atropine has been researched along with perphenazine in 33 studies
| Studies (atropine) | Trials (atropine) | Recent Studies (post-2010) (atropine) | Studies (perphenazine) | Trials (perphenazine) | Recent Studies (post-2010) (perphenazine) |
|---|---|---|---|---|---|
| 26,711 | 1,259 | 1,697 | 1,666 | 243 | 128 |
| Protein | Taxonomy | atropine (IC50) | perphenazine (IC50) |
|---|---|---|---|
| ubiquitin-conjugating enzyme E2 N | Homo sapiens (human) | 14.79 | |
| Aldehyde oxidase 1 | Mus musculus (house mouse) | 6.1 | |
| Retinal dehydrogenase 1 | Homo sapiens (human) | 0.5242 | |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | 4.216 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.0003 | |
| Pleiotropic ABC efflux transporter of multiple drugs | Saccharomyces cerevisiae S288C | 1.4 | |
| Aldehyde oxidase | Homo sapiens (human) | 0.033 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 4.216 | |
| Aldehyde oxidase 1 | Macaca fascicularis (crab-eating macaque) | 3.6 | |
| Nuclear receptor subfamily 3 group C member 3 | Bos taurus (cattle) | 4.216 | |
| Aldehyde oxidase 1 | Rattus norvegicus (Norway rat) | 0.74 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (54.55) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (24.24) | 29.6817 |
| 2010's | 7 (21.21) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Duffy, EM; Jorgensen, WL | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Boliston, TA | 1 |
| Gala, RR; Jaques, S; Peters, JA; Subramanian, MG | 1 |
| Hrádková, M; Kupka, J | 1 |
| Färber, G; Fraling, F; Herz, A; Niedner, I | 1 |
| Del Rio, J; Fuentes, JA | 1 |
| Kamei, C; Shimomura, K; Ueki, S | 1 |
| David, JM; el-Yousef, MK; Janowsky, DS; Serkerke, HJ | 1 |
| Mereto, GC | 1 |
| Lauer, RM; Mueller, S; Roberts, RJ | 1 |
| Cates, LA; Cramer, MB; Gallio, RL | 1 |
| Frigerio, G | 1 |
| Elliott, RC | 1 |
| Haas, H; Jantos, W | 1 |
| Fujimori, M; Hayashi, A; Nakamura, K; Okuma, T | 1 |
| FUDEMA, JJ; PRABHU, VG; PROCTOR, CD; RIDLON, SA | 1 |
| ABREU, BE; RAHDERT, E; RICHARDS, AB; WEAVER, LC | 1 |
| TANAKA, M | 1 |
| CLARKE, RS; DUNDEE, JW; LOVE, WJ; MOORE, J; NICHOLL, RM | 1 |
1 review(s) available for atropine and perphenazine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 trial(s) available for atropine and perphenazine
| Article | Year |
|---|---|
Combined anticholinergic agents and atropine-like delirium.
Topics: Antidepressive Agents; Antiparkinson Agents; Atropine; Benztropine; Clinical Trials as Topic; Delirium; Drug Combinations; Humans; Memory Disorders; Parasympatholytics; Perphenazine; Placebos; Psychoses, Substance-Induced | 1972 |
[Double-blind controlled trial on treatment of psychosomatic syndromes by a new tranquilizer combination].
Topics: Adolescent; Adult; Affective Symptoms; Atropine; Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Drug Synergism; Female; Gastrointestinal Diseases; Headache; Humans; Male; Middle Aged; Pain; Perphenazine; Psychophysiologic Disorders; Sleep Wake Disorders; Tranquilizing Agents | 1974 |
30 other study(ies) available for atropine and perphenazine
| Article | Year |
|---|---|
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Letter: Side-effects of perphenazine.
Topics: Atropine; Humans; Nausea; Perphenazine; Postoperative Complications | 1975 |
Influence of cholinergic receptor blockade on drug-induced prolactin release in the monkey.
Topics: Animals; Atropine; Female; Haplorhini; Macaca; Perphenazine; Prolactin; Receptors, Cholinergic; Serotonin; Thyrotropin-Releasing Hormone | 1976 |
[Acute poisoning and intolerance of phenothiazine compounds of the piperazine type].
Topics: Adolescent; Adult; Antipsychotic Agents; Atropine; Child; Drug Hypersensitivity; Drug Incompatibility; Female; Humans; Male; Perphenazine; Poisoning; Scopolamine; Sleep Wake Disorders; Spasm; Suicide; Tachycardia | 1973 |
Pharmacologically induced alterations of cortical and subcortical evoked potentials compared with physiological changes during the awake-sleep cycle in cats.
Topics: Amphetamine; Anesthetics; Animals; Atropine; Auditory Cortex; Caffeine; Cats; Central Nervous System Stimulants; Cerebral Cortex; Chloralose; Chlorpromazine; Computers; Dihydroxyphenylalanine; Electroencephalography; Evoked Potentials; Hippocampus; Imipramine; Lysergic Acid Diethylamide; Pentobarbital; Perphenazine; Physostigmine; Sleep; Thalamus; Tranquilizing Agents; Visual Cortex; Wakefulness | 1967 |
Further studies on the antagonism of stereotyped behaviour induced by amphetamine.
Topics: Amphetamine; Animals; Atropine; Behavior, Animal; Benperidol; Chlorpromazine; Exploratory Behavior; Haloperidol; Male; Perphenazine; Phenothiazines; Phenoxybenzamine; Phentolamine; Pilocarpine; Promazine; Propranolol; Rats; Thioridazine; Tremorine; Trifluperidol | 1969 |
Significance of withdrawal jumping response in predicting physical dependence in mice.
Topics: Amitriptyline; Animals; Atropine; Cannabis; Chlordiazepoxide; Chlorpromazine; Diazepam; Humans; Imipramine; Male; Mephenesin; Methamphetamine; Mice; Morphine Dependence; Naloxone; Pentobarbital; Perphenazine; Phenytoin; Reserpine; Substance Withdrawal Syndrome | 1973 |
Propranolol in the treatment of cardiac arrhythmias associated with amitriptyline intoxication.
Topics: Amitriptyline; Arrhythmias, Cardiac; Atropine; Child, Preschool; Electrocardiography; Female; Humans; Injections, Intravenous; Perphenazine; Propranolol | 1973 |
Phosphorus--nitrogen compounds. XV. N-1-adamantylphosphoramidic dichloride and dimethyl and diphenyl N-1-adamantylphosphoramidate.
Topics: Amantadine; Animals; Antiparkinson Agents; Atropine; Guinea Pigs; Leukemia L1210; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred Strains; Motor Activity; Organophosphorus Compounds; Oxotremorine; Perphenazine; Spectrophotometry, Infrared; Tremorine | 1973 |
[Phentonium plus perphenazine?].
Topics: Adolescent; Adult; Affective Symptoms; Analysis of Variance; Anxiety; Atropine; Biphenyl Compounds; Computers; Drug Evaluation; Drug Synergism; Drug Tolerance; Dyspepsia; Female; Humans; Male; Middle Aged; Nausea; Perphenazine; Phenylacetates; Sleep Wake Disorders; Tranquilizing Agents; Vomiting | 1974 |
Centrally active drugs and the medullary vasopressor response of the cat; a method of distinguishing between drug actions on the central and peripheral parts of the sympathetic nervous system.
Topics: Adrenalectomy; Animals; Atropine; Benactyzine; Blood Pressure; Carbamates; Cats; Chlorpromazine; Dextrans; Electric Stimulation; Femoral Artery; Hydroxyzine; Medulla Oblongata; Methods; Perphenazine; Piperidines; Pressoreceptors; Prochlorperazine; Promazine; Sympathetic Nervous System; Temperature; Tranquilizing Agents | 1969 |
[Modification of central mechanisms of action by anticholinergics].
Topics: Aggression; Amphetamine; Animals; Apomorphine; Atropine; Biperiden; Bridged-Ring Compounds; Central Nervous System; Chlorpromazine; Depression, Chemical; Drug Synergism; Esters; Female; Hexobarbital; Humans; Imipramine; Male; Mice; Morphine; Nicotine; Parasympatholytics; Pentylenetetrazole; Perphenazine; Rats; Stimulation, Chemical; Strychnine; Tremorine | 1969 |
The effect of some psychotropic drugs on the electric activity of the brain and sleep cycle pattern of the cat.
Topics: Animals; Antidepressive Agents; Atropine; Brain; Cats; Chlordiazepoxide; Chlorpromazine; Electroencephalography; Electromyography; Electrooculography; Electrophysiology; Imipramine; Methotrimeprazine; Neostigmine; Pentobarbital; Perphenazine; Reserpine; Sleep; Tranquilizing Agents | 1967 |
EXTENSION OF TRANQUILIZER ACTION BY ANTICHOLINESTERASES.
Topics: Amphetamine; Atropine; Cholinesterase Inhibitors; Cholinesterases; Dextroamphetamine; Diphosphates; Enzyme Inhibitors; Hexobarbital; Hydrazines; Hypnotics and Sedatives; Iproniazid; Mice; Organophosphate Poisoning; Oximes; Parasympatholytics; Parathion; Perphenazine; Pharmacology; Phosphorus; Poisons; Pralidoxime Compounds; Pyridines; Research | 1964 |
EFFECT OF ANTIEMETICS AND OTHER COMPOUNDS ON PROTOVERATRINE INDUCED EMESIS IN DOGS.
Topics: Antiemetics; Atropine; Benzamides; Dogs; Haloperidol; Meclizine; Niacin; Perphenazine; Pharmacology; Prochlorperazine; Protoveratrines; Research; Triflupromazine; Veratrum; Vomiting | 1964 |
[EFFECTS OF VARIOUS AUTONOMIC NERVOUS DRUGS UPON EXCRETORY UROGRAMS. I. STUDIES ON INFLUENCES UPON VISIBILITIES AND SHAPES OF UROGRAMS, AND ALSO, ON THE CORRELATIONS BETWEEN THE AUTONOMIC NERVES IN URINARY TRACTS AND SYSTEMIC ONES].
Topics: Atropine; Autonomic Nervous System; Autonomic Pathways; Epinephrine; Neurotic Disorders; Perphenazine; Pharmacology; Pilocarpine; Rabbits; Research; Scopolamine; Theophylline; Urinary Calculi; Urography | 1964 |
STUDIES OF DRUGS GIVEN BEFORE ANAESTHESIA. VI. THE PHENOTHIAZINE DERIVATIVES.
Topics: Anesthesia; Anesthesia, General; Atropine; Chlorpromazine; Chlorprothixene; Fluphenazine; Humans; Meperidine; Methohexital; Methotrimeprazine; Nitrous Oxide; Oxygen; Perphenazine; Pharmacology; Phenothiazines; Preanesthetic Medication; Prochlorperazine; Promazine; Promethazine; Thiazines; Thiethylperazine; Toxicology; Tranquilizing Agents; Trifluoperazine; Triflupromazine; Trimeprazine | 1965 |