atropine has been researched along with pralidoxime in 225 studies
| Studies (atropine) | Trials (atropine) | Recent Studies (post-2010) (atropine) | Studies (pralidoxime) | Trials (pralidoxime) | Recent Studies (post-2010) (pralidoxime) |
|---|---|---|---|---|---|
| 26,711 | 1,259 | 1,697 | 658 | 28 | 156 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 54 (24.00) | 18.7374 |
| 1990's | 50 (22.22) | 18.2507 |
| 2000's | 65 (28.89) | 29.6817 |
| 2010's | 49 (21.78) | 24.3611 |
| 2020's | 7 (3.11) | 2.80 |
| Authors | Studies |
|---|---|
| Beasley, VR; Fikes, JD; Parker, AJ; Zachary, JF | 1 |
| De Bleecker, J; Van Den Neucker, K; Willems, J | 1 |
| de Silva, HJ; Senanayake, N; Wijewickrema, R | 1 |
| Dochterman, LW; Gresham, VC; Kaminskis, A; Koplovitz, I; Stewart, JR | 1 |
| Awal, MA; Malik, JK | 1 |
| De Bleecker, J; De Reuck, J; Van Den Neucker, K; Vogelaers, D; Willems, J | 1 |
| Clement, JG | 1 |
| Brar, GK; Kumar, H; Singh, CP; Singh, N | 1 |
| McCart, GM; Poikonen, J; Veatch, RM | 1 |
| Mays, MZ; Murrow, ML; Romano, JA; Terry, MR | 1 |
| Shih, T; Valdes, JJ; Whalley, CE | 1 |
| Culp, DJ; Marin, MG; McBride, RK; Stone, KK; Zwierzynski, DJ | 1 |
| Anderson, DR; Harris, LW; Lennox, WJ; Lieske, CN | 1 |
| Johnson, RF; Kobrick, JL; McMenemy, DJ | 2 |
| Cadarette, BS; Kolka, MA | 1 |
| Heath, A; Meredith, TJ; Vale, JA | 1 |
| Baux, G; Fossier, P; Poulain, B; Tauc, L | 1 |
| Colardyn, F; De Wilde, V; Vogelaers, D | 1 |
| Juang, YC; Lan, RS; Lee, CH; Shieh, WB; Tsao, TC | 1 |
| Anderson, DR; Harris, LW; Lennox, WJ; Talbot, BG | 2 |
| Culp, DJ; Marin, MG; McBride, RK; Zwierzynski, D | 1 |
| Hänninen, O; Kaliste-Korhonen, E; Ryhänen, R; Ylitalo, P | 1 |
| Andre, RG; Golenda, CF; Roberts, DR; Wirtz, RA | 1 |
| Bonner, GD; Gildengorin, VL; Trail, DS; Wade, CE; Waring, PP; Williams, BF | 1 |
| Haegerstrom-Portnoy, G; Jones, RT; Penetar, DM | 1 |
| Doukas, PH; O'Neill, JJ; Sheldon, RJ; Sterling, GH | 1 |
| Borowitz, SM | 1 |
| Mortensen, ML | 1 |
| Garber, M | 1 |
| Malik, JK; Srivastava, AK | 1 |
| Bruttig, SP; Cadarette, BS; Gonzalez, RR; Kolka, MA; Stephenson, LA | 1 |
| Halle, A; Sloas, DD | 1 |
| Bokonjić, D; Jokanović, M; Jovanović, D; Maksimović, M | 1 |
| Bowles, AM; Dretchen, KL; Raines, A | 1 |
| Anderson, DR; Green, MD; Harris, LW; Lennox, WJ; Talbot, BG | 1 |
| Adams, AJ; Haegerstrom-Portnoy, G; Jampolsky, A; Jones, R | 1 |
| Cruickshank, AN; Kipling, RM | 1 |
| Donzanti, BA; Green, MD; Shores, EI | 1 |
| Klemm, WR | 1 |
| Anthony, A; Bocan, TM; Doebler, JA; Moore, RA; Shih, TM | 1 |
| Chow, E; Higgins, RJ; Hooper, M; Knaak, JB; Wilson, BW | 1 |
| Bosković, B; Cetković, S; Cosić, M; Cvetković, M; Jandrić, D | 1 |
| Green, PG; Kitchen, I | 1 |
| Bosković, B; Jovanović, D; Kovacević, V | 1 |
| Headley, DB | 1 |
| Clay, C; Stewart, GO | 1 |
| Delgado, M; Suazo, M | 1 |
| Goto, T; Ichikawa, S; Umetsu, N | 1 |
| Koplovitz, I; Young, GD | 1 |
| Bernay, I; Cantürk, F; Demirçali, AE; Sahin, M | 1 |
| Hillman, JV | 1 |
| Blick, DW; Brown, GC; Hartgraves, SL; Murphy, MR | 1 |
| Bahat, O; Bellaiche, M; Hanji, V; Heymann, GD; Lublin, A; Mechani, S; Nyska, A; Shlosberg, A | 1 |
| Almog, S; Lifshitz, M; Rotenberg, M; Shahak, E; Sofer, S; Tamiri, T | 1 |
| Koplovitz, I; Stewart, JR | 1 |
| Buckley, NA; Dawson, AH; Whyte, IM | 1 |
| Das Gupta, S; Pant, SC; Vijayaraghavan, R | 1 |
| Ghosh, AK; Jaiswal, DK; Sikder, AK | 1 |
| Beers, ET; Brennecke, LH; Sparenborg, S | 1 |
| Ayebo, AD; Fuortes, LJ; Kross, BC | 1 |
| Arai, T; Hatakenaka, S; Ochi, G; Tokuoka, H; Watanabe, K | 1 |
| Jokanović, M; Maksimović, M | 1 |
| Pei, L; Petrikovics, I; Way, JL | 1 |
| Barahona, MV; Sánchez-Fortún, S; Sanz, F | 1 |
| Baubichon, D; Blanchet, G; Brochier, G; Clarencon, D; Galonnier, M; Lallement, G; Mestries, JC | 1 |
| Anstead, MI; Tush, GM | 1 |
| Göktaş, Z; Güven, M; Kurtoğlu, S; Unlühizarci, K | 1 |
| Liang, J; Luo, C | 1 |
| Bellaiche, M; Ershov, E; Hanji, V; Shlosberg, A | 1 |
| Baubichon, D; Burckhart, MF; Clarençon, D; Galonnier, M; Lallement, G; Masqueliez, C; Mestries, JC; Peoc'h, M | 1 |
| Agouridakis, P; Anastasaki, M; Delaki, C; Katsanoulas, K; Manousakis, A; Tsatsakis, AM; Tzatzarakis, M | 1 |
| Ameri, A; Cezard, C; Forceville, X; Mathieu-Nolf, M; Nisse, P | 1 |
| Baubichon, D; Burckhart, MF; Clarençon, D; Galonnier, M; Lallement, G; Peoc'h, M | 1 |
| Chen, Y; Qin, F; Xu, H | 1 |
| McDonough, JH; Shih, TM | 1 |
| Baubichon, D; Burckhart, MF; Clarençon, D; Galonnier, M; Jourdil, N; Lallement, G; Peoc'h, M; Renault, F | 1 |
| Chavonnet, A; Daijardin, JB; Kintz, P; Pileire, B; Ragoucy-Sengler, C; Simonetti, M; Tracqui, A | 1 |
| Barahona, V; Sánchez-Fortún, S | 1 |
| DeRoos, F; Hoffman, RS; Nelson, LS; Perrone, J; Stork, C | 1 |
| Al-Mandhiry, ZA; Javad, H; Nair, PM | 1 |
| Lall, SB; Mittra, S; Peshin, SS | 1 |
| Flesch, F; Géraut, A; Jaeger, A; Ludes, B; Raul, JS; Sauder, P; Tracqui, A | 1 |
| Buckley, N; Eddleston, M; Eyer, P; Szinicz, L | 1 |
| Bertsias, GK; Liakou, V; Mammas, IN; Stiakakis, I; Tsatsakis, AM; Tzanakakis, GN | 1 |
| Go, ML; Loke, WK; Sim, MK | 2 |
| Huang, S; Qiu, Z; Shi, Y; Zhao, D | 1 |
| Henretig, FM; Jew, R; Mechem, C | 1 |
| Bowls, BJ; Freeman, JM; Luna, JA; Meggs, WJ | 1 |
| Agostini, M; Bianchin, A | 1 |
| Breton, P; Buée, J; Calvet, JH; Christin, D; Delamanche, S; Taysse, L | 1 |
| Kassa, J; Krejèová, G | 1 |
| Namera, A | 1 |
| Baskin, SI; Cheng, TC; Hong, K; Jaszberenyi, JC; Jiang, J; Logue, BA; McGuinn, WD; Papahadjopoulos, D; Petrikovics, I; Szilasi, M; Way, JL | 1 |
| ASKEW, BM | 1 |
| HOBBIGER, F | 1 |
| DAVIES, DR; GREEN, AL; WILLEY, GL | 1 |
| BERRY, WK; DAVIES, DR; GREEN, AL | 1 |
| HOBBIGER, F; SADLER, PW | 1 |
| COLBOURN, JL; CROOK, JW; GOODMAN, AI; OBERST, FW | 1 |
| SCHAUMANN, W | 1 |
| CROOK, JW; KOON, WS; OBERST, FW | 2 |
| FLEISHER, JH; HARRISON, CS; MICHEL, HO; YATES, L | 1 |
| COLBOURN, JL; CROOK, JW; GOODMAN, AI; OBERST, FW; WILLS, JH; ZVIRBLIS, P | 1 |
| EDERY, H | 1 |
| BINENFELD, Z; VOJVODIC, V | 1 |
| TONG, HS; WAY, JL | 1 |
| DECANDOLE, CA | 1 |
| QUINBY, GE | 1 |
| BYRON, HM; POSNER, I | 1 |
| JAQUES, R | 1 |
| DIPALMA, JR; ZARRO, VJ | 1 |
| LI, KM | 1 |
| RADELEFF, RD; YOUNGER, RL | 1 |
| KAWEL, HG; SCHNEIDER, JA; SCHUCHTER, A | 1 |
| LEHMAN, RA | 1 |
| PAYNE, JR; ROBINSON, BR | 1 |
| HANZAWA, A; OGAMI, O; SANADA, H; SHIRAISHI, S; SUZUKI, N | 1 |
| Bryant, SM; Cumpston, KL; Mycyk, MB | 1 |
| Meggs, WJ | 1 |
| Wood, SP | 1 |
| Benjamin, A; McDonough, JH; McMonagle, JD; Rowland, T; Shih, TM | 1 |
| Newmark, J | 1 |
| Aygun, D | 1 |
| Eser, B; Güven, M; Sungur, M | 1 |
| Altuntaş, F; Eser, B; Güven, M; Sari, I; Sungur, M | 1 |
| Bambery, P; Parthasarathy, S; Ranjit, A; Sharma, N; Singh, S | 1 |
| Abdi, M; Abdollahi, M; Pajoumand, A; Rezaie, A; Shadnia, S | 1 |
| Adheir, FS; Al Omary, IY; Hanssens, Y; Kamha, AA; Zalabany, HA | 1 |
| Buckley, NA; Eddleston, M; Srinivas Rao, Ch; Surender, T; Venkateswarlu, V | 1 |
| Petroianu, GA | 1 |
| Akgun, A; Ergur, BU; Kalkan, S; Kaplan, YC; Kinay, AO; Tuncok, Y | 1 |
| Lynch, M | 1 |
| Sánchez-Fortún, S; Victoria Barahona, M | 1 |
| Kiateboonsri, S; Thithapandha, A; Wananukul, W | 1 |
| Asaeda, G; Bove, J; Cherson, A; Cooper, A; Curran, J; Foltin, G; Gonzalez, D; Kaufman, B; Langsam, Y; Marshall, L; Tunik, M; van Amerongen, R | 1 |
| Abdullat, IM; Battah, AH; Hadidi, KA | 1 |
| Kellar, KJ | 1 |
| Ansarin, K; Ardalan, MR; Ghaffari, AR; Nezami, N; Noshad, H; Safa, J | 1 |
| Hack, JB; Hoffman, RS; Mercurio-Zappala, M; Salvador, A | 1 |
| Aggarwal, P; Bhoi, S; Goel, A; Gupta, V | 1 |
| Joshi, R; Kalantri, SP | 1 |
| Abroug, F | 1 |
| Kirk, MA; Lawrence, DT | 1 |
| Baker, MD | 1 |
| Bhalla, A; Bhardwaj, U; Gill, K; Singh, S; Verma, SK | 1 |
| Barahona, MV; Sánchez-Fortún, S | 1 |
| Hrobak, PK | 1 |
| Koplovitz, I; Maxwell, DM; Sweeney, RE; Worek, F | 1 |
| Iseki, K | 1 |
| Chan, HM; Chang, JS; Chase, JS; Deng, JF; Denninghoff, K; Hu, SC; Hung, DZ; Lin, TJ; Tsai, JL; Walter, FG | 1 |
| Abbara, C; Bardot, I; Cailleux, A; Clair, P; Diquet, B; Lallement, G; Le Bouil, A; Turcant, A | 1 |
| Oode, Y; Sumi, Y; Tanaka, H | 1 |
| Buckley, N; Davies, J; Eddleston, M; Eyer, P; Roberts, D | 1 |
| Bretholz, A; Hoffman, RS; Morrisey, R | 1 |
| Cevik, Y; Durukan, P; Kavalci, C; Kavalci, G; Ozer, M | 1 |
| Demiryurek, AT; Gunay, N; Kose, A; Sari, I; Tarakcioglu, M; Yildirim, C | 1 |
| Barr, D; Chang, A; Geller, R; Montesano, MA; Thomas, J | 1 |
| Alder, N; Azher, S; Buckley, NA; Dawson, AH; Eddleston, M; Eyer, P; Hittarage, A; Jayamanne, S; Jeganathan, K; Juszczak, E; Mohamed, F; Senarathna, L; Sheriff, MH; von Meyer, L; Worek, F | 1 |
| Clark, MG; Finneran, K; Hilmas, CJ; Poole, MJ; Williams, PT | 1 |
| McDonough, JH; O'Donnell, JC; Shih, TM; Skovira, JW | 1 |
| Abbara, C; Bardot, I; Clair, P; Comets, E; Diquet, B; Lallement, G; Rousseau, JM; Turcant, A | 1 |
| Felberbaum, M; Hoffman, RS; Manini, AF; Mercurio-Zappala, M; Russell-Haders, AL | 1 |
| Demiryurek, AT; Gunay, N; Kose, A; Tarakcioglu, M; Togun, N | 1 |
| Azher, S; Buckley, NA; Eddleston, M; Eyer, P; Moffatt, A; Mohammed, F | 1 |
| Jayapandian, P; Rajasekaran, D; Subbaraghavalu, G | 1 |
| Jajoo, M; Pandey, M; Saxena, S | 1 |
| Abbara, C; Bardot, I; Diquet, B; Ferec, S; Lallement, G; Lelièvre, B; Rousseau, JM; Turcant, A | 1 |
| Kawamata, M; Kawamata, T; Narimatsu, E; Niiya, T; Yamakage, M | 1 |
| Abdollahi, M; Baeeri, M; Karimi, G; Mohammadi, H; Nikfar, S; Sabzevari, O; Shafiee, H | 1 |
| Baccaro, F; Framarini, S; Rovasio, L | 1 |
| Arbelot, C; Boroli, F; Fournier, E; Megarbane, B; Moesch, C; Rouby, JJ; Saleh, M; Soummer, A | 1 |
| Carrasco, M; Cuadrado, BL; Eterović, VA; Ferchmin, PA; Martins, AH; Pérez, D | 2 |
| Ghosh, S; Kundu, AK; Maisnam, I; Maity, A; Saha, SP; Tanima, D | 1 |
| Dillman, JF; Lumley, LA; Meyerhoff, JL; Robison, CL; Spradling, KD | 1 |
| Auta, J; Brown, A; Doctor, BP; Guiodotti, A; Jensen, N; Nambiar, MP; Oguntayo, S; Wang, Y; Wei, Y; Wood, E | 1 |
| Beigi, MJ; Pazooki, S; Shadnia, S; Solhi, H; Vishteh, HR | 1 |
| Jacob, J; Tarabar, AF | 1 |
| Batra, B; Gogia, AR; Pramanik, V; Verma, PK | 1 |
| Can, I; Gul, EE; Kusumoto, FM | 1 |
| Blain, PG; Clutton, RE; Dunn, M; Eddleston, M; Jefferson, RD; Murray, DB; Thomas, S; Thompson, A; Vidler, DS | 1 |
| Gerszten, RE; Jin, S; Jin, YN; Kokel, D; Liu, Y; Macrae, CA; Peterson, RT; Roberts, LD; Sarkar, KS; Van Ham, TJ | 1 |
| Kutti, SK; Mathew, A; Parvez, Y | 1 |
| Ak, A; Bayir, A; Kara, H; Kocabas, R; Köylü, O | 1 |
| Prakash, P; Subbiah, S; Sundaram, M; Swaminathan, K | 1 |
| Arif, SM; Basher, A; Dawson, AH; Faiz, MA; Ghose, A; Rahman, SH | 1 |
| D'Haenens, JP; Farquhar, PN; Higgins, SA; Langley, RL; McDonald, KW; Meggs, WJ; Scott, R | 1 |
| Hu, J; Tang, X; Wang, R; Xie, H; Zhao, W | 1 |
| Antonijević, B; Bošković, B; Ćurčić, M; Vučinić, S; Zlatković, M | 1 |
| Chen, B; Chen, K; Chen, QF; Ruan, HL; Wang, W; Wen, JM | 1 |
| Blair, RE; Carter, DS; DeLorenzo, RJ; Deshpande, LS; Phillips, KF | 1 |
| Cheon, YJ; Choi, YH; Jung, KY; Lee, DH | 1 |
| DeLorenzo, RJ; Deshpande, LS; Huang, B; Phillips, K | 1 |
| Acharya, J; Jatav, PC; Karade, HN; Kumar, A; Kumar, P; Meena, MK; Swami, D | 1 |
| Asghar, A; Mahar, SA; Nakeer, R; Sarfaraz, A; Shahid, M | 1 |
| Chun, B; Moon, J; Song, K | 1 |
| Brewer, KL; Meggs, WJ; Tran, T | 1 |
| Altiti, M; Balkaya, S; Bursal Duramaz, B; Ersoy, M; Kihtir, HS; Petmezci, MT; Sevketoglu, E; Yesilbas, O | 1 |
| Agarwal, R; Behera, D; Dhooria, S | 1 |
| Liu, CF; Liu, HX; Yang, WH | 1 |
| Gao, D; Jian, X; Sun, B; Xiao, L; Yang, L; Zhao, B; Zou, X | 1 |
| Babin, MC; Brittain, MK; Jett, DA; McGarry, KG; Moyer, RA; Platoff, GE; Yeung, DT | 1 |
| Babin, MC; Jett, DA; Platoff, GE; Snider, TH; Yeung, DT | 1 |
| Bealer, SL; Dudek, FE; Pouliot, W; Roach, B | 1 |
| Bao, HX; Chen, BY; Du, J; Huang, ZH; Li, CX; Tong, PJ; Wang, Y | 1 |
| Farzaneh, E; Mostafazadeh, B; Nikkhah, F; Paeezi, M | 1 |
| Çağ, Y; Özçetin, M; Yıldızdaş, D; Yılmaz, HL; Yükselmiş, U | 1 |
| Marques, GLM; Minassa, VS; Pelição, FS; Peres, MD; Sampaio, KN; Siqueira, AA | 1 |
| Chowdhury, M; Das, JC; Faisal, MA; Hasan, SH; Khyrunnessa, F; Muhuri, BR; Paul, N; Paul, S; Sharma, JD; Sharmin, T | 1 |
| Al-Saud, AA; Alaska, YA; Almas, A; Malabaey, MAT; Malik, A | 1 |
| Basrai, Z; Celedon, M; Koh, C; Warren, J | 1 |
| Beijamini, V; Cavadino, A; Dos Santos, L; Felippe, ISA; Müller, CJT; Paton, JFR; Sampaio, KN; Siqueira, AA | 1 |
| Harada, K; Inoue, H; Kakizaki, R; Kyan, R; Narimatsu, E; Nomura, K; Sawamoto, K; Uemura, S | 1 |
| Chan, MJ; Chen, CY; Fu, JF; Hou, YC; Hsu, CW; Huang, WH; Wang, IK; Weng, CH; Yang, HY; Yen, TH; Yu, JR | 1 |
| Cornelissen, AS; Garcia, EE; Joosen, MJA; Laney, J; Raulli, RE | 1 |
| Huang, C; Liu, J; Wang, Y; Yang, Y; Zhang, L; Zhao, D; Zhong, Y; Zhou, Y | 1 |
| Clayman, CL; Ehinger, JK; Elmér, E; Hansson, MJ; Jang, DH; Janowska, JI; Jose, JS; Karlsson, M; Kilbaugh, TJ; McManus, MJ; Piel, S; Sheldon, M; Starr, J; Ward, JL | 1 |
| Narimatsu, E; Nomura, K; Oke, Y; Oku, Y | 1 |
11 review(s) available for atropine and pralidoxime
| Article | Year |
|---|---|
The intermediate syndrome in organophosphate poisoning: presentation of a case and review of the literature.
Topics: Adult; Antidotes; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Dimethoate; Electromyography; Female; Humans; Neuromuscular Diseases; Pralidoxime Compounds; Respiratory Paralysis; Synaptic Transmission; Syndrome; Ventilators, Mechanical | 1992 |
Management of acute childhood poisonings caused by selected insecticides and herbicides.
Topics: Absorption; Adolescent; Animals; Anticonvulsants; Atropine; Carbamates; Central Nervous System; Child; Child, Preschool; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Gastric Lavage; Herbicides; Humans; Insecticides; Nausea; Organophosphorus Compounds; Paraquat; Pralidoxime Compounds; Seizures; Vomiting | 1986 |
Effects of atropine sulfate and pralidoxime chloride on visual, physiological, performance, subjective, and cognitive variables in man: a review.
Topics: Atropine; Cognition; Humans; Physical Exertion; Pralidoxime Compounds; Vision, Ocular | 1982 |
Cholinesterase-inhibiting insecticide toxicity.
Topics: Antidotes; Atropine; Cholinesterase Inhibitors; Cholinesterases; Environmental Monitoring; Epidemiological Monitoring; Erythrocyte Count; Humans; Insecticides; Occupational Exposure; Poisoning; Pralidoxime Compounds; Risk Factors | 1993 |
Oximes in acute organophosphorus pesticide poisoning: a systematic review of clinical trials.
Topics: Acute Disease; Atropine; Drug Overdose; Humans; Insecticides; Organophosphorus Compounds; Oximes; Pralidoxime Compounds; Randomized Controlled Trials as Topic; Research Design | 2002 |
[Practical analysis of toxic substances useful for clinical toxicology--6--Organophosphates].
Topics: Atropine; Cholinesterase Reactivators; Chromatography, Thin Layer; Female; Fenitrothion; Gas Chromatography-Mass Spectrometry; Humans; Insecticides; Malathion; Middle Aged; Muscarinic Antagonists; Pralidoxime Compounds | 2003 |
Therapy for nerve agent poisoning.
Topics: Antidotes; Atropine; Chemical Warfare Agents; Humans; Neurotoxicity Syndromes; Neurotoxins; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Pralidoxime Compounds; Pyridostigmine Bromide; Sarin; Soman | 2004 |
Diagnosis in an acute organophosphate poisoning: report of three interesting cases and review of the literature.
Topics: Acetylcholinesterase; Acute Disease; Adult; Aged; Antidotes; Atropine; Emergency Medicine; Female; Humans; Insecticides; Male; Organophosphorus Compounds; Poisoning; Pralidoxime Compounds; Treatment Outcome | 2004 |
Chemical terrorism attacks: update on antidotes.
Topics: Antidotes; Atropine; Botulinum Toxins; Chemical Terrorism; Humans; Muscarinic Antagonists; Potassium Iodide; Pralidoxime Compounds; Radiation Injuries | 2007 |
Antidotes for nerve agent poisoning: should we differentiate children from adults?
Topics: Adult; Antidotes; Atropine; Chemical Warfare Agents; Child; Humans; Organophosphate Poisoning; Pralidoxime Compounds | 2007 |
[Antidose therapy for organophosphate poisoning].
Topics: Antidotes; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Humans; Organophosphate Poisoning; Pesticides; Pralidoxime Compounds | 2008 |
13 trial(s) available for atropine and pralidoxime
| Article | Year |
|---|---|
Does pralidoxime affect outcome of management in acute organophosphorus poisoning?
Topics: Adolescent; Adult; Aged; Atropine; Cholinesterase Reactivators; Critical Care; Drug Therapy, Combination; Female; Humans; Length of Stay; Male; Middle Aged; Organophosphate Poisoning; Poisoning; Pralidoxime Compounds; Sri Lanka; Treatment Outcome; Ventilators, Mechanical | 1992 |
Effects of nerve agent antidote and heat exposure on soldier performance in the BDU and MOPP-IV ensembles.
Topics: Adolescent; Adult; Affect; Antidotes; Atropine; Drug Therapy, Combination; Efficiency; Heat Exhaustion; Humans; Male; Military Personnel; Pralidoxime Compounds; Protective Clothing | 1990 |
Effects of atropine and 2-PAM chloride on vision and performance in humans.
Topics: Accommodation, Ocular; Adult; Atropine; Blood Pressure; Color Perception; Double-Blind Method; Emotions; Humans; Male; Pralidoxime Compounds; Psychomotor Performance; Pulse; Pupil; Vision, Ocular; Visual Acuity | 1987 |
The effects of fresh frozen plasma on cholinesterase levels and outcomes in patients with organophosphate poisoning.
Topics: Atropine; Butyrylcholinesterase; Cholinesterase Reactivators; Humans; Length of Stay; Muscarinic Antagonists; Organophosphate Poisoning; Plasma; Pralidoxime Compounds; Prospective Studies; Treatment Outcome | 2004 |
Benefits of magnesium sulfate in the management of acute human poisoning by organophosphorus insecticides.
Topics: Adolescent; Adult; Aged; Atropine; Cholinesterase Reactivators; Drug Therapy, Combination; Female; Humans; Insecticides; Magnesium Sulfate; Male; Middle Aged; Muscarinic Antagonists; Obidoxime Chloride; Organophosphate Poisoning; Organophosphates; Pralidoxime Compounds; Single-Blind Method | 2004 |
Pralidoxime in acute organophosphorus insecticide poisoning--a randomised controlled trial.
Topics: Acetylcholinesterase; Adult; Antidotes; Atropine; Drug Therapy, Combination; Female; Humans; Insecticides; Intubation, Intratracheal; Male; Organoplatinum Compounds; Poisoning; Pralidoxime Compounds | 2009 |
Bioavailability of diazepam after intramuscular injection of its water-soluble prodrug alone or with atropine-pralidoxime in healthy volunteers.
Topics: Adolescent; Adult; Area Under Curve; Atropine; Biological Availability; Chromatography, High Pressure Liquid; Cross-Over Studies; Diazepam; Dipeptides; Drug Combinations; Humans; Injections, Intramuscular; Male; Middle Aged; Pralidoxime Compounds; Prodrugs; Solubility; Tandem Mass Spectrometry; Water | 2009 |
Pharmacokinetic analysis of pralidoxime after its intramuscular injection alone or in combination with atropine-avizafone in healthy volunteers.
Topics: Adolescent; Adult; Atropine; Dipeptides; Drug Combinations; Drug Interactions; Humans; Injections, Intramuscular; Male; Middle Aged; Models, Statistical; Pralidoxime Compounds | 2010 |
Effectiveness of fresh frozen plasma as supplementary treatment in organophosphate poisoning.
Topics: Adult; Atropine; Female; Humans; Male; Middle Aged; Organophosphate Poisoning; Plasma; Pralidoxime Compounds | 2011 |
Phase II study of magnesium sulfate in acute organophosphate pesticide poisoning.
Topics: Acute Disease; Adolescent; Adult; Atropine; Bangladesh; Cholinesterase Reactivators; Dose-Response Relationship, Drug; Female; Hospitals, University; Humans; Infusions, Intravenous; Magnesium; Magnesium Sulfate; Male; Middle Aged; Muscarinic Antagonists; Organophosphate Poisoning; Pralidoxime Compounds; Severity of Illness Index; Young Adult | 2013 |
Clinical study of continuous micropump infusion of atropine and pralidoxime chloride for treatment of severe acute organophosphorus insecticide poisoning.
Topics: Adult; Atropine; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Insecticides; Male; Organophosphate Poisoning; Pralidoxime Compounds | 2015 |
[The influence of sodium bicarbonate combined with ulinastatin on cholinesterase activity for patients with acute phoxim pesticide poisoning].
Topics: Atropine; Cholinesterases; Glycoproteins; Humans; Organophosphate Poisoning; Organothiophosphorus Compounds; Pesticides; Pralidoxime Compounds; Sodium Bicarbonate | 2016 |
Efficacy of fresh packed red blood transfusion in organophosphate poisoning.
Topics: Acute Disease; Atropine; Cholinesterase Reactivators; Cholinesterases; Erythrocyte Transfusion; Female; Gastric Lavage; Humans; Male; Organophosphate Poisoning; Pralidoxime Compounds; Prospective Studies; Time Factors | 2017 |
201 other study(ies) available for atropine and pralidoxime
| Article | Year |
|---|---|
Clinical, biochemical, electrophysiologic, and histologic assessment of chlorpyrifos induced delayed neuropathy in the cat.
Topics: Animals; Antidotes; Atropine; Carboxylic Ester Hydrolases; Cats; Chlorpyrifos; Cholinesterases; Diazepam; Electromyography; Isoflurophate; Lymphocytes; Male; Motor Neurons; Nervous System Diseases; Neural Conduction; Pralidoxime Compounds; Time Factors | 1992 |
Evaluation of the toxicity, pathology, and treatment of cyclohexylmethylphosphonofluoridate (CMPF) poisoning in rhesus monkeys.
Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Lethal Dose 50; Macaca mulatta; Male; Organophosphate Poisoning; Organophosphorus Compounds; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Pyridostigmine Bromide | 1992 |
Effects of oximes and atropine on acute phosphamidon intoxication in Bubalus bubalis.
Topics: Animals; Antidotes; Atropine; Buffaloes; Cholinesterase Reactivators; Diacetyl; Drug Combinations; Fasciculation; Male; Phosphamidon; Pralidoxime Compounds; Sialorrhea; Tremor | 1992 |
Prolonged toxicity with intermediate syndrome after combined parathion and methyl parathion poisoning.
Topics: Adult; Antidotes; Atropine; Butyrylcholinesterase; Cholinesterase Inhibitors; Cholinesterase Reactivators; Cholinesterases; Electromyography; Erythrocytes; Female; Humans; Male; Methyl Parathion; Middle Aged; Neuromuscular Diseases; Parathion; Pralidoxime Compounds; Respiratory Paralysis | 1992 |
Efficacy of various oximes against GF (cyclohexyl methylphosphonofluoridate) poisoning in mice.
Topics: Animals; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Reactivators; In Vitro Techniques; Lethal Dose 50; Male; Mice; Mice, Inbred Strains; Nervous System Diseases; Obidoxime Chloride; Organophosphate Poisoning; Organophosphorus Compounds; Oximes; Pralidoxime Compounds; Pyridinium Compounds | 1992 |
Endosulfan poisoning: a study of 22 cases.
Topics: Adult; Antidotes; Atropine; Cholinesterase Reactivators; Endosulfan; Humans; Male; Poisoning; Pralidoxime Compounds | 1992 |
Waivers for military use of investigational agents.
Topics: Antidotes; Atropine; Botulinum Antitoxin; Drugs, Investigational; Ethics, Pharmacy; Federal Government; Government Regulation; Gulf War; Human Experimentation; Humans; Informed Consent; Military Personnel; Pralidoxime Compounds; Pyridostigmine Bromide; Risk Assessment; Saudi Arabia; United States; Warfare | 1991 |
Protection from lethality and behavioral incapacitation resulting from intoxication by soman (pinacolyl methylphosphonofluoridate) and treatment with atropine sulfate and 2-PAM chloride in the guinea pig, cavia porcellus.
Topics: Animals; Atropine; Avoidance Learning; Cholinesterase Reactivators; Drug Therapy, Combination; Guinea Pigs; Lethal Dose 50; Male; Pralidoxime Compounds; Soman | 1991 |
A comparison of cholinergic effects of HI-6 and pralidoxime-2-chloride (2-PAM) in soman poisoning.
Topics: Acetylcholinesterase; Animals; Atropine; Brain; Cholinesterase Reactivators; Cholinesterases; Drug Interactions; Lethal Dose 50; Male; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Soman | 1991 |
Variable effects of soman on macromolecular secretion by ferret trachea.
Topics: Acetylcholine; Animals; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Ferrets; L-Lactate Dehydrogenase; Male; Organ Culture Techniques; Pralidoxime Compounds; Soman; Sulfates; Sulfur Radioisotopes; Trachea | 1991 |
Evaluation of phosphinates as potential pretreatments for nerve agents.
Topics: Acetylcholinesterase; Animals; Atropine; Cholinesterase Reactivators; Evaluation Studies as Topic; Guinea Pigs; Injections, Intramuscular; Lethal Dose 50; Male; Nitrobenzenes; Organophosphorus Compounds; Oximes; Pralidoxime Compounds; Pyridinium Compounds | 1991 |
Heat exchange after cholinolytic and oxime therapy in protective clothing.
Topics: Adult; Atropine; Body Temperature Regulation; Cholinesterase Reactivators; Hot Temperature; Humans; Male; Pralidoxime Compounds; Protective Clothing; Stress, Physiological | 1990 |
High dose atropine in organophosphorus poisoning.
Topics: Antidotes; Atropine; Cholinesterase Reactivators; Drug Administration Schedule; Humans; Insecticides; Organophosphorus Compounds; Pralidoxime Compounds; Time Factors | 1990 |
Prevention and treatment of nerve gas poisoning.
Topics: Animals; Anticonvulsants; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Gas Poisoning; Humans; Pralidoxime Compounds; Protective Clothing; Pyridostigmine Bromide; Respiratory Protective Devices | 1990 |
Receptor-mediated presynaptic facilitation of quantal release of acetylcholine induced by pralidoxime in Aplysia.
Topics: Acetylcholine; Acetylcholinesterase; Action Potentials; Animals; Aplysia; Atropine; Enzyme Activation; Hemicholinium 3; Neurons; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Receptors, Nicotinic; Secretory Rate; Synapses; Tubocurarine | 1990 |
Prompt recovery from severe cholinesterase-inhibitor poisoning--remarks on classification and therapy of organophosphate poisoning.
Topics: Acetylcholinesterase; Adult; Aged; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Combined Modality Therapy; Drug Overdose; Erythrocytes; Female; Fenthion; Gastric Lavage; Humans; Insecticides; Male; Middle Aged; Neurologic Examination; Parathion; Pralidoxime Compounds | 1990 |
Effects of atropine/2-PAM chloride, heat, and chemical protective clothing on visual performance.
Topics: Adolescent; Adult; Antidotes; Atropine; Chemical Warfare; Contrast Sensitivity; Depth Perception; Gas Poisoning; Hot Temperature; Humans; Humidity; Male; Pralidoxime Compounds; Protective Clothing; Time Factors; Vision, Ocular; Visual Acuity | 1990 |
Respiratory failure of acute organophosphate and carbamate poisoning.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antidotes; Atropine; Carbamates; Child; Child, Preschool; Female; Humans; Infant; Insecticides; Male; Middle Aged; Organophosphorus Compounds; Pneumonia; Pralidoxime Compounds; Respiration, Artificial; Respiratory Insufficiency | 1990 |
The relationship between oxime-induced reactivation of carbamylated acetylcholinesterase and antidotal efficacy against carbamate intoxication.
Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Carbaryl; Cholinesterase Inhibitors; Cholinesterase Reactivators; Drug Interactions; Erythrocytes; Lethal Dose 50; Male; Oximes; Physostigmine; Pralidoxime Compounds; Pyridinium Compounds; Rats; Rats, Inbred Strains | 1989 |
Effects of soman and its antidotes on tracheal mucociliary transport of ferrets.
Topics: Animals; Atropine; Blood Pressure; Carbon Dioxide; Cholinesterase Reactivators; Ferrets; Heart Rate; Hydrogen-Ion Concentration; Male; Mucociliary Clearance; Oxygen; Partial Pressure; Pralidoxime Compounds; Reference Values; Soman; Trachea | 1989 |
Cold exposure decreases the effectiveness of atropine-oxime treatment in organophosphate intoxication in rats and mice.
Topics: Animals; Antidotes; Atropine; Carboxylic Ester Hydrolases; Cholinesterase Reactivators; Cold Temperature; Enzyme Reactivators; Isoflurophate; Lethal Dose 50; Mice; Obidoxime Chloride; Organophosphate Poisoning; Oximes; Pralidoxime Compounds; Rats; Rats, Inbred F344 | 1989 |
An insect bioassay as a primary screen for nerve agent antidotes.
Topics: Animals; Antidotes; Atropine; Biological Assay; Cholinesterase Reactivators; Female; Houseflies; Isoflurophate; Nervous System; Physostigmine; Pralidoxime Compounds | 1986 |
Effects of atropine, 2-PAM, or pyridostigmine in euvolemic or hemorrhagic conscious swine.
Topics: Acetylcholinesterase; Animals; Atropine; Blood Pressure; Erythrocytes; Heart Rate; Injections, Intra-Arterial; Pralidoxime Compounds; Pyridostigmine Bromide; Shock, Hemorrhagic; Swine | 1988 |
Combined atropine and 2-PAM Cl effects on tracking performance and visual, physiological, and psychological functions.
Topics: Accommodation, Ocular; Adult; Arousal; Atropine; Cholinesterase Reactivators; Color Perception; Depth Perception; Dose-Response Relationship, Drug; Drug Synergism; Eye Movements; Humans; Male; Mental Recall; Pralidoxime Compounds; Psychological Tests; Psychomotor Performance; Pursuit, Smooth; Sensation; Visual Acuity | 1988 |
In vivo protection against soman toxicity by known inhibitors of acetylcholine synthesis in vitro.
Topics: Acetylcholine; Animals; Atropine; Cholinesterase Reactivators; Hemicholinium 3; Kinetics; Lethal Dose 50; Male; Pralidoxime Compounds; Rats; Rats, Inbred Strains; Soman; Structure-Activity Relationship | 1988 |
Prolonged organophosphate toxicity in a twenty-six-month-old child.
Topics: Accidents; Atropine; Child, Preschool; Drug Therapy, Combination; Fenthion; Humans; Male; Muscle Tonus; Organophosphate Poisoning; Pesticides; Pralidoxime Compounds; Respiration; Respiration, Artificial | 1988 |
Carbamate poisoning: the 'other' insecticide.
Topics: Antidotes; Atropine; Carbamates; Female; Humans; Infant; Insecticides; Organophosphorus Compounds; Pralidoxime Compounds; Vitamin K | 1987 |
Effects of cholinesterase reactivators and atropine on fenitrothion-induced hypothermia in Bubalus bubalis.
Topics: Acetylcholinesterase; Animals; Atropine; Body Temperature; Buffaloes; Butanones; Cholinesterase Reactivators; Diacetyl; Erythrocytes; Fenitrothion; Hypothermia; Pralidoxime Compounds | 1987 |
Human thermoregulation after atropine and/or pralidoxime administration.
Topics: Adult; Atropine; Body Temperature Regulation; Humans; Male; Physical Exertion; Plethysmography; Pralidoxime Compounds; Regional Blood Flow; Skin; Sweating | 1987 |
Percutaneous organophosphate poisoning.
Topics: Atropine; Coma; Diazinon; Humans; Insecticides; Lice Infestations; Male; Middle Aged; Pralidoxime Compounds; Seizures; Self Medication; Skin Absorption | 1987 |
Protective effects of oximes HI-6 and PAM-2 applied by osmotic minipumps in quinalphos-poisoned rats.
Topics: Animals; Antidotes; Atropine; Brain; Cholinesterase Reactivators; Cholinesterases; Diazepam; Insecticides; Lethal Dose 50; Male; Muscles; Organothiophosphorus Compounds; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Rats | 1987 |
Protection by phenytoin and calcium channel blocking agents against the toxicity of diisopropylfluorophosphate.
Topics: Animals; Anticonvulsants; Atropine; Calcium Channel Blockers; Isoflurophate; Lethal Dose 50; Male; Mice; Phenytoin; Pralidoxime Compounds | 1986 |
Oxime-induced decarbamylation and atropine/oxime therapy of guinea pigs intoxicated with pyridostigmine.
Topics: Acetylcholinesterase; Animals; Atropine; Erythrocytes; Guinea Pigs; Male; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Pyridostigmine Bromide | 1987 |
Organophosphate insecticide poisoning.
Topics: Acute Disease; Adult; Atropine; Cholinesterase Reactivators; Critical Care; Humans; Insecticides; Male; Organophosphate Poisoning; Organothiophosphates; Organothiophosphorus Compounds; Pralidoxime Compounds | 1985 |
Relationship between reversible acetylcholinesterase inhibition and efficacy against soman lethality.
Topics: Acetylcholinesterase; Animals; Atropine; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Guinea Pigs; Male; Mecamylamine; Organophosphorus Compounds; Physostigmine; Pralidoxime Compounds; Pyridostigmine Bromide; Rats; Soman | 1985 |
Atropine sulfate and 2-pyridine aldoxime methylchloride elicit stress-induced convulsions and lethality in mice and guinea pigs.
Topics: Animals; Atropine; Blood Glucose; Body Temperature; Cold Temperature; Diazepam; Drug Interactions; Guinea Pigs; Male; Mice; Mice, Inbred ICR; Pralidoxime Compounds; Seizures; Species Specificity; Stress, Physiological; Swimming; Time Factors | 1985 |
Efficacy and toxicity of drug combinations in treatment of physostigmine toxicosis.
Topics: Animals; Atropine; Benactyzine; Cholinesterase Reactivators; Diazepam; Drug Therapy, Combination; Ganglionic Blockers; Hexamethonium; Hexamethonium Compounds; Male; Mecamylamine; Mice; Physostigmine; Pralidoxime Compounds; Tranquilizing Agents; Trimedoxime | 1983 |
Brain neuronal RNA metabolism during acute soman toxication: effects of antidotal pretreatments.
Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Brain; Caudate Nucleus; Cerebral Cortex; Cholinesterase Inhibitors; Cholinesterase Reactivators; Male; Neurons; Organophosphorus Compounds; Physostigmine; Pralidoxime Compounds; Rats; Rats, Inbred Strains; RNA; Soman | 1983 |
Antidotes and neuropathic potential of isofenphos.
Topics: Animals; Antidotes; Atropine; Carboxylic Ester Hydrolases; Chickens; Dose-Response Relationship, Drug; Female; Insecticides; Lethal Dose 50; Male; Nervous System Diseases; Organothiophosphorus Compounds; Pralidoxime Compounds; Rats; Rats, Inbred Strains | 1984 |
Effect of PAM-2 Cl, HI-6, and HGG-12 in poisoning by tabun and its thiocholine-like analog in the rat.
Topics: Animals; Atropine; Choline; Cholinesterase Reactivators; Cholinesterases; Female; Guinea Pigs; Heart; Humans; Lethal Dose 50; Male; Muscle Contraction; Muscle, Smooth; Organophosphate Poisoning; Organophosphates; Oximes; Phrenic Nerve; Pralidoxime Compounds; Pyridinium Compounds; Rats; Thiocholine | 1984 |
Differential effects of di-isopropylfluorophosphate poisoning and its treatment on opioid antinociception in the mouse.
Topics: Animals; Atropine; Cholinesterase Reactivators; Isoflurophate; Male; Mice; Narcotics; Nociceptors; Pain; Pralidoxime Compounds | 1983 |
PAM-2 Cl, HI-6, and HGG-12 in soman and tabun poisoning.
Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diazepam; Dogs; Guinea Pigs; Lethal Dose 50; Male; Mice; Organophosphate Poisoning; Organophosphates; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Rats; Soman; Species Specificity | 1984 |
Two unusual presentations of organophosphate poisoning.
Topics: Aged; Atropine; Cholinesterase Reactivators; Cholinesterases; Erythrocytes; Humans; Male; Middle Aged; Organophosphate Poisoning; Pralidoxime Compounds | 1982 |
[Poisoning by organo-phosphorate compounds (author's transl)].
Topics: Adult; Atropine; Cholinesterase Inhibitors; Female; Humans; Insecticides; Male; Organophosphorus Compounds; Pralidoxime Compounds; Respiration, Artificial | 1981 |
Antidotal action of atropine sulfate against insecticide benfuracarb poisoning in rats.
Topics: Administration, Oral; Animals; Antidotes; Atropine; Benzofurans; beta-Alanine; Carbamates; Cholinesterase Reactivators; Injections, Intraperitoneal; Insecticides; Male; Pralidoxime Compounds; Rats; Rats, Sprague-Dawley | 1995 |
Acute toxicity of cyclohexylmethylphosphonofluoridate (CMPF) in rhesus monkeys: serum biochemical and hematologic changes.
Topics: Alanine Transaminase; Animals; Antidotes; Aspartate Aminotransferases; Atropine; Biomarkers; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Creatine Kinase; Injections, Intramuscular; L-Lactate Dehydrogenase; Lethal Dose 50; Macaca mulatta; Male; Organophosphorus Compounds; Oximes; Potassium; Pralidoxime Compounds; Pyridinium Compounds; Pyridostigmine Bromide; Seizures | 1995 |
Reflex sympathetic dystrophy syndrome secondary to organophosphate intoxication induced neuropathy.
Topics: Action Potentials; Adult; Atropine; Bone and Bones; Calcitonin; Cholinesterase Reactivators; Dimethoate; Electromyography; Follow-Up Studies; Humans; Male; Median Nerve; Motor Neurons; Muscle, Skeletal; Nervous System Diseases; Pralidoxime Compounds; Radiography; Radionuclide Imaging; Reflex Sympathetic Dystrophy; Ulnar Nerve | 1994 |
Treatment of nerve gas poisoning.
Topics: Anticonvulsants; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Gases; Humans; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Pralidoxime Compounds; Pyridostigmine Bromide; Respiratory Protective Devices; Sarin; Soman | 1995 |
Emergency care of insecticide poisonings.
Topics: Antidotes; Atropine; Blood Circulation; Carbamates; Cholinesterases; Critical Care; Decontamination; Emergency Medical Services; Emergency Service, Hospital; Humans; Insecticides; Organophosphorus Compounds; Poisoning; Pralidoxime Compounds; Respiration; Treatment Outcome | 1994 |
Primate performance decrements following acute soman exposure: failure of chemical countermeasures.
Topics: Animals; Atropine; Cholinesterase Reactivators; Cholinesterases; Dose-Response Relationship, Drug; Macaca mulatta; Male; Pralidoxime Compounds; Psychomotor Performance; Pyridostigmine Bromide; Soman | 1994 |
Percutaneous exposure to ethyl parathion in a feral Griffon vulture (Gyps fulvus).
Topics: Administration, Cutaneous; Animals; Atropine; Bird Diseases; Birds; Fatal Outcome; Paralysis; Parathion; Pralidoxime Compounds | 1994 |
Carbamate poisoning and oxime treatment in children: a clinical and laboratory study.
Topics: Aldicarb; Antidotes; Atropine; Carbamates; Child; Child, Preschool; Cholinesterases; Drug Therapy, Combination; Female; Humans; Infant; Male; Methomyl; Obidoxime Chloride; Oximes; Paraoxon; Poisoning; Pralidoxime Compounds; Retrospective Studies | 1994 |
A comparison of the efficacy of HI6 and 2-PAM against soman, tabun, sarin, and VX in the rabbit.
Topics: Animals; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diazepam; Lethal Dose 50; Male; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Poisoning; Pralidoxime Compounds; Pyridinium Compounds; Pyridostigmine Bromide; Rabbits; Sarin; Soman; Specific Pathogen-Free Organisms | 1994 |
Organophosphate poisoning: peripheral vascular resistance--a measure of adequate atropinization.
Topics: Acetylcholinesterase; Aged; Alprazolam; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Dimethoate; Drug Interactions; Fenthion; Humans; Male; Middle Aged; Poisoning; Pralidoxime Compounds; Vascular Diseases; Vascular Resistance | 1994 |
Sarin induced lung pathology and protection by standard therapy regime.
Topics: Animals; Atropine; Cholinesterase Reactivators; Diazepam; Environmental Exposure; Lung; Male; Pralidoxime Compounds; Rats; Sarin | 1993 |
Quaternary salts of 3,3'-bis-pyridinium monooximes: synthesis and biological activity.
Topics: Animals; Antidotes; Atropine; Cholinesterase Reactivators; Isoflurophate; Kinetics; Magnetic Resonance Spectroscopy; Mice; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Spectrophotometry, Infrared; Structure-Activity Relationship; Trimedoxime | 1993 |
Pharmacological dissociation of the motor and electrical aspects of convulsive status epilepticus induced by the cholinesterase inhibitor soman.
Topics: Analysis of Variance; Animals; Antidotes; Atropine; Brain; Cholinesterase Inhibitors; Diazepam; Electroencephalography; Guinea Pigs; Image Processing, Computer-Assisted; Male; Pralidoxime Compounds; Pyridostigmine Bromide; Scopolamine; Soman; Status Epilepticus | 1993 |
Neuroleptic malignant-like syndrome: a complication of acute organophosphate poisoning.
Topics: Atropine; Cholinesterase Reactivators; Cholinesterases; Dantrolene; Female; Humans; Middle Aged; Miosis; Muscarinic Antagonists; Muscle Relaxants, Central; Neuroleptic Malignant Syndrome; Organophosphate Poisoning; Organothiophosphorus Compounds; Poisoning; Pralidoxime Compounds; Respiration; Salivation; Schizophrenia; Seizures; Suicide, Attempted; Therapeutic Irrigation | 1995 |
A comparison of trimedoxime, obidoxime, pralidoxime and HI-6 in the treatment of oral organophosphorus insecticide poisoning in the rat.
Topics: Administration, Oral; Animals; Antidotes; Atropine; Diazepam; Dose-Response Relationship, Drug; Insecticides; Male; Obidoxime Chloride; Organophosphorus Compounds; Oximes; Pralidoxime Compounds; Rats; Rats, Wistar; Trimedoxime | 1995 |
Antagonism of the lethal effects of paraoxon by carrier erythrocytes containing phosphotriesterase.
Topics: Animals; Antidotes; Aryldialkylphosphatase; Atropine; Cholinesterases; Dose-Response Relationship, Drug; Drug Carriers; Drug Combinations; Erythrocytes; Esterases; Insecticides; Male; Mice; Mice, Inbred BALB C; Mortality; Paraoxon; Pralidoxime Compounds; Survival; Time Factors | 1995 |
Acute toxicity of several organophosphorous insecticides and protection by cholinergic antagonists and 2-PAM on Artemia salina larvae.
Topics: Animals; Artemia; Atropine; Chlorpyrifos; Cholinergic Antagonists; Cholinesterase Reactivators; Cysts; Hexamethonium; Insecticides; Larva; Methyl Parathion; Parasympatholytics; Parathion; Pirenzepine; Poisoning; Pralidoxime Compounds; Species Specificity; Structure-Activity Relationship | 1996 |
Efficacy of atropine/pralidoxime/diazepam or atropine/HI-6/prodiazepam in primates intoxicated by soman.
Topics: Animals; Antidotes; Atropine; Cholinesterase Inhibitors; Diazepam; Dipeptides; Drug Therapy, Combination; Electrocardiography; Electroencephalography; Macaca fascicularis; Male; Oximes; Poisoning; Pralidoxime Compounds; Prodrugs; Pyridinium Compounds; Soman | 1997 |
Pralidoxime continuous infusion in the treatment of organophosphate poisoning.
Topics: Adult; Antidotes; Atropine; Chlorpyrifos; Drug Therapy, Combination; Humans; Infusions, Intravenous; Insecticides; Male; Muscarinic Antagonists; Poisoning; Pralidoxime Compounds | 1997 |
Intravenous organophosphate injection: an unusual way of intoxication.
Topics: Adult; Antidotes; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Humans; Injections, Intravenous; Insecticides; Male; Muscarinic Antagonists; Nervous System Diseases; Organothiophosphorus Compounds; Pralidoxime Compounds; Schizophrenia; Suicide, Attempted | 1997 |
Evaluation of combined toxic effects of GB/GF and efficacy of jielin injection against combined poisoning in mice.
Topics: Animals; Antidotes; Atropine; Benactyzine; Chemical Warfare Agents; Cholinesterase Reactivators; Female; Humans; Injections; Male; Mice; Organophosphorus Compounds; Pralidoxime Compounds; Sarin; Software | 1997 |
Poisonings associated with illegal use of aldicarb as a rodenticide -- New York City, 1994-1997.
Topics: Adult; Aldicarb; Anti-Arrhythmia Agents; Atropine; Child, Preschool; Cholinesterase Reactivators; Female; Humans; Insecticides; Male; New York City; Pest Control; Poisoning; Pralidoxime Compounds; Rodenticides | 1997 |
New treatment regimens in organophosphate (diazinon) and carbamate (methomyl) insecticide-induced toxicosis in fowl.
Topics: Animals; Antidotes; Atropine; Chickens; Diazinon; Dose-Response Relationship, Drug; Insecticides; Methomyl; Pralidoxime Compounds | 1997 |
Nerve agent poisoning in primates: antilethal, anti-epileptic and neuroprotective effects of GK-11.
Topics: Animals; Anticonvulsants; Atropine; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Cyclohexanes; Cyclohexenes; Diazepam; Drug Combinations; Excitatory Amino Acid Antagonists; Injections, Intravenous; Macaca fascicularis; Male; Muscarinic Antagonists; Neuroprotective Agents; Piperidines; Pralidoxime Compounds; Seizures; Soman; Staining and Labeling; Time Factors | 1998 |
Clinical and toxicological data in fenthion and omethoate acute poisoning.
Topics: Adult; Antidotes; Atropine; Charcoal; Cholinesterase Inhibitors; Cholinesterase Reactivators; Critical Care; Dimethoate; Female; Fenthion; Gastric Lavage; Greece; Humans; Insecticides; Male; Middle Aged; Poisoning; Pralidoxime Compounds; Treatment Outcome | 1998 |
Intermediate syndrome with delayed distal polyneuropathy from ethyl parathion poisoning.
Topics: Acute Disease; Adult; Atropine; Cholinesterase Reactivators; Drug Overdose; Drug Therapy, Combination; Female; Gastric Lavage; Humans; Insecticides; Muscles; Parathion; Peripheral Nervous System Diseases; Pralidoxime Compounds; Recurrence; Respiration, Artificial; Suicide, Attempted; Syndrome; Treatment Outcome | 1998 |
Acute soman poisoning in primates neither pretreated nor receiving immediate therapy: value of gacyclidine (GK-11) in delayed medical support.
Topics: Animals; Anticonvulsants; Antidotes; Atropine; Brain; Cerebellum; Cerebral Cortex; Chemical Warfare Agents; Cholinesterase Reactivators; Cyclohexanes; Cyclohexenes; Diazepam; Drug Therapy, Combination; Electrocardiography; Excitatory Amino Acid Antagonists; Haplorhini; Macaca fascicularis; Male; Piperidines; Poisoning; Pralidoxime Compounds; Seizures; Soman; Time Factors | 1999 |
[Intermediate syndrome after acute organophosphorus pesticides poisoning: clinical analysis of 10 cases].
Topics: Adult; Antidotes; Atropine; Cholinesterase Reactivators; Deglutition Disorders; Female; Hoarseness; Humans; Insecticides; Male; Middle Aged; Organophosphorus Compounds; Pralidoxime Compounds; Respiration, Artificial; Respiratory Paralysis; Syndrome | 1997 |
Efficacy of biperiden and atropine as anticonvulsant treatment for organophosphorus nerve agent intoxication.
Topics: Animals; Anticonvulsants; Atropine; Biperiden; Cholinesterase Inhibitors; Cholinesterase Reactivators; Disease Models, Animal; Drug Therapy, Combination; Electroencephalography; Guinea Pigs; Lethal Dose 50; Male; Organophosphates; Organophosphorus Compounds; Pralidoxime Compounds; Pyridostigmine Bromide; Sarin; Seizures; Soman | 2000 |
Compared efficacy of diazepam or avizafone to prevent soman-induced electroencephalographic disturbances and neuropathology in primates: relationship to plasmatic benzodiazepine pharmacokinetics.
Topics: Animals; Atropine; Brain; Cholinesterase Inhibitors; Diazepam; Dipeptides; Drug Therapy, Combination; Electroencephalography; Macaca fascicularis; Male; Pralidoxime Compounds; Soman | 2000 |
Aldicarb poisoning.
Topics: Adolescent; Adult; Aged; Aldicarb; Antidotes; Atropine; Child; Child, Preschool; Cholinesterases; Chromatography, High Pressure Liquid; Drug Therapy, Combination; Female; Humans; Infant; Male; Middle Aged; Pesticides; Poisoning; Pralidoxime Compounds; West Indies | 2000 |
The use of carbamates, atropine, and 2-pyridine aldoxime methoiodide in the protection of Artemia salina against poisoning by carbophenothion.
Topics: Animals; Artemia; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Dose-Response Relationship, Drug; Drug Interactions; Insecticides; Lethal Dose 50; Muscarinic Antagonists; Organothiophosphorus Compounds; Physostigmine; Pralidoxime Compounds; Pyridostigmine Bromide; Water Pollutants, Chemical | 2001 |
Aldicarb poisoning by an illicit rodenticide imported into the United States: Tres Pasitos.
Topics: Adolescent; Adult; Aldicarb; Animals; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Chromatography, High Pressure Liquid; Chromatography, Paper; Disease Outbreaks; Gas Chromatography-Mass Spectrometry; Humans; Infant; Male; Mice; New York City; Pralidoxime Compounds; Prospective Studies; Rodenticides; Treatment Outcome | 2001 |
Organophosphate poisoning in children - atropine, pralidoxime or both?
Topics: Antidotes; Atropine; Child, Preschool; Drug Therapy, Combination; Humans; Insecticides; Male; Muscarinic Antagonists; Organophosphate Poisoning; Positive-Pressure Respiration; Pralidoxime Compounds | 2001 |
Cholinesterase inhibition by aluminium phosphide poisoning in rats and effects of atropine and pralidoxime chloride.
Topics: Aluminum Compounds; Animals; Antidotes; Atropine; Blood Pressure; Cholinesterase Inhibitors; Cholinesterase Reactivators; Cholinesterases; Drug Interactions; Female; Male; Pesticides; Phosphines; Poisoning; Pralidoxime Compounds; Rats; Rats, Wistar | 2001 |
Repeated measurements of aldicarb in blood and urine in a case of nonfatal poisoning.
Topics: Adult; Aldicarb; Atropine; Butyrylcholinesterase; Chromatography, High Pressure Liquid; Female; Half-Life; Humans; Insecticides; Poisoning; Pralidoxime Compounds; Suicide, Attempted; Treatment Outcome | 2001 |
Severe fenthion intoxications due to ingestion and inhalation with survival outcome.
Topics: Administration, Oral; Adolescent; Aged; Antidotes; Atropine; Environmental Exposure; Fenthion; Humans; Inhalation Exposure; Insecticides; Intensive Care Units; Male; Poisoning; Pralidoxime Compounds; Suicide, Attempted; Treatment Outcome | 2002 |
O-Substituted derivatives of pralidoxime: muscarinic properties and protection against soman effects in rats.
Topics: Acetylcholinesterase; Animals; Atropine; Binding, Competitive; Blood Pressure; Brain; Carbachol; Cholinergic Agonists; Cholinesterase Inhibitors; Cholinesterase Reactivators; Dose-Response Relationship, Drug; Female; Guinea Pigs; Heart Rate; Ileum; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle Contraction; Myocardium; Oximes; Pralidoxime Compounds; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Respiration; Soman; Structure-Activity Relationship; Submandibular Gland | 2002 |
[Experimental treatment of respiratory failure caused by omethoate poisoning in rats].
Topics: Animals; Antidotes; Atropine; Diaphragm; Dimethoate; Disease Models, Animal; Drug Therapy, Combination; Female; Male; Pralidoxime Compounds; Rats; Rats, Wistar; Recovery of Function; Respiration, Artificial; Respiratory Insufficiency | 2002 |
Potential use of autoinjector-packaged antidotes for treatment of pediatric nerve agent toxicity.
Topics: Antidotes; Atropine; Bioterrorism; Child; Disaster Planning; Equipment Design; Humans; Injections, Intramuscular; Injections, Jet; Parasympatholytics; Pralidoxime Compounds | 2002 |
Oral treatment of organophosphate poisoning in mice.
Topics: Animals; Antidotes; Atropine; Insecticides; Male; Mice; Mice, Inbred BALB C; Muscarinic Antagonists; Paraoxon; Parasympatholytics; Pralidoxime Compounds | 2003 |
Acute renal failure from organophospate poisoning: a case of success with haemofiltration.
Topics: Acute Kidney Injury; Adult; Antidotes; Atropine; Hemofiltration; Humans; Insecticides; Male; Organothiophosphorus Compounds; Pralidoxime Compounds; Suicide, Attempted; Treatment Outcome | 2003 |
Comparative efficacy of diazepam and avizafone against sarin-induced neuropathology and respiratory failure in guinea pigs: influence of atropine dose.
Topics: Animals; Anticonvulsants; Atropine; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Diazepam; Dipeptides; Drug Interactions; Electroencephalography; Guinea Pigs; Histocytochemistry; Muscarinic Antagonists; Nervous System Diseases; Pralidoxime Compounds; Prodrugs; Pyridostigmine Bromide; Respiratory Insufficiency; Sarin; Seizures | 2003 |
Neuroprotective effects of currently used antidotes in tabun-poisoned rats.
Topics: Animals; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Reactivators; Drug Therapy, Combination; Male; Motor Activity; Obidoxime Chloride; Organophosphate Poisoning; Organophosphates; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Rats; Rats, Wistar | 2003 |
Comparing therapeutic and prophylactic protection against the lethal effect of paraoxon.
Topics: Animals; Antidotes; Aryldialkylphosphatase; Atropine; Cholinesterase Reactivators; Drug Combinations; Insecticides; Lethal Dose 50; Liposomes; Male; Mice; Mice, Inbred BALB C; Muscarinic Antagonists; Neurotoxicity Syndromes; Paraoxon; Pralidoxime Compounds | 2004 |
Oximes and atropine in sarin poisoning.
Topics: Animals; Antidotes; Atropine; Cholinesterase Inhibitors; Diacetyl; Drug-Related Side Effects and Adverse Reactions; Guinea Pigs; Hydroxylamines; Mice; Organophosphate Poisoning; Oximes; Phosphates; Pralidoxime Compounds; Rats; Sarin | 1957 |
Protection against the lethal effects of organophosphates by pyridine-2-aldoxime methiodide.
Topics: Acetylcholinesterase; Animals; Atropine; Brain; Cholinesterases; Diphosphates; Mice; Organophosphates; Oximes; Paraoxon; Phosphates; Phosphorylation; Picolines; Pralidoxime Compounds | 1957 |
2-Hydroxyiminomethyl-N-methylpyridinium methanesulphonate and atropine in the treatment of severe organophosphate poisoning.
Topics: Animals; Atropine; Diphosphates; Humans; Insecticides; Male; Mesylates; Organophosphate Poisoning; Oximes; Phosphates; Pralidoxime Compounds; Pyrans; Pyridinium Compounds; Sarin | 1959 |
Oximes of alpha omega-diquaternary alkane salts as antidotes to organophosphate anticholinesterases.
Topics: Alkanes; Animals; Antidotes; Atropine; Cholinesterase Inhibitors; Hydroxylamines; Mice; Organophosphates; Oximes; Phosphates; Pralidoxime Compounds; Pyridines; Pyridinium Compounds; Salts | 1959 |
Protection against lethal organophosphate poisoning by quaternary pyridine aldoximes.
Topics: Animals; Antidotes; Atropine; Cholinesterase Inhibitors; Hydroxylamines; Isoflurophate; Mice; Neostigmine; Organophosphate Poisoning; Oximes; Phosphates; Pralidoxime Compounds; Pyrans; Pyridines; Pyridinium Compounds | 1959 |
The protective action of the oximes P2S and 2-PAM lactate alone or as adjuncts to atropine against GB vapor in dogs.
Topics: Animals; Atropine; Dogs; Hydroxylamines; Lactates; Lactic Acid; Oximes; Phosphates; Pralidoxime Compounds | 1960 |
Maximal inhibition of cholinesterase in the central nervous system.
Topics: Acetylcholine; Animals; Atropine; Central Nervous System; Cholinesterase Inhibitors; Cholinesterases; Mice; Nervous System; Pralidoxime Compounds | 1960 |
The effectiveness of 2-PAM and of EA 1814 as adjuncts to atropine therapy in dogs exposed to GB vapor by inhalation.
Topics: Animals; Atropine; Cholinesterase Inhibitors; Dogs; Gases; Phosphates; Pralidoxime Compounds; Pyridines | 1959 |
1,1'-Trimethylene bis(4-formylpyridinium bromide) dioxime (TMB-4) and 2-pyridine aldoxime methiodide (2-PAM) as adjuvants to atropine in the treatment of anticholinesterase poisoning.
Topics: Atropine; Bromides; Cholinesterase Inhibitors; Cyclopropanes; Hydroxylamines; Phosphates; Pralidoxime Compounds; Pyridines; Trimedoxime | 1960 |
Adjunctive value of oral prophylaxis with the oximes 2-PAM lactate and 2-PAM methanesulfonate to therapeutic administration of atropine in dogs poisoned by inhaled Sarin vapor.
Topics: Animals; Atropine; Cholinesterase Inhibitors; Dogs; Hydroxylamines; Lactic Acid; Mesylates; Oximes; Phosphates; Pralidoxime Compounds; Pyridines; Sarin | 1962 |
Effects of organophosphorous compounds, oximes and atropine injected into the third ventricle of unanaesthetized dogs.
Topics: Animals; Atropine; Brain; Cholinesterase Inhibitors; Dogs; Hydroxylamines; Insecticides; Isoflurophate; Oximes; Pralidoxime Compounds; Third Ventricle | 1962 |
[Protective effect of atropine, pyridine-2-aldoxime methiodide (PAM-2) and 1,3-trimethylenebis-(4-formylpyridinium bromide) dioxime (TMB-4) in experimental armine poisoning].
Topics: Armin; Atropine; Bromides; Hydroxylamines; Parasympathomimetics; Phosphates; Pralidoxime Compounds; Pyridines; Trimedoxime | 1962 |
Protection against alkylphosphate intoxication by intracerebral injection of 1-methyl-2-for-mylpyridinium iodide oxime (2-PAM).
Topics: Atropine; Drug-Related Side Effects and Adverse Reactions; Iodides; Organophosphate Poisoning; Oximes; Phosphorus; Poisons; Pralidoxime Compounds; Pyridines | 1962 |
Medical aspects of chemical warfare.
Topics: Atropine; Chemical Warfare; Chemical Warfare Agents; Gas Poisoning; Mass Casualty Incidents; Oximes; Pralidoxime Compounds | 1962 |
FURTHER THERAPEUTIC EXPERIENCE WITH PRALIDOXIMES IN ORGANIC PHOSPHORUS POISONING.
Topics: Atropine; Child; Diphosphates; Drug-Related Side Effects and Adverse Reactions; Organophosphate Poisoning; Oximes; Parathion; Phosphorus; Poisons; Pralidoxime Compounds; Pyridines; Toxicology | 1964 |
CLINICAL EVALUATION OF PROTOPAM.
Topics: Atropa belladonna; Atropine; Cataract; Cataract Extraction; Epinephrine; Geriatrics; Infant; Ophthalmology; Oximes; Parasympathomimetics; Pharmacology; Phenylephrine; Pralidoxime Compounds; Pyridines; Scopolamine; Toxicology; Uveitis | 1964 |
THE PROTECTIVE EFFECT OF PYRIDINE-2-ALDOXIME METHIODIDE (P2AM), BIS-(4-HYDROXYIMINO-METHYL-PYRIDINIUM-1-METHYL)-ETHER DICHLORIDE (TOXOGONIN) AND ATROPINE IN EXPERIMENTAL DDVP POISONING.
Topics: Animals; Antidotes; Atropine; Blood; Brain; Cholinesterase Inhibitors; Cholinesterases; Dichlorvos; Ethers; Horses; Insecticides; Mice; Obidoxime Chloride; Phosphates; Pralidoxime Compounds; Pyridines; Rats; Research; Succinylcholine; Toxicology | 1964 |
THE SYMPATHOMIMETIC EFFECTS OF 2-PYRIDINE ALDOXIME METHYLCHLORIDE (2-PAM CL).
Topics: Animals; Atropine; Blood; Blood Pressure; Catecholamines; Cats; Diphosphates; Dogs; Ganglia; Ganglionic Blockers; Heart; Hexamethonium Compounds; Methyl Chloride; Muscles; Neural Conduction; Nicotine; Nictitating Membrane; Norepinephrine; Pharmacology; Phenoxybenzamine; Pralidoxime Compounds; Research; Reserpine; Shock, Hemorrhagic; Sympathectomy; Sympathomimetics | 1965 |
CIGUATERA FISH POISON: A CHOLINESTERASE INHIBITOR.
Topics: Animals; Antidotes; Asphyxia; Atropine; Cholinesterase Inhibitors; Cholinesterases; Ciguatera Poisoning; Fishes; Mice; Pharmacology; Poisons; Pralidoxime Compounds; Rabbits; Rats; Research; Toxicology | 1965 |
USE OF PYRIDINE-2-ALDOXIME METHOCHLORIDE IN THE TREATMENT OF ORGANIC PHOSPHORUS COMPOUND POISONING IN LIVESTOCK.
Topics: Animals; Atropine; Cattle; Cattle Diseases; Cholinesterases; Clinical Enzyme Tests; Goats; Insecticides; Livestock; Pharmacology; Phosphates; Poisoning; Pralidoxime Compounds; Sheep; Sheep Diseases; Statistics as Topic; Toxicology | 1964 |
[Combined treatment of diethyl-p-nitrophenyl thiophosphate poisoning with pyridine-2-aldoxime methiodide and atropine].
Topics: Atropine; Combined Modality Therapy; Hydroxylamines; Parathion; Phosphates; Pralidoxime Compounds; Pyridines | 1960 |
Mechanism of the antagonism by pralidoxime and 1,1-trimethylenebis(4-hydroxyiminomethylpyridinium) of the action of echothiphate on the intestine.
Topics: Animals; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Echothiophate Iodide; Hydroxylamines; Intestine, Small; Intestines; Oximes; Parasympatholytics; Pralidoxime Compounds; Pyridines; Rabbits; Trimedoxime | 1962 |
The effectiveness of 2-PAM and TMB-4 as adjuncts to atropine therapy in dogs exposed to Sarin vapor by inhalation.
Topics: Animals; Atropine; Cholinesterase Inhibitors; Dogs; Hydroxylamines; Phosphates; Pralidoxime Compounds; Pyridines; Sarin; Trimedoxime | 1962 |
Pyridine-2-aldoxime methiodide. A valuable agent for phosphate poisoning.
Topics: Atropine; Drug Contamination; Humans; Hydroxylamines; Insecticides; Laboratories; Organophosphorus Compounds; Phosphates; Physicians; Pralidoxime Compounds; Pyridines; Pyrimidines; Suicidal Ideation | 1962 |
[Severe cases of parathion poisoning successfully treated with massive doses of pyridine-2 -aldoxime methiodide and atropine].
Topics: Atropine; Parathion; Pralidoxime Compounds; Pyridines | 1962 |
Organophosphate poisoning.
Topics: Animals; Antidotes; Atropine; Humans; Insecticides; Mice; Organophosphorus Compounds; Pralidoxime Compounds | 2003 |
Permanent paralysis at sites of dermal exposure to chlorpyrifos.
Topics: Atropine; Chlorpyrifos; Cholinesterase Reactivators; Humans; Insecticides; Male; Middle Aged; Muscarinic Antagonists; Muscle Weakness; Paralysis; Peripheral Nervous System Diseases; Pralidoxime Compounds | 2003 |
Nerve agent toxicology.
Topics: Antidotes; Atropine; Bioterrorism; Chemical Warfare Agents; Cholinesterase Reactivators; Emergency Treatment; Humans; Muscarinic Antagonists; Pralidoxime Compounds; United States | 2003 |
Effects of fosphenytoin on nerve agent-induced status epilepticus.
Topics: Animals; Anticonvulsants; Atropine; Chemical Warfare Agents; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroencephalography; Guinea Pigs; Injections, Intraperitoneal; Male; Phenytoin; Pralidoxime Compounds; Pyridostigmine Bromide; Soman; Status Epilepticus | 2004 |
The effect of plasmapheresis on plasma cholinesterase levels in a patient with organophosphate poisoning.
Topics: Antidotes; Atropine; Cholinesterase Reactivators; Cholinesterases; Fenitrothion; Humans; Insecticides; Male; Middle Aged; Plasmapheresis; Pralidoxime Compounds; Treatment Outcome | 2004 |
Organo-phosphate induced delayed neuropathy: report of two cases.
Topics: Adult; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Dichlorvos; Female; Humans; Insecticides; Male; Monocrotophos; Muscarinic Antagonists; Neurotoxicity Syndromes; Organophosphate Poisoning; Pralidoxime Compounds; Suicide, Attempted | 2004 |
Organophosphate poisoning in pregnancy: a case report.
Topics: Adult; Antidotes; Apgar Score; Atropine; Diazinon; Female; Gestational Age; Humans; Infant, Newborn; Poisoning; Pralidoxime Compounds; Pregnancy; Pregnancy Complications; Pregnancy Outcome | 2005 |
Pesticide poisoning in south India: opportunities for prevention and improved medical management.
Topics: Adolescent; Adult; Age Distribution; Antidotes; Atropine; Child; Endosulfan; Female; Humans; India; Insecticides; Length of Stay; Male; Middle Aged; Monocrotophos; Pesticides; Poisoning; Pralidoxime Compounds; Sex Distribution; Time Factors | 2005 |
Pralidoxime rescues both muscarinic and nicotinic systems.
Topics: Animals; Antidotes; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Humans; Muscarinic Antagonists; Organophosphorus Compounds; Pralidoxime Compounds; Receptors, Muscarinic; Receptors, Nicotinic; Swine; Swine, Miniature | 2005 |
Efficacy of an adenosine A1 receptor agonist compared with atropine and pralidoxime in a rat model of organophosphate poisoning.
Topics: Adenosine A1 Receptor Agonists; Animals; Antidotes; Atropine; Cholinesterase Reactivators; Cholinesterases; Diaphragm; Drug Interactions; Insecticides; Male; Models, Animal; Muscarinic Antagonists; Organothiophosphorus Compounds; Phenylisopropyladenosine; Poisoning; Pralidoxime Compounds; Rats; Rats, Wistar; Respiration; Salivation; Survival Rate; Time Factors | 2005 |
Novel neuroprotective effects with O-benzyl derivative of pralidoxime in soman-intoxicated rodents.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Analysis of Variance; Animals; Anticonvulsants; Atropine; Benzene Derivatives; Cholinesterase Inhibitors; Cholinesterase Reactivators; Corpus Striatum; Dopamine; Drug Synergism; Electroencephalography; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Mice; Microdialysis; Neuroprotective Agents; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Rats; Rats, Wistar; Seizures; Serotonin; Soman; Survival Rate; Time Factors | 2005 |
Atropine use in children after nerve gas exposure.
Topics: Anticonvulsants; Antidotes; Atropine; Chemical Warfare Agents; Child; Cholinesterase Reactivators; Disaster Planning; Humans; Muscarinic Antagonists; Neurotoxins; Pediatrics; Poisoning; Practice Guidelines as Topic; Pralidoxime Compounds; Terrorism; United States | 2005 |
Protective effect induced by atropine, carbamates, and 2-pyridine aldoxime methoiodide Artemia salina larvae exposed to fonofos and phosphamidon.
Topics: Age Factors; Animals; Artemia; Atropine; Carbamates; Cholinesterase Inhibitors; Cholinesterase Reactivators; Fonofos; Insecticides; Larva; Muscarinic Antagonists; Phosphamidon; Pralidoxime Compounds; Toxicity Tests | 2007 |
The "intermediate syndrome" as critical sequelae of organophosphate poisoning: the first report of two cases in Thailand.
Topics: Adult; Atropine; Female; Humans; Insecticides; Male; Muscle Weakness; Organophosphate Poisoning; Paralysis; Pralidoxime Compounds; Respiratory Insufficiency; Syndrome; Thailand; Time Factors | 2005 |
Pediatric nerve agent poisoning: medical and operational considerations for emergency medical services in a large American city.
Topics: Antidotes; Atropine; Chemical Terrorism; Chemical Warfare Agents; Child; Child, Preschool; Clinical Protocols; Disaster Planning; Emergency Medical Services; Humans; Infant; Infant, Newborn; Needles; New York City; Pediatrics; Pralidoxime Compounds | 2006 |
The use of serial measurement of plasma cholinesterase in the management of acute poisoning with organophosphates and carbamates.
Topics: Adolescent; Adult; Antidotes; Atropine; Butyrylcholinesterase; Carbamates; Child, Preschool; Cholinesterase Reactivators; Female; Forensic Medicine; Humans; Male; Middle Aged; Muscarinic Antagonists; Poisoning; Pralidoxime Compounds | 2006 |
Overcoming inhibitions.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Atropine; Benzodiazepines; Blood-Brain Barrier; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Drug Therapy, Combination; Galantamine; Guinea Pigs; Insecticides; Neurons; Neurotransmitter Agents; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Paraoxon; Pralidoxime Compounds; Pyridostigmine Bromide; Receptors, Cholinergic; Receptors, Muscarinic; Sarin; Seizures; Soman; Time Factors | 2006 |
Respiratory failure in organophosphate insecticide poisoning.
Topics: Adolescent; Adult; Age Distribution; Antidotes; Atropine; Chi-Square Distribution; Cohort Studies; Emergency Service, Hospital; Female; Humans; Incidence; Infusions, Intravenous; Insecticides; Iran; Male; Middle Aged; Organophosphate Poisoning; Pralidoxime Compounds; Prognosis; Respiratory Insufficiency; Retrospective Studies; Risk Assessment; Severity of Illness Index; Sex Distribution; Suicide, Attempted; Survival Analysis; Treatment Outcome | 2007 |
Pralidoxime in carbaryl poisoning: an animal model.
Topics: Animals; Antidotes; Atropine; Carbaryl; Cholinesterase Inhibitors; Cholinesterase Reactivators; Drug Therapy, Combination; Female; Insecticides; Mice; Mice, Inbred ICR; Poisoning; Pralidoxime Compounds | 2007 |
High-dose pralidoxime for organophosphorus poisoning.
Topics: Atropine; Cholinesterase Reactivators; Dose-Response Relationship, Drug; Humans; Organophosphate Poisoning; Parasympatholytics; Pralidoxime Compounds; Randomized Controlled Trials as Topic | 2007 |
High-dose pralidoxime for organophosphorus poisoning.
Topics: Atropine; Cholinesterase Reactivators; Clinical Trials as Topic; Ethics, Research; Humans; Mortality; Muscarinic Antagonists; Organophosphate Poisoning; Pralidoxime Compounds | 2007 |
High-dose pralidoxime for organophosphorus poisoning.
Topics: Atropine; Cholinesterase Reactivators; Humans; Intubation, Intratracheal; Muscarinic Antagonists; Organophosphate Poisoning; Pralidoxime Compounds; Respiration, Artificial; Time Factors | 2007 |
Hyperamylasemia and acute pancreatitis following anticholinesterase poisoning.
Topics: Acute Disease; Adolescent; Adult; Amylases; Atropine; Butyrylcholinesterase; Carbamates; Cholinesterase Inhibitors; Cholinesterase Reactivators; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Hyperamylasemia; Male; Middle Aged; Occupational Exposure; Organophosphate Poisoning; Organophosphates; Pancreatitis; Pralidoxime Compounds; Prospective Studies; Radiography; Respiration, Artificial; Suicide, Attempted; Transaminases; Ultrasonography | 2007 |
Toxicity and characterization of cholinesterase-inhibition induced by diisopropyl fluorophosphate in Artemia salina larvae.
Topics: Animals; Artemia; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Drug Therapy, Combination; Isoflurophate; Larva; Longevity; Muscarinic Antagonists; Physostigmine; Pralidoxime Compounds; Pyridostigmine Bromide; Toxicity Tests, Acute; Water Pollutants, Chemical | 2009 |
Nerve agents: implications for anesthesia providers.
Topics: Antidotes; Atropine; Chemical Terrorism; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Decontamination; Humans; Muscarinic Antagonists; Nurse Anesthetists; Nurse's Role; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Pralidoxime Compounds; Sarin; Soman; Time Factors | 2008 |
A structure-activity analysis of the variation in oxime efficacy against nerve agents.
Topics: Acetylcholinesterase; Animals; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Erythrocytes; Guinea Pigs; Linear Models; Male; Obidoxime Chloride; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Sarin; Structure-Activity Relationship | 2008 |
Epidemiology of organophosphate pesticide poisoning in Taiwan.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidotes; Atropine; Child; Child, Preschool; Female; Humans; Infant; Male; Middle Aged; Organophosphate Poisoning; Pesticides; Poison Control Centers; Poisoning; Pralidoxime Compounds; Retrospective Studies; Suicide, Attempted; Taiwan | 2008 |
High-performance liquid chromatography coupled with electrospray tandem mass spectrometry (LC/MS/MS) method for the simultaneous determination of diazepam, atropine and pralidoxime in human plasma.
Topics: Atropine; Chromatography, High Pressure Liquid; Diazepam; Humans; Pralidoxime Compounds; Reproducibility of Results; Tandem Mass Spectrometry | 2008 |
Chinese dumpling scare hits Japan--a case of methamidophos food poisoning.
Topics: Atropine; Child, Preschool; China; Coma; Female; Foodborne Diseases; Humans; Insecticides; Japan; Midazolam; Organothiophosphorus Compounds; Pralidoxime Compounds | 2008 |
Hypotension in severe dimethoate self-poisoning.
Topics: Antidotes; Atropine; Cardiotonic Agents; Dimethoate; Humans; Hypotension; Insecticides; Male; Middle Aged; Pralidoxime Compounds; Suicide; Vasodilation | 2008 |
The use of OpdA in rat models of organic phosphorus (OP) poisoning.
Topics: Animals; Aryldialkylphosphatase; Atropine; Bacterial Proteins; Cholinesterase Reactivators; Drug Synergism; Organophosphate Poisoning; Parasympathetic Nervous System; Pralidoxime Compounds; Rats; Synapses | 2009 |
Organophosphate poisoning due to a wheat bagel.
Topics: Acetylcholinesterase; Adolescent; Adult; Antidotes; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Dichlorvos; Female; Food Contamination; Foodborne Diseases; Humans; Insecticides; Male; Organophosphate Poisoning; Pralidoxime Compounds; Retrospective Studies; Triticum; Turkey; Young Adult | 2009 |
Cardiac damage in acute organophosphate poisoning in rats: effects of atropine and pralidoxime.
Topics: Acute Disease; Analysis of Variance; Animals; Antidotes; Atropine; Biomarkers; Cholinesterase Inhibitors; Dichlorvos; Heart; Immunohistochemistry; In Situ Nick-End Labeling; Male; Nitric Oxide; Organophosphate Poisoning; Pralidoxime Compounds; Random Allocation; Rats; Rats, Wistar; Survival Rate | 2009 |
Urinary elimination kinetics of acephate and its metabolite, methamidophos, in urine after acute ingestion.
Topics: Antidotes; Atmospheric Pressure; Atropine; Butyrylcholinesterase; Child, Preschool; Chromatography, High Pressure Liquid; Drug Therapy, Combination; Erythrocytes; Humans; Insecticides; Male; Muscarinic Antagonists; Organothiophosphorus Compounds; Phosphoramides; Poisoning; Pralidoxime Compounds; Respiration, Artificial; Tandem Mass Spectrometry; Treatment Outcome | 2009 |
Galantamine is a novel post-exposure therapeutic against lethal VX challenge.
Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diaphragm; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroencephalography; Erythrocytes; Galantamine; Guinea Pigs; Male; Muscle Fatigue; Muscle Tonus; Neurotoxicity Syndromes; Organothiophosphorus Compounds; Paralysis; Phrenic Nerve; Pralidoxime Compounds; Seizures; Time Factors | 2009 |
Treatment with tertiary oximes prevents seizures and improves survival following sarin intoxication.
Topics: Acetylcholinesterase; Animals; Atropine; Brain; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diacetyl; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Guinea Pigs; Injections, Intramuscular; Male; Muscarinic Antagonists; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Pyridostigmine Bromide; Sarin; Seizures; Treatment Outcome; Up-Regulation | 2010 |
Use of pralidoxime without atropine in rivastigmine (carbamate) toxicity.
Topics: Administration, Cutaneous; Aged, 80 and over; Alzheimer Disease; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Drug Overdose; Female; Humans; Phenylcarbamates; Pralidoxime Compounds; Rivastigmine; Treatment Outcome | 2009 |
Formulation of effects of atropine, pralidoxime and magnesium sulfate on cardiac tissue levels of nitric oxide, malondialdehyde and glutathione in organophosphate poisoning using artificial neural network.
Topics: Animals; Anti-Arrhythmia Agents; Antidotes; Atropine; Dichlorvos; Glutathione; Insecticides; Magnesium Sulfate; Male; Malondialdehyde; Muscarinic Antagonists; Myocardium; Neural Networks, Computer; Nitric Oxide; Poisoning; Pralidoxime Compounds; Random Allocation; Rats; Rats, Wistar | 2010 |
Hypothermia and Fever after organophosphorus poisoning in humans--a prospective case series.
Topics: Adolescent; Adult; Aged; Antidotes; Atropine; Body Temperature Regulation; Female; Fever; Humans; Hypothermia; Insecticides; Male; Middle Aged; Organophosphate Poisoning; Palliative Care; Pralidoxime Compounds; Prospective Studies; Suicide, Attempted; Young Adult | 2010 |
Guillain-Barre syndrome due to organophosphate compound poison.
Topics: Adult; Atropine; Chlorpyrifos; Cholinesterase Inhibitors; Cholinesterase Reactivators; Gastric Lavage; Guillain-Barre Syndrome; Humans; Insecticides; Male; Methylprednisolone; Neuroprotective Agents; Parasympatholytics; Plasmapheresis; Pralidoxime Compounds | 2009 |
Transplacentally acquired organophosphorus poisoning in a newborn: case report.
Topics: Antitoxins; Atropine; Female; Humans; Infant, Newborn; Organophosphates; Poisoning; Pralidoxime Compounds; Pregnancy; Pregnancy Complications; Suicide, Attempted | 2010 |
Effects of atropine and pralidoxime on neuronal actions of paraoxon in rat hippocampal slices.
Topics: Animals; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Excitatory Postsynaptic Potentials; Hippocampus; Muscarinic Antagonists; Neurons; Organ Culture Techniques; Paraoxon; Patch-Clamp Techniques; Pralidoxime Compounds; Rats; Rats, Wistar; Synaptic Transmission | 2010 |
Benefit of nanocarrier of magnetic magnesium in rat malathion-induced toxicity and cardiac failure using non-invasive monitoring of electrocardiogram and blood pressure.
Topics: Acetylcholinesterase; Animals; Antioxidants; Atropine; Biomarkers; Blood Pressure; Disease Models, Animal; Electrocardiography; Heart Failure; Heart Rate; Lethal Dose 50; Lipid Peroxidation; Magnesium; Magnesium Sulfate; Magnetics; Malathion; Male; Metal Nanoparticles; Oxidative Stress; Pralidoxime Compounds; Rats; Rats, Wistar; Sulfhydryl Compounds | 2011 |
[Multiple organ dysfunction in acute organophosphate poisoning].
Topics: Acetylcholinesterase; Adult; APACHE; Atropine; Cholinesterases; Erythrocytes; Female; Humans; Male; Multiple Organ Failure; Muscarinic Antagonists; Parathion; Poisoning; Pralidoxime Compounds; Receptors, Muscarinic; Receptors, Nicotinic; Respiratory Distress Syndrome; Retrospective Studies; Severity of Illness Index; Spain; Suicide, Attempted; Young Adult | 2011 |
Severe and prolonged neurologic toxicity following subcutaneous chlorpyrifos self-administration: a case report.
Topics: Antidotes; Atropine; Brain; Chlorpyrifos; Humans; Injections, Subcutaneous; Insecticides; Magnetic Resonance Imaging; Male; Muscarinic Antagonists; Nervous System Diseases; Poisoning; Pralidoxime Compounds; Suicide, Attempted; Treatment Outcome; Young Adult | 2011 |
A cembranoid protects acute hippocampal slices against paraoxon neurotoxicity.
Topics: Acetylcholinesterase; Animals; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diterpenes; Dose-Response Relationship, Drug; Hippocampus; Male; Neuroprotective Agents; Paraoxon; Parasympatholytics; Pralidoxime Compounds; Rats; Rats, Sprague-Dawley | 2011 |
Atypical central nervous system involvement in acute organophosphorous poisoning.
Topics: Adult; Antidotes; Atropine; Basal Ganglia Diseases; Brain; Dimethoate; Female; Humans; Insecticides; Muscarinic Antagonists; Organophosphate Poisoning; Pralidoxime Compounds; Tomography, X-Ray Computed | 2011 |
Transcriptional analysis of rat piriform cortex following exposure to the organophosphonate anticholinesterase sarin and induction of seizures.
Topics: Animals; Anticonvulsants; Atropine; Brain; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diazepam; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; Humans; Male; Microarray Analysis; Muscarinic Antagonists; Pralidoxime Compounds; Principal Component Analysis; Rats; Rats, Sprague-Dawley; Sarin; Seizures; Signal Transduction; Transcription, Genetic | 2011 |
Neuroprotective effects of imidazenil against chemical warfare nerve agent soman toxicity in guinea pigs.
Topics: Acetylcholinesterase; Analysis of Variance; Animals; Atropine; Benzodiazepines; Body Weight; Brain; Chemical Warfare Agents; Cholinesterase Reactivators; Disease Models, Animal; Drug Administration Schedule; Electrocardiography; Electroencephalography; Guinea Pigs; Imidazoles; Lethal Dose 50; Male; Muscarinic Antagonists; Neuroprotective Agents; Neurotoxicity Syndromes; Pralidoxime Compounds; Seizures; Soman; Telemetry; Time Factors | 2012 |
A rare case of combined strychnine and propoxur toxicity from a single preparation.
Topics: Adult; Atropine; Charcoal; Diazepam; Drug Combinations; Gastric Lavage; Humans; Insecticides; Intubation, Gastrointestinal; Male; Midazolam; Poisoning; Poisons; Pralidoxime Compounds; Propoxur; Spasm; Strychnine; Suicide, Attempted | 2012 |
Amitraz poisoning -- familiar presentation, unfamiliar diagnosis.
Topics: Adult; Antidotes; Atropine; Cardiotonic Agents; Cholinesterase Reactivators; Cholinesterases; Coma; Dopamine; Humans; Insecticides; Male; Muscarinic Antagonists; Pralidoxime Compounds; Suicide, Attempted; Toluidines | 2012 |
Case report: an unusual heart rhythm associated with organophosphate poisoning.
Topics: Anti-Arrhythmia Agents; Antidotes; Atrial Fibrillation; Atropine; Bundle-Branch Block; Drug Therapy, Combination; Electrocardiography; Heart; Humans; Long QT Syndrome; Male; Middle Aged; Organophosphate Poisoning; Pralidoxime Compounds; Suicide, Attempted; Tachycardia, Paroxysmal; Treatment Outcome | 2012 |
Rapid and complete bioavailability of antidotes for organophosphorus nerve agent and cyanide poisoning in minipigs after intraosseous administration.
Topics: Animals; Antidotes; Atropine; Biological Availability; Chemical Warfare Agents; Cyanides; Hydroxocobalamin; Infusions, Intraosseous; Infusions, Intravenous; Injections, Intramuscular; Male; Organophosphate Poisoning; Pralidoxime Compounds; Swine; Swine, Miniature; Time Factors | 2012 |
An in vivo zebrafish screen identifies organophosphate antidotes with diverse mechanisms of action.
Topics: Animals; Antidotes; Atropine; Cell Line, Tumor; Cholinergic Antagonists; Cholinesterase Reactivators; Drug Evaluation, Preclinical; Emetine; Glycopyrrolate; High-Throughput Screening Assays; Humans; Lethal Dose 50; Metoclopramide; Neostigmine; Organophosphates; Parathion; Pirenzepine; Pralidoxime Compounds; Zebrafish | 2013 |
Recurrent neonatal organophoshorus poisoning.
Topics: Atropine; Diazinon; Female; Humans; Infant, Newborn; Insecticides; Organophosphate Poisoning; Pralidoxime Compounds; Recurrence | 2012 |
The effects of ubiquinone (CoQ10) on heart tissue in cardiac toxicity related to organophosphate poisoning.
Topics: Acetylcholinesterase; Animals; Antioxidants; Atropine; Cholinesterase Reactivators; Drug Therapy, Combination; Erythrocytes; Female; Heart Diseases; Lipid Peroxidation; Male; Malondialdehyde; Myocardium; Nitric Oxide; Organophosphate Poisoning; Pralidoxime Compounds; Rabbits; Ubiquinone | 2013 |
Diabetic ketoacidosis: an uncommon manifestation of pesticide poisoning.
Topics: Adolescent; Atropine; Diabetic Ketoacidosis; Female; Humans; Pesticides; Pralidoxime Compounds; Risk Factors | 2013 |
Aldicarb: a case series of watermelon-borne carbamate toxicity.
Topics: Administration, Oral; Adult; Aldicarb; Atropine; Citrullus; Food Contamination; Humans; Insecticides; Male; Middle Aged; Poisoning; Pralidoxime Compounds; Retrospective Studies; Young Adult | 2013 |
Repeated pulse intramuscular injection of pralidoxime chloride in severe acute organophosphorus pesticide poisoning.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidotes; Atropine; Drug Therapy, Combination; Female; Humans; Injections, Intramuscular; Intensive Care Units; Length of Stay; Male; Middle Aged; Organophosphate Poisoning; Pralidoxime Compounds; Retrospective Studies; Young Adult | 2013 |
Fresh frozen plasma as a successful antidotal supplement in acute organophosphate poisoning.
Topics: Acetylcholinesterase; Antidotes; Atropine; Blood Transfusion; Butyrylcholinesterase; Erythrocytes; Gastric Lavage; Humans; Insecticides; Malathion; Male; Middle Aged; Organophosphate Poisoning; Plasma; Pralidoxime Compounds; Serum Albumin; Serum Albumin, Human | 2013 |
Can anisodamine be a potential substitute for high-dose atropine in cases of organophosphate poisoning?
Topics: Antidotes; Atropine; Cholinesterase Reactivators; Female; Humans; Insecticides; Middle Aged; Muscarinic Antagonists; Organophosphate Poisoning; Pralidoxime Compounds; Solanaceous Alkaloids | 2014 |
Development of status epilepticus, sustained calcium elevations and neuronal injury in a rat survival model of lethal paraoxon intoxication.
Topics: Animals; Anticonvulsants; Atropine; Brain; Calcium; Diazepam; Disease Models, Animal; Electroencephalography; Hippocampus; Male; Neurons; Organophosphate Poisoning; Paraoxon; Pralidoxime Compounds; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2014 |
Body mass index as a prognostic factor in organophosphate-poisoned patients.
Topics: Adult; Aged; Atropine; Body Mass Index; Cholinesterase Reactivators; Cohort Studies; Female; Glasgow Coma Scale; Humans; Intensive Care Units; Length of Stay; Male; Middle Aged; Muscarinic Antagonists; Obesity; Organophosphate Poisoning; Organophosphates; Pralidoxime Compounds; Prognosis; Respiration, Artificial; Retrospective Studies; Severity of Illness Index; Solubility | 2014 |
Chronic behavioral and cognitive deficits in a rat survival model of paraoxon toxicity.
Topics: Anhedonia; Animals; Anxiety; Atropine; Behavior, Animal; Cognition Disorders; Depression; Diazepam; Male; Memory Disorders; Organophosphate Poisoning; Paraoxon; Pralidoxime Compounds; Rats; Rats, Sprague-Dawley; Recognition, Psychology | 2014 |
In vivo protection of diisopropylphosphorofluoridate (DFP) poisoning by three bis-quaternary 2 -(hydroxyimino) -N -(pyridin-3-yl) acetamide derivatives in Swiss mice.
Topics: Acetylcholinesterase; Animals; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Isoflurophate; Male; Mice; Oximes; Poisoning; Pralidoxime Compounds | 2014 |
Organophosphorus poisoning presentating as diabetic ketoacidosis: a real challenge for the endocrinologist.
Topics: Administration, Intravenous; Antidotes; Atropine; Child; Cholinesterases; Diabetic Ketoacidosis; Diagnosis, Differential; Humans; Male; Organophosphate Poisoning; Pesticides; Pralidoxime Compounds; Treatment Outcome | 2014 |
An exploratory study; the therapeutic effects of premixed activated charcoal-sorbitol administration in patients poisoned with organophosphate pesticide.
Topics: Adult; Aged; Antidotes; Atropine; Cathartics; Charcoal; Cholinesterase Reactivators; Drug Combinations; Female; Glasgow Coma Scale; Humans; Male; Middle Aged; Muscarinic Antagonists; Organophosphate Poisoning; Pesticides; Pralidoxime Compounds; Retrospective Studies; Sorbitol | 2015 |
Chronic Treatment with Naltrexone Prevents Memory Retention Deficits in Rats Poisoned with the Sarin Analog Diisopropylfluorophosphate (DFP) and Treated with Atropine and Pralidoxime.
Topics: Animals; Atropine; Female; Isoflurophate; Memory Disorders; Naltrexone; Pralidoxime Compounds; Rats; Rats, Long-Evans | 2015 |
Acute severe organophosphate poisoning in a child who was successfully treated with therapeutic plasma exchange, high-volume hemodiafiltration, and lipid infusion.
Topics: Atropine; Child; Hemodiafiltration; Humans; Infusions, Intravenous; Lipids; Organophosphate Poisoning; Plasma Exchange; Pralidoxime Compounds; Salvage Therapy | 2016 |
Amitraz: a mimicker of organophosphate poisoning.
Topics: Atropine; Bradycardia; Cholinesterase Reactivators; Diagnosis, Differential; Diagnostic Errors; Follow-Up Studies; Humans; Hyperglycemia; Hypotension; Male; Miosis; Organophosphate Poisoning; Parasympatholytics; Pralidoxime Compounds; Suicide, Attempted; Toluidines; Treatment Outcome; Young Adult | 2015 |
Neuroprotection Against Diisopropylfluorophosphate in Acute Hippocampal Slices.
Topics: Acetylcholinesterase; Animals; Atropine; Cholinesterase Inhibitors; Hippocampus; Isoflurophate; Male; Neuroprotection; Neuroprotective Agents; Pralidoxime Compounds; Rats, Sprague-Dawley; Synapses | 2015 |
Efficacy of Recommended Prehospital Human Equivalent Doses of Atropine and Pralidoxime Against the Toxic Effects of Carbamate Poisoning in the Hartley Guinea Pig.
Topics: Acetylcholinesterase; Aldicarb; Animals; Antidotes; Atropine; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Cholinesterase Reactivators; Emergency Medical Services; Guinea Pigs; Humans; Insecticides; Male; Methomyl; Muscarinic Antagonists; Organophosphate Poisoning; Pralidoxime Compounds | 2016 |
Toxicity and median effective doses of oxime therapies against percutaneous organophosphorus pesticide and nerve agent challenges in the Hartley guinea pig.
Topics: Animals; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Dose-Response Relationship, Drug; Guinea Pigs; Lethal Dose 50; Male; Muscarinic Antagonists; Obidoxime Chloride; Organophosphate Poisoning; Organothiophosphorus Compounds; Oximes; Pesticides; Pralidoxime Compounds; Pyridinium Compounds; Time Factors | 2016 |
A rodent model of human organophosphate exposure producing status epilepticus and neuropathology.
Topics: Animals; Antidotes; Atropine; Central Nervous System Diseases; Cholinesterase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Male; Organophosphates; Phosphoric Triester Hydrolases; Pralidoxime Compounds; Pyridostigmine Bromide; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2016 |
Toxic megacolon as a rare complication following atropine therapy due to organophosphate poisoning: A case report.
Topics: Antidotes; Atropine; Drug Therapy, Combination; Humans; Male; Megacolon, Toxic; Middle Aged; Organophosphate Poisoning; Pralidoxime Compounds | 2017 |
The role of plasmapheresis in organophosphate poisoning: Case reports of three pediatric patients.
Topics: Adolescent; Atropine; Child; Child, Preschool; Cholinesterase Reactivators; Female; Humans; Male; Organophosphate Poisoning; Plasmapheresis; Pralidoxime Compounds | 2017 |
Method validation for simultaneous determination of atropine, pralidoxime and 12 organophosphorus compounds in blood samples by means of high-performance liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS).
Topics: Animals; Atropine; Chromatography, High Pressure Liquid; Humans; Limit of Detection; Linear Models; Male; Organophosphorus Compounds; Pralidoxime Compounds; Rats; Rats, Wistar; Reproducibility of Results; Tandem Mass Spectrometry | 2018 |
Organophosphorus Compounds Poisoning in a Neonate: A Case Report.
Topics: Antidotes; Atropine; Humans; Infant, Newborn; Insecticides; Male; Organophosphate Poisoning; Organophosphorus Compounds; Pralidoxime Compounds; Treatment Outcome | 2019 |
Pyridostigmine Suicidal Attempt in a Myasthenia Gravis Patient.
Topics: Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Female; Humans; Middle Aged; Muscarinic Antagonists; Myasthenia Gravis; Pralidoxime Compounds; Pyridostigmine Bromide; Suicide, Attempted | 2019 |
Clinical effects from household insecticide: pyrethroid or organophosphate toxicity?
Topics: Antidotes; Atropine; Diagnosis, Differential; Household Products; Humans; Insecticides; Male; Middle Aged; Organophosphate Poisoning; Pralidoxime Compounds; Pyrethrins | 2019 |
The antidotes atropine and pralidoxime distinctively recover cardiorespiratory components impaired by acute poisoning with chlorpyrifos in rats.
Topics: Animals; Antidotes; Atropine; Baroreflex; Blood Pressure; Bradycardia; Cardiovascular System; Chlorpyrifos; Cholinesterase Inhibitors; Heart Rate; Insecticides; Male; Organophosphate Poisoning; Pralidoxime Compounds; Rats; Rats, Wistar; Respiratory System | 2020 |
Mechanism of central hypopnoea induced by organic phosphorus poisoning.
Topics: Animals; Atropine; Brain; Organophosphate Poisoning; Paraoxon; Pralidoxime Compounds; Rats; Respiratory Burst; Sleep Apnea, Central | 2020 |
Outcomes of elderly patients with organophosphate intoxication.
Topics: Acute Kidney Injury; Affect; Aged; Antidotes; Atropine; Chlorpyrifos; Female; Humans; Insecticides; Male; Mevinphos; Middle Aged; Organophosphate Poisoning; Organothiophosphorus Compounds; Pneumonia, Aspiration; Pralidoxime Compounds; Psychotic Disorders; Respiratory Insufficiency; Retrospective Studies; Seizures; Shock; Survival Analysis; Treatment Outcome | 2021 |
A delayed treatment model for the evaluation of scopolamine for VX nerve agent intoxication.
Topics: Animals; Atropine; Chemical Warfare Agents; Cholinergic Antagonists; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Therapy, Combination; Guinea Pigs; Male; Midazolam; Nerve Agents; Organothiophosphorus Compounds; Pralidoxime Compounds; Scopolamine; Survival Rate; Time-to-Treatment | 2021 |
Loading and Sustained Release of Pralidoxime Chloride from Swellable MIL-88B(Fe) and Its Therapeutic Performance on Mice Poisoned by Neurotoxic Agents.
Topics: Acetylcholinesterase; Administration, Oral; Animals; Atropine; Dose-Response Relationship, Drug; Male; Metal-Organic Frameworks; Mice; Mice, Inbred Strains; Nanoparticles; Nerve Agents; Pralidoxime Compounds; Sarin | 2022 |
Succinate prodrugs in combination with atropine and pralidoxime protect cerebral mitochondrial function in a rodent model of acute organophosphate poisoning.
Topics: Acetylcholinesterase; Animals; Atropine; Brain Injuries; Isoflurophate; Mitochondria; Organophosphate Poisoning; Prodrugs; Rats; Rodentia; Succinates; Succinic Acid | 2022 |
The lesion site of organophosphorus-induced central apnea and the effects of antidotes.
Topics: Animals; Antidotes; Atropine; Neostigmine; Paraoxon; Pralidoxime Compounds; Pyridines; Rats; Rats, Sprague-Dawley; Sleep Apnea, Central | 2023 |