Protein | Taxonomy | atropine (IC50) | staurosporine (IC50) |
Chain A, Glycogen Synthase Kinase-3 Beta | Homo sapiens (human) | | 0.015 |
Chain B, Glycogen Synthase Kinase-3 Beta | Homo sapiens (human) | | 0.015 |
Chain A, Glycogen Synthase Kinase-3 Beta | Homo sapiens (human) | | 0.015 |
Chain A, Tyrosine-protein kinase ZAP-70 | Homo sapiens (human) | | 0.0558 |
Chain A, Tyrosine-protein kinase SYK | Homo sapiens (human) | | 0.012 |
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1 | Homo sapiens (human) | | 0.01 |
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1 | Homo sapiens (human) | | 0.01 |
Chain X, Proto-oncogene tyrosine-protein kinase Fyn | Homo sapiens (human) | | 0.0048 |
Chain A, Serine/threonine-protein kinase TAO2 | Rattus norvegicus (Norway rat) | | 3 |
epidermal growth factor receptor isoform a precursor | Homo sapiens (human) | | 0.4467 |
Serine/threonine-protein kinase Sgk1 | Homo sapiens (human) | | 0.01 |
Cell division cycle 7-related protein kinase | Homo sapiens (human) | | 0.0549 |
Serine/threonine-protein kinase PLK4 | Homo sapiens (human) | | 0.0083 |
Serine/threonine-protein kinase 25 | Homo sapiens (human) | | 0.0029 |
Citron Rho-interacting kinase | Homo sapiens (human) | | 0.749 |
Dual specificity mitogen-activated protein kinase kinase 7 | Homo sapiens (human) | | 0.9255 |
Telomerase reverse transcriptase | Homo sapiens (human) | | 6.9517 |
Serine/threonine-protein kinase Chk1 | Homo sapiens (human) | | 0.1772 |
Inhibitor of nuclear factor kappa-B kinase subunit beta | Homo sapiens (human) | | 0.5561 |
Aurora kinase A | Homo sapiens (human) | | 0.0087 |
Cyclin-G-associated kinase | Homo sapiens (human) | | 0.011 |
Serine/threonine-protein kinase DCLK1 | Homo sapiens (human) | | 0.267 |
Inhibitor of nuclear factor kappa-B kinase subunit alpha | Homo sapiens (human) | | 0.1265 |
Muscle, skeletal receptor tyrosine-protein kinase | Homo sapiens (human) | | 0.1161 |
Mitogen-activated protein kinase 13 | Homo sapiens (human) | | 0.4137 |
3-phosphoinositide-dependent protein kinase 1 | Homo sapiens (human) | | 0.0072 |
Death-associated protein kinase 3 | Homo sapiens (human) | | 0.0026 |
Mitogen-activated protein kinase kinase kinase 7 | Homo sapiens (human) | | 0.0565 |
Receptor-interacting serine/threonine-protein kinase 2 | Homo sapiens (human) | | 0.356 |
Dual specificity tyrosine-phosphorylation-regulated kinase 3 | Homo sapiens (human) | | 0.0231 |
NUAK family SNF1-like kinase 1 | Homo sapiens (human) | | 0.003 |
Cyclin-T1 | Homo sapiens (human) | | 0.0118 |
Cyclin-T2 | Homo sapiens (human) | | 0.0038 |
Tyrosine-protein kinase JAK2 | Homo sapiens (human) | | 0.0016 |
Rho-associated protein kinase 2 | Homo sapiens (human) | | 0.0045 |
Serine/threonine-protein kinase ULK1 | Homo sapiens (human) | | 0.0096 |
Serine/threonine-protein kinase/endoribonuclease IRE1 | Homo sapiens (human) | | 0.1246 |
Ribosomal protein S6 kinase alpha-5 | Homo sapiens (human) | | 0.0011 |
Ribosomal protein S6 kinase alpha-4 | Homo sapiens (human) | | 0.0071 |
Serine/threonine-protein kinase 16 | Homo sapiens (human) | | 0.2385 |
Cyclin-K | Homo sapiens (human) | | 0.0948 |
Serine/threonine-protein kinase PAK 3 | Homo sapiens (human) | | 0.0003 |
Serine/threonine-protein kinase 17B | Homo sapiens (human) | | 0.0258 |
Serine/threonine-protein kinase 10 | Homo sapiens (human) | | 0.008 |
Serine/threonine-protein kinase D3 | Homo sapiens (human) | | 0.1446 |
Cyclin-dependent kinase 14 | Homo sapiens (human) | | 0.1145 |
G2/mitotic-specific cyclin-B2 | Homo sapiens (human) | | 0.0107 |
Mitogen-activated protein kinase kinase kinase 6 | Homo sapiens (human) | | 0.2829 |
Mitogen-activated protein kinase kinase kinase kinase 4 | Homo sapiens (human) | | 0.0005 |
Serine/threonine-protein kinase LATS1 | Homo sapiens (human) | | 0.013 |
Serine/threonine-protein kinase PAK 4 | Homo sapiens (human) | | 0.0132 |
Serine/threonine-protein kinase Chk2 | Homo sapiens (human) | | 0.0212 |
G1/S-specific cyclin-E2 | Homo sapiens (human) | | 0.011 |
cAMP-dependent protein kinase catalytic subunit alpha | Bos taurus (cattle) | | 0.0812 |
Tyrosine-protein kinase ABL1 | Homo sapiens (human) | | 0.1233 |
Proto-oncogene tyrosine-protein kinase Src | Gallus gallus (chicken) | | 0.0063 |
Epidermal growth factor receptor | Homo sapiens (human) | | 0.083 |
RAF proto-oncogene serine/threonine-protein kinase | Homo sapiens (human) | | 0.1281 |
Receptor tyrosine-protein kinase erbB-2 | Homo sapiens (human) | | 0.0713 |
High affinity nerve growth factor receptor | Homo sapiens (human) | | 0.2403 |
Protein kinase C gamma type | Homo sapiens (human) | | 0.1167 |
Platelet-derived growth factor receptor beta | Mus musculus (house mouse) | | 0.002 |
Protein kinase C alpha type | Rattus norvegicus (Norway rat) | | 0.2327 |
Protein kinase C beta type | Homo sapiens (human) | | 0.0684 |
Prostaglandin G/H synthase 1 | Ovis aries (sheep) | | 0.056 |
Insulin receptor | Homo sapiens (human) | | 0.0706 |
Tyrosine-protein kinase Lck | Homo sapiens (human) | | 0.1784 |
Tyrosine-protein kinase Fyn | Homo sapiens (human) | | 0.0929 |
Retinoblastoma-associated protein | Homo sapiens (human) | | 0.066 |
Cyclin-dependent kinase 1 | Homo sapiens (human) | | 0.0075 |
Tyrosine-protein kinase Fes/Fps | Homo sapiens (human) | | 0.0039 |
Macrophage colony-stimulating factor 1 receptor | Homo sapiens (human) | | 0.1269 |
Tyrosine-protein kinase Yes | Homo sapiens (human) | | 0.0029 |
Tyrosine-protein kinase Lyn | Homo sapiens (human) | | 0.0012 |
Proto-oncogene tyrosine-protein kinase receptor Ret | Homo sapiens (human) | | 0.0021 |
Insulin-like growth factor 1 receptor | Homo sapiens (human) | | 0.5534 |
Hepatocyte growth factor receptor | Homo sapiens (human) | | 0.1917 |
Tyrosine-protein kinase HCK | Homo sapiens (human) | | 0.0025 |
Proto-oncogene tyrosine-protein kinase ROS | Homo sapiens (human) | | 0.0004 |
Protein kinase C delta type | Rattus norvegicus (Norway rat) | | 0.274 |
Protein kinase C epsilon type | Rattus norvegicus (Norway rat) | | 0.274 |
Protein kinase C zeta type | Rattus norvegicus (Norway rat) | | 0.274 |
Platelet-derived growth factor receptor beta | Homo sapiens (human) | | 0.3707 |
Tyrosine-protein kinase Fgr | Homo sapiens (human) | | 0.0009 |
Cytochrome P450 2D6 | Homo sapiens (human) | | 0.0002 |
Mast/stem cell growth factor receptor Kit | Homo sapiens (human) | | 0.0412 |
Breakpoint cluster region protein | Homo sapiens (human) | | 0.0945 |
Calcium/calmodulin-dependent protein kinase type II subunit alpha | Rattus norvegicus (Norway rat) | | 0.059 |
Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | | 0.0216 |
Fibroblast growth factor receptor 1 | Homo sapiens (human) | | 0.0699 |
Cyclin-dependent kinase 1 | Mus musculus (house mouse) | | 0.008 |
Cyclin-dependent kinase 4 | Homo sapiens (human) | | 0.0429 |
Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | | 0.3642 |
Acyl-CoA desaturase 1 | Mus musculus (house mouse) | | 3.4 |
Insulin receptor-related protein | Homo sapiens (human) | | 0.0113 |
G2/mitotic-specific cyclin-B1 | Homo sapiens (human) | | 0.0088 |
Dipeptidyl peptidase 4 | Rattus norvegicus (Norway rat) | | 0.003 |
5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | | 4 |
Serine/threonine-protein kinase B-raf | Homo sapiens (human) | | 0.0107 |
Insulin receptor | Mus musculus (house mouse) | | 0.2 |
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform | Homo sapiens (human) | | 0.0004 |
Platelet-derived growth factor receptor alpha | Homo sapiens (human) | | 0.0007 |
Tyrosine-protein kinase Fer | Homo sapiens (human) | | 0.0008 |
Protein kinase C alpha type | Homo sapiens (human) | | 0.0655 |
cAMP-dependent protein kinase catalytic subunit alpha | Homo sapiens (human) | | 0.0115 |
Vascular endothelial growth factor receptor 1 | Homo sapiens (human) | | 0.0149 |
Cytochrome P450 11B2, mitochondrial | Homo sapiens (human) | | 0.011 |
Interferon-induced, double-stranded RNA-activated protein kinase | Homo sapiens (human) | | 0.1 |
Amine oxidase [flavin-containing] B | Rattus norvegicus (Norway rat) | | 0.0025 |
Casein kinase II subunit alpha' | Homo sapiens (human) | | 2.0215 |
Cyclin-A2 | Homo sapiens (human) | | 0.009 |
Cannabinoid receptor 1 | Rattus norvegicus (Norway rat) | | 0.01 |
Serine/threonine-protein kinase MAK | Homo sapiens (human) | | 0.0257 |
Ephrin type-A receptor 1 | Homo sapiens (human) | | 0.0947 |
Fibroblast growth factor receptor 2 | Homo sapiens (human) | | 0.0504 |
Receptor tyrosine-protein kinase erbB-3 | Homo sapiens (human) | | 0.0106 |
Fibroblast growth factor receptor 4 | Homo sapiens (human) | | 0.17 |
Fibroblast growth factor receptor 3 | Homo sapiens (human) | | 0.0554 |
cAMP-dependent protein kinase catalytic subunit gamma | Homo sapiens (human) | | 0.0137 |
Cyclin-O | Homo sapiens (human) | | 0.0015 |
cAMP-dependent protein kinase catalytic subunit beta | Homo sapiens (human) | | 0.0148 |
Ribosomal protein S6 kinase beta-1 | Homo sapiens (human) | | 0.0007 |
Tyrosine-protein kinase JAK1 | Homo sapiens (human) | | 0.004 |
Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | | 0.028 |
G1/S-specific cyclin-D1 | Homo sapiens (human) | | 0.0355 |
Protein kinase C eta type | Homo sapiens (human) | | 0.1165 |
Cyclin-C | Homo sapiens (human) | | 0.0105 |
G1/S-specific cyclin-E1 | Homo sapiens (human) | | 0.0108 |
Cyclin-dependent kinase 2 | Homo sapiens (human) | | 0.0073 |
Beta-adrenergic receptor kinase 1 | Homo sapiens (human) | | 1.1595 |
Platelet-derived growth factor receptor alpha | Mus musculus (house mouse) | | 0.002 |
Mitogen-activated protein kinase 3 | Homo sapiens (human) | | 4.6724 |
MAP/microtubule affinity-regulating kinase 3 | Homo sapiens (human) | | 0.0004 |
cAMP-dependent protein kinase catalytic subunit alpha | Rattus norvegicus (Norway rat) | | 0.055 |
Mitogen-activated protein kinase 1 | Homo sapiens (human) | | 2.6853 |
Ephrin type-A receptor 2 | Homo sapiens (human) | | 0.1257 |
Ephrin type-A receptor 3 | Homo sapiens (human) | | 0.0347 |
Ephrin type-A receptor 8 | Homo sapiens (human) | | 0.1061 |
Ephrin type-B receptor 2 | Homo sapiens (human) | | 0.1191 |
Leukocyte tyrosine kinase receptor | Homo sapiens (human) | | 0.0173 |
Non-receptor tyrosine-protein kinase TYK2 | Homo sapiens (human) | | 0.0137 |
G1/S-specific cyclin-D3 | Homo sapiens (human) | | 0.055 |
Tyrosine-protein kinase receptor UFO | Homo sapiens (human) | | 0.0131 |
RAC-alpha serine/threonine-protein kinase | Homo sapiens (human) | | 0.1848 |
RAC-beta serine/threonine-protein kinase | Homo sapiens (human) | | 0.4119 |
G protein-coupled receptor kinase 4 | Homo sapiens (human) | | 0.0914 |
Kinesin-1 heavy chain | Homo sapiens (human) | | 0.0015 |
G protein-coupled receptor kinase 5 | Homo sapiens (human) | | 0.0489 |
Hexokinase-4 | Homo sapiens (human) | | 0.0006 |
Beta-adrenergic receptor kinase 2 | Homo sapiens (human) | | 0.856 |
Vascular endothelial growth factor receptor 3 | Homo sapiens (human) | | 0.0146 |
Vascular endothelial growth factor receptor 2 | Homo sapiens (human) | | 0.1791 |
Dual specificity mitogen-activated protein kinase kinase 2 | Homo sapiens (human) | | 0.026 |
Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | | 0.0014 |
Bone morphogenetic protein receptor type-1A | Homo sapiens (human) | | 4.288 |
Activin receptor type-1B | Homo sapiens (human) | | 9.118 |
TGF-beta receptor type-1 | Homo sapiens (human) | | 2.2823 |
Serine/threonine-protein kinase receptor R3 | Homo sapiens (human) | | 0.85 |
Tyrosine-protein kinase CSK | Homo sapiens (human) | | 0.2071 |
Protein kinase C iota type | Homo sapiens (human) | | 0.1739 |
Megakaryocyte-associated tyrosine-protein kinase | Homo sapiens (human) | | 0.442 |
Tyrosine-protein kinase Tec | Homo sapiens (human) | | 0.0338 |
Tyrosine-protein kinase TXK | Homo sapiens (human) | | 0.0203 |
Tyrosine-protein kinase ABL2 | Homo sapiens (human) | | 0.0505 |
Tyrosine-protein kinase FRK | Homo sapiens (human) | | 0.0108 |
G protein-coupled receptor kinase 6 | Homo sapiens (human) | | 0.0473 |
Tyrosine-protein kinase ZAP-70 | Homo sapiens (human) | | 0.0175 |
Tyrosine-protein kinase SYK | Homo sapiens (human) | | 0.0057 |
Mitogen-activated protein kinase 8 | Homo sapiens (human) | | 1.1067 |
Mitogen-activated protein kinase 9 | Homo sapiens (human) | | 2.0555 |
Dual specificity mitogen-activated protein kinase kinase 4 | Homo sapiens (human) | | 0.863 |
Phosphorylase b kinase regulatory subunit alpha, liver isoform | Homo sapiens (human) | | 0.0005 |
Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform | Homo sapiens (human) | | 0.0005 |
Dual specificity mitogen-activated protein kinase kinase 3 | Homo sapiens (human) | | 0.0099 |
Casein kinase I isoform alpha | Homo sapiens (human) | | 3.412 |
Casein kinase I isoform delta | Homo sapiens (human) | | 1.4 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | Homo sapiens (human) | | 9 |
MAP kinase-activated protein kinase 2 | Homo sapiens (human) | | 0.735 |
Cyclin-dependent kinase 8 | Homo sapiens (human) | | 0.0105 |
Casein kinase I isoform epsilon | Homo sapiens (human) | | 1.4 |
Dual specificity protein kinase CLK1 | Homo sapiens (human) | | 0.0108 |
Dual specificity protein kinase CLK2 | Homo sapiens (human) | | 0.6508 |
Dual specificity protein kinase CLK3 | Homo sapiens (human) | | 0.92 |
Glycogen synthase kinase-3 alpha | Homo sapiens (human) | | 0.0103 |
Glycogen synthase kinase-3 beta | Homo sapiens (human) | | 0.0435 |
D(1A) dopamine receptor | Sus scrofa (pig) | | 0.001 |
Cyclin-dependent kinase 7 | Homo sapiens (human) | | 0.2793 |
Cyclin-dependent kinase 9 | Homo sapiens (human) | | 0.0474 |
Tyrosine-protein kinase Blk | Homo sapiens (human) | | 0.0011 |
Interleukin-1 receptor-associated kinase 1 | Homo sapiens (human) | | 0.0377 |
Ribosomal protein S6 kinase alpha-3 | Homo sapiens (human) | | 0.0002 |
Cytoplasmic tyrosine-protein kinase BMX | Homo sapiens (human) | | 0.0046 |
cAMP-dependent protein kinase catalytic subunit PRKX | Homo sapiens (human) | | 0.0014 |
Cyclin-H | Homo sapiens (human) | | 0.2793 |
CDK-activating kinase assembly factor MAT1 | Homo sapiens (human) | | 0.1216 |
Serine/threonine-protein kinase Nek2 | Homo sapiens (human) | | 1.7683 |
Serine/threonine-protein kinase Nek4 | Homo sapiens (human) | | 0.0851 |
Tyrosine-protein kinase JAK3 | Homo sapiens (human) | | 0.0084 |
Dual specificity mitogen-activated protein kinase kinase 6 | Homo sapiens (human) | | 0.0036 |
Serine/threonine-protein kinase PLK1 | Homo sapiens (human) | | 0.4397 |
Death-associated protein kinase 1 | Homo sapiens (human) | | 0.0101 |
LIM domain kinase 1 | Homo sapiens (human) | | 0.0026 |
LIM domain kinase 2 | Homo sapiens (human) | | 0.0956 |
Mitogen-activated protein kinase 12 | Homo sapiens (human) | | 0.4512 |
Mitogen-activated protein kinase 10 | Homo sapiens (human) | | 0.0731 |
5'-AMP-activated protein kinase subunit gamma-1 | Homo sapiens (human) | | 1.1354 |
Ephrin type-B receptor 3 | Homo sapiens (human) | | 1.2855 |
Ephrin type-A receptor 5 | Homo sapiens (human) | | 0.0159 |
Ephrin type-B receptor 4 | Homo sapiens (human) | | 0.1869 |
Ephrin type-B receptor 1 | Homo sapiens (human) | | 0.0694 |
Ephrin type-A receptor 4 | Homo sapiens (human) | | 0.0105 |
Serine/threonine-protein kinase SIK1 | Homo sapiens (human) | | 0.0009 |
Calcium-dependent protein kinase 1 | Plasmodium falciparum K1 | | 0.24 |
Protein kinase C gamma type | Rattus norvegicus (Norway rat) | | 0.2168 |
Casein kinase II subunit beta | Homo sapiens (human) | | 3.4 |
Casein kinase II subunit alpha | Homo sapiens (human) | | 3.4723 |
Protein kinase C beta type | Rattus norvegicus (Norway rat) | | 0.2029 |
SRSF protein kinase 2 | Homo sapiens (human) | | 0.206 |
Casein kinase I isoform gamma-2 | Homo sapiens (human) | | 1.9467 |
Cyclin-A1 | Homo sapiens (human) | | 0.0013 |
Mitogen-activated protein kinase kinase kinase 9 | Homo sapiens (human) | | 0.0044 |
MO15-related protein kinase Pfmrk | Plasmodium falciparum (malaria parasite P. falciparum) | | 4 |
Cyclin-dependent kinase 3 | Homo sapiens (human) | | 0.0118 |
Cyclin-dependent kinase 6 | Homo sapiens (human) | | 0.0395 |
Cyclin-dependent-like kinase 5 | Homo sapiens (human) | | 0.0141 |
Cyclin-dependent kinase 16 | Homo sapiens (human) | | 0.0206 |
Cyclin-dependent kinase 17 | Homo sapiens (human) | | 0.0135 |
Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | | 0.048 |
Protein kinase C epsilon type | Homo sapiens (human) | | 0.0767 |
Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens (human) | | 0.2314 |
Angiopoietin-1 receptor | Homo sapiens (human) | | 0.0823 |
Mitogen-activated protein kinase kinase kinase 10 | Homo sapiens (human) | | 0.1952 |
Protein kinase C theta type | Homo sapiens (human) | | 0.1168 |
Activin receptor type-1 | Homo sapiens (human) | | 1.1354 |
Macrophage-stimulating protein receptor | Homo sapiens (human) | | 0.2195 |
Focal adhesion kinase 1 | Homo sapiens (human) | | 0.078 |
Protein kinase C zeta type | Homo sapiens (human) | | 0.1722 |
Protein kinase C delta type | Homo sapiens (human) | | 0.1283 |
Tyrosine-protein kinase BTK | Homo sapiens (human) | | 0.0288 |
Aldehyde oxidase | Homo sapiens (human) | | 0.0023 |
Tyrosine-protein kinase receptor TYRO3 | Homo sapiens (human) | | 0.0177 |
Cyclin-dependent kinase 18 | Homo sapiens (human) | | 0.0587 |
Activated CDC42 kinase 1 | Homo sapiens (human) | | 0.0299 |
Epithelial discoidin domain-containing receptor 1 | Homo sapiens (human) | | 0.9655 |
Tyrosine-protein kinase ITK/TSK | Homo sapiens (human) | | 0.0068 |
Myotonin-protein kinase | Homo sapiens (human) | | 0.1735 |
Mitogen-activated protein kinase kinase kinase 12 | Homo sapiens (human) | | 0.0992 |
Tyrosine-protein kinase Mer | Homo sapiens (human) | | 0.0331 |
Serine/threonine-protein kinase 4 | Homo sapiens (human) | | 0.0013 |
Serine/threonine-protein kinase PAK 1 | Homo sapiens (human) | | 0.0004 |
Dual specificity mitogen-activated protein kinase kinase 5 | Homo sapiens (human) | | 0.0252 |
Mitogen-activated protein kinase 7 | Homo sapiens (human) | | 4.0032 |
Serine/threonine-protein kinase PAK 2 | Homo sapiens (human) | | 0.0021 |
Serine/threonine-protein kinase 3 | Homo sapiens (human) | | 0.0034 |
Mitogen-activated protein kinase kinase kinase 1 | Homo sapiens (human) | | 0.438 |
cGMP-dependent protein kinase 2 | Homo sapiens (human) | | 0.0161 |
Rho-associated protein kinase 1 | Homo sapiens (human) | | 0.0038 |
Non-receptor tyrosine-protein kinase TNK1 | Homo sapiens (human) | | 0.0012 |
Calcium/calmodulin-dependent protein kinase type II subunit beta | Homo sapiens (human) | | 0.0018 |
Calcium/calmodulin-dependent protein kinase type II subunit gamma | Homo sapiens (human) | | 0.0026 |
Calcium/calmodulin-dependent protein kinase type II subunit delta | Homo sapiens (human) | | 0.0024 |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Homo sapiens (human) | | 0.0095 |
Bone morphogenetic protein receptor type-2 | Homo sapiens (human) | | 1.94 |
Protein-tyrosine kinase 6 | Homo sapiens (human) | | 0.484 |
cGMP-dependent protein kinase 1 | Homo sapiens (human) | | 0.0027 |
Cyclin-dependent kinase 13 | Homo sapiens (human) | | 0.057 |
Calcium/calmodulin-dependent protein kinase type 1 | Homo sapiens (human) | | 0.0032 |
Inhibitor of nuclear factor kappa-B kinase subunit epsilon | Homo sapiens (human) | | 0.0003 |
Protein-tyrosine kinase 2-beta | Homo sapiens (human) | | 0.0095 |
Maternal embryonic leucine zipper kinase | Homo sapiens (human) | | 0.0006 |
Lysine--tRNA ligase | Homo sapiens (human) | | 0.0049 |
Cyclin-dependent kinase 5 activator 1 | Homo sapiens (human) | | 0.0141 |
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial | Homo sapiens (human) | | 0.0005 |
Serine/threonine-protein kinase D1 | Homo sapiens (human) | | 0.1448 |
Serine/threonine-protein kinase 38 | Homo sapiens (human) | | 0.0037 |
Receptor tyrosine-protein kinase erbB-4 | Homo sapiens (human) | | 0.183 |
Ribosomal protein S6 kinase alpha-2 | Homo sapiens (human) | | 0.0002 |
Ephrin type-A receptor 7 | Homo sapiens (human) | | 0.0477 |
Ribosomal protein S6 kinase alpha-1 | Homo sapiens (human) | | 0.0004 |
Dual specificity testis-specific protein kinase 1 | Homo sapiens (human) | | 0.1995 |
Myosin light chain kinase, smooth muscle | Homo sapiens (human) | | 0.0448 |
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 | Homo sapiens (human) | | 0.037 |
Mitogen-activated protein kinase 11 | Homo sapiens (human) | | 1 |
Serine/threonine-protein kinase STK11 | Homo sapiens (human) | | 0.0598 |
Rhodopsin kinase GRK1 | Homo sapiens (human) | | 0.068 |
Coiled-coil domain-containing protein 6 | Homo sapiens (human) | | 0.0022 |
NT-3 growth factor receptor | Homo sapiens (human) | | 0.0002 |
Serine/threonine-protein kinase N1 | Homo sapiens (human) | | 0.0025 |
Serine/threonine-protein kinase N2 | Homo sapiens (human) | | 0.0055 |
Mitogen-activated protein kinase 14 | Homo sapiens (human) | | 0.5052 |
Calcium/calmodulin-dependent protein kinase type IV | Homo sapiens (human) | | 0.1475 |
Mitogen-activated protein kinase kinase kinase 11 | Homo sapiens (human) | | 0.016 |
BDNF/NT-3 growth factors receptor | Homo sapiens (human) | | 0.0004 |
MAP kinase-activated protein kinase 3 | Homo sapiens (human) | | 2.775 |
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | Homo sapiens (human) | | 0.0017 |
Discoidin domain-containing receptor 2 | Homo sapiens (human) | | 0.0008 |
Thioredoxin reductase 1, cytoplasmic | Homo sapiens (human) | | 0.0432 |
Rho-associated protein kinase 2 | Bos taurus (cattle) | | 0.0417 |
Myosin light chain kinase 3 | Homo sapiens (human) | | 0.1585 |
Serine/threonine-protein kinase SBK1 | Homo sapiens (human) | | 0.1464 |
Mitogen-activated protein kinase kinase kinase 19 | Homo sapiens (human) | | 0.0087 |
Leucine-rich repeat serine/threonine-protein kinase 2 | Homo sapiens (human) | | 0.0077 |
Mitogen-activated protein kinase kinase kinase 21 | Homo sapiens (human) | | 1.1175 |
Serine/threonine-protein kinase MRCK alpha | Homo sapiens (human) | | 0.0032 |
Sigma non-opioid intracellular receptor 1 | Cavia porcellus (domestic guinea pig) | | 0.0067 |
Testis-specific serine/threonine-protein kinase 1 | Mus musculus (house mouse) | | 0.0003 |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Rattus norvegicus (Norway rat) | | 0.012 |
Protein kinase C eta type | Rattus norvegicus (Norway rat) | | 0.274 |
Serine/threonine-protein kinase MRCK gamma | Homo sapiens (human) | | 0.0005 |
Calcium/calmodulin-dependent protein kinase type 1B | Homo sapiens (human) | | 0.0044 |
Serine/threonine-protein kinase Nek5 | Homo sapiens (human) | | 0.0864 |
Serine/threonine-protein kinase N3 | Homo sapiens (human) | | 0.0105 |
Serine/threonine-protein kinase ULK3 | Homo sapiens (human) | | 0.0027 |
Kinase suppressor of Ras 2 | Homo sapiens (human) | | 5.4 |
Dual serine/threonine and tyrosine protein kinase | Homo sapiens (human) | | 0.0552 |
Serine/threonine-protein kinase/endoribonuclease IRE2 | Homo sapiens (human) | | 0.0416 |
Serine/threonine-protein kinase MARK2 | Homo sapiens (human) | | 0.0001 |
Serine/threonine-protein kinase TAO1 | Homo sapiens (human) | | 0.0008 |
Serine/threonine-protein kinase Nek8 | Homo sapiens (human) | | 0.0263 |
Serine/threonine-protein kinase tousled-like 2 | Homo sapiens (human) | | 0.0035 |
Serine/threonine-protein kinase 32C | Homo sapiens (human) | | 0.232 |
Serine/threonine-protein kinase pim-3 | Homo sapiens (human) | | 0.0001 |
Myosin light chain kinase family member 4 | Homo sapiens (human) | | 0.0537 |
Homeodomain-interacting protein kinase 1 | Homo sapiens (human) | | 2.639 |
Calcium/calmodulin-dependent protein kinase type 1D | Homo sapiens (human) | | 0.0003 |
Mitogen-activated protein kinase kinase kinase kinase 3 | Homo sapiens (human) | | 0.0001 |
Kinase suppressor of Ras 1 | Homo sapiens (human) | | 6.265 |
Cyclin-dependent kinase-like 3 | Homo sapiens (human) | | 1.1 |
MAP kinase-activated protein kinase 5 | Homo sapiens (human) | | 0.212 |
Serine/threonine-protein kinase BRSK2 | Homo sapiens (human) | | 0.0028 |
Serine/threonine-protein kinase NIM1 | Homo sapiens (human) | | 0.1102 |
Serine/threonine-protein kinase ULK2 | Homo sapiens (human) | | 0.0032 |
Misshapen-like kinase 1 | Homo sapiens (human) | | 0.0004 |
Serine/threonine-protein kinase DCLK2 | Homo sapiens (human) | | 0.089 |
Calcium/calmodulin-dependent protein kinase kinase 1 | Homo sapiens (human) | | 0.0359 |
Casein kinase I isoform alpha-like | Homo sapiens (human) | | 1.84 |
Cyclin-Y | Homo sapiens (human) | | 0.0518 |
Homeodomain-interacting protein kinase 4 | Homo sapiens (human) | | 0.226 |
Myosin-IIIa | Homo sapiens (human) | | 0.0425 |
Serine/threonine-protein kinase Nek11 | Homo sapiens (human) | | 0.521 |
Protein odd-skipped-related 1 | Homo sapiens (human) | | 0.0402 |
Mitogen-activated protein kinase 15 | Homo sapiens (human) | | 0.0081 |
Serine/threonine-protein kinase Nek9 | Homo sapiens (human) | | 0.101 |
Serine/threonine-protein kinase BRSK1 | Homo sapiens (human) | | 0.0007 |
Serine/threonine-protein kinase haspin | Homo sapiens (human) | | 0.0422 |
Rhodopsin kinase GRK7 | Homo sapiens (human) | | 0.0053 |
G2/mitotic-specific cyclin-B3 | Homo sapiens (human) | | 0.0107 |
Myosin-IIIb | Homo sapiens (human) | | 0.0058 |
Dual specificity tyrosine-phosphorylation-regulated kinase 2 | Homo sapiens (human) | | 0.18 |
Phosphorylase b kinase regulatory subunit beta | Homo sapiens (human) | | 0.0005 |
Serine/threonine-protein kinase Sgk3 | Homo sapiens (human) | | 0.073 |
Aurora kinase B | Homo sapiens (human) | | 0.007 |
Lymphokine-activated killer T-cell-originated protein kinase | Homo sapiens (human) | | 0.0691 |
MAP/microtubule affinity-regulating kinase 4 | Homo sapiens (human) | | 0.0001 |
Calcium/calmodulin-dependent protein kinase type 1G | Homo sapiens (human) | | 0.0047 |
Testis-specific serine/threonine-protein kinase 2 | Homo sapiens (human) | | 0.0038 |
Testis-specific serine/threonine-protein kinase 3 | Homo sapiens (human) | | 0.0051 |
Serine/threonine-protein kinase Nek1 | Homo sapiens (human) | | 0.0122 |
PAS domain-containing serine/threonine-protein kinase | Homo sapiens (human) | | 0.0107 |
Calcium/calmodulin-dependent protein kinase kinase 2 | Homo sapiens (human) | | 0.0246 |
SRSF protein kinase 1 | Homo sapiens (human) | | 0.0337 |
Mitogen-activated protein kinase kinase kinase 14 | Homo sapiens (human) | | 2.3 |
Mitogen-activated protein kinase kinase kinase 5 | Homo sapiens (human) | | 0.215 |
Mitogen-activated protein kinase kinase kinase 3 | Homo sapiens (human) | | 0.0092 |
MAP kinase-interacting serine/threonine-protein kinase 1 | Homo sapiens (human) | | 0.0531 |
Testis-specific serine/threonine-protein kinase 6 | Homo sapiens (human) | | 0.1525 |
Serine/threonine-protein kinase 33 | Homo sapiens (human) | | 0.0374 |
Serine/threonine-protein kinase D2 | Homo sapiens (human) | | 0.0014 |
NUAK family SNF1-like kinase 2 | Homo sapiens (human) | | 0.0018 |
Serine/threonine-protein kinase SIK2 | Homo sapiens (human) | | 0.3669 |
Myosin light chain kinase 2, skeletal/cardiac muscle | Homo sapiens (human) | | 0.0147 |
STE20-like serine/threonine-protein kinase | Homo sapiens (human) | | 0.0142 |
Serine/threonine-protein kinase TAO3 | Homo sapiens (human) | | 0.0017 |
Homeodomain-interacting protein kinase 2 | Homo sapiens (human) | | 0.3655 |
Tyrosine-protein kinase Srms | Homo sapiens (human) | | 6.5 |
Homeodomain-interacting protein kinase 3 | Homo sapiens (human) | | 0.456 |
Serine/threonine-protein kinase PLK3 | Homo sapiens (human) | | 0.203 |
Inactive tyrosine-protein kinase PEAK1 | Homo sapiens (human) | | 0.0025 |
Dual specificity protein kinase CLK4 | Homo sapiens (human) | | 0.0723 |
MAP kinase-interacting serine/threonine-protein kinase 2 | Homo sapiens (human) | | 0.0221 |
Serine/threonine-protein kinase Sgk2 | Homo sapiens (human) | | 0.0159 |
Casein kinase I isoform gamma-1 | Homo sapiens (human) | | 5.3367 |
NADPH oxidase 4 | Homo sapiens (human) | | 0.0708 |
Serine/threonine-protein kinase PAK 6 | Homo sapiens (human) | | 0.0327 |
SNF-related serine/threonine-protein kinase | Homo sapiens (human) | | 0.0059 |
Serine/threonine-protein kinase LATS2 | Homo sapiens (human) | | 0.0062 |
Interleukin-1 receptor-associated kinase 4 | Homo sapiens (human) | | 0.0122 |
Serine/threonine-protein kinase 32B | Homo sapiens (human) | | 0.0375 |
Cyclin-dependent kinase 12 | Homo sapiens (human) | | 0.053 |
Serine/threonine-protein kinase PLK2 | Homo sapiens (human) | | 0.546 |
Serine/threonine-protein kinase MARK1 | Homo sapiens (human) | | 0.0003 |
Serine/threonine-protein kinase pim-2 | Homo sapiens (human) | | 0.0813 |
Serine/threonine-protein kinase PAK 5 | Homo sapiens (human) | | 0.0039 |
Serine/threonine-protein kinase 26 | Homo sapiens (human) | | 0.0124 |
Serine/threonine-protein kinase NLK | Homo sapiens (human) | | 0.0666 |
Ribosomal protein S6 kinase beta-2 | Homo sapiens (human) | | 0.0015 |
Protein DBF4 homolog A | Homo sapiens (human) | | 0.0549 |
Serine/threonine-protein kinase 17A | Homo sapiens (human) | | 0.0386 |
STE20/SPS1-related proline-alanine-rich protein kinase | Homo sapiens (human) | | 0.0158 |
Ephrin type-A receptor 6 | Homo sapiens (human) | | 0.0161 |
Serine/threonine-protein kinase TBK1 | Homo sapiens (human) | | 0.003 |
Death-associated protein kinase 2 | Homo sapiens (human) | | 0.0064 |
Ribosomal protein S6 kinase alpha-6 | Homo sapiens (human) | | 0.0001 |
TRAF2 and NCK-interacting protein kinase | Homo sapiens (human) | | 0.0103 |
Serine/threonine-protein kinase tousled-like 1 | Homo sapiens (human) | | 0.0295 |
Serine/threonine-protein kinase TAO2 | Homo sapiens (human) | | 0.0076 |
ALK tyrosine kinase receptor | Homo sapiens (human) | | 0.0044 |
SRSF protein kinase 3 | Homo sapiens (human) | | 1.77 |
Serine/threonine-protein kinase ICK | Homo sapiens (human) | | 0.0443 |
Aurora kinase C | Homo sapiens (human) | | 0.0022 |
Calcium/calmodulin-dependent protein kinase type II subunit alpha | Homo sapiens (human) | | 0.0024 |
Protein kinase C theta type | Rattus norvegicus (Norway rat) | | 0.274 |
RAC-gamma serine/threonine-protein kinase | Homo sapiens (human) | | 0.3701 |
Serine/threonine-protein kinase 38-like | Homo sapiens (human) | | 0.0012 |
Serine/threonine-protein kinase SIK3 | Homo sapiens (human) | | 0.1541 |
Mitogen-activated protein kinase kinase kinase 2 | Homo sapiens (human) | | 0.0335 |
Serine/threonine-protein kinase WNK2 | Homo sapiens (human) | | 1.455 |
Dual specificity tyrosine-phosphorylation-regulated kinase 1B | Homo sapiens (human) | | 0.0017 |
5'-AMP-activated protein kinase subunit beta-1 | Homo sapiens (human) | | 1.1354 |
Mitogen-activated protein kinase kinase kinase kinase 5 | Homo sapiens (human) | | 0.0002 |
Serine/threonine-protein kinase MRCK beta | Homo sapiens (human) | | 0.0027 |
Serine/threonine-protein kinase 24 | Homo sapiens (human) | | 0.0065 |
Casein kinase I isoform gamma-3 | Homo sapiens (human) | | 2.675 |
Chain A, Ribosomal protein S6 kinase alpha-1 | Homo sapiens (human) | | 0.0003 |
Chain X, Tyrosine-protein kinase Lyn | Homo sapiens (human) | | 0.0013 |
Authors | Studies |
García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Bracke, ME; De Ryck, T; Katritzky, AR; Patronov, A; Roman, BI; Slavov, SH; Stevens, CV; Vanhoecke, BW | 1 |
Growdon, JH; Nitsch, RM; Slack, BE; Wurtman, RJ | 1 |
Francis, J; Pon, DJ; Qu, Y; Sen, AK; Torchia, J | 1 |
Bizzarri, C; Corda, D; D'Orazio, MC; Di Girolamo, M | 1 |
Izawa, T; Komabayashi, T; Suda, K; Tsuboi, M; Yakata, A | 1 |
Dehaye, JP; Turner, RJ; Valdez, IH | 1 |
Garg, LC; Mohuczy-Dominiak, D; Saha, PK | 1 |
Farlow, MR; Lahiri, DK | 1 |
Dawson, JJ; Iannazzo, L; Majewski, H | 1 |
Artemenko, IP; Hokin, LE; Los, GV | 1 |
Chung, KT; Lin, CI; Yang, JM | 1 |
Fujimoto, R; Hata, F; Ishii, T; Nishio, H; Saitoh, N; Takeuchi, T | 1 |
Clancy, J; Emala, CW; Hirshman, CA; Schears, G | 1 |
Bouron, A; Reuter, H | 1 |
Eguchi, T; Ishida, H; Ishikawa, Y; Skowronski, MT | 1 |
Costa, LG; Guizzetti, M; Wei, M | 1 |
Cruzblanca, H; Hille, B; Kaftan, EJ; Mackie, K; Roche, JP; Shapiro, MS | 1 |
Miner, AS; Ratz, PH | 1 |
Article | Year |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
4-Fluoro-3',4',5'-trimethoxychalcone as a new anti-invasive agent. From discovery to initial validation in an in vivo metastasis model.European journal of medicinal chemistry, 2015, Aug-28, Volume: 101Topics: Animals; Antineoplastic Agents, Phytogenic; Biological Products; Cell Line, Tumor; Cell Movement; Cell Survival; Chalcones; Chick Embryo; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Discovery; Female; Humans; Mice; Mice, Nude; Molecular Structure; Myocardium; Neoplasm Invasiveness; Neoplasm Metastasis; Quantitative Structure-Activity Relationship | 2015 |
Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors.Science (New York, N.Y.), 1992, Oct-09, Volume: 258, Issue:5080
Topics: Alkaloids; Alzheimer Disease; Amyloid beta-Protein Precursor; Atropine; Blotting, Western; Brain Chemistry; Carbachol; Cell Line; Embryo, Mammalian; Humans; Kidney; Kinetics; Protein Kinase C; Receptors, Muscarinic; Staurosporine; Transfection | 1992 |
Carbachol-stimulated phosphorylation of a 170-kDa endogenous protein in avian salt gland cells.The American journal of physiology, 1991, Volume: 261, Issue:3 Pt 1
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Atropine; Carbachol; Ducks; Ionomycin; Isoquinolines; Kinetics; Molecular Weight; Phosphates; Phosphoproteins; Phosphorylation; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Proteins; Salt Gland; Staurosporine; Tetradecanoylphorbol Acetate | 1991 |
Evidence that a guanine nucleotide-binding protein linked to a muscarinic receptor inhibits directly phospholipase C.Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:12
Topics: Alkaloids; Animals; Atropine; Calcimycin; Calcium; Carbachol; Cell Line; Cell Membrane Permeability; Colforsin; Cyclic AMP; Cytosol; GTP-Binding Proteins; Guanosine Triphosphate; Inositol Phosphates; Kinetics; Norepinephrine; Pertussis Toxin; Phosphatidylinositols; Pirenzepine; Receptors, Muscarinic; Staurosporine; Type C Phospholipases; Virulence Factors, Bordetella | 1990 |
A protein kinase C-dependent mechanism(s) is involved in atropine-resistant accumulation of diacylglycerol in rat parotid gland.Research communications in chemical pathology and pharmacology, 1990, Volume: 70, Issue:1
Topics: Alkaloids; Animals; Atropine; Carbachol; Diglycerides; Dose-Response Relationship, Drug; Male; Parotid Gland; Phosphatidylinositol Phosphates; Phosphatidylinositols; Protein Kinase C; Rats; Rats, Inbred Strains; Staurosporine; Time Factors | 1990 |
Beta-adrenergic stimulation and cAMP mobilize Ca2+ from an IP3-insensitive pool in rat submandibular granular ducts.The American journal of physiology, 1993, Volume: 265, Issue:5 Pt 1
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Adrenergic beta-Antagonists; Alkaloids; Animals; Atenolol; Atropine; Calcium; Carbachol; Cyclic AMP; Epinephrine; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Isoproterenol; Isoquinolines; Kinetics; Male; Phentolamine; Piperazines; Propanolamines; Propranolol; Protein Kinase C; Protein Kinase Inhibitors; Putrescine; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Staurosporine; Submandibular Gland | 1993 |
Cholinergic inhibition of Na-K-ATPase via activation of protein kinase C in Madin-Darby canine kidney cells.Journal of the American Society of Nephrology : JASN, 1993, Volume: 4, Issue:2
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Atropine; Carbachol; Cells, Cultured; Dogs; Enzyme Activation; Epithelium; Inositol Phosphates; Isoquinolines; Kidney; Naphthalenes; Parasympathomimetics; Phorbol Esters; Piperazines; Protein Kinase C; Receptors, Muscarinic; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Staurosporine; Sulfonamides | 1993 |
Differential effect of tacrine and physostigmine on the secretion of the beta-amyloid precursor protein in cell lines.Journal of molecular neuroscience : MN, 1996,Spring, Volume: 7, Issue:1
Topics: Amyloid beta-Protein Precursor; Animals; Arecoline; Astrocytes; Atropine; Calcimycin; Carbachol; Cholinesterase Inhibitors; Enzyme Inhibitors; HeLa Cells; Humans; Ionophores; Muscarinic Agonists; Muscarinic Antagonists; Neuroblastoma; PC12 Cells; Physostigmine; Rats; Staurosporine; Tacrine | 1996 |
Muscarinic autoinhibition of acetylcholine release in mouse atria is not transduced through cyclic AMP or protein kinase C.Journal of autonomic pharmacology, 1996, Volume: 16, Issue:2
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Adenylyl Cyclases; Animals; Atrial Function; Atropine; Colforsin; Cyclic AMP; Enzyme Activation; Enzyme Inhibitors; Heart; Heart Atria; In Vitro Techniques; Male; Mice; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Muscarinic; Second Messenger Systems; Staurosporine | 1996 |
Phosphoinositide signalling in human neuroblastoma cells: biphasic effect of Li+ on the level of the inositolphosphate second messengers.Advances in enzyme regulation, 1996, Volume: 36Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Atropine; Calcium; Egtazic Acid; Enzyme Inhibitors; Humans; Indoles; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Lithium; Maleimides; Neuroblastoma; Nickel; Phosphatidylinositols; Protein Kinase Inhibitors; Signal Transduction; Staurosporine; Tumor Cells, Cultured | 1996 |
Simultaneous effects of carbachol on intracellular Na+ activity, action potential, and twitch tension in guinea-pig cardiac ventricular papillary muscles.The Japanese journal of physiology, 1996, Volume: 46, Issue:3
Topics: Action Potentials; Animals; Atropine; Carbachol; Cesium; Enzyme Inhibitors; Guinea Pigs; Heart Ventricles; Intracellular Membranes; Male; Muscarinic Agonists; Myocardial Contraction; Papillary Muscles; Sodium; Staurosporine | 1996 |
Muscarinic autoinhibition and modulatory role of protein kinase C in acetylcholine release from the myenteric plexus of guinea pig ileum.Japanese journal of pharmacology, 1997, Volume: 74, Issue:2
Topics: Acetylcholine; Animals; Arachidonic Acid; Atropine; Benzoquinones; Chromatography, High Pressure Liquid; Electric Stimulation; Estrenes; Guinea Pigs; Ileum; In Vitro Techniques; Lipoxygenase Inhibitors; Male; Melitten; Muscle, Smooth; Myenteric Plexus; Naphthalenes; Phorbol 12,13-Dibutyrate; Phospholipases A; Phospholipases A2; Protein Kinase C; Pyrrolidinones; Quinacrine; Receptors, Muscarinic; Staurosporine; Type C Phospholipases | 1997 |
Chronic carbachol pretreatment decreases adenylyl cyclase activity in airway smooth muscle.The American journal of physiology, 1997, Volume: 273, Issue:3 Pt 1
Topics: Adenylyl Cyclases; Animals; Atropine; Carbachol; Cattle; Guanosine Triphosphate; In Vitro Techniques; Isoproterenol; Kinetics; Muscle, Smooth; Protein Kinase C; Receptor, Muscarinic M3; Receptors, Muscarinic; Staurosporine; Trachea | 1997 |
Muscarinic stimulation of synaptic activity by protein kinase C is inhibited by adenosine in cultured hippocampal neurons.Proceedings of the National Academy of Sciences of the United States of America, 1997, Oct-28, Volume: 94, Issue:22
Topics: Adenosine; Animals; Animals, Newborn; Atropine; Calcium; Carbachol; Cells, Cultured; Dose-Response Relationship, Drug; Electric Conductivity; Enzyme Activation; Excitatory Postsynaptic Potentials; Hippocampus; Muscarinic Agonists; Muscarinic Antagonists; Neurons; Nicotinic Antagonists; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Muscarinic; Staurosporine; Synapses; Synaptic Transmission | 1997 |
Acetylcholine acts on M3 muscarinic receptors and induces the translocation of aquaporin5 water channel via cytosolic Ca2+ elevation in rat parotid glands.Biochemical and biophysical research communications, 1998, Apr-28, Volume: 245, Issue:3
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Animals; Aquaporin 5; Aquaporins; Atropine; Calcimycin; Calcium; Calcium Channel Blockers; Cytosol; Diamines; Enzyme Inhibitors; Gallic Acid; Ion Channels; Ionophores; Male; Membrane Proteins; Parasympatholytics; Parotid Gland; Rats; Rats, Wistar; Receptor, Muscarinic M3; Receptors, Muscarinic; Staurosporine | 1998 |
The role of protein kinase C alpha and epsilon isozymes in DNA synthesis induced by muscarinic receptors in a glial cell line.European journal of pharmacology, 1998, Oct-23, Volume: 359, Issue:2-3
Topics: Astrocytoma; Atropine; Carbachol; Carcinogens; DNA; Dose-Response Relationship, Drug; Down-Regulation; Drug Synergism; Enzyme Inhibitors; Humans; Indoles; Isoenzymes; Maleimides; Muscarinic Agonists; Muscarinic Antagonists; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; Radioligand Assay; Receptors, Muscarinic; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1998 |
Reconstitution of muscarinic modulation of the KCNQ2/KCNQ3 K(+) channels that underlie the neuronal M current.The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, Mar-01, Volume: 20, Issue:5
Topics: Animals; Anthracenes; Atropine; Calcium; Calcium Signaling; Cells, Cultured; Chelating Agents; Cloning, Molecular; Cytoplasm; Egtazic Acid; Enzyme Inhibitors; Ethylmaleimide; Gene Expression; GTP-Binding Proteins; Humans; KCNQ2 Potassium Channel; KCNQ3 Potassium Channel; Male; Muscarinic Agonists; Muscarinic Antagonists; Neurons; Oxotremorine; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Voltage-Gated; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Second Messenger Systems; Staurosporine; Superior Cervical Ganglion; Tetraethylammonium; Thapsigargin | 2000 |
Length-dependent regulation of basal myosin phosphorylation and force in detrusor smooth muscle.American journal of physiology. Regulatory, integrative and comparative physiology, 2003, Volume: 284, Issue:4
Topics: Animals; Atropine; Calcium; Enzyme Inhibitors; Female; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Muscle Contraction; Muscle Tonus; Muscle, Smooth; Myosin Light Chains; Phosphorylation; Protein Serine-Threonine Kinases; Rabbits; rho-Associated Kinases; Staurosporine; Time Factors; Urinary Bladder | 2003 |