Page last updated: 2024-09-05

atropine and ranitidine

atropine has been researched along with ranitidine in 68 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(ranitidine)
Trials
(ranitidine)
Recent Studies (post-2010) (ranitidine)
26,7111,2591,69785029
26,7111,2591,6975,2981,788445

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)ranitidine (IC50)
Potassium-transporting ATPase alpha chain 1Homo sapiens (human)0.04
AcetylcholinesteraseHomo sapiens (human)1.475
Potassium-transporting ATPase subunit betaHomo sapiens (human)0.04
Multidrug and toxin extrusion protein 1Homo sapiens (human)8.3

Research

Studies (68)

TimeframeStudies, this research(%)All Research%
pre-199017 (25.00)18.7374
1990's17 (25.00)18.2507
2000's21 (30.88)29.6817
2010's13 (19.12)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chapman, JM; Kosh, JW; Sowell, JW; Tang, Y; Usher, LA; Valli, MJ; Vaughan, CM1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Alimuddin, M; Bulloch, D; Dahl, R; Grant, D; Lee, N; Peacock, M1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Ahman, M; Holmén, AG; Wan, H1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Fung, L; Greenberg, GR; Pokol-Daniel, S1
Estañ, L; Martínez-Mir, MI; Morales-Olivas, FJ; Rubio, E1
Hirshman, CA; Lindeman, KS; Mehr, EH1
Feldman, M; Lin, HJ; McArthur, KE; Prince, MD; Redfern, JS1
Harding, M; Hayward, NJ; Hughes, J; Lloyd, SA; McKnight, AT; Woodruff, GN1
Batzri, S; Brugada, O; Harmon, JW; Rich, NM1
Gledhill, T; Hunt, RH1
Ewen, A; Koehli, N; Maltby, JR; Shaffer, EA1
Del Soldato, P2
Bilski, J; Cieszkowski, M; Konturek, SJ; Tasler, J; Thor, P1
Allegri, G; Dobrilla, G; Pellegrini, K1
Kinni, ME; Stout, MM1
Elezoglou, V; Kounenis, G; Koutsoviti-Papadopoulou, M1
Cohen, S; Nissenkorn, I; Rubinstein, R1
Brock-Utne, JG; Downing, JW; Humphrey, D1
Bueno, L; Fioramonti, J; Honde, C; Soldani, G1
Daniotti, S; Del Soldato, P; Foschi, D; Varin, L1
Bohman, T; Larssen, S; Myren, J; Osnes, M1
Cingolani, ML; Concettoni, C; Re, L; Rossini, L1
Del Tacca, M; Ruckebusch, Y; Soldani, G1
Danilewitz, M; Hirschowitz, BI; Molina, E1
Beil, W; Bersimbaev, RI; Gandjour, A; Heim, HK; Sewing, KF1
Furusawa, A; Kaneko, H; Maeda, Y; Mitsuma, T; Morise, K; Nagai, H; Nakada, K; Uchida, K1
Hiyoshi, Y; Iguchi, A; Li, X; Nonogaki, K; Ozawa, K; Sakamoto, N; Tamagawa, T; Watanabe, G1
Iguchi, A; Kunoh, Y; Nonogaki, K; Sakamoto, N; Tamagawa, T; Zhu, LX1
Ferrara, JJ; Flint, LM; Force, SD; Franklin, EW; Hyman, AL; Lippton, HL; Taheri, PA1
Copius Peereboom-Stegeman, JH; Russel, FG; Van der Aa, EM; Wouterse, AC1
Harada, K; Kohgo, Y; Okumura, T; Watanabe, Y1
Buljat, G; Gjurasin, M; Grabarević, Z; Hanzevacki, M; Jadrijević, S; Jagić, V; Jelovac, N; Jurina, L; Konjevoda, P; Marović, A; Miklić, P; Mikus, D; Mise, S; Perić, J; Perović, D; Petek, M; Rotkvić, I; Rucman, R; Seiwerth, S; Separović, J; Sikirić, P; Turković, B; Zoricić, I1
Bruyneel, P; Cornil, P; De Smet, MC; Schrijvers, D; Tai-Apin, C; Vermorken, JB1
Aralica, G; Desković, S; Grabarević, Z; Jadrijević, S; Konjevoda, P; Marović, A; Perović, D; Petek, M; Rucman, R; Seiwerth, S; Sikirić, P; Sosa, T; Turković, B1
Adame, M; Calderón, R; Fernández-Liesa, JI; Mendieta, JM; Muñoz, C; Panadero, A1
Ishikawa, K; Kitamura, H; Kumagai, K; Kuno, N; Nishiwaki, K; Okamoto, S; Sato, K; Shimada, Y; Yano, K1
Kucheriavykh, LE; Nozdrachev, AD; Skopichev, VG1
Anic, T; Aralica, G; Bilic, I; Buljat, G; Ivankovic, D; Mikus, D; Mise, S; Perovic, D; Petek, M; Prkacin, I; Rotkvic, I; Rucman, R; Seiwerth, S; Separovic, J; Sikiric, P; Stancic-Rokotov, D; Zoricic, I1
Al Obaid, AR; Al Rasheed, NM; Al Sayed, MI; Al Zuhair, HH; Fatani, AJ1
Anic, T; Batelja, L; Bedekovic, V; Boban Blagaic, A; Drvis, P; Gjurasin, M; Kalogjera, L; Kopljar, M; Mise, S; Seiwerth, S; Sikiric, P; Staresinic, M1
Aoi, Y; Furuya, R; Kamiya, Y; Shioda, M; Yamada, Y1
Cunha-Melo, JR; da Conceição, SA; da Luz, MM; de Araújo, GK; Lisboa, FA; Melo, JR; Moraes-Santos, T1
Branga, P; Coelho, D; Fernandes, T; Malheiro, D; Rodrigues, J1
Anic, T; Batelja, L; Berkopic, L; Blagaic Boban, A; Brcic, L; Cesarec, V; Coric, M; Dolovski, Z; Drmic, D; Ilic, S; Ivica, M; Klicek, R; Kocman, I; Kolenc, D; Lovric Bencic, M; Mise, S; Radic, B; Seiwerth, S; Sever, M; Sikiric, P; Skorjanec, S; Staresinic, M; Tonkic, A; Zoricic, I1
Czimmer, J; Mózsik, G; Szabó, IL; Szolcsányi, J1
Hrycevych, N; Pshyk-Titko, I; Savytska, M; Zayachkivska, O1

Reviews

3 review(s) available for atropine and ranitidine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Aspiration pneumonitis: predisposing conditions and prevention.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 1986, Volume: 44, Issue:5

    Topics: Atropine; Cimetidine; Citrates; Citric Acid; Duodenal Ulcer; Esophagogastric Junction; Gastric Acid; Gastroesophageal Reflux; Gastrointestinal Contents; Humans; Hydrogen-Ion Concentration; Larynx; Metoclopramide; Pneumonia, Aspiration; Pressure; Ranitidine; Stress, Psychological

1986
Molecular pharmacological approaches to effects of capsaicinoids and of classical antisecretory drugs on gastric basal acid secretion and on indomethacin-induced gastric mucosal damage in human healthy subjects (mini review).
    Current pharmaceutical design, 2013, Volume: 19, Issue:1

    Topics: Adult; Afferent Pathways; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Atropine; Capsaicin; Cimetidine; Dose-Response Relationship, Drug; Famotidine; Female; Gastric Acid; Gastric Mucosa; Humans; Indomethacin; Male; Omeprazole; Peptic Ulcer; Ranitidine

2013

Trials

3 trial(s) available for atropine and ranitidine

ArticleYear
Gastric fluid volume, pH, and emptying in elective inpatients. Influences of narcotic-atropine premedication, oral fluid, and ranitidine.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1988, Volume: 35, Issue:6

    Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Atropine; Drinking; Gastric Acidity Determination; Gastric Emptying; Gastric Juice; Humans; Hydrogen-Ion Concentration; Middle Aged; Morphine; Phenolsulfonphthalein; Preanesthetic Medication; Ranitidine

1988
Normal and disturbed motility pattern in the duodenum of man. The effect of l-hyoscyamine, trimipramine and ranitidine on the maximal pressure waves.
    Scandinavian journal of gastroenterology. Supplement, 1981, Volume: 67

    Topics: Adult; Atropine; Bile Reflux; Dibenzazepines; Duodenum; Furans; Gastrointestinal Motility; Histamine H2 Antagonists; Humans; Ranitidine; Transducers, Pressure; Trimipramine

1981
Molecular pharmacological approaches to effects of capsaicinoids and of classical antisecretory drugs on gastric basal acid secretion and on indomethacin-induced gastric mucosal damage in human healthy subjects (mini review).
    Current pharmaceutical design, 2013, Volume: 19, Issue:1

    Topics: Adult; Afferent Pathways; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Atropine; Capsaicin; Cimetidine; Dose-Response Relationship, Drug; Famotidine; Female; Gastric Acid; Gastric Mucosa; Humans; Indomethacin; Male; Omeprazole; Peptic Ulcer; Ranitidine

2013

Other Studies

63 other study(ies) available for atropine and ranitidine

ArticleYear
Synthesis and cholinergic properties of bis[[(dimethylamino)methyl]furanyl] analogues of ranitidine.
    Journal of medicinal chemistry, 1992, Mar-20, Volume: 35, Issue:6

    Topics: Animals; Cholinesterase Inhibitors; Furans; Humans; Male; Mice; Parasympathomimetics; Ranitidine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Structure-Activity Relationship

1992
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Determination of log D via automated microfluidic liquid-liquid extraction.
    Journal of medicinal chemistry, 2008, Aug-28, Volume: 51, Issue:16

    Topics: Automation; Biopharmaceutics; Microfluidic Analytical Techniques; Pharmacokinetics

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Influence of gastric acid on circulating somatostatin-14 and -28 released after insulin-induced hypoglycemia in conscious dogs.
    Endocrinology, 1992, Volume: 131, Issue:3

    Topics: Animals; Atropine; Blood Glucose; Chromatography, Gel; Dogs; Gastric Acid; Hypoglycemia; Insulin; Omeprazole; Pancreatic Polypeptide; Ranitidine; Somatostatin; Somatostatin-28; Time Factors

1992
Effect of histamine and histamine analogues on human isolated myometrial strips.
    British journal of pharmacology, 1992, Volume: 107, Issue:2

    Topics: Acetylcholine; Adult; Atropine; Benzimidazoles; Dose-Response Relationship, Drug; Female; Histamine; Histamine Agonists; Humans; Methylhistamines; Middle Aged; Muscle Relaxation; Muscle, Smooth; Myometrium; Potassium Chloride; Pyridines; Ranitidine; Uterine Contraction

1992
Mechanism of action of atracurium on airways.
    Anesthesiology, 1992, Volume: 76, Issue:3

    Topics: Airway Resistance; Animals; Atracurium; Atropine; Blood Pressure; Chlorpheniramine; Dogs; Heart Rate; Histamine; Histamine Release; Injections, Intravenous; Ranitidine

1992
Gastric acid and pepsin hypersecretion in conscious rabbits.
    The American journal of physiology, 1991, Volume: 261, Issue:2 Pt 1

    Topics: Animals; Atropine; Bethanechol; Bethanechol Compounds; Gastric Acid; Gastric Juice; Histamine; Male; Omeprazole; Pepsin A; Rabbits; Ranitidine; Stimulation, Chemical; Vagotomy

1991
The effect of CCKB/gastrin antagonists on stimulated gastric acid secretion in the anaesthetized rat.
    British journal of pharmacology, 1991, Volume: 104, Issue:4

    Topics: Animals; Anti-Anxiety Agents; Atropine; Benzodiazepinones; Bethanechol Compounds; Cholecystokinin; Dose-Response Relationship, Drug; Gastric Acid; Gastrins; Histamine; Indoles; Male; Meglumine; Omeprazole; Phenylurea Compounds; Ranitidine; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin

1991
Inhibition of acid secretion in guinea pigs by tricyclic antidepressants: comparison with ranitidine and omeprazole.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:2

    Topics: Adenosine Triphosphatases; Animals; Atropine; Gastric Acid; Guinea Pigs; H(+)-K(+)-Exchanging ATPase; Imipramine; In Vitro Techniques; Male; Omeprazole; Parietal Cells, Gastric; Promethazine; Ranitidine

1988
The effect of H2-receptor antagonists on pepsin secretion in man.
    Progress in clinical and biological research, 1985, Volume: 173

    Topics: Atropine; Cimetidine; Duodenal Ulcer; Gastric Mucosa; Histamine H2 Antagonists; Humans; Pepsin A; Ranitidine; Secretory Rate

1985
Gastric lesion-preventing or -potentiating activity of clonidine in rats.
    Japanese journal of pharmacology, 1986, Volume: 41, Issue:2

    Topics: Animals; Anti-Ulcer Agents; Atropine; Clonidine; Dimaprit; Female; Ranitidine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Stomach Ulcer; Thiourea

1986
Cephalic phase of gastroduodenal alkaline secretion.
    The American journal of physiology, 1987, Volume: 252, Issue:6 Pt 1

    Topics: Animals; Atropine; Bicarbonates; Dinoprostone; Dogs; Gastric Mucosa; Hydrogen-Ion Concentration; Indomethacin; Intestinal Mucosa; Propranolol; Prostaglandins E; Ranitidine; Sodium; Sodium Bicarbonate; Vagus Nerve

1987
First-degree atrioventricular block in a young duodenal ulcer patient treated with a standard oral dose of ranitidine.
    Agents and actions, 1988, Volume: 24, Issue:3-4

    Topics: Administration, Oral; Adult; Atropine; Duodenal Ulcer; Electrocardiography; Heart Block; Humans; Male; Ranitidine

1988
The inhibition of acetylcholinesterase by ranitidine: a study on the guinea pig ileum.
    Journal of pharmacobio-dynamics, 1986, Volume: 9, Issue:11

    Topics: Acetylcholine; Animals; Atropine; Cholinesterase Inhibitors; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Physostigmine; Ranitidine

1986
Acetylcholine mediation of the contractile response to histamine in human bladder detrusor muscle.
    European journal of pharmacology, 1987, Oct-06, Volume: 142, Issue:1

    Topics: Acetylcholine; Atropine; Dimethindene; Diphenhydramine; Histamine; Humans; In Vitro Techniques; Muscle, Smooth; Neostigmine; Ranitidine; Urinary Bladder

1987
Effect of ranitidine given before atropine sulphate on lower oesophageal sphincter tone.
    Anaesthesia and intensive care, 1984, Volume: 12, Issue:2

    Topics: Atropine; Esophagogastric Junction; Humans; Manometry; Premedication; Ranitidine

1984
Effects of ranitidine and oxmetidine on gastrointestinal motility in conscious dog.
    Agents and actions, 1984, Volume: 15, Issue:3-4

    Topics: Animals; Atropine; Dogs; Female; Gastrointestinal Motility; Imidazoles; Ranitidine; Time Factors

1984
Comparison of the gastric cytoprotective properties of atropine, ranitidine and PGE2 in rats.
    European journal of pharmacology, 1984, Oct-30, Volume: 106, Issue:1

    Topics: Animals; Aspirin; Atropine; Dinoprostone; Ethanol; Female; Gastric Acid; Neostigmine; Parasympathomimetics; Prostaglandins E; Ranitidine; Rats; Rats, Inbred Strains; Stomach Ulcer

1984
Cholinergic effects of cimetidine and ranitidine.
    Pharmacological research communications, 1983, Volume: 15, Issue:5

    Topics: Acetylcholine; Animals; Anura; Atropine; Bethanechol; Bethanechol Compounds; Cimetidine; Drug Synergism; Furans; Guanidines; Guinea Pigs; Heart Rate; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Parasympathomimetics; Ranitidine; Rats

1983
Short-term and long-term effects of ranitidine and oxmetidine on gastrointestinal motility in sheep.
    Archives internationales de pharmacodynamie et de therapie, 1984, Volume: 268, Issue:1

    Topics: Animals; Atropine; Drug Interactions; Duodenum; Electromyography; Gastrointestinal Motility; Histamine H2 Antagonists; Imidazoles; Ranitidine; Sheep; Time Factors

1984
Inhibition of basal acid, chloride, and pepsin secretion in duodenal ulcer by graded doses of ranitidine and atropine with studies of pharmacokinetics of ranitidine.
    Gastroenterology, 1982, Volume: 82, Issue:6

    Topics: Adult; Aged; Anti-Ulcer Agents; Atropine; Chlorides; Dose-Response Relationship, Drug; Duodenal Ulcer; Furans; Gastric Acid; Humans; Kinetics; Male; Middle Aged; Pepsin A; Ranitidine

1982
Studies with specific agonists and antagonists of the role of histamine H1- and H2-receptor activation in the pathogenesis of gastric lesions in rats.
    Agents and actions, 1984, Volume: 14, Issue:2

    Topics: Aminopyridines; Animals; Atropine; Dimaprit; Drug Interactions; Female; Histamine; Pyridines; Pyrilamine; Ranitidine; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Stomach Ulcer; Thiourea

1984
Effects of prostaglandins on [Ca2+]i and adenylate cyclase activity in isolated porcine gastric mucous cells.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1994, Volume: 45, Issue:2

    Topics: Adenylyl Cyclases; Animals; Atropine; Bucladesine; Calcium; Carbachol; Cells, Cultured; Colforsin; Gastric Mucosa; Histamine; Prostaglandins; Proteins; Ranitidine; Swine

1994
The role of thyrotropin-releasing hormone (TRH) in the pathogenesis of water-immersion stress in rats--inhibition of TRH release from the stomach by atropine, ranitidine or omeprazole.
    Gastroenterologia Japonica, 1993, Volume: 28, Issue:1

    Topics: Animals; Atropine; Bethanechol; Bethanechol Compounds; Gastric Acid; Gastric Juice; Gastric Mucosa; Immersion; Male; Omeprazole; Ranitidine; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Stress, Physiological; Thyrotropin-Releasing Hormone

1993
Histamine-induced, central nervous system-mediated hyperglycemia is suppressed by atropine in the brain.
    Life sciences, 1993, Volume: 52, Issue:15

    Topics: Animals; Atropine; Brain; Central Nervous System; Dose-Response Relationship, Drug; Histamine; Histamine Antagonists; Hyperglycemia; Injections, Intraventricular; Male; Neurotransmitter Agents; Pyrilamine; Ranitidine; Rats; Rats, Wistar; Receptors, Muscarinic

1993
Involvement of central cholinergic muscarinic receptors and histamine H1 receptors in hyperglycemia induced by prostaglandin F2 alpha in rats.
    Neuroendocrinology, 1993, Volume: 57, Issue:1

    Topics: Animals; Atropine; Dinoprost; Diphenhydramine; Histamine H1 Antagonists; Hyperglycemia; Injections, Intraventricular; Male; Muscarinic Antagonists; Pyrilamine; Ranitidine; Rats; Rats, Wistar; Receptors, Muscarinic

1993
Analysis of regional hemodynamic regulation in response to scald injury.
    The Journal of clinical investigation, 1994, Volume: 93, Issue:1

    Topics: Adamantane; Animals; Arginine; Atropine; Blood Pressure; Burns; Diphenhydramine; Dogs; Femoral Artery; Hemodynamics; Hindlimb; Histamine; Isoproterenol; Meclofenamic Acid; Methoxamine; Methysergide; Morpholines; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitroglycerin; Pulmonary Circulation; Ranitidine; Regional Blood Flow; Ritanserin; Serotonin; Serotonin Receptor Agonists; Time Factors; Triazines; Ultrasonography; Vascular Resistance; Vasodilation; Verapamil; Xanthines

1994
Inhibition of choline uptake in syncytial microvillus membrane vesicles of human term placenta. Specificity and nature of interaction.
    Biochemical pharmacology, 1995, Nov-27, Volume: 50, Issue:11

    Topics: Atropine; Carrier Proteins; Choline; Cholinergic Antagonists; Cimetidine; Dose-Response Relationship, Drug; Famotidine; Female; Hemicholinium 3; Histamine H2 Antagonists; Humans; In Vitro Techniques; Maternal-Fetal Exchange; Membrane Transport Proteins; Microvilli; Neurotransmitter Uptake Inhibitors; Placenta; Pregnancy; Ranitidine; Tetraethylammonium Compounds; Trophoblasts

1995
Effects of submucosal administration of endothelin-3 on rat gastric mucosa.
    Journal of gastroenterology, 1997, Volume: 32, Issue:2

    Topics: Animals; Anti-Ulcer Agents; Atropine; Dose-Response Relationship, Drug; Endothelin-3; Enzyme Inhibitors; Epinephrine; Gastric Mucosa; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Norepinephrine; Pirenzepine; Premedication; Ranitidine; Rats; Rats, Sprague-Dawley; Time Factors; Vagotomy

1997
Pentadecapeptide BPC 157, cimetidine, ranitidine, bromocriptine, and atropine effect in cysteamine lesions in totally gastrectromized rats: a model for cytoprotective studies.
    Digestive diseases and sciences, 1997, Volume: 42, Issue:5

    Topics: Animals; Anti-Ulcer Agents; Atropine; Bromocriptine; Cimetidine; Cysteamine; Duodenal Ulcer; Female; Gastrectomy; Omeprazole; Peptide Fragments; Proteins; Ranitidine; Rats; Rats, Wistar

1997
Determination of compatibility and stability of drugs used in palliative care.
    Journal of clinical pharmacy and therapeutics, 1998, Volume: 23, Issue:4

    Topics: Atropine; Butylscopolammonium Bromide; Drug Interactions; Drug Stability; Drug Therapy, Combination; Humans; Metoclopramide; Morphine; Palliative Care; Ranitidine; Terminal Care

1998
New model of cytoprotection/adaptive cytoprotection in rats: endogenous small irritants, antiulcer agents and indomethacin.
    European journal of pharmacology, 1999, Jan-01, Volume: 364, Issue:1

    Topics: Amino Acid Sequence; Anastomosis, Surgical; Animals; Anti-Ulcer Agents; Atropine; Cyclooxygenase Inhibitors; Cytoprotection; Dose-Response Relationship, Drug; Ethanol; Gastric Mucosa; Indomethacin; Irritants; Jejunum; Male; Molecular Sequence Data; Omeprazole; Peptic Ulcer; Peptide Fragments; Proteins; Ranitidine; Rats; Rats, Wistar; Stomach

1999
[Common variable immunodeficiency associated with autoimmune thrombocytopenia: anesthetic management].
    Revista espanola de anestesiologia y reanimacion, 1998, Volume: 45, Issue:10

    Topics: Adjuvants, Anesthesia; Adult; Aminocaproic Acid; Androstanols; Anesthesia, Inhalation; Anesthetics; Atropine; Autoimmune Diseases; Bromazepam; Combined Modality Therapy; Common Variable Immunodeficiency; Fentanyl; Fissure in Ano; Granulocyte Colony-Stimulating Factor; Hemorrhoids; Humans; Hypnotics and Sedatives; Immunoglobulins, Intravenous; Laryngeal Masks; Male; Methyl Ethers; Nitrous Oxide; Platelet Transfusion; Postoperative Complications; Preanesthetic Medication; Pregnenediones; Propofol; Purpura, Thrombocytopenic, Idiopathic; Ranitidine; Rocuronium; Sevoflurane; Thrombocytopenia

1998
Unexpected hyperkalemia following succinylcholine administration in prolonged immobilized parturients treated with magnesium and ritodrine.
    Anesthesiology, 2000, Volume: 93, Issue:6

    Topics: Adult; Analgesics; Anesthetics, Intravenous; Atropine; Female; Humans; Hyperkalemia; Magnesium; Magnesium Sulfate; Neuromuscular Depolarizing Agents; Obstetric Labor, Premature; Preanesthetic Medication; Pregnancy; Pregnancy Complications, Cardiovascular; Ranitidine; Ritodrine; Succinylcholine; Thiamylal

2000
[Effects of acetylcholine and histamine on leukocyte and neutrophil numbers in the endometrium of rats in various phases of the estrous cycle (by imprints)].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2000, Volume: 86, Issue:12

    Topics: Acetylcholine; Animals; Atropine; Carbamates; Carbolines; Cell Count; Cholinesterase Inhibitors; Diestrus; Endometrium; Estrus; Female; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Lymphocytes; Muscarinic Antagonists; Neuroimmunomodulation; Neutrophils; Pyridines; Pyridostigmine Bromide; Ranitidine; Rats; Rats, Wistar

2000
Haloperidol-stomach lesions attenuation by pentadecapeptide BPC 157, omeprazole, bromocriptine, but not atropine, lansoprazole, pantoprazole, ranitidine, cimetidine and misoprostol in mice.
    Life sciences, 2001, Mar-09, Volume: 68, Issue:16

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Atropine; Benzimidazoles; Bromocriptine; Cimetidine; Disease Models, Animal; Domperidone; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Indomethacin; Lansoprazole; Male; Mice; Mice, Inbred Strains; Misoprostol; Omeprazole; Pantoprazole; Peptide Fragments; Proteins; Ranitidine; Stomach Diseases; Sulfoxides

2001
Effects of two newly synthesized analogues of lidocaine on rat arterial blood pressure and heart rate.
    Pharmacological research, 2001, Volume: 43, Issue:4

    Topics: Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Atropine; Benzoates; Blood Pressure; Calcium Chloride; Cyproheptadine; Enzyme Inhibitors; Heart Rate; Hexamethonium; Histamine Agonists; Indomethacin; Lidocaine; Male; Monitoring, Physiologic; NG-Nitroarginine Methyl Ester; Pyrilamine; Quinacrine; Ranitidine; Rats; Rats, Wistar; Vasodilator Agents

2001
Different effect of antiulcer agents on rat cysteamine-induced duodenal ulcer after sialoadenectomy, but not gastrectomy.
    European journal of pharmacology, 2003, Sep-05, Volume: 477, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Atropine; Cysteamine; Duodenal Ulcer; Female; Gastrectomy; Omeprazole; Peptide Fragments; Proteins; Ranitidine; Rats; Rats, Wistar; Submandibular Gland

2003
Pre-anesthetic evaluation can play a crucial role in the determination of airway management in a child with oropharyngeal tumor.
    Journal of anesthesia, 2006, Volume: 20, Issue:3

    Topics: Airway Obstruction; Anesthetics, Intravenous; Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Anti-Ulcer Agents; Atropine; Child; Female; Fentanyl; Fiber Optic Technology; Hemangioma; Humans; Hydrocortisone; Intubation, Intratracheal; Laryngoscopy; Oropharyngeal Neoplasms; Oropharynx; Posture; Preoperative Care; Ranitidine; Rare Diseases; Tomography, X-Ray Computed

2006
Effect of acid secretion blockade on acute gastric mucosal lesions induced by Tityus serrulatus scorpion toxin in anaesthetized rats.
    Toxicon : official journal of the International Society on Toxinology, 2006, Volume: 48, Issue:5

    Topics: Acute Disease; Anesthesia; Animals; Atropine; Cimetidine; Dose-Response Relationship, Drug; Drug Antagonism; Enzyme Inhibitors; Gastric Acid; Gastric Mucosa; Gastrointestinal Agents; Male; Neurotoxins; Octreotide; Omeprazole; Pepsin A; Ranitidine; Rats; Scorpion Venoms; Stomach Diseases

2006
Intraoperative anaphylaxis after intravenous atropine.
    European journal of anaesthesiology, 2007, Volume: 24, Issue:3

    Topics: Adjuvants, Anesthesia; Aged; Anaphylaxis; Anesthesia, General; Anti-Inflammatory Agents; Atropine; Blood Pressure; Cholinesterase Inhibitors; Clemastine; Elective Surgical Procedures; Heart Rate; Histamine Antagonists; Humans; Hydrocortisone; Injections, Intravenous; Intraoperative Complications; Lumbar Vertebrae; Male; Neostigmine; Norepinephrine; Ranitidine; Skin Tests; Vasoconstrictor Agents

2007
Therapy for unhealed gastrocutaneous fistulas in rats as a model for analogous healing of persistent skin wounds and persistent gastric ulcers: stable gastric pentadecapeptide BPC 157, atropine, ranitidine, and omeprazole.
    Digestive diseases and sciences, 2009, Volume: 54, Issue:1

    Topics: Adrenal Cortex Hormones; Animals; Anti-Ulcer Agents; Atropine; Cutaneous Fistula; Disease Models, Animal; Gastric Fistula; Gastric Mucosa; Male; Omeprazole; Peptide Fragments; Proteins; Ranitidine; Rats; Rats, Wistar; Stomach Ulcer; Wound Healing

2009
New insight into oseophageal injury and protection in physiologically relevant animal models.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2014, Volume: 65, Issue:2

    Topics: Animals; Atropine; Cytokines; Disease Models, Animal; Esophagitis, Peptic; Esophagus; Histamine H2 Antagonists; Hyperglycemia; Intestinal Mucosa; Mouth Mucosa; Muscarinic Antagonists; Nitric Oxide; Nitric Oxide Synthase; Ranitidine; Rats

2014