Compounds > atropine
Page last updated: 2024-09-05

atropine and tetracycline

atropine has been researched along with tetracycline in 31 studies

Compound Research Comparison

Studies
(atropine)		Trials
(atropine)		Recent Studies (post-2010)
(atropine)		Studies
(tetracycline)		Trials
(tetracycline)		Recent Studies (post-2010) (tetracycline)
26,7111,2591,69721,5249773,656

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)tetracycline (IC50)
90-kda heat shock protein beta HSP90 beta, partialHomo sapiens (human)22.4474
heat shock protein HSP 90-alpha isoform 2Homo sapiens (human)22.4474
tyrosine-protein phosphatase non-receptor type 7 isoform 2Homo sapiens (human)8.33
30S ribosomal protein S6Escherichia coli K-124.58
30S ribosomal protein S7Escherichia coli K-124.58
50S ribosomal protein L15Escherichia coli K-124.58
50S ribosomal protein L10Escherichia coli K-124.58
50S ribosomal protein L11Escherichia coli K-124.58
50S ribosomal protein L7/L12Escherichia coli K-124.58
50S ribosomal protein L19Escherichia coli K-124.58
50S ribosomal protein L1Escherichia coli K-124.58
50S ribosomal protein L20Escherichia coli K-124.58
50S ribosomal protein L27Escherichia coli K-124.58
50S ribosomal protein L28Escherichia coli K-124.58
50S ribosomal protein L29Escherichia coli K-124.58
50S ribosomal protein L31Escherichia coli K-124.58
50S ribosomal protein L31 type BEscherichia coli K-124.58
50S ribosomal protein L32Escherichia coli K-124.58
50S ribosomal protein L33Escherichia coli K-124.58
50S ribosomal protein L34Escherichia coli K-124.58
50S ribosomal protein L35Escherichia coli K-124.58
50S ribosomal protein L36Escherichia coli K-124.58
30S ribosomal protein S10Escherichia coli K-124.58
30S ribosomal protein S11Escherichia coli K-124.58
30S ribosomal protein S12Escherichia coli K-124.58
30S ribosomal protein S13Escherichia coli K-124.58
30S ribosomal protein S16Escherichia coli K-124.58
30S ribosomal protein S18Escherichia coli K-124.58
30S ribosomal protein S19Escherichia coli K-124.58
30S ribosomal protein S20Escherichia coli K-124.58
30S ribosomal protein S2Escherichia coli K-124.58
30S ribosomal protein S3Escherichia coli K-124.58
30S ribosomal protein S4Escherichia coli K-124.58
30S ribosomal protein S5Escherichia coli K-124.58
30S ribosomal protein S8Escherichia coli K-124.58
30S ribosomal protein S9Escherichia coli K-124.58
50S ribosomal protein L13Escherichia coli K-124.58
50S ribosomal protein L14Escherichia coli K-124.58
50S ribosomal protein L16Escherichia coli K-124.58
50S ribosomal protein L23Escherichia coli K-124.58
30S ribosomal protein S15Escherichia coli K-124.58
50S ribosomal protein L17Escherichia coli K-124.58
50S ribosomal protein L21Escherichia coli K-124.58
50S ribosomal protein L30Escherichia coli K-124.58
50S ribosomal protein L6Escherichia coli K-124.58
30S ribosomal protein S14Escherichia coli K-124.58
30S ribosomal protein S17Escherichia coli K-124.58
30S ribosomal protein S1Escherichia coli K-124.58
50S ribosomal protein L18Escherichia coli K-124.58
Alpha-synucleinHomo sapiens (human)6.06
50S ribosomal protein L2Escherichia coli K-124.58
50S ribosomal protein L3Escherichia coli K-124.58
50S ribosomal protein L24Escherichia coli K-124.58
50S ribosomal protein L4Escherichia coli K-124.58
50S ribosomal protein L22Escherichia coli K-124.58
50S ribosomal protein L5Escherichia coli K-124.58
30S ribosomal protein S21Escherichia coli K-124.58
50S ribosomal protein L25Escherichia coli K-124.58
50S ribosomal protein L36 2Escherichia coli K-124.58

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199015 (48.39)18.7374
1990's0 (0.00)18.2507
2000's6 (19.35)29.6817
2010's10 (32.26)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Glen, RC; Lowe, R; Mitchell, JB1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Forster, RK; Rebell, G; Stiles, W1
Bosseckert, VH1
Brettschneider, I; Krecí, L; Praus, R1
Black, O; Singh, M; Webster, PD1
Baving, G; Reichel, G; Ulmer, WT1
af Björksten, K; Gothoni, G; Hackman, R; Pentikäinen, P; Vapaatalo, HI1
Ciani, A; Fontana, G1
Honegger, H1
Tsvetkov, VL; Williams, PH1
VOLYNSKAIA, SL1
HADIDIAN, L; KOUSSA, M; SCHWABE, CW1
CHADWICK, DA; JENNINGS, RC1
JAIN, BS; NATH, J; SRIVASTAVA, KN1
RICHARDS, AG1

Reviews

1 review(s) available for atropine and tetracycline

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

30 other study(ies) available for atropine and tetracycline

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Recurrent keratitis due to Acremonium potronii.
    American journal of ophthalmology, 1975, Volume: 79, Issue:1

    Topics: Adolescent; Atropine; Bacitracin; Corneal Injuries; Corneal Ulcer; Cyanoacrylates; Eye Injuries; Gentamicins; Histamine H1 Antagonists; Humans; Keratitis; Male; Mycoses; Natamycin; Neomycin; Polymyxins; Prednisolone; Recurrence; Tetracycline; Wound Healing

1975
[Possibilities of current diagnosis of pancreatic diseases and conservative therapy].
    Zentralblatt fur Chirurgie, 1976, Volume: 101, Issue:5

    Topics: Amylases; Aprotinin; Atropine; Clinical Enzyme Tests; Diuretics; Humans; Lipase; Pancreatic Diseases; Pancreatitis; Radionuclide Imaging; Tetracycline

1976
Hydrophilic gel contact lenses as a new drug delivery system in ophthalmology and as therapeutic bandage lenses.
    Acta Universitatis Carolinae. Medica, 1975, Volume: 21, Issue:5-6

    Topics: Animals; Atropine; Bandages; Cocaine; Contact Lenses, Hydrophilic; Cortisone; Epinephrine; Eye Diseases; Fluoresceins; Gels; Humans; Neomycin; Neostigmine; Pharmaceutical Preparations; Pilocarpine; Rabbits; Scopolamine; Tetracycline; Time Factors

1975
Effect of drugs on pancreatic amylase secretion in vitro.
    Gastroenterology, 1972, Volume: 63, Issue:3

    Topics: Amphotericin B; Amylases; Animals; Anti-Bacterial Agents; Atropine; Bethanechol Compounds; Cell Membrane Permeability; Cyanides; Dactinomycin; In Vitro Techniques; Lidocaine; Pancreas; Puromycin; Rats; Streptomycin; Tetracycline; Time Factors; Valinomycin

1972
Drugs in breast milk.
    The Medical letter on drugs and therapeutics, 1974, Mar-15, Volume: 16, Issue:6

    Topics: Anticoagulants; Anticonvulsants; Antineoplastic Agents; Antithyroid Agents; Aspirin; Atropine; Caffeine; Chloramphenicol; Chlorothiazide; Contraceptives, Oral; Ergot Alkaloids; Ethanol; Female; Humans; Hypnotics and Sedatives; Methadone; Milk, Human; Nalidixic Acid; Narcotics; Penicillins; Quinine; Reserpine; Sulfonamides; Tetracycline

1974
Physiopathological considerations in the treatment of coal workers' pneumoconiosis.
    Annals of the New York Academy of Sciences, 1972, Dec-29, Volume: 200

    Topics: Acetylcholine; Airway Obstruction; Airway Resistance; Atropine; Blood Pressure; Bronchitis; Bronchodilator Agents; Chronic Disease; Coal Mining; Drug Combinations; Dyspnea; Humans; Metaproterenol; Pneumoconiosis; Prednisolone; Pulmonary Artery; Tetracycline

1972
Absorption of antibiotics: influence of metoclopramide and atropine on serum levels of pivampicillin and tetracycline.
    Annals of clinical research, 1972, Volume: 4, Issue:4

    Topics: Ampicillin; Animals; Anisoles; Antiemetics; Atropine; Bacillus subtilis; Benzamides; Biological Assay; Depression, Chemical; Drug Interactions; Ethylamines; Gastrointestinal Motility; Humans; Injections, Intramuscular; Injections, Subcutaneous; Intestinal Absorption; Male; Propionates; Rats; Sarcina; Stimulation, Chemical; Tetracycline; Time Factors

1972
[A case of parotid fistula present for more than 20 years].
    Rivista italiana di stomatologia, 1969, Jun-06, Volume: 24, Issue:6

    Topics: Adult; Atropine; Humans; Male; Mastoid; Parotid Gland; Radiography; Salivary Gland Diseases; Salivary Gland Fistula; Tetracycline

1969
[The effect of externally used drugs on the corneal endothelium].
    Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1965, Dec-14, Volume: 168, Issue:6

    Topics: Anesthetics, Local; Animals; Atropine; Chloramphenicol; Cocaine; Cornea; Dexamethasone; Hydrocortisone; Parathion; Rabbits; Tetracycline

1965
Bilateral spontaneous expulsion of the lens in a case of Kwashiorkor.
    The Journal of tropical medicine and hygiene, 1969, Volume: 72, Issue:2

    Topics: Atropine; Child, Preschool; Corneal Dystrophies, Hereditary; Eye Diseases; Female; Humans; Keratitis; Kwashiorkor; Lens, Crystalline; Tetracycline; Vitamin A Deficiency

1969
[On the decrease in the irritating effect of tetracycline on the intestinal interoceptors induced by novocaine, atropine and ekmolin].
    Antibiotiki, 1963, Volume: 8

    Topics: Atropine; Intestines; Liver Extracts; Nerve Endings; Procaine; Protamines; Sensory Receptor Cells; Tetracycline

1963
HOST-PARASITE RELATIONSHIPS IN ECHINOCOCCOSIS. IX. IN VITRO SURVIVAL OF HYDATID SCOLICES AND THE EFFECTS OF DRUGS UPON SCOLEX RESPIRATION.
    The American journal of tropical medicine and hygiene, 1963, Volume: 12

    Topics: Acridines; Animals; Anti-Bacterial Agents; Antimony; Atropine; Culture Media; Diethylcarbamazine; Echinococcosis; Echinococcus; Emetine; Gentian Violet; Host-Parasite Interactions; In Vitro Techniques; Metabolism; Oxytetracycline; Physostigmine; Research; Temperature; Tetracycline

1963
MASSIVE HEPATIC NECROSIS ASSOCIATED WITH HALOTHANE ANESTHESIA.
    Lancet (London, England), 1964, Apr-11, Volume: 1, Issue:7337

    Topics: Anesthesia; Atropine; Barbiturates; Chemical and Drug Induced Liver Injury; Colonic Neoplasms; Halothane; Hepatitis; Massive Hepatic Necrosis; Necrosis; Neomycin; Phenazocine; Postoperative Complications; Promethazine; Sigmoidoscopy; Surgical Procedures, Operative; Tetracycline; Toxicology

1964
MANAGEMENT OF HERPES ZOSTER OPHTHALMICUS. A CLINICAL STUDY OF 78 CASES.
    Journal of the Indian Medical Association, 1964, Feb-01, Volume: 42

    Topics: Adolescent; Atropa belladonna; Atropine; Chickenpox; Child; Cornea; Ergotamine; Geriatrics; Herpes Zoster; Herpes Zoster Ophthalmicus; Herpesvirus 3, Human; Humans; Hydrocortisone; India; Iridocyclitis; Neuralgia; Oxytetracycline; Penicillins; Physiology; Tetracycline; Toxicology

1964
MALATHION POISONING SUCCESSFULLY TREATED WITH LARGE DOSES OF ATROPINE.
    Canadian Medical Association journal, 1964, Jul-11, Volume: 91

    Topics: Anti-Bacterial Agents; Atropine; Chloramphenicol; Cholinesterases; Depression; Depressive Disorder; Escherichia coli Infections; Malathion; Metabolism; Neurologic Manifestations; Organophosphate Poisoning; Oximes; Penicillins; Pharmacology; Phosphorus; Poisons; Pralidoxime Compounds; Prednisone; Pyridines; Streptomycin; Suicide; Tetracycline; Toxicology

1964