Compounds > atropine

Page last updated: 2024-09-05

atropine and quinuclidinyl benzilate

atropine has been researched along with quinuclidinyl benzilate in 8 studies

Compound Research Comparison

Studies (atropine)	Trials (atropine)	Recent Studies (post-2010) (atropine)	Studies (quinuclidinyl benzilate)	Trials (quinuclidinyl benzilate)	Recent Studies (post-2010) (quinuclidinyl benzilate)
26,711	1,259	1,697	17	0	5
26,711	1,259	1,697	5	0	0

Protein Interaction Comparison

Protein	Taxonomy	atropine (IC50)	quinuclidinyl benzilate (IC50)
Muscarinic acetylcholine receptor M2	Homo sapiens (human)		0.0004
Muscarinic acetylcholine receptor M1	Homo sapiens (human)		0.0004
Muscarinic acetylcholine receptor M3	Homo sapiens (human)		0.0009

Research

Studies (8)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (62.50)	18.7374
1990's	3 (37.50)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ashkenazi, A; Capon, DJ; Peralta, EG; Ramachandran, J; Smith, DH; Winslow, JW	1
Abraham, P; Ahmad, A; Carroll, FI; Chiang, PK; Griffith, RC; Padilla, FN; Parham, K; Richard, MM; Witkin, JM	1
Aceto, MD; Archer, S; Atkinson, ER; Harris, LS; Luduena, FP; McRitchie-Ticknor, DD; Pearl, J	1
Eckelman, WC; Ferreira, NL; Gibson, RE; Jagoda, EM; Reba, RC; Rzeszotarski, WJ; Simms, DA	1
Brisander, M; Hacksell, U; Johansson, G; Nilsson, BM; Nilvebrant, L; Nordvall, G; Sundquist, S	1
DeHaven-Hudkins, DL; Hudkins, RL; Stubbins, JF	1
Ferkany, JW; Kinnier, WJ; Kirkien-Rzeszotarski, A; McPherson, DW; Noronha-Blob, L; Rzeszotarski, WJ	1
Callahan, AP; DeHaven-Hudkins, DL; Knapp, FF; McPherson, DW	1

Other Studies

8 other study(ies) available for atropine and quinuclidinyl benzilate

Article	Year
Distinct primary structures, ligand-binding properties and tissue-specific expression of four human muscarinic acetylcholine receptors. The EMBO journal, 1987, Dec-20, Volume: 6, Issue:13 Topics: Amino Acid Sequence; Cloning, Molecular; Genes; Humans; Kinetics; Molecular Sequence Data; Receptors, Muscarinic; Transcription, Genetic	1987
6-Methyl-6-azabicyclo[3.2.1]octan-3 alpha-ol 2,2-diphenylpropionate (azaprophen), a highly potent antimuscarinic agent. Journal of medicinal chemistry, 1987, Volume: 30, Issue:5 Topics: Acetylcholine; alpha-Amylases; Animals; Behavior, Animal; Carbachol; Cell Line; Chemical Phenomena; Chemistry; Guinea Pigs; Humans; Male; Molecular Conformation; Muscle Contraction; Neuroblastoma; Pancreas; Phenylpropionates; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine; Tropanes	1987
Parasympatholytic (anticholinergic) esters of the isomeric 2-tropanols. 2. Non-glycolates. Journal of medicinal chemistry, 1983, Volume: 26, Issue:12 Topics: Animals; Atropine; Mice; Parasympatholytics; Pupil; Tremorine; Tropanes	1983
Analogues of 3-quinuclidinyl benzilate. Journal of medicinal chemistry, 1982, Volume: 25, Issue:9 Topics: Animals; Binding, Competitive; Chemical Phenomena; Chemistry; Dogs; In Vitro Techniques; Myocardial Contraction; Quinuclidines; Quinuclidinyl Benzilate; Rats; Receptors, Muscarinic	1982
Antimuscarinic 3-(2-furanyl)quinuclidin-2-ene derivatives: synthesis and structure-activity relationships. Journal of medicinal chemistry, 1997, Nov-07, Volume: 40, Issue:23 Topics: Animals; Binding, Competitive; Cerebral Cortex; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Molecular Conformation; Muscarinic Antagonists; Muscle, Smooth; Myocardium; Parotid Gland; Quinuclidines; Quinuclidinyl Benzilate; Radioligand Assay; Receptors, Muscarinic; Structure-Activity Relationship; Tritium; Urinary Bladder	1997
Muscarinic receptor binding profile of para-substituted caramiphen analogues. Journal of medicinal chemistry, 1991, Volume: 34, Issue:10 Topics: Animals; Binding, Competitive; Cerebral Cortex; Cyclopentanes; Male; Molecular Structure; Parasympatholytics; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Structure-Activity Relationship	1991
Affinity and selectivity of the optical isomers of 3-quinuclidinyl benzilate and related muscarinic antagonists. Journal of medicinal chemistry, 1988, Volume: 31, Issue:7 Topics: Adenylyl Cyclase Inhibitors; Animals; Cattle; Chemical Phenomena; Chemistry; Corpus Striatum; Inositol Phosphates; Male; Muscarine; Myocardium; Pirenzepine; Quinuclidines; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Stereoisomerism; Structure-Activity Relationship	1988
Synthesis and biodistribution of iodine-125-labeled 1-azabicyclo[2.2.2]oct-3-yl alpha-hydroxy-alpha-(1-iodo-1-propen-3-yl)-alpha-phenylacetate. A new ligand for the potential imaging of muscarinic receptors by single photon emission computed tomography. Journal of medicinal chemistry, 1993, Apr-02, Volume: 36, Issue:7 Topics: Animals; Brain; Female; Iodine Radioisotopes; Ligands; Quinuclidines; Quinuclidinyl Benzilate; Rats; Receptors, Muscarinic; Structure-Activity Relationship; Tissue Distribution; Tomography, Emission-Computed, Single-Photon	1993