimaprit; Female; Histamine; Histamine H2 Antagonists; Male; Maxillary Sinus; Mucociliary Clearance; Pyrilamine; Rabbits; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Muscarinic; Thiourea

1990
Mechanism of action of doxepin in the treatment of chronic urticaria.
    Fundamental & clinical pharmacology, 1990, Volume: 4, Issue:2

    Topics: Adult; Aged; Animals; Atropine; Carbachol; Chronic Disease; Dimaprit; Doxepin; Female; Gastric Juice; Guinea Pigs; Heart; Histamine; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Pylorus; Pyrilamine; Rats; Thiourea; Urticaria

1990
Histamine H2-receptor agonists and antagonists on pancreatic exocrine secretion of the dog.
    Agents and actions, 1985, Volume: 16, Issue:3-4

    Topics: Animals; Atropine; Ceruletide; Dimaprit; Dogs; Dose-Response Relationship, Drug; Female; Histamine H2 Antagonists; Imidazoles; Impromidine; Male; Pancreas; Receptors, Histamine; Receptors, Histamine H2; Thiourea

1985
A study of the histamine H2-receptor mediating relaxation of the parenchymal lung strip preparation of the guinea-pig.
    British journal of pharmacology, 1985, Volume: 86, Issue:2

    Topics: Animals; Atropine; Colforsin; Dimaprit; Female; Guinea Pigs; In Vitro Techniques; Lung; Male; Muscle Relaxation; Muscle, Smooth; Propranolol; Pyridines; Receptors, Histamine; Receptors, Histamine H2; Thiourea

1985
Gastric lesion-preventing or -potentiating activity of clonidine in rats.
    Japanese journal of pharmacology, 1986, Volume: 41, Issue:2

    Topics: Animals; Anti-Ulcer Agents; Atropine; Clonidine; Dimaprit; Female; Ranitidine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Stomach Ulcer; Thiourea

1986
Effect of 10 undecen 1-YL thiopseudourea iodide (AHR-1911) on rat arterial pressure and capillary permeability.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1973, Volume: 143, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Atropine; Blood Pressure; Capillary Permeability; Chlorpheniramine; Diphenhydramine; Dose-Response Relationship, Drug; Hexamethonium Compounds; Histamine H1 Antagonists; Male; Onium Compounds; Polymyxins; Promethazine; Propranolol; Rats; Thiourea; Undecylenic Acids

1973
Antagonism by burimamide of inhibitions induced by histamine in plexus-containing longitudinal muscle preparations from guinea-pig ileum.
    British journal of pharmacology, 1973, Volume: 48, Issue:2

    Topics: Animals; Atropine; Benzyl Compounds; Dose-Response Relationship, Drug; Electric Stimulation; Ethylenediamines; Guinea Pigs; Histamine; Histamine H1 Antagonists; Ileum; Imidazoles; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Pyridines; Receptors, Drug; Thiourea

1973
Inhibition of acid secretion in dog by metiamide, a histamine antagonist acting on H2 receptors.
    Gastroenterology, 1974, Volume: 66, Issue:4

    Topics: Animals; Atropine; Depression, Chemical; Dogs; Gastric Fistula; Gastric Juice; Glucose; Histamine; Histamine H1 Antagonists; Imidazoles; Liver Extracts; Pentagastrin; Receptors, Drug; Sulfides; Thiourea

1974
Effect of metiamide, a histamine H2-receptor antagonist, on mucosal blood flow and serum gastrin level.
    Gastroenterology, 1974, Volume: 66, Issue:5

    Topics: Aminopyrine; Animals; Atropine; Bethanechol Compounds; Blood Flow Velocity; Dogs; Food; Gastric Acidity Determination; Gastric Juice; Gastric Mucosa; Gastrins; Histamine H1 Antagonists; Imidazoles; Pentagastrin; Sulfides; Thiourea

1974
Effect of burimamide on histamine- and pentagastrin-stimulated acid and pepsin secretion in the pig.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1974, Sep-28, Volume: 48, Issue:47

    Topics: Animals; Atropine; Denervation; Depression, Chemical; Gastric Fistula; Gastric Juice; Histamine H1 Antagonists; Imidazoles; Pentagastrin; Pepsin A; Secretory Rate; Stomach; Swine; Thiourea

1974
Cardiovascular histamine receptors in the rabbit.
    The Australian journal of experimental biology and medical science, 1974, Volume: 52, Issue:Pt 3

    Topics: Animals; Atropine; Benzyl Compounds; Blood Pressure; Chemoreceptor Cells; Depression, Chemical; Dose-Response Relationship, Drug; Drug Synergism; Ethylenediamines; Female; Heart Rate; Histamine; Histamine H1 Antagonists; Imidazoles; Injections, Intravenous; Male; Pyridines; Rabbits; Stimulation, Chemical; Thiourea; Vagotomy; Vagus Nerve

1974
The role of histamine receptors in the stimulation of gastric acid secretion.
    The American journal of digestive diseases, 1974, Volume: 19, Issue:11

    Topics: Animals; Atropine; Bethanechol Compounds; Cats; Ceruletide; Gastrectomy; Gastric Juice; Gastric Mucosa; Histamine; Histamine H1 Antagonists; Imidazoles; Insulin; Pentagastrin; Peptones; Receptors, Drug; Sulfides; Thiourea

1974
[Pharmacologic-endocrinological findings in animal experiments with TURISYNCHRON and SUISYNCHROM. 2. Toxicologic findings].
    Archiv fur experimentelle Veterinarmedizin, 1974, Volume: 28, Issue:5

    Topics: Acute Disease; Administration, Oral; Animals; Atropine; Body Weight; Chlorpromazine; Chronic Disease; Duodenal Diseases; Female; Injections, Subcutaneous; Lethal Dose 50; Maternal-Fetal Exchange; Methallibure; Mice; Organ Size; Papaverine; Peptic Ulcer; Poisoning; Pregnancy; Rats; Sex Factors; Structure-Activity Relationship; Thiourea; Zinc

1974
[Treatment of urinary tract infections in gynecology with Sulfa-Dysural].
    Munchener medizinische Wochenschrift (1950), 1969, Nov-07, Volume: 111, Issue:45

    Topics: Analgesics; Atropine; Barbiturates; Cystitis; Ephedrine; Female; Humans; Orotic Acid; Parasympatholytics; Pelvic Inflammatory Disease; Pyelitis; Sulfonamides; Thiourea; Urinary Bladder Fistula; Urinary Tract Infections

1969
The effect of atropine and metiamide on pepsin secretion of the rat.
    Agents and actions, 1980, Volume: 10, Issue:5

    Topics: Animals; Atropine; Gastric Mucosa; Histamine H2 Antagonists; Hydrochloric Acid; Male; Metiamide; Pepsin A; Perfusion; Rats; Sodium Chloride; Thiourea

1980
Kinetics of antisecretory action of a new H2-antagonist, YM-11170, in conscious dogs.
    European journal of pharmacology, 1983, Aug-05, Volume: 91, Issue:4

    Topics: Animals; Atropine; Cimetidine; Dimaprit; Dogs; Famotidine; Gastric Acid; Gastric Mucosa; Histamine H2 Antagonists; Kinetics; Male; Methacholine Chloride; Methacholine Compounds; Pentagastrin; Thiazoles; Thiourea

1983
Effect of intracerebroventricular impromidine on pituitary-adrenocortical response to stress in rats.
    Agents and actions, 1984, Volume: 14, Issue:5-6

    Topics: Adrenal Cortex; Animals; Atropine; Cimetidine; Corticosterone; Dimaprit; Imidazoles; Impromidine; Injections, Intraventricular; Male; Methylhistamines; Pituitary Gland; Propranolol; Rats; Rats, Inbred Strains; Receptors, Histamine H2; Restraint, Physical; Stress, Physiological; Sympatholytics; Thiourea

1984
Studies with specific agonists and antagonists of the role of histamine H1- and H2-receptor activation in the pathogenesis of gastric lesions in rats.
    Agents and actions, 1984, Volume: 14, Issue:2

    Topics: Aminopyridines; Animals; Atropine; Dimaprit; Drug Interactions; Female; Histamine; Pyridines; Pyrilamine; Ranitidine; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Stomach Ulcer; Thiourea

1984
Influence of metiamide and atropine on acid and pepsin secretion in the anaesthetized Heidenhain cat.
    Agents and actions, 1981, Volume: 11, Issue:1-2

    Topics: Anesthesia; Animals; Atropine; Carbachol; Cats; Drug Interactions; Gastric Acid; Histamine; Male; Metiamide; Pentagastrin; Pepsin A; Salicylates; Thiourea

1981
Comparison of the effects of histamine and N(alpha)-methylhistamine on neuronal function in the guinea-pig oesophagus and ileum.
    The Journal of pharmacy and pharmacology, 1997, Volume: 49, Issue:12

    Topics: Acetylcholine; Animals; Atropine; Dose-Response Relationship, Drug; Electric Stimulation; Esophagus; Guinea Pigs; Histamine; Histamine Antagonists; Ileum; Imidazoles; In Vitro Techniques; Methylhistamines; Muscle, Skeletal; Muscle, Smooth; Neurons; Neurons, Afferent; Pyrilamine; Receptors, Cholinergic; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Substance P; Tetrodotoxin; Thiourea; Vagus Nerve

1997
Histamine H(3) receptor-mediated inhibition of endogenous acetylcholine release from the isolated, vascularly perfused rat stomach.
    European journal of pharmacology, 2000, Mar-24, Volume: 392, Issue:1-2

    Topics: Acetylcholine; Animals; Atropine; Gastric Mucosa; GTP-Binding Proteins; Histamine; Imidazoles; Male; Methylhistamines; Perfusion; Pertussis Toxin; Piperidines; Rats; Rats, Wistar; Receptors, Histamine H3; Thiourea; Vagus Nerve; Virulence Factors, Bordetella

2000
A Na+/Ca2+ exchanger inhibitor, KB-R7943, caused negative inotropic responses and negative followed by positive chronotropic responses in isolated, blood-perfused dog heart preparations.
    Japanese journal of pharmacology, 2000, Volume: 82, Issue:2

    Topics: Animals; Atropine; Depression, Chemical; Dogs; Dose-Response Relationship, Drug; Heart Rate; Hexamethonium; Imipramine; Isoproterenol; Myocardial Contraction; Ouabain; Perfusion; Propranolol; Sodium-Calcium Exchanger; Tetrodotoxin; Thiourea; Verapamil

2000
Effect of dimethylthiourea, a hydroxyl radical scavenger, on cigarette smoke-induced bronchoconstriction in guinea pigs.
    European journal of pharmacology, 2000, Sep-01, Volume: 403, Issue:1-2

    Topics: Acetylcholine; Animals; Atropine; Bronchoconstriction; Dose-Response Relationship, Drug; Electric Stimulation; Free Radical Scavengers; Guinea Pigs; Hydroxyl Radical; Insufflation; Lung; Neurokinin A; Pressure; Thiourea; Tobacco Smoke Pollution; Vagus Nerve; Vasodilator Agents

2000
A new potassium ion current induced by stimulation of M2 cholinoreceptors in fish atrial myocytes.
    The Journal of experimental biology, 2014, May-15, Volume: 217, Issue:Pt 10

    Topics: Animals; Atropine; Carbachol; Carps; Cholinergic Agonists; Fish Proteins; Heart Atria; Muscarinic Antagonists; Myocytes, Cardiac; Oncorhynchus mykiss; Patch-Clamp Techniques; Potassium; Potassium Channels, Inwardly Rectifying; Receptor, Muscarinic M2; Sodium-Calcium Exchanger; Thiourea

2014