Page last updated: 2024-09-05

atropine and phencyclidine

atropine has been researched along with phencyclidine in 56 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(phencyclidine)
Trials
(phencyclidine)
Recent Studies (post-2010) (phencyclidine)
26,7111,2591,69728,2943877,796

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)phencyclidine (IC50)
Glutamate receptor ionotropic, NMDA 1 Rattus norvegicus (Norway rat)0.1299
Lysosomal Pro-X carboxypeptidaseHomo sapiens (human)0.091
Glutamate receptor ionotropic, NMDA 2A Rattus norvegicus (Norway rat)0.1299
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)0.1299
Glutamate receptor ionotropic, NMDA 2CRattus norvegicus (Norway rat)0.1299
Glutamate receptor ionotropic, NMDA 1Homo sapiens (human)0.5563
Glutamate receptor ionotropic, NMDA 2AHomo sapiens (human)0.205
Glutamate receptor ionotropic, NMDA 2BHomo sapiens (human)1.2589
Glutamate receptor ionotropic, NMDA 2DRattus norvegicus (Norway rat)0.1299
Glutamate receptor ionotropic, NMDA 3BRattus norvegicus (Norway rat)0.1299
Sigma non-opioid intracellular receptor 1Rattus norvegicus (Norway rat)0.53
Glutamate receptor ionotropic, NMDA 3ARattus norvegicus (Norway rat)0.1299

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-199036 (64.29)18.7374
1990's14 (25.00)18.2507
2000's5 (8.93)29.6817
2010's1 (1.79)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baldy, WJ; Davis, CB; DiStefano, DL; Elgin, RJ; Fedde, CL; Kesslick, JM; Martin, GE; Mathiasen, JR; Scott, MK; Shank, RP1
Bauer, C; Caldwell, L; Kinnier, WJ; Lancaster, J; McMillan, B; Price, CH; Sweetnam, PM1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Balster, RL; Chait, LD1
Abboud, R; Chan-Yeung, M1
Dorand, RD1
Maayani, S; Sokolovsky, M; Treister, G1
Lapin, IP; Rogawski, MA1
Carlsson, M; Svensson, A1
Herrera, DG; Robertson, HA1
Jope, RS; Li, X; Ormandy, GC1
Marien, MR; Richard, JW1
Boggan, WO; Faught, K; Middaugh, LD1
Leung, LW1
Kameyama, M; Nabatame, H; Ohno, Y; Sasa, M; Takaori, S1
Byrd, LD; Howell, LL; Standish, LJ1
Boggan, WO; Faught, K; Middaugh, LD; Stringer, AJ1
Bailey, DN; Briggs, JR; Coffee, JJ1
Holland, AJ1
Boyd, EH; Boyd, ES; Brown, LE1
Darrow, CC; Leiseca, SA; Martin, DP; Valerio, DA1
Henriksson, BG; Järbe, TU1
Nadel, JA1
Becker, M; Stauffer, UG1
Priano, LL; Traber, DL; Wilson, RD1
Boughton, E; Done, JT; Kidd, AR1
Bouhuys, A1
Corne, SJ; Pickering, RW1
Aghajanian, GK; Foote, WE; Sheard, MH1
Schneider, C1
Leung, LS1
Adams, PM1
Morton, EC; Vaupel, DB1
Maayani, S; Pazhenchevsky, B; Weinstein, H1
Peatfield, AC; Richardson, PS1
Chaturvedi, AK1
Leander, JD1
Johnson, KM; Leventer, SM1
Holsapple, MP; Malave, A; Yim, GK1
Johnson, KM1
Blanchet, G; Bodjarian, N; Carpentier, P; Denoyer, M; Foquin-Tarricone, A; Kamenka, JM; Lallement, G; Lerner-Natoli, M; Rondouin, G1
Baubichon, D; Blanchet, G; Burckhart, MF; Carpentier, P; Lallement, G; Pernot-Marino, I1
Baubichon, D; Blanchet, G; Carpentier, P; Foquin-Tarricone, A; Lallement, G; Pernot-Marino, I; Piras, A1
Buck, MG; Goswami, S; Maayani, S; Marom, Z; Rienzi, N; Schachter, EN; Zuskin, E1
Castranova, V; Goswami, S; Maayani, S; Mustajbegovic, J; Rienzi, N; Schachter, EN; Siegel, P; Wan, AE; Whitmer, M; Zuskin, E1
Camarasa, J; Camins, A; Canudas, AM; Escubedo, E; Pallàs, M; Pubill, D; Sureda, FX1
Eakin, AE; Eterović, VA; Ferchmin, PA; Lu, R; Rodríguez, AD1
Baubichon, D; Burckhart, MF; Carpentier, P; Filliat, P; Foquin, A; Lallement, G; Masqueliez, C; Pernot-Marino, I; Perrichon, C1
Bierman, EP; Bruijnzeel, PL; Carpentier, P; de Groot, DM; Kulig, BM; Lallement, G; Melchers, BP; Philippens, IH; van Huygevoort, AH1
Evenden, J1
Castranova, V; Gadgil, A; Goswami, S; Schachter, EN; Siegel, P; Whitmer, M; Zuskin, E1
CLARKE, HL; GOOL, RY1
YOUNG, FA1
HOFFMEISTER, F; KREISKOTT, H; WIRTH, W1

Reviews

1 review(s) available for atropine and phencyclidine

ArticleYear
The role of receptor binding in drug discovery.
    Journal of natural products, 1993, Volume: 56, Issue:4

    Topics: Animals; Drug Design; Humans; Receptors, Drug

1993

Other Studies

55 other study(ies) available for atropine and phencyclidine

ArticleYear
Activity of aromatic substituted phenylpiperazines lacking affinity for dopamine binding sites in a preclinical test of antipsychotic efficacy.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:5

    Topics: Animals; Antipsychotic Agents; Avoidance Learning; Dose-Response Relationship, Drug; Piperazines; Rats; Receptors, Dopamine; Receptors, Serotonin; Structure-Activity Relationship

1989
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Effects of phencyclidine, atropine and physostigmine, alone and in combination, on variable-interval performance in the squirrel monkey.
    Pharmacology, biochemistry, and behavior, 1979, Volume: 11, Issue:1

    Topics: Animals; Atropine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Haplorhini; Male; Phencyclidine; Physostigmine; Saimiri

1979
Occupational asthma due to California red wood (Sequoia sempervirens) dusts.
    The American review of respiratory disease, 1976, Volume: 114, Issue:5

    Topics: Asthma; Atropine; California; Cromolyn Sodium; Dust; Humans; Hypersensitivity, Immediate; Intradermal Tests; Lung; Lung Volume Measurements; Male; Middle Aged; Occupational Diseases; Occupations; Pneumoconiosis; Trees

1976
Phencyclidine ingestion: therapy review.
    Southern medical journal, 1977, Volume: 70, Issue:1

    Topics: Atropine; Child, Preschool; Diuretics; Humans; Kidney Function Tests; Liver Function Tests; Male; Naloxone; Phencyclidine; Respiration; Seizures

1977
A rapid method for measuring miotic activity of drugs in the intact mouse eye.
    Investigative ophthalmology, 1975, Volume: 14, Issue:2

    Topics: Amides; Animals; Arecoline; Atropine; Cholinesterase Inhibitors; Cyclopentanes; Dimethylamines; Drug Interactions; Lighting; Methods; Mice; Microscopy; Miotics; Mydriatics; Parasympathomimetics; Phencyclidine; Phenylacetates; Pupil; Pyridines; Time Factors

1975
Muscarinic antagonists attenuate dizocilpine-induced hypermotility in mice.
    Life sciences, 1992, Volume: 50, Issue:9

    Topics: Animals; Atropine; Dextroamphetamine; Dizocilpine Maleate; Male; Mice; Motor Activity; Parasympatholytics; Phencyclidine; Scopolamine

1992
The non-competitive NMDA antagonists MK-801 and PCP, as well as the competitive NMDA antagonist SDZ EAA494 (D-CPPene), interact synergistically with clonidine to promote locomotion in monoamine-depleted mice.
    Life sciences, 1990, Volume: 47, Issue:19

    Topics: Animals; Atropine; Clonidine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Male; Mice; Motor Activity; N-Methylaspartate; Phencyclidine; Piperazines; Receptors, N-Methyl-D-Aspartate

1990
N-methyl-D-aspartate receptors mediate activation of the c-fos proto-oncogene in a model of brain injury.
    Neuroscience, 1990, Volume: 35, Issue:2

    Topics: Animals; Anticonvulsants; Atropine; Brain; Brain Injuries; Dibenzocycloheptenes; Disease Models, Animal; Dizocilpine Maleate; DNA-Binding Proteins; Female; Gene Expression Regulation; Immunohistochemistry; Ketamine; Male; Nifedipine; Phencyclidine; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogenes; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter

1990
Dibenzocycloalkenimine (MK-801) stimulates phosphoinositide hydrolysis in rat cerebral cortical slices).
    Neuropharmacology, 1990, Volume: 29, Issue:8

    Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Atropine; Cerebral Cortex; Dizocilpine Maleate; Hydrolysis; In Vitro Techniques; Magnesium; Male; N-Methylaspartate; Phencyclidine; Phosphatidylinositols; Prazosin; Rats; Rats, Inbred Strains; Zinc

1990
Drug effects on the release of endogenous acetylcholine in vivo: measurement by intracerebral dialysis and gas chromatography-mass spectrometry.
    Journal of neurochemistry, 1990, Volume: 54, Issue:6

    Topics: Acetylcholine; Animals; Atropine; Chromatography, Gas; Consciousness; Corpus Striatum; Dialysis; Haloperidol; Magnesium; Male; Mass Spectrometry; Phencyclidine; Physostigmine; Piperidines; Potassium; Rats; Rats, Inbred Strains; Tetrodotoxin

1990
Effect of dopaminergic drugs on enhancement of the binding of quinuclidinyl benzilate by phencyclidine in vivo.
    Neuropharmacology, 1989, Volume: 28, Issue:6

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Atropine; Benzazepines; Dopamine; Dopamine Agents; Ergolines; Hydroxydopamines; Male; Mice; Mice, Inbred C57BL; Norepinephrine; Oxidopamine; Phencyclidine; Quinpirole; Quinuclidines; Quinuclidinyl Benzilate

1989
Spectral analysis of hippocampal EEG in the freely moving rat: effects of centrally active drugs and relations to evoked potentials.
    Electroencephalography and clinical neurophysiology, 1985, Volume: 60, Issue:1

    Topics: Anesthetics; Animals; Atropine; Electroencephalography; Evoked Potentials; Hippocampus; Movement; Parasympathomimetics; Phencyclidine; Phenobarbital; Physostigmine; Rats; Urethane

1985
Activation of lateral vestibular nucleus neurons by iontophoretically applied phencyclidine.
    Japanese journal of pharmacology, 1986, Volume: 42, Issue:1

    Topics: Acetylcholine; Animals; Atropine; Cats; Female; Glutamates; Glutamic Acid; Iontophoresis; Male; Neurons; Phencyclidine; Synapses; Vestibular Nuclei

1986
Behavioral effects of phencyclidine and ketamine alone and in combination with other drugs.
    European journal of pharmacology, 1987, Dec-15, Volume: 144, Issue:3

    Topics: Animals; Atropine; Atropine Derivatives; Behavior, Animal; Chlorpromazine; Dextroamphetamine; Drug Interactions; Ketamine; Male; Naloxone; Phencyclidine; Saimiri

1987
Effect of phencyclidine and two monohydroxy metabolites on 3H QNB binding in vivo in rats.
    Pharmacology, biochemistry, and behavior, 1987, Volume: 26, Issue:4

    Topics: Animals; Atropine; Brain; Male; Phencyclidine; Quinuclidines; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Tissue Distribution

1987
Effect of parenterally administered atropine on the percutaneous absorption of phencyclidine and methadone.
    Life sciences, 1985, Aug-05, Volume: 37, Issue:5

    Topics: Administration, Topical; Animals; Atropine; Dehydration; Injections, Intraperitoneal; Liver; Male; Methadone; Mice; Mice, Hairless; Phencyclidine; Skin

1985
Laboratory animal anaesthesia.
    Canadian Anaesthetists' Society journal, 1973, Volume: 20, Issue:5

    Topics: Amphibians; Anesthesia; Anesthesia, Conduction; Anesthesia, General; Animals; Animals, Laboratory; Anura; Atropine; Body Weight; Cardiac Output; Cats; Chloralose; Dogs; Fishes; Guinea Pigs; Haplorhini; Heart Rate; Hypnotics and Sedatives; Ketamine; Methods; Mice; Pentobarbital; Phencyclidine; Preanesthetic Medication; Rabbits; Rats; Reptiles; Thiopental

1973
The effects of some drugs on an evoked response sensitive to tetrahydrocannabinols.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 189, Issue:3

    Topics: Animals; Atropine; Blood Pressure; Brain; Cannabis; Cerebral Cortex; Chloralose; Chlorpromazine; Decerebrate State; Dextroamphetamine; Dronabinol; Electroencephalography; Ethanol; Evoked Potentials; Gallamine Triethiodide; Haplorhini; Lysergic Acid Diethylamide; Male; Mescaline; Methoxamine; Norepinephrine; Pentobarbital; Pentylenetetrazole; Phencyclidine; Picrotoxin; Strychnine

1974
Methods of anesthesia in nonhuman primates.
    Laboratory animal science, 1972, Volume: 22, Issue:6

    Topics: Anesthesia; Anesthesia, General; Anesthesia, Inhalation; Animals; Atropine; Benperidol; Body Temperature; Fentanyl; Halothane; Haplorhini; Infusions, Parenteral; Intubation, Intratracheal; Ketamine; Macaca; Pan troglodytes; Papio; Phencyclidine; Primates; Salivation; Thiamylal; Thiopental; Tranquilizing Agents

1972
Discriminative response control produced with hashish, tetrahydrocannabinols (delta 8-THC and delta 9-THC), and other drugs.
    Psychopharmacologia, 1974, Volume: 40, Issue:1

    Topics: Amphetamine; Animals; Atropine; Avoidance Learning; Cannabis; Chlordiazepoxide; Chlorpromazine; Choice Behavior; Cocaine; Cues; Diazepam; Discrimination, Psychological; Dronabinol; Ketamine; Levallorphan; Male; Morphine; Pentobarbital; Phencyclidine; Physostigmine; Psilocybin; Rats; Scopolamine; Transfer, Psychology; Yohimbine

1974
Parasympathetic nervous control of airway smooth muscle.
    Annals of the New York Academy of Sciences, 1974, Volume: 221

    Topics: Airway Resistance; Animals; Antigens; Atropine; Bronchi; Dogs; Dust; Histamine; Humans; Muscle, Smooth; Nerve Regeneration; Neurons, Efferent; Parasympathetic Nervous System; Receptors, Cholinergic; Respiratory System; Vagus Nerve

1974
The role of general anesthesia in experimental surgery on young minipigs.
    Journal of pediatric surgery, 1974, Volume: 9, Issue:4

    Topics: Anesthesia, Endotracheal; Animals; Animals, Laboratory; Atropine; Butyrophenones; Injections, Intramuscular; Intubation, Intratracheal; Phencyclidine; Piperazines; Preanesthetic Medication; Pyridines; Swine

1974
A detailed study of the cardiopulmonary response to ketamine and its blockade by atropine.
    Southern medical journal, 1970, Volume: 63, Issue:9

    Topics: Anesthetics; Animals; Atropine; Cardiac Catheterization; Cardiac Output; Cardiovascular System; Dogs; Dye Dilution Technique; Hemodynamics; Parasympatholytics; Phencyclidine; Piperidines; Respiration; Spirometry; Stimulation, Chemical; Sulfates; Vagus Nerve; Vasoconstrictor Agents

1970
Sedation and immobilisation of cattle in the field.
    The Veterinary record, 1971, Jun-26, Volume: 88, Issue:26

    Topics: Acepromazine; Analgesics; Animals; Atropine; Cattle; Immobilization; Injections, Intramuscular; Male; Morphinans; Phencyclidine; Succinylcholine; Tranquilizing Agents

1971
Byssinosis. Airway responses caused by inhalation of textile dusts.
    Archives of environmental health, 1971, Volume: 23, Issue:6

    Topics: Airway Resistance; Atropine; Byssinosis; Drug Synergism; Dust; Environmental Exposure; Histamine; Humans; Lung; Pneumoconiosis; Propranolol; Spirometry; Textile Industry

1971
A possible correlation between drug-induced hallucinations in man and a behavioural response in mice.
    Psychopharmacologia, 1967, Volume: 11, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Atropine; Behavior, Animal; Ergonovine; Hallucinations; Hallucinogens; Head; Humans; Lysergic Acid Diethylamide; Male; Mescaline; Methysergide; Mice; Phencyclidine; Phenethylamines; Psilocybin; Psychopharmacology; Scopolamine; Tic Disorders; Tryptamines; Yohimbine

1967
Action of psychotogenic drugs on single midbrain raphe neurons.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 171, Issue:2

    Topics: Animals; Atropine; Chlorpromazine; Hallucinogens; Lysergic Acid Diethylamide; Male; Mescaline; Mesencephalon; Methamphetamine; Neurons; Phencyclidine; Phenethylamines; Phenylalanine; Rats; Scopolamine; Tryptamines

1970
Behavioural effects of some morphine antagonists and hallucinogens in the rat.
    Nature, 1968, Nov-09, Volume: 220, Issue:5167

    Topics: Amphetamine; Analgesics; Anesthetics; Animals; Ataxia; Atropine; Azocines; Behavior, Animal; Cyclazocine; Levallorphan; Lysergic Acid Diethylamide; Male; Mescaline; Morphine; Motor Activity; Movement Disorders; Nalorphine; Narcotic Antagonists; Pentazocine; Phencyclidine; Piperidines; Psilocybin; Psychopharmacology; Rats

1968
Pharmacology of theta phase shift in the hippocampal CA1 region of freely moving rats.
    Electroencephalography and clinical neurophysiology, 1984, Volume: 58, Issue:5

    Topics: Anesthetics; Animals; Atropine; Electroencephalography; Hippocampus; Movement; Parasympathomimetics; Pentobarbital; Phencyclidine; Rats; Reserpine; Scopolamine; Urethane

1984
Interaction of phencyclidine with drugs affecting cholinergic neurotransmission.
    Neuropharmacology, 1980, Volume: 19, Issue:2

    Topics: Animals; Atropine; Dose-Response Relationship, Drug; Drug Interactions; Female; Male; Motor Activity; Parasympathetic Nervous System; Phencyclidine; Physostigmine; Rats; Synaptic Transmission

1980
Anorexia and hyperphagia produced by five pharmacologic classes of hallucinogens.
    Pharmacology, biochemistry, and behavior, 1982, Volume: 17, Issue:3

    Topics: Amphetamine; Animals; Anorexia; Atropine; Dextroamphetamine; Dogs; Dronabinol; Feeding and Eating Disorders; Feeding Behavior; Female; Hallucinogens; Humans; Lysergic Acid Diethylamide; Male; Phenazocine; Phencyclidine

1982
Multiple actions of phencyclidine: discriminant structure-activity relationships from molecular conformations and assay conditions.
    Federation proceedings, 1983, Volume: 42, Issue:9

    Topics: Animals; Atropine; Binding, Competitive; Brain; Hydrogen-Ion Concentration; Ion Channels; Kinetics; Molecular Conformation; Phencyclidine; Potassium; Receptors, Muscarinic; Structure-Activity Relationship

1983
The action of dust in the airways on secretion into the trachea of the cat.
    The Journal of physiology, 1983, Volume: 342

    Topics: Animals; Atropine; Cats; Dust; Female; Lung; Mucins; Propranolol; Secretory Rate; Trachea; Vagotomy; Vagus Nerve

1983
Effects of mecamylamine, nicotine, atropine and physostigmine on the phencyclidine-induced behavioral toxicity.
    Pharmacology, biochemistry, and behavior, 1984, Volume: 20, Issue:4

    Topics: Animals; Atropine; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions; Male; Mecamylamine; Mice; Motor Activity; Nicotine; Phencyclidine; Physostigmine; Seizures

1984
Antagonism of oxotremorine-induced behavioral suppression by antimuscarinic drugs.
    Psychopharmacology, 1981, Volume: 75, Issue:1

    Topics: Animals; Atropine; Atropine Derivatives; Behavior, Animal; Benztropine; Columbidae; Conditioning, Operant; Male; Meperidine; Oxotremorine; Parasympatholytics; Phencyclidine; Receptors, Muscarinic; Reinforcement Schedule; Scopolamine

1981
Effects of phencyclidine on the release of radioactivity from rat striatal slices labeled with [3H]choline.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 225, Issue:2

    Topics: Acetylcholine; Amphetamine; Animals; Atropine; Calcium; Choline; Corpus Striatum; Dose-Response Relationship, Drug; Ergolines; Male; Oxotremorine; Pergolide; Phencyclidine; Rats; Rats, Inbred Strains

1983
Reduction by atropine of phencyclidine hypertension and apneusis.
    Life sciences, 1982, Mar-15, Volume: 30, Issue:11

    Topics: Animals; Atropine; Blood Pressure; Heart Rate; Hypertension; Parasympathetic Nervous System; Phencyclidine; Rats; Rats, Inbred Strains; Respiration

1982
Phencyclidine: behavioral and biochemical evidence against the anticholinergic hypothesis.
    Pharmacology, biochemistry, and behavior, 1982, Volume: 17, Issue:1

    Topics: Animals; Atropine; Behavior, Animal; Brain; Drug Synergism; Male; Mice; Mice, Inbred ICR; Oxotremorine; Parasympatholytics; Phencyclidine; Quinuclidinyl Benzilate; Subcellular Fractions; Time Factors

1982
Anticonvulsant and antilethal effects of the phencyclidine derivative TCP in soman poisoning.
    Neurotoxicology, 1994,Winter, Volume: 15, Issue:4

    Topics: Animals; Anticonvulsants; Atropine; Electroencephalography; Guinea Pigs; Lethal Dose 50; Male; Phencyclidine; Pyridostigmine Bromide; Receptors, N-Methyl-D-Aspartate; Soman

1994
Modulation of soman-induced neuropathology with an anticonvulsant regimen.
    Neuroreport, 1994, Nov-21, Volume: 5, Issue:17

    Topics: Animals; Anticonvulsants; Atropine; Hippocampus; Male; Olfactory Pathways; Phencyclidine; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Seizures; Soman

1994
Coadministration of atropine, NBQX and TCP against soman-induced seizures.
    Neuroreport, 1994, May-09, Volume: 5, Issue:9

    Topics: Animals; Atropine; Drug Synergism; Electroencephalography; Male; Phencyclidine; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Seizures; Soman

1994
Pharmacologic characterization of wool dust extract in isolated guinea pig trachea.
    Environmental research, 1995, Volume: 69, Issue:2

    Topics: Air Pollutants, Occupational; Animals; Atropine; Bronchoconstriction; Calcium Channel Blockers; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Dust; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Indomethacin; Leukotriene Antagonists; Male; Occupational Exposure; Pyrilamine; Trachea; Verapamil; Wool

1995
Effects of recycled paper dust extracts on isolated guinea pig trachea.
    Lung, 1998, Volume: 176, Issue:1

    Topics: Animals; Atropine; Bronchial Spasm; Bronchitis; Bronchoconstriction; Bronchodilator Agents; Calcium Channel Blockers; Capsaicin; Conservation of Natural Resources; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Dust; Gallic Acid; Guinea Pigs; Histamine H1 Antagonists; Humans; Male; Muscle, Smooth; Paper; Pyrilamine; Trachea

1998
Assessment of the adrenergic effects of orphenadrine in rat vas deferens.
    The Journal of pharmacy and pharmacology, 1999, Volume: 51, Issue:3

    Topics: Adrenergic Agents; Animals; Atropine; Binding, Competitive; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Epididymis; Fluoxetine; In Vitro Techniques; Ligands; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Norepinephrine; Orphenadrine; Phencyclidine; Prazosin; Rats; Rats, Sprague-Dawley; Vas Deferens

1999
Determinants of phencyclidine potency on the nicotinic acetylcholine receptors from muscle and electric organ.
    Cellular and molecular neurobiology, 1999, Volume: 19, Issue:6

    Topics: Acetylcholine; Amino Acid Sequence; Amino Acid Substitution; Animals; Atropine; Binding Sites; Diterpenes; DNA, Complementary; Dose-Response Relationship, Drug; Electric Organ; Ion Channel Gating; Ion Channels; Kinetics; Mice; Molecular Sequence Data; Muscle Proteins; Muscle, Skeletal; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Nicotinic Antagonists; Patch-Clamp Techniques; Phencyclidine; Point Mutation; Protein Multimerization; Receptors, Nicotinic; Recombinant Fusion Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Torpedo; Xenopus laevis

1999
Memory impairment after soman intoxication in rat: correlation with central neuropathology. Improvement with anticholinergic and antiglutamatergic therapeutics.
    Neurotoxicology, 1999, Volume: 20, Issue:4

    Topics: Animals; Antidotes; Atropine; Behavior, Animal; Cholinergic Antagonists; Convulsants; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Male; Maze Learning; Memory Disorders; Neuroprotective Agents; Phencyclidine; Quinoxalines; Rats; Rats, Wistar; Soman; Spatial Behavior; Survival Rate; Time Factors

1999
Beneficial effects of TCP on soman intoxication in guinea pigs: seizures, brain damage and learning behaviour.
    Journal of applied toxicology : JAT, 2001, Volume: 21 Suppl 1

    Topics: Animals; Atropine; Behavior, Animal; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Discrimination Learning; Electroencephalography; Guinea Pigs; Male; Muscarinic Antagonists; Neuroprotective Agents; Phencyclidine; Pyridostigmine Bromide; Receptors, N-Methyl-D-Aspartate; Seizures; Soman

2001
The effects of psychotomimetics and psychomotor stimulants on two schedules promoting response switching in the rat.
    Psychopharmacology, 2002, Volume: 163, Issue:3-4

    Topics: Amphetamine; Amphetamines; Animals; Antipsychotic Agents; Atropine; Behavior, Animal; Caffeine; Central Nervous System Depressants; Central Nervous System Stimulants; Conditioning, Operant; Dose-Response Relationship, Drug; Ethanol; Food; Hallucinogens; Lysergic Acid Diethylamide; Muscarinic Antagonists; Phencyclidine; Photic Stimulation; Rats; Rats, Long-Evans; Reinforcement Schedule; Scopolamine

2002
Pharmacologic effects of tobacco dust extract on isolated Guinea pig trachea.
    Chest, 2003, Volume: 123, Issue:3

    Topics: Air Pollutants, Occupational; Animals; Atropine; Bronchoconstriction; Dose-Response Relationship, Drug; Dust; Endotoxins; Guinea Pigs; In Vitro Techniques; Male; Muscle, Smooth; Nicotiana; Plant Extracts; Trachea

2003
ANAESTHESIA FOR UNDER-DOCTORED AREAS. A TRIAL OF PHENCYCLIDINE IN NIGERIA.
    Anaesthesia, 1964, Volume: 19

    Topics: Anesthesia; Anesthesia, General; Anesthesia, Obstetrical; Anesthetics; Atropine; Child; Chlorpromazine; Female; Haloperidol; Humans; Meperidine; Nigeria; Obstetrics; Phencyclidine; Preanesthetic Medication; Pregnancy; Rural Health

1964
REFRACTION OF THE MONKEY EYE UNDER GENERAL ANESTHESIA.
    Vision research, 1963, Volume: 61

    Topics: Anesthesia; Anesthesia, General; Anesthetics; Animals; Atropine; Ether; Halothane; Haplorhini; Intraocular Pressure; Mydriatics; Pharmacology; Phencyclidine; Primates; Refraction, Ocular; Research; Thiopental

1963
[STUDIES WITH CENTRALLY ACTING ANTICHOLINERGICS].
    Arzneimittel-Forschung, 1964, Volume: 14

    Topics: Anesthetics; Animals; Atropine; Cats; Cholinergic Antagonists; Electroencephalography; Fishes; Guinea Pigs; Hallucinogens; Lysergic Acid Diethylamide; Mice; Parasympatholytics; Phencyclidine; Psychopharmacology; Rabbits; Rats

1964