Compounds > atropine
Page last updated: 2024-09-05

atropine and picrotoxinin

atropine has been researched along with picrotoxinin in 4 studies

Compound Research Comparison

Studies
(atropine)		Trials
(atropine)		Recent Studies (post-2010)
(atropine)		Studies
(picrotoxinin)		Trials
(picrotoxinin)		Recent Studies (post-2010) (picrotoxinin)
26,7111,2591,6971508
26,7111,2591,697158024

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)picrotoxinin (IC50)
Glycine receptor subunit alpha-2Rattus norvegicus (Norway rat)2.4

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K1
Fincher, AS; Frye, GD; Griffith, WH; Lorenzetti, M; Trzeciakowski, J1
Pencheva, N; Radomirov, R1

Other Studies

4 other study(ies) available for atropine and picrotoxinin

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
    Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21

    Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes, Liver; Neuralgia; Nociceptin Receptor; Pyrroles; Rats; Receptors, Opioid; Structure-Activity Relationship

2010
Comparison of contractile responses of the guinea pig ileum longitudinal muscle to ethanol and GABAA agonists.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 252, Issue:2

    Topics: Animals; Atropine; Bicuculline; Chlorides; Ethanol; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Pentobarbital; Picrotoxin; Receptors, GABA-A; Sesterterpenes; Taurine; Tetrodotoxin

1990
Biphasic GABA-A receptor-mediated effect on the spontaneous activity of the circular layer in cat terminal ileum.
    General pharmacology, 1993, Volume: 24, Issue:4

    Topics: Animals; Atropine; Baclofen; Bicuculline; Cats; gamma-Aminobutyric Acid; Ileum; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Picrotoxin; Receptors, GABA-A; Sesterterpenes; Tetrodotoxin

1993