Page last updated: 2024-09-05

atropine and sufentanil

atropine has been researched along with sufentanil in 23 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(sufentanil)
Trials
(sufentanil)
Recent Studies (post-2010) (sufentanil)
26,7111,2591,6972,156956678

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)sufentanil (IC50)
ATP-dependent translocase ABCB1Homo sapiens (human)4.5
Delta-type opioid receptorRattus norvegicus (Norway rat)0.0023
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0014
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.0023
Sigma non-opioid intracellular receptor 1Cavia porcellus (domestic guinea pig)2.077

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.70)18.7374
1990's6 (26.09)18.2507
2000's6 (26.09)29.6817
2010's7 (30.43)24.3611
2020's2 (8.70)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Gintzler, AR; Xu, H1
el-Ganzouri, AR; Ivankovich, AD; Sathoff, RH; Spiess, BD1
Monk, TG; Smith, I; White, PF1
Archer, D; Ecoffey, C; Goutallier, D; Jamali, S; Parker, F; Ravussin, P1
Archer, D; Bonnafous, M; David, P; Ecoffey, C; Jamali, S; Ravussin, P1
Brichant, JF; Cantraine, F; Coussaert, E; Dewandre, PY; Grevesse, M; Hans, P; Lamy, M1
Born, JD; Brichant, JF; Dewandre, PY; Hans, P; Lamy, M1
Fruhwald, S; Hammer, HF; Herk, E; Holzer, P; Metzler, H1
Cardinal, V; Claprood, Y; Colas, MJ; Gagnon, L; Martin, R; Tétrault, JP1
Blary, S; Caeymaex, L; Carbajal, R; Dahan, S; Dassieu, G; Delorme, P; Durrmeyer, X1
Alexandre, C; Beuchée, A; Breinig, S; Claris, O; Danan, C; Dechartres, A; Durrmeyer, X; Jung, C; Levy, C; Marchand-Martin, L; Marcoux, MO; Saliba, E; Tourneux, P1
Fideler, F; Grasshoff, C1
Ayachi, A; Carbajal, R; Chabernaud, JL; Chouakri, O; Cimerman, P; Courtois, E; Henry-Larzul, V; Kessous, K; Lode, N; Normand, A; Rousseau, J1
Buisman, PL; Kalmar, AF; Poterman, M; Scheeren, TWL; Struys, MMRF1
Alexandre, C; Breinig, S; Claris, O; Dechartres, A; Durrmeyer, X; Jung, C; Lebeaux, C; Levy, C; Marchand-Martin, L; Tauzin, M; Tourneux, P1

Reviews

1 review(s) available for atropine and sufentanil

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

8 trial(s) available for atropine and sufentanil

ArticleYear
Comparison of transesophageal atrial pacing with anticholinergic drugs for the treatment of intraoperative bradycardia.
    Anesthesia and analgesia, 1994, Volume: 78, Issue:2

    Topics: Aged; Anesthesia, General; Atropine; Bradycardia; Cardiac Pacing, Artificial; Glycopyrrolate; Heart Rate; Humans; Incidence; Intraoperative Complications; Isoflurane; Male; Middle Aged; Nitrous Oxide; Prospective Studies; Sufentanil; Vecuronium Bromide

1994
The effects of bolus administration of opioids on cerebrospinal fluid pressure in patients with supratentorial lesions.
    Anesthesia and analgesia, 1996, Volume: 82, Issue:3

    Topics: Adult; Aged; Anesthetics, Inhalation; Anti-Arrhythmia Agents; Atropine; Blood Pressure; Bradycardia; Cerebral Arteries; Cerebrospinal Fluid Pressure; Double-Blind Method; Fentanyl; Heart Rate; Homeostasis; Humans; Hypotension; Injections, Intravenous; Isoflurane; Middle Aged; Phenylephrine; Placebos; Prospective Studies; Respiration, Artificial; Sufentanil; Supratentorial Neoplasms; Treatment Outcome; Vasoconstrictor Agents; Vasodilation

1996
The effect of skull-pin insertion on cerebrospinal fluid pressure and cerebral perfusion pressure: influence of sufentanil and fentanyl.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:6

    Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Adult; Analgesics, Opioid; Atropine; Blood Pressure; Bone Nails; Cerebrospinal Fluid Pressure; Cerebrovascular Circulation; Craniotomy; Double-Blind Method; Fentanyl; Heart Rate; Humans; Injections, Intravenous; Intracranial Pressure; Perfusion; Phenylephrine; Prospective Studies; Skull; Sufentanil

1997
Effects of two calculated plasma sufentanil concentrations on the hemodynamic and bispectral index responses to Mayfield head holder application.
    Journal of neurosurgical anesthesiology, 1999, Volume: 11, Issue:2

    Topics: Alprazolam; Anesthesia, Intravenous; Anesthetics, Intravenous; Atropine; Blood Pressure; Brain; Female; Heart Rate; Hemodynamics; Humans; Hydroxyzine; Male; Middle Aged; Multivariate Analysis; Neurosurgical Procedures; Premedication; Propofol; Sufentanil; Time Factors

1999
[Severe bradycardia and asystole with low dose sufentanil during induction with sevoflurane: a report of three cases].
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2004, Volume: 51, Issue:8

    Topics: Adult; Anesthetics, Combined; Anesthetics, Inhalation; Anesthetics, Intravenous; Atropine; Bradycardia; Bronchodilator Agents; Dose-Response Relationship, Drug; Drug Interactions; Female; Heart Arrest; Heart Rate; Humans; Methyl Ethers; Middle Aged; Randomized Controlled Trials as Topic; Severity of Illness Index; Sevoflurane; Sufentanil

2004
Effect of Atropine With Propofol vs Atropine With Atracurium and Sufentanil on Oxygen Desaturation in Neonates Requiring Nonemergency Intubation: A Randomized Clinical Trial.
    JAMA, 2018, 05-01, Volume: 319, Issue:17

    Topics: Adjuvants, Anesthesia; Analgesics; Atracurium; Atropine; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Heart Rate; Humans; Infant, Newborn; Intensive Care Units, Neonatal; Intubation, Intratracheal; Oxygen; Propofol; Sufentanil

2018
Improved haemodynamic stability and cerebral tissue oxygenation after induction of anaesthesia with sufentanil compared to remifentanil: a randomised controlled trial.
    BMC anesthesiology, 2020, 10-07, Volume: 20, Issue:1

    Topics: Aged; Anesthesia; Atropine; Brain; Coronary Artery Bypass; Double-Blind Method; Female; Hemodynamics; Humans; Male; Middle Aged; Oxygen; Prospective Studies; Remifentanil; Sufentanil

2020
Neurodevelopmental Outcomes after Premedication with Atropine/Propofol vs Atropine/Atracurium/Sufentanil for Neonatal Intubation: 2-Year Follow-Up of a Randomized Clinical Trial.
    The Journal of pediatrics, 2021, Volume: 231

    Topics: Adjuvants, Anesthesia; Anesthetics, Combined; Atracurium; Atropine; Child, Preschool; Double-Blind Method; Female; Follow-Up Studies; Humans; Infant, Newborn; Intubation, Intratracheal; Male; Nervous System; Propofol; Sufentanil; Time Factors; Treatment Outcome

2021

Other Studies

14 other study(ies) available for atropine and sufentanil

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Opioid enhancement of evoked [Met5]enkephalin release requires activation of cholinergic receptors: possible involvement of intracellular calcium.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Mar-01, Volume: 89, Issue:5

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Atropine; Calcimycin; Calcium; Colforsin; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Evoked Potentials; Fentanyl; Guinea Pigs; Hexamethonium Compounds; In Vitro Techniques; Myenteric Plexus; Naloxone; Pyrrolidines; Receptors, Muscarinic; Receptors, Opioid; Sufentanil

1992
High-dose sufentanil: four cases of sudden hypotension on induction.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:6

    Topics: Adult; Aged; Atropine; Blood Pressure; Cardiac Surgical Procedures; Ephedrine; Epinephrine; Female; Fentanyl; Heart Rate; Humans; Hypotension; Male; Middle Aged; Sufentanil

1986
Effects of target-controlled anesthesia with propofol and sufentanil on the hemodynamic response to Mayfield head holder application.
    Acta anaesthesiologica Belgica, 1998, Volume: 49, Issue:1

    Topics: Adjuvants, Anesthesia; Alprazolam; Analysis of Variance; Anesthesia, Intravenous; Anesthetics, Intravenous; Atracurium; Atropine; Blood Pressure; Brain; Heart Rate; Humans; Hydroxyzine; Hypnotics and Sedatives; Hypotension; Infusion Pumps; Middle Aged; Neuromuscular Blockade; Neuromuscular Nondepolarizing Agents; Neurosurgery; Pain; Preanesthetic Medication; Propofol; Sufentanil

1998
Differential reversal of drug-induced small bowel paralysis by cerulein and neostigmine.
    Intensive care medicine, 2004, Volume: 30, Issue:7

    Topics: Adjuvants, Anesthesia; Adrenergic Agonists; Animals; Atropine; Ceruletide; Dose-Response Relationship, Drug; Epinephrine; Female; Ganglionic Blockers; Guinea Pigs; Hexamethonium; In Vitro Techniques; Intestine, Small; Male; Neostigmine; Paralysis; Parasympathomimetics; Peristalsis; Sufentanil

2004
Assessment of atropine-sufentanil-atracurium anaesthesia for endotracheal intubation: an observational study in very premature infants.
    BMC pediatrics, 2014, May-07, Volume: 14

    Topics: Adjuvants, Anesthesia; Atracurium; Atropine; Blood Pressure; Carbon Dioxide; Drug Therapy, Combination; Female; Heart Rate; Humans; Infant, Newborn; Infant, Premature; Intensive Care Units, Neonatal; Intubation, Intratracheal; Male; Neuromuscular Nondepolarizing Agents; Oximetry; Oxygen; Pain; Premedication; Prospective Studies; Sufentanil

2014
Premedication for Neonates Requiring Nonemergency Intubation.
    JAMA, 2018, 09-18, Volume: 320, Issue:11

    Topics: Atracurium; Atropine; Humans; Infant, Newborn; Intubation; Intubation, Intratracheal; Oxygen; Premedication; Propofol; Sufentanil

2018
Premedication practices for tracheal intubation in neonates transported by French medical transport teams: a prospective observational study.
    BMJ open, 2019, 11-14, Volume: 9, Issue:11

    Topics: Analgesics, Opioid; Atropine; Female; Humans; Infant, Newborn; Intensive Care Units, Neonatal; Intubation, Intratracheal; Male; Midazolam; Pain; Paris; Premedication; Prospective Studies; Sufentanil

2019