Page last updated: 2024-09-05

atropine and sb 223412

atropine has been researched along with sb 223412 in 2 studies

Compound Research Comparison

Studies (atropine)	Trials (atropine)	Recent Studies (post-2010) (atropine)	Studies (sb 223412)	Trials (sb 223412)	Recent Studies (post-2010) (sb 223412)
26,711	1,259	1,697	49	2	16

Protein Interaction Comparison

Protein	Taxonomy	sb 223412 (IC50)
Bile salt export pump	Homo sapiens (human)	10
Cytochrome P450 1A2	Homo sapiens (human)	5
Cytochrome P450 3A4	Homo sapiens (human)	4
Cytochrome P450 2C9	Homo sapiens (human)	2
Neuromedin-K receptor	Homo sapiens (human)	0.0084
Cytochrome P450 2C19	Homo sapiens (human)	9

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Bornstein, JC; Larsson, MH; Lindström, E; Sapnara, M; Sjövall, H; Svensson, DJ; Thomas, EA	1

Other Studies

2 other study(ies) available for atropine and sb 223412

Article	Year
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Pharmacological analysis of components of the change in transmural potential difference evoked by distension of rat proximal small intestine in vivo. American journal of physiology. Gastrointestinal and liver physiology, 2008, Volume: 294, Issue:1 Topics: Anesthetics, Local; Animals; Atropine; Chlorides; Colon; Duodenum; Enzyme Inhibitors; Ganglionic Blockers; Granisetron; Hexamethonium; Hormone Antagonists; Injections, Intravenous; Intestinal Secretions; Lidocaine; Male; Mechanotransduction, Cellular; Membrane Potentials; Mice; Mice, Inbred C57BL; Muscarinic Antagonists; Neurokinin-1 Receptor Antagonists; Nitric Oxide Synthase; Nitroarginine; Peripheral Nervous System Agents; Piperidines; Pressure; Quinolines; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Receptors, Serotonin, 5-HT3; Receptors, Vasoactive Intestinal Peptide; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists; Tetrodotoxin; Time Factors; Vasoactive Intestinal Peptide	2008

Article

Year

Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.

Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012

Pharmacological analysis of components of the change in transmural potential difference evoked by distension of rat proximal small intestine in vivo.

American journal of physiology. Gastrointestinal and liver physiology, 2008, Volume: 294, Issue:1

Topics: Anesthetics, Local; Animals; Atropine; Chlorides; Colon; Duodenum; Enzyme Inhibitors; Ganglionic Blockers; Granisetron; Hexamethonium; Hormone Antagonists; Injections, Intravenous; Intestinal Secretions; Lidocaine; Male; Mechanotransduction, Cellular; Membrane Potentials; Mice; Mice, Inbred C57BL; Muscarinic Antagonists; Neurokinin-1 Receptor Antagonists; Nitric Oxide Synthase; Nitroarginine; Peripheral Nervous System Agents; Piperidines; Pressure; Quinolines; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Receptors, Serotonin, 5-HT3; Receptors, Vasoactive Intestinal Peptide; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists; Tetrodotoxin; Time Factors; Vasoactive Intestinal Peptide

2008