Page last updated: 2024-09-05

atropine and pregnanolone

atropine has been researched along with pregnanolone in 6 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(pregnanolone)
Trials
(pregnanolone)
Recent Studies (post-2010) (pregnanolone)
26,7111,2591,6971,984111666

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)pregnanolone (IC50)
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)0.101
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)0.101
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)0.101
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)0.101
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)0.101
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)0.101
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)0.101
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)0.101
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)0.117
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)0.101
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)0.101
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)0.101
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)0.117
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.117
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.117
Gamma-aminobutyric acid receptor subunit alpha-1Mus musculus (house mouse)0.071
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)0.101
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)0.101
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)0.101
GABA theta subunitRattus norvegicus (Norway rat)0.101
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)0.101

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19904 (66.67)18.7374
1990's1 (16.67)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chapman, JM; Cooper, GM; Gray, AJ; Prys-Roberts, C; Sear, JW; Simpson, PJ1
Lumley, J; Morgan, M; Punchihewa, VG; Whitwam, JG1
Lumley, J; Morgan, M; Puchihewa, VG; Whitwam, JG1
Evans, DF; Foster, GE; Healy, TE; Syed, A1
Bäckström, T; Johansson, S; Landgren, S; Wang, MD1

Trials

1 trial(s) available for atropine and pregnanolone

ArticleYear
Initial experience with Minaxolone. A water-soluble steroid intravenous anaesthetic agent.
    Anaesthesia, 1980, Volume: 35, Issue:2

    Topics: Adult; Anesthesia, Intravenous; Atropine; Blood Pressure; Female; Fentanyl; Humans; Nitrous Oxide; Pregnanes; Pregnanolone; Pulse

1980

Other Studies

5 other study(ies) available for atropine and pregnanolone

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Studies on premedication and ventilatory responses to minaxolone.
    Acta anaesthesiologica Belgica, 1981, Volume: 32, Issue:2

    Topics: Adult; Anesthetics; Atropine; Diazepam; Female; Humans; Male; Morphine; Nitrous Oxide; Oxygen; Preanesthetic Medication; Pregnanes; Pregnanolone; Respiration; Time Factors

1981
Respiratory effects of Minaxolone.
    Anaesthesia, 1980, Volume: 35, Issue:6

    Topics: Anesthesia, Intravenous; Anesthetics; Apnea; Atropine; Female; Humans; Lorazepam; Lung Volume Measurements; Papaverine; Preanesthetic Medication; Pregnanes; Pregnanolone; Respiration; Scopolamine

1980
Effect of some i.v. anaesthetic agents on canine gastrointestinal motility.
    British journal of anaesthesia, 1981, Volume: 53, Issue:3

    Topics: Action Potentials; Anesthesia, Intravenous; Anesthetics; Animals; Atropine; Dogs; Gastrointestinal Motility; Intestine, Small; Ketamine; Pentolinium Tartrate; Pregnanes; Pregnanolone; Thiopental

1981
Interaction between 3 alpha-hydroxy-5 alpha-pregnan-20-one and carbachol in the control of neuronal excitability in hippocampal slices of female rats in defined phases of the oestrus.
    Acta physiologica Scandinavica, 1998, Volume: 162, Issue:1

    Topics: Action Potentials; Animals; Atropine; Carbachol; Drug Synergism; Estradiol; Estrus; Female; GABA Antagonists; GABA Modulators; Hippocampus; Muscarinic Agonists; Muscarinic Antagonists; Neurons; Picrotoxin; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A

1998