atropine has been researched along with sk&f-38393 in 15 studies
| Studies (atropine) | Trials (atropine) | Recent Studies (post-2010) (atropine) | Studies (sk&f-38393) | Trials (sk&f-38393) | Recent Studies (post-2010) (sk&f-38393) |
|---|---|---|---|---|---|
| 26,711 | 1,259 | 1,697 | 2,012 | 29 | 242 |
| 26,711 | 1,259 | 1,697 | 20 | 0 | 3 |
| Protein | Taxonomy | atropine (IC50) | sk&f-38393 (IC50) |
|---|---|---|---|
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | 2.8 | |
| D | Rattus norvegicus (Norway rat) | 0.19 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 3.75 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (13.33) | 18.7374 |
| 1990's | 10 (66.67) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amsler, CD; Baker, BJ; Hahn, KN; Kyle, DE; Lebar, MD; Maignan, P; McClintock, JB; Mutka, T; van Olphen, A | 1 |
| Dotman, CH; Mulder, AH; Schoffelmeer, AN; Van Vliet, BJ; Wardeh, G | 1 |
| Gretler, DD; Jones, KC; Murphy, MB | 1 |
| Carino, MA; Horita, A | 1 |
| Carino, MA; Horita, A; Nishimura, Y | 1 |
| Boggan, WO; Faught, K; Middaugh, LD | 1 |
| Poursoltan, M; Zarrindast, MR | 1 |
| Broekkamp, CL; Collins, P; Jenner, P; Marsden, CD | 1 |
| Bronstein, DM; Hong, JS; Hudson, PM; Pennypacker, KR; Ye, H | 1 |
| Dorsa, DM; Merchant, KM | 1 |
| Friedman, E; Undie, AS | 1 |
| Carlen, PL; Han, D; Velazquez, JL | 1 |
| Gomita, Y; Nakagawa, T; Ohyama, T; Okamura, H; Ukai, K | 1 |
| Chen, CF; Chou, YC; Liao, JF; Wang, HH | 1 |
| Booth, RG; Brown, RL; Bucholtz, EC; Tropsha, A; Wyrick, SD | 1 |
15 other study(ies) available for atropine and sk&f-38393
| Article | Year |
|---|---|
CNS and antimalarial activity of synthetic meridianin and psammopemmin analogs.
Topics: Antimalarials; Cell Line, Tumor; Central Nervous System Agents; Humans; Indole Alkaloids; Indoles; Plasmodium falciparum; Pyrimidines; Receptors, Serotonin | 2011 |
Differential effects of chronic agonist administration on mu-opioid receptor- and muscarinic receptor-regulated adenylate cyclase in rat striatal neurons.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenylyl Cyclases; Animals; Atropine; Cells, Cultured; Corpus Striatum; Morphine; Oxotremorine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Muscarinic; Receptors, Opioid; Receptors, Opioid, mu; Up-Regulation | 1992 |
5-Hydroxytryptamine receptor activity of the dopamine receptor agonist fenoldopam in canine tracheal smooth muscle.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Acetylcholine; Animals; Atropine; Benzazepines; Dogs; Dopamine Agents; Drug Interactions; Fenoldopam; In Vitro Techniques; Indomethacin; Ketanserin; Methysergide; Muscle, Smooth; Receptors, Serotonin; Serotonin; Trachea; Vasodilator Agents | 1992 |
D-1 agonist, SKF 38393, but not a D-2 agonist, produces a cholinergically mediated analeptic effect in rabbits.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Atropine; Atropine Derivatives; Behavior, Animal; Central Nervous System Stimulants; Dopamine Agents; Dopamine Antagonists; Ergolines; Male; Oxotremorine; Parasympathetic Nervous System; Pentobarbital; Physostigmine; Quinpirole; Rabbits; Raclopride; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Salicylamides | 1991 |
D1 agonist SKF 38393 antagonizes pentobarbital-induced narcosis and depression of hippocampal and cortical cholinergic activity in rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Anesthesia; Animals; Atropine; Atropine Derivatives; Cerebral Cortex; Choline; Ergolines; Hippocampus; Male; Pentobarbital; Quinpirole; Rats; Rats, Inbred Strains | 1991 |
Effect of dopaminergic drugs on enhancement of the binding of quinuclidinyl benzilate by phencyclidine in vivo.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Atropine; Benzazepines; Dopamine; Dopamine Agents; Ergolines; Hydroxydopamines; Male; Mice; Mice, Inbred C57BL; Norepinephrine; Oxidopamine; Phencyclidine; Quinpirole; Quinuclidines; Quinuclidinyl Benzilate | 1989 |
Interactions of drugs acting on central dopamine receptors and cholinoceptors on yawning responses in the rat induced by apomorphine, bromocriptine or physostigmine.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Atropine; Behavior, Animal; Benzazepines; Bromocriptine; Drug Interactions; Male; Physostigmine; Rats; Receptors, Cholinergic; Receptors, Dopamine; Theophylline; Yawning | 1989 |
Electromyographical differentiation of the components of perioral movements induced by SKF 38393 and physostigmine in the rat.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Atropine; Benzazepines; Cholinergic Agonists; Dose-Response Relationship, Drug; Electromyography; Male; Mouth; Movement; Physostigmine; Rats; Rats, Wistar; Receptors, Dopamine D1; Stereotyped Behavior; Tremor; Yawning | 1993 |
Role of a 35 kDa fos-related antigen (FRA) in the long-term induction of striatal dynorphin expression in the 6-hydroxydopamine lesioned rat.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Atropine; Base Sequence; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dynorphins; Ergolines; Gene Expression Regulation; Genes, fos; Genes, Immediate-Early; Genes, jun; Immediate-Early Proteins; Male; Molecular Sequence Data; Nerve Tissue Proteins; Oxidopamine; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Quinpirole; Rats; Rats, Inbred F344; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate; RNA, Messenger | 1994 |
Differential induction of neurotensin and c-fos gene expression by typical versus atypical antipsychotics.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antipsychotic Agents; Atropine; Benzazepines; Corpus Striatum; Ergolines; Gene Expression; Genes; Genes, fos; Haloperidol; In Situ Hybridization; Male; Neurons; Neurotensin; Nucleus Accumbens; Peptide Fragments; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; RNA, Messenger | 1993 |
Diet restriction prevents aging-induced deficits in brain phosphoinositide metabolism.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aging; Animals; Atropine; Brain; Carbachol; Chlorides; Energy Intake; Frontal Lobe; Inositol Phosphates; Lithium; Lithium Chloride; Male; Phosphatidylinositols; Rats; Rats, Inbred F344; Second Messenger Systems; Tritium; Visual Cortex | 1993 |
Neurotransmitter modulation of gap junctional communication in the rat hippocampus.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Atropine; Benzazepines; Carbachol; Cell Communication; Cholinergic Fibers; Dopamine Agonists; Dopamine Antagonists; Fluorescent Dyes; Gap Junctions; Hippocampus; Isoquinolines; Neurons; Neurotransmitter Agents; Parasympatholytics; Parasympathomimetics; Rats; Rats, Wistar; Receptors, Dopamine D1 | 1997 |
Effect of dopaminergic drugs on the reserpine-induced lowering of hippocampal theta wave frequency in rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antipsychotic Agents; Atropine; Bupropion; Cyclobutanes; Desipramine; Dopamine Agents; Dopamine Agonists; Hippocampus; Male; Methamphetamine; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine; Reserpine; Theta Rhythm | 2000 |
Dimemorfan enhances acetylcholine release from rat hippocampal slices.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Acetylcholine; Animals; Antipsychotic Agents; Atropine; Carbachol; Cholinergic Agonists; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Hippocampus; In Vitro Techniques; Male; Morphinans; Muscarinic Antagonists; Phenazocine; Potassium Chloride; Rats; Tritium | 2004 |
Synthesis, evaluation, and comparative molecular field analysis of 1-phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes as ligands for histamine H(1) receptors.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ligands; Models, Molecular; Pyrilamine; Radioligand Assay; Structure-Activity Relationship; Tetrahydronaphthalenes | 1999 |