Compounds > atropine
Page last updated: 2024-09-05

atropine and rolipram

atropine has been researched along with rolipram in 7 studies

Compound Research Comparison

Studies
(atropine)		Trials
(atropine)		Recent Studies (post-2010)
(atropine)		Studies
(rolipram)		Trials
(rolipram)		Recent Studies (post-2010) (rolipram)
26,7111,2591,6971,60417401

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)rolipram (IC50)
cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)1.2233
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8AHomo sapiens (human)1.2233
Retina-specific copper amine oxidaseHomo sapiens (human)0.0003
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)1.0975
3',5'-cyclic-AMP phosphodiesterase Sus scrofa (pig)3.63
ReninHomo sapiens (human)3.5
Tumor necrosis factorHomo sapiens (human)0.35
cAMP-specific 3',5'-cyclic phosphodiesterase 4D Rattus norvegicus (Norway rat)0.7287
cAMP-specific 3',5'-cyclic phosphodiesterase 4CRattus norvegicus (Norway rat)0.7287
cAMP-specific 3',5'-cyclic phosphodiesterase 4BRattus norvegicus (Norway rat)0.8447
cAMP-specific 3',5'-cyclic phosphodiesterase 4AHomo sapiens (human)1.1942
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)0.095
Delta-type opioid receptorMus musculus (house mouse)1.5
Delta-type opioid receptorRattus norvegicus (Norway rat)1.5
cAMP-specific 3',5'-cyclic phosphodiesterase 4ARattus norvegicus (Norway rat)0.7287
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BHomo sapiens (human)0.835
cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)1.1005
cAMP-specific 3',5'-cyclic phosphodiesterase 4CHomo sapiens (human)1.61
cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)1.0794
cGMP-inhibited 3',5'-cyclic phosphodiesterase BHomo sapiens (human)0.835
cGMP-inhibited 3',5'-cyclic phosphodiesterase AHomo sapiens (human)2
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11AHomo sapiens (human)0.835
cAMP-specific 3',5'-cyclic phosphodiesterase 7BHomo sapiens (human)0.835
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10AHomo sapiens (human)0.835

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's2 (28.57)18.2507
2000's1 (14.29)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Gustafsson, LE1
Conanan, ND; Ellis, JL1
Ellis, JL; Fernandes, LB; Undem, BJ1
Alfonzo, MJ; González de Alfonzo, R; Guerra de González, L; Lippo de Bécemberg, I1
Gilani, AH; Shah, AJ1

Other Studies

7 other study(ies) available for atropine and rolipram

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Adenosine antagonism and related effects of theophylline derivatives in guinea pig ileum longitudinal muscle.
    Acta physiologica Scandinavica, 1984, Volume: 122, Issue:2

    Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Animals; Atropine; Choline; Electric Stimulation; Guinea Pigs; Ileum; Male; Muscle Contraction; Muscle, Smooth; Pyrrolidinones; Rolipram; Synaptic Transmission; Tetrodotoxin; Theophylline

1984
Modulation of relaxant responses evoked by a nitric oxide donor and by nonadrenergic, noncholinergic stimulation by isozyme-selective phosphodiesterase inhibitors in guinea pig trachea.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 272, Issue:3

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Atropine; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Electric Stimulation; Guanidines; Guinea Pigs; Indomethacin; Isoenzymes; Muscle Relaxation; Nitric Oxide; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Propranolol; Purinones; Pyridazines; Pyrrolidinones; Receptors, Adrenergic; Receptors, Cholinergic; Rolipram; Trachea; Vasoactive Intestinal Peptide; Xanthines

1995
Potentiation of nonadrenergic noncholinergic relaxation of human isolated bronchus by selective inhibitors of phosphodiesterase isozymes.
    American journal of respiratory and critical care medicine, 1994, Volume: 150, Issue:5 Pt 1

    Topics: Atropine; Bronchi; Colforsin; Electric Stimulation; Histamine; Humans; In Vitro Techniques; Indomethacin; Isoenzymes; Molsidomine; Muscle Relaxation; Nitroprusside; Phosphodiesterase Inhibitors; Propranolol; Purinones; Pyrrolidinones; Rolipram

1994
Cyclic nucleotide-dependent phosphodiesterases (PDEI) inhibition by muscarinic antagonists in bovine tracheal smooth muscle.
    Biochemical pharmacology, 2004, Aug-15, Volume: 68, Issue:4

    Topics: Animals; Atropine; Cattle; Cell-Free System; Cyclic AMP; Cyclic GMP; Muscarinic Antagonists; Muscle, Smooth; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Purinones; Rolipram; Trachea; Vinca Alkaloids

2004
Bronchodilatory effect of Acorus calamus (Linn.) is mediated through multiple pathways.
    Journal of ethnopharmacology, 2010, Sep-15, Volume: 131, Issue:2

    Topics: Acorus; Animals; Atropine; Bronchodilator Agents; Calcium Channel Blockers; Carbachol; Female; Guinea Pigs; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth; Papaverine; Phosphodiesterase 4 Inhibitors; Plant Extracts; Potassium; Rhizome; Rolipram; Trachea; Verapamil

2010