Page last updated: 2024-09-05

atropine and phenacetin

atropine has been researched along with phenacetin in 19 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(phenacetin)
Trials
(phenacetin)
Recent Studies (post-2010) (phenacetin)
26,7111,2591,6972,37375162

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)phenacetin (IC50)
Cytochrome P450 1A2Homo sapiens (human)0.0287

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19908 (42.11)18.7374
1990's0 (0.00)18.2507
2000's5 (26.32)29.6817
2010's6 (31.58)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Duffy, EM; Jorgensen, WL1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Glen, RC; Lowe, R; Mitchell, JB1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Ganshorn, A; Kurz, H1
Boyd, EM2
Altland, K; Goedee, HW1
McClure, DA1
Guillory, JK; Hwang, SC; Lach, JL1
COLLIER, HO; SHORLEY, PG1
BUESSOW, H1
Barroso, M; Costa, S; Fonseca, S; Franco, J; Gameiro, R1

Reviews

2 review(s) available for atropine and phenacetin

ArticleYear
Encephalopathy in toxicity tests on laboratory animals.
    Archiv fur Toxikologie, 1971, Volume: 27, Issue:2

    Topics: Animals; Aspirin; Atropine; Behavior, Animal; Brain Damage, Chronic; Brain Diseases; Caffeine; Caseins; Cats; Diet; Dogs; Female; Leucomycins; Male; Mice; Organ Size; Penicillin G; Phenacetin; Pilocarpine; Rabbits; Rats; Starvation

1971
[Genetically dependent variability of drug effects].
    Medizinische Klinik, 1970, Aug-28, Volume: 65, Issue:35

    Topics: Anemia, Hemolytic; Anesthesia, General; Anesthetics; Animals; Antipyrine; Apnea; Atropine; Body Temperature; Coumarins; Cyanosis; Deficiency Diseases; Dexamethasone; Dogs; Drug Tolerance; Enzymes; Female; Glucosephosphate Dehydrogenase; Humans; Intraocular Pressure; Isonicotinic Acids; Male; Meperidine; Mice; Oxyphenbutazone; Pharmacogenetics; Phenacetin; Phenylbutazone; Phenytoin; Proteins; Rabbits; Rats; Succinylcholine

1970

Other Studies

17 other study(ies) available for atropine and phenacetin

ArticleYear
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
[Differences between the protein binding of newborns and adults and their importance for pharmacological action].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1968, Volume: 260, Issue:2

    Topics: Acetaminophen; Age Factors; Aminosalicylic Acids; Atropine; Chloramphenicol; Humans; Infant, Newborn; Isoniazid; Methicillin; Morphine; Nitrofurantoin; Oxyphenbutazone; Phenacetin; Phenobarbital; Phenytoin; Promethazine; Protein Binding; Salicylates; Sulfadimethoxine; Thiopental

1968
100-day LD 50 index of chronic toxicity.
    Clinical toxicology, 1971, Volume: 4, Issue:2

    Topics: Acetaminophen; Administration, Oral; Animals; Aspirin; Atropine; Caffeine; DDT; Drug-Related Side Effects and Adverse Reactions; Intubation, Gastrointestinal; Lethal Dose 50; Penicillin G; Phenacetin; Pilocarpine; Rats; Sodium Chloride; Sucrose; Time Factors

1971
The action of phenacetin on tremorine-induced cholinergic effects.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1969, Volume: 130, Issue:4

    Topics: Animals; Atropine; Diarrhea; Drug Synergism; Injections, Intraperitoneal; Mice; Parasympathetic Nervous System; Phenacetin; Proadifen; Salivation; Tremor; Tremorine

1969
Interactions between pharmaceutical compounds by thermal methods.
    Journal of pharmaceutical sciences, 1969, Volume: 58, Issue:3

    Topics: Acetaminophen; Aspirin; Atropine; Bile Acids and Salts; Caffeine; Drug Compounding; Drug Incompatibility; Drug Stability; Methods; Phenacetin; Phenobarbital; Phenytoin; Quinine; Temperature; Theophylline; Thermodynamics; Time Factors; Vitamin K

1969
Analgesic antipyretic drugs as antagonists of bradykinin.
    British journal of pharmacology and chemotherapy, 1960, Volume: 15

    Topics: Acetaminophen; Acetylcholine; Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyretics; Aspirin; Atropine; Bradykinin; Guinea Pigs; Histamine; Ileum; Kallikreins; Lysergic Acid Diethylamide; Morphine; Phenacetin; Phthalic Acids; Rats; Serotonin

1960
[ON THE PROBLEM OF PSYCHOSES DUE TO ANTIASTHMATIC DRUGS].
    Der Nervenarzt, 1964, Volume: 35

    Topics: Anti-Asthmatic Agents; Antipyrine; Asthma; Atropine; Caffeine; Digitalis Glycosides; Ephedrine; Hallucinations; Humans; Lobelia; Mental Disorders; Paranoid Disorders; Phenacetin; Psychoses, Substance-Induced; Psychotic Disorders; Strophanthins; Toxicology

1964
Toxicological analysis of cocaine adulterants in blood samples.
    Forensic science international, 2019, Volume: 299

    Topics: Atropine; Cocaine; Drug Contamination; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyzine; Ketamine; Lidocaine; Narcotics; Phenacetin; Tetramisole

2019