Page last updated: 2024-09-05

atropine and quinine

atropine has been researched along with quinine in 42 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(quinine)
Trials
(quinine)
Recent Studies (post-2010) (quinine)
26,7111,2591,6976,8593981,099

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)quinine (IC50)
Solute carrier family 22 member 1Mus musculus (house mouse)0.28
Solute carrier family 22 member 2Mus musculus (house mouse)2.8
Potassium channel subfamily K member 2Homo sapiens (human)3.85
ATP-dependent translocase ABCB1Homo sapiens (human)1.7
Cytochrome P450 2D26Rattus norvegicus (Norway rat)0.094
Cytochrome P450 2D6Homo sapiens (human)0.6285
Solute carrier family 22 member 1Rattus norvegicus (Norway rat)2.0333
Cytochrome P450 2D4Rattus norvegicus (Norway rat)1.7

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199027 (64.29)18.7374
1990's1 (2.38)18.2507
2000's6 (14.29)29.6817
2010's8 (19.05)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Scott, WA; Solomon, B1
Price, NR; Williams, AJ1
Murgia, E; Walton, HF1
Ohmori, H; Shigemoto, T1
Esakov, AI; Serova, ON1
Mazor, EI1
Rentsch, G; Staubesand, J; Wittekind, D1
Dal Ri, H; Lendle, L; Schmidt, G1
Doctor, RB; Jindal, MN; Kelkar, VV1
Behnsen, G; Kühn, L; Pfeifer, S1
Greenhow, EJ; Spencer, LE1
Kawahara, Y; Yamada, S1
Chinard, FP; Effros, RM1
Acara, M; Rennick, B1
Hurwitz, A1
Carapancea, M1
Guillory, JK; Hwang, SC; Lach, JL1
Brochmann-Hanssen, E; Fontan, CR1
Wallace, V1
Mathews, PA; Sher, MH1
SCHACHTER, M1
BARR, M; EVCIM, N1
HAMMER, F1
DISTEFANO, R1
DAS, PK; SANYAL, AK; SINHA, PS1
IZAR, G1
Crawford, JW; Hogan, MJ1

Reviews

2 review(s) available for atropine and quinine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Epidemic Keratoconjunctivitis: (Superficial Punctate Keratitis, Keratitis Subepithelialis, Keratitis Maculosa, Keratitis Nummularis) With a Review of the Literature and a Report of 125 Cases.
    American journal of ophthalmology, 2018, Volume: 190

    Topics: Atropine; Diagnosis, Differential; Humans; Keratoconjunctivitis; Quinine; Radiotherapy; Sulfonamides; United States

2018

Other Studies

40 other study(ies) available for atropine and quinine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Adenosine 3',5'-cyclic monophosphate and morphology in Neurospora crassa: drug-induced alterations.
    Journal of bacteriology, 1975, Volume: 122, Issue:2

    Topics: Adenylyl Cyclases; Antimalarials; Atropine; Chloroquine; Cyclic AMP; Histamine; Kinetics; Neurospora; Neurospora crassa; Phosphoric Diester Hydrolases; Quinidine; Quinine; Theophylline

1975
An assay for inorganic orthophosphate in the presence of alkaloids and related drugs.
    Biochemical medicine, 1977, Volume: 17, Issue:2

    Topics: Alkaloids; Atropine; Caffeine; Methods; Molybdenum; Phosphates; Quinine; Theophylline

1977
Ligand-exchange chromatography of alkaloids.
    Journal of chromatography, 1975, Feb-12, Volume: 104, Issue:2

    Topics: Alkaloids; Atropine; Chromatography, Ion Exchange; Cinchona; Cinchona Alkaloids; Cocaine; Codeine; Copper; Hydrolysis; Ion Exchange Resins; Methadone; Methods; Morphine; Noscapine; Papaverine; Plants, Medicinal; Quinine; Strychnine

1975
Muscarinic receptor hyperpolarizes cochlear hair cells of chick by activating Ca(2+)-activated K+ channels.
    The Journal of physiology, 1991, Volume: 442

    Topics: Acetylcholine; Animals; Atropine; Calcium; Chickens; Dose-Response Relationship, Drug; Hair Cells, Auditory; Membrane Potentials; Potassium; Potassium Channels; Quinine; Receptors, Muscarinic

1991
[Activating effect of cholecystokinin-pancreozymin on the taste-receptor system of the rat].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1985, Volume: 71, Issue:10

    Topics: Animals; Atropine; Cholecystokinin; Chorda Tympani Nerve; Lypressin; Male; Quinine; Rats; Reaction Time; Sodium Chloride; Stimulation, Chemical; Sucrose; Taste; Taste Buds

1985
[Results of treating herpetic keratitis].
    Oftalmologicheskii zhurnal, 1971, Volume: 26, Issue:8

    Topics: Adult; Anti-Infective Agents, Local; Atropine; Autonomic Nerve Block; Ethyl Ethers; gamma-Globulins; Humans; Iodine; Keratitis, Dendritic; Methenamine; Methods; Middle Aged; Quinine; Vitamin B Complex

1971
Drugs in breast milk.
    The Medical letter on drugs and therapeutics, 1974, Mar-15, Volume: 16, Issue:6

    Topics: Anticoagulants; Anticonvulsants; Antineoplastic Agents; Antithyroid Agents; Aspirin; Atropine; Caffeine; Chloramphenicol; Chlorothiazide; Contraceptives, Oral; Ergot Alkaloids; Ethanol; Female; Humans; Hypnotics and Sedatives; Methadone; Milk, Human; Nalidixic Acid; Narcotics; Penicillins; Quinine; Reserpine; Sulfonamides; Tetracycline

1974
[Reaction with drugs of basophilic structures in young red blood cells].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1967, Volume: 257, Issue:1

    Topics: Animals; Atropine; Caffeine; Guinea Pigs; Heinz Bodies; Microscopy, Electron; Morphine; Organoids; Phenylhydrazines; Quinine; Reticulocytes; Ribosomes

1967
[Use of beta receptor inhibitors in atropine poisoning].
    Deutsche medizinische Wochenschrift (1946), 1966, Jul-22, Volume: 91, Issue:29

    Topics: Animals; Atropine; Cats; Electrocardiography; Ethanolamines; Humans; Parasympathomimetics; Pilocarpine; Quinine; Rabbits; Tachycardia

1966
Chlorpromazine-induced contracture of frog rectus abdominis muscle.
    Pharmacology, 1974, Volume: 12, Issue:1

    Topics: Acetylcholine; Adenosine; Animals; Arsenic; Atropine; Caffeine; Chlorpromazine; Choline; Cocaine; Cyanides; Electric Stimulation; Fluorides; Hexamethonium Compounds; In Vitro Techniques; Iodoacetates; Muscle Contraction; Ouabain; Physostigmine; Potassium Chloride; Procaine; Quinine; Sparteine; Stimulation, Chemical; Tubocurarine

1974
[Stability of alkaloids in organic solvents. 1].
    Die Pharmazie, 1972, Volume: 27, Issue:10

    Topics: Acetone; Alkaloids; Atropine; Benzene; Caffeine; Chloroform; Codeine; Darkness; Drug Stability; Ethanol; Light; Methanol; Morphine; Noscapine; Papaverine; Physostigmine; Pilocarpine; Quinine; Radiation; Reserpine; Scopolamine; Solvents; Temperature; Thebaine

1972
Ionic polymerisation as a means of end-point indication in non-aqueous thermometric titrimetry. 3. The determination of alkaloids and alkaloidal salts.
    The Analyst, 1973, Volume: 98, Issue:163

    Topics: Alkaloids; Atropine; Caffeine; Codeine; Ephedrine; Indicators and Reagents; Methods; Microchemistry; Nicotine; Papaverine; Polymers; Quinine; Salts; Strychnine; Temperature; Theophylline

1973
[Pharmacological studies on the vascular system of the human placenta].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1974, Volume: 70, Issue:2

    Topics: Acetylcholine; Atropine; Blood Vessels; Caffeine; Carbon Dioxide; Ephedrine; Epinephrine; Ergotamine; Female; Histamine; Humans; Isoproterenol; Nicotine; Norepinephrine; Oxygen; Oxytocin; Papaverine; Perfusion; Phenoxybenzamine; Pilocarpine; Placenta; Pregnancy; Propranolol; Quinine; Serotonin

1974
The in vivo pH of the extravascular space of the lung.
    The Journal of clinical investigation, 1969, Volume: 48, Issue:11

    Topics: Amines; Aniline Compounds; Animals; Antipyrine; Atropine; Carbon Dioxide; Dogs; Dye Dilution Technique; Guanidines; Histamine; Hydrogen-Ion Concentration; Indicator Dilution Techniques; Ketones; Lung; Mathematics; Mescaline; Morphine; Nicotine; Oxyphenbutazone; Partial Pressure; Quinine; Radioisotope Dilution Technique; Tritium

1969
Renal tubular transport of acetylcholine and atropine: enhancement an inhibition.
    The Journal of pharmacology and experimental therapeutics, 1972, Volume: 182, Issue:1

    Topics: Acetates; Acetylcholine; Alkenes; Animals; Atropine; Benzoxazoles; Biological Transport, Active; Carbon Isotopes; Chickens; Choline; Cholinesterase Inhibitors; Chromatography, Paper; Cocaine; Coloring Agents; Depression, Chemical; Electrophoresis; Female; Kidney Tubules; Kinetics; Paraoxon; Physostigmine; Quinine; Stimulation, Chemical; Tritium

1972
The effects of antacids on gastrointestinal drug absorption. II. Effect on sulfadiazine and quinine.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 179, Issue:3

    Topics: Aluminum; Aluminum Hydroxide; Animals; Antacids; Atropine; Chlorides; Hydrogen-Ion Concentration; Hydroxides; Intestinal Absorption; Kinetics; Magnesium; Male; Quinine; Rats; Rats, Inbred Strains; Solubility; Sulfadiazine

1971
[Aspects of some pharmacodynamic, clinical and experimental imbalances of iridomotor homeostasis].
    Fiziologia normala si patologica, 1969, Volume: 15, Issue:3

    Topics: Amphetamine; Animals; Atmospheric Pressure; Atropine; Chloral Hydrate; Ciliary Body; Digitalis Glycosides; Epinephrine; Iris; Miotics; Mydriatics; Oculomotor Muscles; Physostigmine; Pilocarpine; Pupil; Quinine; Strychnine

1969
Interactions between pharmaceutical compounds by thermal methods.
    Journal of pharmaceutical sciences, 1969, Volume: 58, Issue:3

    Topics: Acetaminophen; Aspirin; Atropine; Bile Acids and Salts; Caffeine; Drug Compounding; Drug Incompatibility; Drug Stability; Methods; Phenacetin; Phenobarbital; Phenytoin; Quinine; Temperature; Theophylline; Thermodynamics; Time Factors; Vitamin K

1969
Gas chromatography of alkaloids with polar stationary liquids.
    Journal of chromatography, 1965, Volume: 19, Issue:2

    Topics: Alkaloids; Atropine; Chromatography, Gas; Cinchona; Cocaine; Codeine; Morphine; Papaverine; Pilocarpine; Plants, Medicinal; Quinidine; Quinine; Scopolamine; Strychnine; Thebaine

1965
Rapid automated analysis involving liquid-liquid extraction: atropine by a Prudhomme method.
    Analytical biochemistry, 1967, Volume: 20, Issue:3

    Topics: Atropine; Autoanalysis; Chloroform; Colorimetry; Coloring Agents; Quinine

1967
Recurarization with quinine administration after reversal from anaesthesia.
    Anaesthesia and intensive care, 1983, Volume: 11, Issue:3

    Topics: Atropine; Drug Interactions; Humans; Male; Middle Aged; Neostigmine; Nerve Block; Neuromuscular Junction; Neuromuscular Nondepolarizing Agents; Pancreatic Pseudocyst; Pancuronium; Postoperative Complications; Quinine; Respiratory Insufficiency

1983
The release of histamine by pethidine, atropine, quinine, and other drugs.
    British journal of pharmacology and chemotherapy, 1952, Volume: 7, Issue:4

    Topics: Arsphenamine; Atropine; Histamine; Humans; Meperidine; Quinine; Sympatholytics

1952
Adsorption of some alkaloids by different clays.
    Journal of the American Pharmaceutical Association. American Pharmaceutical Association, 1955, Volume: 44, Issue:9

    Topics: Adsorption; Alkaloids; Aluminum Silicates; Atropine; Cinchona; Clay; Quinine; Strychnine

1955
[On the treatment of functional and organic heart diseases from the internist's viewpoint].
    Arzneimittel-Forschung, 1962, Volume: 12

    Topics: Alkaloids; Atropine; Heart Diseases; Hypnotics and Sedatives; Papaverine; Phenobarbital; Quinine; Rauwolfia

1962
[MYASTHENIC SYNDROMES].
    Prensa medica argentina, 1963, Jun-28, Volume: 50

    Topics: Atropine; Autoimmune Diseases; Diagnosis; Electromyography; Lambert-Eaton Myasthenic Syndrome; Muscular Diseases; Myasthenia Gravis; Neostigmine; Parasympathomimetics; Pathology; Pralidoxime Compounds; Quinine; Ventilators, Mechanical

1963
STUDIES ON CILIARY MOVEMENTS: I. MECHANISM OF CILIARY MOVEMENT IN FROG'S OESOPHAGUS.
    Archives internationales de pharmacodynamie et de therapie, 1964, Aug-01, Volume: 150

    Topics: Acetylcholine; Animals; Anura; Atropine; Cilia; Epinephrine; Ergotamine; Esophagus; Histamine; Lidocaine; Movement; Nicotine; Pentolinium Tartrate; Pharmacology; Physostigmine; Procaine; Quinine; Research; Sympathetic Nervous System; Tolazoline

1964
[ARRHYTMIA: DIAGNOSIS AND TREATMENT].
    Minerva medica, 1964, Oct-10, Volume: 55

    Topics: Amyl Nitrite; Arrhythmias, Cardiac; Atropine; Diagnosis; Digitalis Glycosides; Drug Therapy; Ephedrine; Epinephrine; Humans; Ouabain; Physostigmine; Pilocarpine; Quinidine; Quinine; Strophanthins

1964