Compounds > atropine
Page last updated: 2024-09-05

atropine and ro 31-8220

atropine has been researched along with ro 31-8220 in 3 studies

Compound Research Comparison

Studies
(atropine)		Trials
(atropine)		Recent Studies (post-2010)
(atropine)		Studies
(ro 31-8220)		Trials
(ro 31-8220)		Recent Studies (post-2010) (ro 31-8220)
26,7111,2591,697587164

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)ro 31-8220 (IC50)
Ribosomal protein S6 kinase alpha-5Homo sapiens (human)0.008
Serine/threonine-protein kinase 10Homo sapiens (human)0.099
cAMP-dependent protein kinase catalytic subunit alphaBos taurus (cattle)0.9
Serine/threonine-protein kinase pim-1Homo sapiens (human)0.01
Protein kinase C alpha typeHomo sapiens (human)0.033
Glycogen synthase kinase-3 betaRattus norvegicus (Norway rat)0.0068
Ribosomal protein S6 kinase beta-1Homo sapiens (human)0.015
Mitogen-activated protein kinase kinase kinase 8Homo sapiens (human)9.95
Glycogen synthase kinase-3 betaHomo sapiens (human)0.0116
Ribosomal protein S6 kinase alpha-3Homo sapiens (human)0.01
Protein kinase C beta typeRattus norvegicus (Norway rat)0.01
Homeodomain-interacting protein kinase 1Homo sapiens (human)0.621
NAD-dependent protein deacetylase sirtuin-2Homo sapiens (human)0.875
Mitogen-activated protein kinase kinase kinase kinase 1Homo sapiens (human)0.0529
NAD-dependent protein deacetylase sirtuin-1Homo sapiens (human)3.9
Serine/threonine-protein kinase VRK1Homo sapiens (human)0.743
NAD-dependent protein deacetylase sirtuin-3, mitochondrialHomo sapiens (human)3.7
Serine/threonine-protein kinase TBK1Homo sapiens (human)0.656

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
McCall, R; McGrath, JC; Nally, JE; Thomson, NC; Wakelam, MJ; Young, LC1
Harbon, S; Lajat, S; Tanfin, Z1
Fukui, H; Horio, S; Izumi, N; Kawakami, N; Miyoshi, K; Wakayama, Y1

Other Studies

3 other study(ies) available for atropine and ro 31-8220

ArticleYear
Mechanical and biochemical responses to endothelin-1 and endothelin-3 in human bronchi.
    European journal of pharmacology, 1994, Dec-15, Volume: 288, Issue:1

    Topics: Atropine; Bronchi; Calcium; Dose-Response Relationship, Drug; Endothelins; Glycopeptides; Humans; In Vitro Techniques; Indoles; Indomethacin; Inositol 1,4,5-Trisphosphate; Muscle Contraction; Muscle, Smooth; Nifedipine; Phorbol 12,13-Dibutyrate; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Protease Inhibitors; Protein Kinase C

1994
Carbachol-induced desensitization of PLC-beta pathway in rat myometrium: downregulation of Gqalpha/G11alpha.
    The American journal of physiology, 1998, Volume: 275, Issue:3

    Topics: Aluminum Compounds; Animals; Atropine; Carbachol; Enzyme Inhibitors; Female; Fluorides; GTP-Binding Proteins; In Vitro Techniques; Indoles; Inositol; Inositol Phosphates; Isoenzymes; Kinetics; Membrane Potentials; Myometrium; N-Methylscopolamine; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Phospholipase C beta; Radioligand Assay; Rats; Rats, Wistar; Receptors, Muscarinic; Signal Transduction; Type C Phospholipases

1998
Histamine H1 receptor down-regulation mediated by M3 muscarinic acetylcholine receptor subtype.
    Journal of pharmacological sciences, 2004, Volume: 95, Issue:4

    Topics: Animals; Atropine; Carbachol; Carbazoles; CHO Cells; Cholinergic Agonists; Cricetinae; Cricetulus; Down-Regulation; Histamine H1 Antagonists; Indoles; Inositol Phosphates; Muscarinic Antagonists; Phosphorylation; Protein Kinase C; Pyrilamine; Radioligand Assay; Receptor, Muscarinic M3; Receptors, Histamine H1; Signal Transduction; Time Factors

2004