atropine has been researched along with sulfasalazine in 15 studies
| Studies (atropine) | Trials (atropine) | Recent Studies (post-2010) (atropine) | Studies (sulfasalazine) | Trials (sulfasalazine) | Recent Studies (post-2010) (sulfasalazine) |
|---|---|---|---|---|---|
| 26,711 | 1,259 | 1,697 | 4,437 | 585 | 938 |
| Protein | Taxonomy | atropine (IC50) | sulfasalazine (IC50) |
|---|---|---|---|
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | 1.5 | |
| Solute carrier organic anion transporter family member 2B1 | Homo sapiens (human) | 3 | |
| Carbonic anhydrase 1 | Homo sapiens (human) | 3.04 | |
| Carbonic anhydrase 2 | Homo sapiens (human) | 4.49 | |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | 6.332 | |
| Sodium/bile acid cotransporter | Homo sapiens (human) | 9.6 | |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 0.46 | |
| Cystine/glutamate transporter | Homo sapiens (human) | 0.16 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 0.56 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (33.33) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 6 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Haga, K; Kawazoe, Y; Mizuta, H; Ogawa, K; Yokobe, T | 1 |
| Neugebauer, A; Terhaag, B | 1 |
| Tumen, HJ | 1 |
| Brandborg, LL; Goldberg, HI; Moss, AA; Pepper, HW; Shanser, JD | 1 |
| Hansen, W | 1 |
| Amstutz, I; Diener, M | 1 |
2 review(s) available for atropine and sulfasalazine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Dietary and drug therapy of intestinal disease].
Topics: Aerophagy; Anti-Inflammatory Agents; Atropine; beta-Galactosidase; Cathartics; Colitis, Ulcerative; Colonic Diseases, Functional; Constipation; Crohn Disease; Diarrhea; Dietary Fiber; Flatulence; Food, Formulated; Gastrointestinal Motility; Glutens; Humans; Intestinal Diseases; Malabsorption Syndromes; Metoclopramide; Parenteral Nutrition; Substance-Related Disorders; Sulfasalazine; Water-Electrolyte Imbalance | 1980 |
13 other study(ies) available for atropine and sulfasalazine
| Article | Year |
|---|---|
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
[Determination of small intestinal transit time in beagle dogs using salicylazosulfapyridine].
Topics: Animals; Atropine; Dogs; Female; Intestinal Absorption; Intestine, Small; Sulfasalazine; Time Factors | 1989 |
[Modification of orocecal transit time of salazosulfapyridine by atropine and metoclopramide in healthy probands].
Topics: Adult; Atropine; Gastrointestinal Motility; Humans; Intestinal Absorption; Kinetics; Male; Metoclopramide; Sulfasalazine | 1986 |
The drug therapy of ulcerative colitis and of Crohn's disease.
Topics: Adrenocorticotropic Hormone; Atropine; Azathioprine; Colitis, Ulcerative; Crohn Disease; Diarrhea; Diet; Glucocorticoids; Humans; Immunosuppressive Agents; Mercaptopurine; Nutrition Disorders; Pain; Prednisolone; Prednisone; Sulfasalazine | 1974 |
Collagenous sprue.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Animals; Atropine; Biopsy; Celiac Disease; Collagen; Diet Therapy; Drug Combinations; Glutens; Humans; Intestinal Mucosa; Isonipecotic Acids; Jejunum; Male; Milk; Prednisone; Radiography; Sulfasalazine | 1974 |
Inhibition of antigen-induced muscle contractions by inhibitors of thromboxane pathway in rat small intestine.
Topics: Animals; Antigens; Atropine; Benzimidazoles; Benzoxepins; Carbachol; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Female; Hexamethonium; Histamine H1 Antagonists; Imidazoles; Intestine, Small; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Ovalbumin; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Rats, Zucker; Receptors, Thromboxane; Sulfasalazine; Sulfonamides; Tetrodotoxin; Thromboxanes | 1997 |