Page last updated: 2024-09-05

atropine and sibutramine

atropine has been researched along with sibutramine in 5 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(sibutramine)
Trials
(sibutramine)
Recent Studies (post-2010) (sibutramine)
26,7111,2591,697967218204

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)sibutramine (IC50)
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)5.665
Alpha-2B adrenergic receptorHomo sapiens (human)2.39
Sodium-dependent noradrenaline transporter Homo sapiens (human)5.665
Sodium-dependent serotonin transporterHomo sapiens (human)2.085
Sodium-dependent dopamine transporter Homo sapiens (human)0.632

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Aronne, LJ; Hirsch, J; Mackintosh, RM1
Gomita, Y; Nakagawa, T; Ohyama, T; Okamura, H; Ukai, K1

Reviews

1 review(s) available for atropine and sibutramine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for atropine and sibutramine

ArticleYear
The effects of drugs used to treat obesity on the autonomic nervous system.
    Obesity research, 2000, Volume: 8, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Appetite Depressants; Atropine; Autonomic Nervous System; Basal Metabolism; Calorimetry; Creatinine; Cyclobutanes; Dexfenfluramine; Dopamine; Epinephrine; Heart Rate; Humans; Male; Norepinephrine; Obesity; Parasympatholytics; Phentermine; Propanolamines; Serotonin Receptor Agonists; Single-Blind Method

2000

Other Studies

3 other study(ies) available for atropine and sibutramine

ArticleYear
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Effect of dopaminergic drugs on the reserpine-induced lowering of hippocampal theta wave frequency in rats.
    Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 2000, Volume: 20, Issue:2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antipsychotic Agents; Atropine; Bupropion; Cyclobutanes; Desipramine; Dopamine Agents; Dopamine Agonists; Hippocampus; Male; Methamphetamine; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine; Reserpine; Theta Rhythm

2000