Page last updated: 2024-09-05

atropine and pergolide

atropine has been researched along with pergolide in 7 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(pergolide)
Trials
(pergolide)
Recent Studies (post-2010) (pergolide)
26,7111,2591,69784512387

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)pergolide (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.379
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)0.385
Alpha-2A adrenergic receptorHomo sapiens (human)0.264
Cytochrome P450 2D6Homo sapiens (human)0.2
D(2) dopamine receptorHomo sapiens (human)0.111
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.385
Alpha-2B adrenergic receptorHomo sapiens (human)0.064
Alpha-2C adrenergic receptorHomo sapiens (human)1.41
DRattus norvegicus (Norway rat)0.0031
D(3) dopamine receptorRattus norvegicus (Norway rat)0.0031
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.2
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)0.041
D(2) dopamine receptorBos taurus (cattle)0.0603
D(1A) dopamine receptorHomo sapiens (human)0.679
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)0.041
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)0.041
Alpha-1D adrenergic receptorHomo sapiens (human)1.513
D(1B) dopamine receptorRattus norvegicus (Norway rat)0.0031
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.014
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.379
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.2
5-hydroxytryptamine receptor 1DRattus norvegicus (Norway rat)0.385
D(4) dopamine receptorRattus norvegicus (Norway rat)0.0031
5-hydroxytryptamine receptor 1FRattus norvegicus (Norway rat)0.385
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)0.385
5-hydroxytryptamine receptor 6Rattus norvegicus (Norway rat)0.385
5-hydroxytryptamine receptor 7 Rattus norvegicus (Norway rat)0.385
5-hydroxytryptamine receptor 5ARattus norvegicus (Norway rat)0.385
5-hydroxytryptamine receptor 5BRattus norvegicus (Norway rat)0.385
D(3) dopamine receptorHomo sapiens (human)0.0054
5-hydroxytryptamine receptor 3ARattus norvegicus (Norway rat)0.385
Alpha-synucleinHomo sapiens (human)7.9
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.076
5-hydroxytryptamine receptor 6Homo sapiens (human)0.039
D(2) dopamine receptorRattus norvegicus (Norway rat)0.0031
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.1202
5-hydroxytryptamine receptor 4 Rattus norvegicus (Norway rat)0.385
DBos taurus (cattle)0.0603
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.385
5-hydroxytryptamine receptor 3BRattus norvegicus (Norway rat)0.385

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's1 (14.29)18.2507
2000's2 (28.57)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ahman, M; Holmén, AG; Wan, H1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jandhyala, BS; Kivlighn, SD; Lokhandwala, MF1
Johnson, KM; Leventer, SM1
Connell, TA; Weiss, B; Zhang, SP; Zhou, LW1
Prokopec, V; Švecová, M; Volochanskyi, O1

Reviews

1 review(s) available for atropine and pergolide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

6 other study(ies) available for atropine and pergolide

ArticleYear
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Characterization of the neurogenic vasodilatation elicited by central dopamine receptor stimulation with pergolide.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 228, Issue:3

    Topics: Animals; Antiparkinson Agents; Atropine; Blood Pressure; Brain; Dogs; Ergolines; Female; Hindlimb; Male; Norepinephrine; Pergolide; Receptors, Dopamine; Sulpiride; Sympathetic Nervous System; Vascular Resistance; Vasodilation

1984
Effects of phencyclidine on the release of radioactivity from rat striatal slices labeled with [3H]choline.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 225, Issue:2

    Topics: Acetylcholine; Amphetamine; Animals; Atropine; Calcium; Choline; Corpus Striatum; Dose-Response Relationship, Drug; Ergolines; Male; Oxotremorine; Pergolide; Phencyclidine; Rats; Rats, Inbred Strains

1983
AF64A lesions of mouse striatum result in ipsilateral rotations to D2 dopamine agonists but contralateral rotations to muscarinic cholinergic agonists.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:2

    Topics: Animals; Apomorphine; Atropine; Aziridines; Benzazepines; Choline; Corpus Striatum; Dopamine Agents; Functional Laterality; Male; Mice; Motor Activity; Neuromuscular Blocking Agents; Oxotremorine; Parasympathomimetics; Pergolide; Receptors, Dopamine D2; Receptors, Muscarinic; Rotation; Sulpiride

1993
Detection and identification of medically important alkaloids using the surface-enhanced Raman scattering spectroscopy.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2019, Jan-15, Volume: 207

    Topics: Adjuvants, Anesthesia; Atropine; Dopamine Agonists; Gold; Least-Squares Analysis; Pergolide; Silver; Spectrum Analysis, Raman

2019