atropine has been researched along with paraoxon in 68 studies
| Studies (atropine) | Trials (atropine) | Recent Studies (post-2010) (atropine) | Studies (paraoxon) | Trials (paraoxon) | Recent Studies (post-2010) (paraoxon) |
|---|---|---|---|---|---|
| 26,711 | 1,259 | 1,697 | 1,516 | 3 | 354 |
| Protein | Taxonomy | atropine (IC50) | paraoxon (IC50) |
|---|---|---|---|
| Fatty-acid amide hydrolase 1 | Mus musculus (house mouse) | 5.9 | |
| Carbonic anhydrase 1 | Homo sapiens (human) | 0.338 | |
| Carbonic anhydrase 2 | Homo sapiens (human) | 0.059 | |
| Cholinesterase | Homo sapiens (human) | 0.007 | |
| Acetylcholinesterase | Mus musculus (house mouse) | 0.013 | |
| Acetylcholinesterase | Homo sapiens (human) | 0.01 | |
| Carbonic anhydrase 13 | Mus musculus (house mouse) | 1.021 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (48.53) | 18.7374 |
| 1990's | 8 (11.76) | 18.2507 |
| 2000's | 9 (13.24) | 29.6817 |
| 2010's | 13 (19.12) | 24.3611 |
| 2020's | 5 (7.35) | 2.80 |
| Authors | Studies |
|---|---|
| Bleyer, H; Grisk, A; Möritz, KU | 1 |
| Dinnendahl, V; Stock, K | 1 |
| Haase, W; Vetterlein, F | 1 |
| Kullmann, R; Uerdingen, U | 1 |
| Choi, JJ; Pento, JT; Robinson, CP | 1 |
| Dettbarn, WD; Mobley, PL; Wecker, L | 1 |
| Bak, W; Borkowska, G; Faff, J | 1 |
| Abdallah, EA; Eldefrawi, AT; Eldefrawi, ME; Jett, DA | 1 |
| Ansay, M; Delaunois, A; Gustin, P | 1 |
| Bataillard, A; Blanchet, G; Sannajust, F; Sassard, J; Sentenac-Roumanou, H; Yoccoz, D | 1 |
| Domino, EF; Krutak-Krol, H | 1 |
| Nahas, G; Trouvé, R | 1 |
| König, A; Krügel, M; Oldiges, H; Schoene, K | 1 |
| Domino, EF | 1 |
| Cohen, Y; Coudray-Lucas, C; Le Guen, A; Prioux-Guyonneau, M; Wepierre, J | 1 |
| Goss, LB; Moore, MT; Reveley, JW; Sabourin, TD | 1 |
| Döda, M; György, L | 1 |
| Andersen, RA; Barstad, JA | 1 |
| Schmidt, J; Wolf, H | 1 |
| Patil, BG; Ramachandran, BV | 1 |
| Sakai, Y; Schmidt, G | 1 |
| Acara, M; Rennick, B | 1 |
| Dettbarn, WD; Hoekman, TB | 1 |
| Heering, H | 1 |
| Dierkes-Tizek, U; Glaser, U; Hettwer, H; Oldiges, H | 1 |
| Mitchelson, F; Ziegler, A | 1 |
| Bouchaud, C; de La Manche, I; Desroches, AM; Laget, P | 1 |
| Lüllmann, H; Schmaus, H; Staemmler, C; Ziegler, A | 1 |
| Amirmanssouri, M; Kullmann, R; Reinsberg, J | 1 |
| Klein, A; Klein, S | 1 |
| Schoene, K | 1 |
| Ehlert, FJ; Roeske, WR; Smit, MH; Yamamura, HI; Yamamura, S | 1 |
| Almog, S; Lifshitz, M; Rotenberg, M; Shahak, E; Sofer, S; Tamiri, T | 1 |
| Pei, L; Petrikovics, I; Way, JL | 1 |
| Calore, EE; Cavaliere, MJ; Perez, NM; Puga, FR | 1 |
| Radić, Z; Taylor, P | 1 |
| Dolezal, V; Tucek, S | 1 |
| Liu, XB; Martinez, JR; Sun, X; Zhang, GH | 1 |
| Chakraborti, T; Liu, J; Pope, C | 1 |
| Carvalho, FD; Guilhermino, L; Machado, I; Martínez, MS; Soares, A | 1 |
| Bowls, BJ; Freeman, JM; Luna, JA; Meggs, WJ | 1 |
| Baskin, SI; Cheng, TC; Hong, K; Jaszberenyi, JC; Jiang, J; Logue, BA; McGuinn, WD; Papahadjopoulos, D; Petrikovics, I; Szilasi, M; Way, JL | 1 |
| DE CANDOLE, CA; McPHAIL, MK | 1 |
| DECANDOLE, CA; McPHAIL, MK | 1 |
| HOBBIGER, F | 1 |
| ANDJELKOVIC, D; BINENFELD, Z; MILOSEVIC, M | 1 |
| Adler, M; Albuquerque, EX; Aracava, Y; Fawcett, WP; Hamilton, TA; Kan, RK; Oliveira, M; Pereira, EF; Randall, WR; Romano, JA | 1 |
| Kellar, KJ | 1 |
| Baud, FJ; Borron, SW; Garnier, R; Houze, P; Mégarbane, B; Monier, C; Risède, P; Sarhan, H; Villa, AF | 1 |
| Baud, FJ; Debray, M; Houze, P; Kayouka, M; Pronzola, L; Villa, A | 1 |
| Kapur, J; Kozhemyakin, M; Rajasekaran, K | 1 |
| Kawamata, M; Kawamata, T; Narimatsu, E; Niiya, T; Yamakage, M | 1 |
| Chávez, J; Cruz-Valderrama, JE; Montaño, LM; Vargas, MH | 1 |
| Carrasco, M; Cuadrado, BL; Eterović, VA; Ferchmin, PA; Martins, AH; Pérez, D | 1 |
| Abramochkin, DV; Borodinova, AA; Rosenshtraukh, LV | 1 |
| Daniels, D; Eisenkraft, A; Gilat, E; Kadar, T; Kapon, J; Krivoy, A; Last, D; Maier, S; Makarovski, I; Mardor, Y; Ramaty, E; Rosman, Y; Salomon, S; Schein, O; Shilderman, EB; Shneor, R; Shrot, S; Tamar, G | 1 |
| Balint, CA; Cowan, ML; Kapur, J; Sun, C; Todorovic, MS | 1 |
| Blair, RE; Carter, DS; DeLorenzo, RJ; Deshpande, LS; Phillips, KF | 1 |
| Bar-Klein, G; Biala, Y; Daninos, M; Friedman, A; Kamintsky, L; Kassirer, M; Krivoy, A; Lavon, O; Makarovsky, I; Ramaty, E; Rosman, Y; Shrot, S; Statlender, L; Yaari, Y | 1 |
| DeLorenzo, RJ; Deshpande, LS; Huang, B; Phillips, K | 1 |
| Cohen, Y; Eisenkraft, A; Kadar, T; Kassirer, M; Milk, N; Rosman, Y; Shiyovich, A; Shrot, S; Tauber, M | 1 |
| Thiermann, H; Wille, T; Worek, F | 1 |
| Al-Mansori, A; Al-Ramadi, BK; Bashir, G; Fernández-Cabezudo, MJ; George, JA; Lorke, DE; Mohamed, YA; Petroianu, G; Qureshi, MM | 1 |
| Harada, K; Inoue, H; Kakizaki, R; Kyan, R; Narimatsu, E; Nomura, K; Sawamoto, K; Uemura, S | 1 |
| Kassa, J; Kucera, T; Mzik, M; Sestak, V; Vecera, Z; Zdarova Karasova, J | 1 |
| Lenina, OA; Petrov, KA | 1 |
| Maksimović, ŽM; Škrbić, R; Stojiljković, MP | 1 |
| Narimatsu, E; Nomura, K; Oke, Y; Oku, Y | 1 |
68 other study(ies) available for atropine and paraoxon
| Article | Year |
|---|---|
[The effect of diisopropylfluorphosphate on the adenylate cyclase activity and the 3',5'-AMP content of myocardium and brain].
Topics: Adenylyl Cyclases; Animals; Atropine; Brain; Cyclic AMP; Dimethoate; Female; Heart; Isoflurophate; Male; Paraoxon; Rats | 1976 |
Effects of arecoline and cholinesterase inhibitors on cyclic guanosine 3',5'-monophosphate and adenosine 3'.5'-monophosphate in mouse brain.
Topics: Animals; Arecoline; Atropine; Brain; Brain Chemistry; Cerebellum; Cholinesterase Inhibitors; Cyclic AMP; Cyclic GMP; Diazepam; Male; Mice; MSH Release-Inhibiting Hormone; Paraoxon; Physostigmine | 1975 |
Regional blood flow determinations in the rat during paraoxon-poisoning and treatment with atropine and obidoxime.
Topics: Animals; Atropine; Blood Circulation; Male; Microspheres; Obidoxime Chloride; Oximes; Paraoxon; Rats; Regional Blood Flow | 1979 |
Regional pre- and postganglionic sympathetic activity during experimental paraoxon poisoning.
Topics: Animals; Atropine; Autonomic Fibers, Postganglionic; Autonomic Fibers, Preganglionic; Blood Pressure; Digestive System; Dose-Response Relationship, Drug; Female; Heart Rate; Hemodynamics; Kidney; Male; Muscles; Paraoxon; Rabbits; Spleen; Sympathetic Nervous System | 1978 |
Enhancement of intestinal glucose transport following chronic parathion poisoning.
Topics: Animals; Atropine; Biological Transport, Active; Calcium; Duodenum; Glucose; In Vitro Techniques; Male; Paraoxon; Parathion; Rats; Stimulation, Chemical; Time Factors | 1977 |
Effects of atropine on paraoxon-induced alterations in brain acetylcholine.
Topics: Acetylcholine; Animals; Atropine; Brain Chemistry; Chromatography, Gas; Drug Interactions; Male; Paraoxon; Rats; Time Factors | 1977 |
Therapeutic effects of some cholinolytics in organophosphate intoxications.
Topics: Animals; Antidotes; Atropine; Benzilates; Dichlorvos; Echothiophate Iodide; Isoflurophate; Lethal Dose 50; Mice; Muscle, Smooth; Organophosphate Poisoning; Oxotremorine; Paraoxon; Parasympatholytics; Piperidines; Rats | 1976 |
Differential effects of paraoxon on the M3 muscarinic receptor and its effector system in rat submaxillary gland cells.
Topics: Animals; Atropine; Binding Sites; Carbachol; Cyclic AMP; Hydrolysis; Male; Paraoxon; Phosphatidylinositols; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Regression Analysis; Submandibular Gland | 1992 |
Altered capillary filtration coefficient in parathion- and paraoxon-induced edema in isolated and perfused rabbit lungs.
Topics: Animals; Atropine; Biotransformation; Capillary Permeability; Capillary Resistance; Endothelium, Vascular; Female; Hemodynamics; In Vitro Techniques; Lung; Male; Nitrophenols; Organ Size; Paraoxon; Parathion; Perfusion; Piperonyl Butoxide; Pulmonary Circulation; Pulmonary Edema; Rabbits | 1992 |
Cardiovascular consequences of organophosphorus poisoning and of antidotes in conscious unrestrained rats.
Topics: Animals; Anti-Anxiety Agents; Antidotes; Atropine; Benzodiazepines; Benzodiazepinones; Blood Pressure; Diazepam; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Male; Organophosphate Poisoning; Paraoxon; Pralidoxime Compounds; Pyridostigmine Bromide; Rats; Rats, Inbred Strains; Soman | 1990 |
Comparative effects of diazepam and midazolam on paraoxon toxicity in rats.
Topics: Animals; Atropine; Benzodiazepines; Diazepam; Drug Interactions; Injections, Subcutaneous; Lethal Dose 50; Male; Midazolam; Paraoxon; Rats; Rats, Inbred Strains; Seizures | 1985 |
[A technic for selection of antidotes to an acute lethal poisoning].
Topics: Animals; Antidotes; Atropine; Diazepam; Male; Nimodipine; Paraoxon; Rats | 1988 |
Pharmacokinetics and efficacies of obidoxime and atropine in paraoxon poisoning.
Topics: Animals; Antidotes; Atropine; Chromatography, High Pressure Liquid; Female; Half-Life; Injections, Intravenous; Lethal Dose 50; Mice; Obidoxime Chloride; Oximes; Paraoxon | 1988 |
Comparative seizure inducing properties of various cholinesterase inhibitors: antagonism by diazepam and midazolam.
Topics: Animals; Atropine; Behavior, Animal; Cholinesterase Inhibitors; Diazepam; Isoflurophate; Male; Midazolam; Neostigmine; Paraoxon; Physostigmine; Pyridostigmine Bromide; Rats; Rats, Inbred Strains; Seizures | 1987 |
Changes in brain monoamine content and metabolism induced by paraoxon and soman intoxication. Effect of atropine.
Topics: Animals; Atropine; Behavior, Animal; Biogenic Amines; Brain; Chromatography, High Pressure Liquid; Male; Paraoxon; Rats; Rats, Inbred Strains; Soman | 1987 |
Distribution of neurotoxic esterase activity in the brain of control and diisopropyl phosphorofluoridate-treated hens: in vivo and in vitro exposure.
Topics: Animals; Atropine; Brain; Carboxylic Ester Hydrolases; Chickens; Drug Interactions; Female; Hydrolysis; Injections, Subcutaneous; Isoflurophate; Paraoxon; Physostigmine | 1986 |
Effect of cholinesterase inhibitors on the susceptibility to pentetrazole of the mouse.
Topics: Animals; Atropine; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Female; Male; Mecamylamine; Mice; Neostigmine; Oxotremorine; Paraoxon; Pentylenetetrazole; Physostigmine; Seizures; Tranylcypromine | 1974 |
Passage of tertiary and quaternary nitrogen compounds through the rat placenta.
Topics: Acetylcholinesterase; Animals; Atropine; Cholinesterase Inhibitors; Enzyme Activation; Erythrocytes; Female; Fetus; Maternal-Fetal Exchange; Nitrogen; Nitroso Compounds; Obidoxime Chloride; Oximes; Paraoxon; Placenta; Pralidoxime Compounds; Pregnancy; Pyridinium Compounds; Rats | 1974 |
[Influence of atropine and cholinesterase inhibitors on brain potentials caused by dental pulp stimulation].
Topics: Animals; Atropine; Brain; Cholinesterase Inhibitors; Dental Pulp; Electric Stimulation; Evoked Potentials; Female; Galantamine; Isoflurophate; Male; Paraoxon; Physostigmine; Rabbits | 1972 |
Effect of diisopropyl phosphorofluoridate & paraoxon in vivo & in vitro on the sodium & potassium contents of mouse liver tissue.
Topics: Acetylcholine; Animals; Atropine; In Vitro Techniques; Insecticides; Isoflurophate; Liver; Mice; Ouabain; Paraoxon; Physostigmine; Potassium; Sodium; Water | 1972 |
[Different effects of organophosphorus compounds Paraoxon and Soman on the discharge rate in single fibers of the rat phrenic nerve].
Topics: Animals; Atropine; Cholinesterase Inhibitors; Insecticides; Male; Neural Conduction; Neurons; Paraoxon; Phrenic Nerve; Rats; Soman | 1973 |
Renal tubular transport of acetylcholine and atropine: enhancement an inhibition.
Topics: Acetates; Acetylcholine; Alkenes; Animals; Atropine; Benzoxazoles; Biological Transport, Active; Carbon Isotopes; Chickens; Choline; Cholinesterase Inhibitors; Chromatography, Paper; Cocaine; Coloring Agents; Depression, Chemical; Electrophoresis; Female; Kidney Tubules; Kinetics; Paraoxon; Physostigmine; Quinine; Stimulation, Chemical; Tritium | 1972 |
Acetylcholine--a possible mechanism for the depolarization response in giant axons of the lobster circumesophageal connective.
Topics: Acetylcholine; Action Potentials; Animals; Atropine; Axons; Bromides; Choline; Cholinesterase Inhibitors; Drug Antagonism; Echothiophate Iodide; Electric Stimulation; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Membrane Potentials; Methacholine Compounds; Nephropidae; Neuromuscular Depolarizing Agents; Organophosphorus Compounds; Paraoxon; Physostigmine; Pralidoxime Compounds; Receptors, Cholinergic; Seawater; Tubocurarine | 1971 |
[The EGG during paraoxon poisoning of rats under the influence of atropine and pralidoxime (2-PAM)].
Topics: Animals; Atropine; Electrocardiography; Female; Heart Block; Heart Rate; Organophosphorus Compounds; Paraoxon; Pralidoxime Compounds; Rats; Respiratory Paralysis; Urethane | 1970 |
[The effect of organophosphates on heart ATPase in the rat].
Topics: Adenosine Triphosphatases; Animals; Antidotes; Atropine; Ca(2+) Mg(2+)-ATPase; Calcium-Transporting ATPases; Electrophysiology; Female; Isoflurophate; Kinetics; Myocardium; Obidoxime Chloride; Organophosphate Poisoning; Organophosphorus Compounds; Paraoxon; Parathion; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase | 1984 |
The effect of gallamine, gallopamil and nifedipine on responses to acetylcholine and carbachol in the taenia of the guinea-pig caecum.
Topics: Acetylcholine; Animals; Atropine; Calcium; Carbachol; Cecum; Drug Interactions; Gallamine Triethiodide; Gallopamil; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Nifedipine; Paraoxon; Time Factors; Verapamil | 1984 |
[Electrocorticograms and the histochemical effects in the rat accompanying the reactivation of cholinesterases after the effects of an organophosphorus inhibitor].
Topics: Animals; Atropine; Brain; Cerebral Cortex; Cholinesterases; Electroencephalography; Female; Male; Oximes; Paraoxon; Rats | 1980 |
Comparison of atropine and dexetimide in treatment of intoxications by selected organophosphates.
Topics: Animals; Atropine; Dexetimide; Diet; Guinea Pigs; Insecticides; Isoflurophate; Lethal Dose 50; Mice; Obidoxime Chloride; Organophosphate Poisoning; Organophosphorus Compounds; Paraoxon; Piperidines | 1982 |
Regional blood flow during paraoxon infusion in rabbits.
Topics: Animals; Atropine; Blood Circulation; Blood Pressure; Female; Male; Paraoxon; Rabbits; Regional Blood Flow; Renal Circulation; Skin; Splanchnic Circulation; Spleen; Sympathetic Nervous System; Vascular Resistance | 1982 |
[Postmortem pupil reaction to pharmacological and electrical stimulation].
Topics: Atropine; Electric Stimulation; Humans; Iris; Miotics; Mydriatics; Paraoxon; Time Factors | 1982 |
Pyridinium salts as organophosphate antagonists.
Topics: Atropine; Cholinesterase Inhibitors; Kinetics; Paraoxon; Pyridinium Compounds; Soman; Structure-Activity Relationship | 1980 |
Differential regulation of muscarinic agonist binding sites following chronic cholinesterase inhibition.
Topics: Animals; Atropine; Cholinesterase Inhibitors; Clonidine; Male; Paraoxon; Quinuclidinyl Benzilate; Rats; Receptors, Cholinergic; Receptors, Muscarinic | 1980 |
Carbamate poisoning and oxime treatment in children: a clinical and laboratory study.
Topics: Aldicarb; Antidotes; Atropine; Carbamates; Child; Child, Preschool; Cholinesterases; Drug Therapy, Combination; Female; Humans; Infant; Male; Methomyl; Obidoxime Chloride; Oximes; Paraoxon; Poisoning; Pralidoxime Compounds; Retrospective Studies | 1994 |
Antagonism of the lethal effects of paraoxon by carrier erythrocytes containing phosphotriesterase.
Topics: Animals; Antidotes; Aryldialkylphosphatase; Atropine; Cholinesterases; Dose-Response Relationship, Drug; Drug Carriers; Drug Combinations; Erythrocytes; Esterases; Insecticides; Male; Mice; Mice, Inbred BALB C; Mortality; Paraoxon; Pralidoxime Compounds; Survival; Time Factors | 1995 |
[Organophosphate-induced myotoxicity].
Topics: Animals; Atropine; Cholinesterase Reactivators; Cholinesterases; Diaphragm; Female; Insecticides; Male; Muscle Fibers, Skeletal; Paraoxon; Pralidoxime Compounds; Rats; Rats, Wistar | 1996 |
The influence of peripheral site ligands on the reaction of symmetric and chiral organophosphates with wildtype and mutant acetylcholinesterases.
Topics: Acetylation; Acetylcholinesterase; Alkaloids; Animals; Atropine; Binding Sites; Cholinesterase Inhibitors; Coumarins; Dichlorvos; Gallamine Triethiodide; Isoquinolines; Kinetics; Ligands; Mice; Mutagenesis, Site-Directed; Organophosphates; Organophosphorus Compounds; Paraoxon; Phosphorylation; Propidium; Stereoisomerism; Umbelliferones | 1999 |
Calcium channels involved in the inhibition of acetylcholine release by presynaptic muscarinic receptors in rat striatum.
Topics: Acetylcholine; Animals; Atropine; Calcium Channel Blockers; Calcium Channels; Carbachol; Cholinesterase Inhibitors; Domperidone; Dopamine Antagonists; Haloperidol; In Vitro Techniques; Male; Muscarinic Agonists; Muscarinic Antagonists; Neostriatum; omega-Agatoxin IVA; omega-Conotoxin GVIA; Paraoxon; Peptides; Rats; Receptors, Muscarinic; Receptors, Presynaptic; Spider Venoms | 1999 |
Effects of low concentrations of paraoxon on Ca(2+) mobilization in a human parotid salivary cell-line HSY.
Topics: Acetylcholine; Adenosine Triphosphate; Analysis of Variance; Atropine; Bacterial Proteins; Calcium Signaling; Calcium-Transporting ATPases; Cell Line; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Inositol 1,4,5-Trisphosphate; Insecticides; Muscarinic Antagonists; Paraoxon; Parotid Gland; Phosphatidylinositols; Purinergic P2 Receptor Agonists; Receptors, Muscarinic; Signal Transduction; Streptolysins; Thapsigargin | 2000 |
In vitro effects of organophosphorus anticholinesterases on muscarinic receptor-mediated inhibition of acetylcholine release in rat striatum.
Topics: Acetylcholine; Animals; Atropine; Chlorpyrifos; Cholinesterase Inhibitors; Corpus Striatum; Insecticides; Male; Muscarinic Antagonists; Paraoxon; Physostigmine; Potassium; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic | 2002 |
Use of atropine-treated Daphnia magna survival for detection of environmental contamination by acetylcholinesterase inhibitors.
Topics: Animals; Atropine; Biomarkers; Cholinesterase Inhibitors; Daphnia; Muscarinic Antagonists; Paraoxon; Survival; Water Pollutants, Chemical | 2003 |
Oral treatment of organophosphate poisoning in mice.
Topics: Animals; Antidotes; Atropine; Insecticides; Male; Mice; Mice, Inbred BALB C; Muscarinic Antagonists; Paraoxon; Parasympatholytics; Pralidoxime Compounds | 2003 |
Comparing therapeutic and prophylactic protection against the lethal effect of paraoxon.
Topics: Animals; Antidotes; Aryldialkylphosphatase; Atropine; Cholinesterase Reactivators; Drug Combinations; Insecticides; Lethal Dose 50; Liposomes; Male; Mice; Mice, Inbred BALB C; Muscarinic Antagonists; Neurotoxicity Syndromes; Paraoxon; Pralidoxime Compounds | 2004 |
Pentamethonium as an adjuvant to atropine in the therapy of paraoxon poisoning.
Topics: Adjuvants, Immunologic; Atropine; Bis-Trimethylammonium Compounds; Muscle Relaxants, Central; Organophosphate Poisoning; Paraoxon; Phosphates | 1954 |
Sarin and paraoxon antagonism in different.
Topics: Atropine; Autonomic Agents; Bis-Trimethylammonium Compounds; Cholinesterase Inhibitors; Humans; Paraoxon; Parathion; Phosphates; Sarin | 1957 |
Protection against the lethal effects of organophosphates by pyridine-2-aldoxime methiodide.
Topics: Acetylcholinesterase; Animals; Atropine; Brain; Cholinesterases; Diphosphates; Mice; Organophosphates; Oximes; Paraoxon; Phosphates; Phosphorylation; Picolines; Pralidoxime Compounds | 1957 |
[EFFECT OF VARIOUS OXIMES DERIVED FROM 1-PHENYL, 1-BENZYL AND 1-PHENACYL PYRIDINE AND ANALOGUES OF 4-FORMYL PYRIDINE IN PARAOXON INTOXICATION].
Topics: Acetylcholinesterase; Atropine; Chlorides; Inorganic Chemicals; Mice; Miotics; Organophosphate Poisoning; Oximes; Paraoxon; Phosphorus; Poisons; Pyridines; Research; Toxicology | 1964 |
Effective countermeasure against poisoning by organophosphorus insecticides and nerve agents.
Topics: Acetylcholinesterase; Alkaloids; Animals; Atropine; Behavior, Animal; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Therapy, Combination; Galantamine; Guinea Pigs; Insecticides; Lethal Dose 50; Neurons; Organophosphate Poisoning; Organophosphorus Compounds; Paraoxon; Poisoning; Pyridostigmine Bromide; Sarin; Sesquiterpenes; Soman; Time Factors | 2006 |
Overcoming inhibitions.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Atropine; Benzodiazepines; Blood-Brain Barrier; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Drug Therapy, Combination; Galantamine; Guinea Pigs; Insecticides; Neurons; Neurotransmitter Agents; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Paraoxon; Pralidoxime Compounds; Pyridostigmine Bromide; Receptors, Cholinergic; Receptors, Muscarinic; Sarin; Seizures; Soman; Time Factors | 2006 |
Toxic doses of paraoxon alter the respiratory pattern without causing respiratory failure in rats.
Topics: Animals; Atropine; Blood Gas Analysis; Carbon Dioxide; Cholinesterases; Drug Interactions; Insecticides; Lethal Dose 50; Male; Muscarinic Antagonists; Oxygen; Paraoxon; Plethysmography, Whole Body; Random Allocation; Rats; Rats, Sprague-Dawley; Respiration; Respiratory Insufficiency | 2007 |
Ventilatory effects of low-dose paraoxon result from central muscarinic effects.
Topics: Analysis of Variance; Animals; Atropine; Atropine Derivatives; Blood-Brain Barrier; Body Temperature; Dose-Response Relationship, Drug; Injections, Subcutaneous; Insecticides; Male; Paraoxon; Parasympatholytics; Plethysmography, Whole Body; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Respiration; Respiratory Function Tests; Signal Transduction; Telemetry; Tidal Volume; Time Factors | 2008 |
Central cholinesterase inhibition enhances glutamatergic synaptic transmission.
Topics: Animals; Atropine; Bungarotoxins; Carbachol; Cholinergic Agonists; Cholinesterase Inhibitors; Excitatory Postsynaptic Potentials; Glutamates; Hippocampus; Models, Animal; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Paraoxon; Patch-Clamp Techniques; Receptors, Muscarinic; Synapses; Synaptic Transmission | 2010 |
Effects of atropine and pralidoxime on neuronal actions of paraoxon in rat hippocampal slices.
Topics: Animals; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Excitatory Postsynaptic Potentials; Hippocampus; Muscarinic Antagonists; Neurons; Organ Culture Techniques; Paraoxon; Patch-Clamp Techniques; Pralidoxime Compounds; Rats; Rats, Wistar; Synaptic Transmission | 2010 |
Non-quantal release of acetylcholine in guinea-pig airways: role of choline transporter.
Topics: Acetylcholine; Animals; Atropine; Calcium; Cation Transport Proteins; Cholinesterase Inhibitors; Electric Stimulation; Guinea Pigs; Hemicholinium 3; Hexamethonium; Male; Membrane Transport Proteins; Muscle Contraction; Muscle, Smooth; Neurons; omega-Conotoxin GVIA; Organophosphates; Paraoxon; Piperidines; Tetrodotoxin; Trachea; Vesicular Acetylcholine Transport Proteins | 2011 |
A cembranoid protects acute hippocampal slices against paraoxon neurotoxicity.
Topics: Acetylcholinesterase; Animals; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diterpenes; Dose-Response Relationship, Drug; Hippocampus; Male; Neuroprotective Agents; Paraoxon; Parasympatholytics; Pralidoxime Compounds; Rats; Rats, Sprague-Dawley | 2011 |
Effects of acetylcholinesterase inhibitor paraoxon denote the possibility of non-quantal acetylcholine release in myocardium of different vertebrates.
Topics: Acetylcholine; Animals; Atropine; Cholinesterase Inhibitors; Gadus morhua; Heart; Heart Atria; Heart Ventricles; Hemicholinium 3; In Vitro Techniques; Male; Myocardium; Paraoxon; Piperidines; Rana temporaria; Rats; Rats, Wistar; Vertebrates | 2012 |
Using MRI for the assessment of paraoxon-induced brain damage and efficacy of antidotal treatment.
Topics: Animals; Antidotes; Atropine; Brain; Brain Diseases; Cholinergic Antagonists; Cholinesterase Inhibitors; Cholinesterase Reactivators; GABA Modulators; Magnetic Resonance Imaging; Male; Midazolam; Obidoxime Chloride; Paraoxon; Rats; Rats, Sprague-Dawley; Scopolamine | 2012 |
Characterization of status epilepticus induced by two organophosphates in rats.
Topics: Animals; Anticonvulsants; Atropine; Brain; Diazepam; Electroencephalography; Isoflurophate; Male; Neurons; Paraoxon; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus | 2012 |
Development of status epilepticus, sustained calcium elevations and neuronal injury in a rat survival model of lethal paraoxon intoxication.
Topics: Animals; Anticonvulsants; Atropine; Brain; Calcium; Diazepam; Disease Models, Animal; Electroencephalography; Hippocampus; Male; Neurons; Organophosphate Poisoning; Paraoxon; Pralidoxime Compounds; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2014 |
Prevention of organophosphate-induced chronic epilepsy by early benzodiazepine treatment.
Topics: Animals; Antidotes; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Chronic Disease; Epilepsy; Midazolam; Muscarinic Agonists; Obidoxime Chloride; Paraoxon; Pesticides; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2014 |
Chronic behavioral and cognitive deficits in a rat survival model of paraoxon toxicity.
Topics: Anhedonia; Animals; Anxiety; Atropine; Behavior, Animal; Cognition Disorders; Depression; Diazepam; Male; Memory Disorders; Organophosphate Poisoning; Paraoxon; Pralidoxime Compounds; Rats; Rats, Sprague-Dawley; Recognition, Psychology | 2014 |
Early brain magnetic resonance imaging can predict short and long-term outcomes after organophosphate poisoning in a rat model.
Topics: Animals; Aspartic Acid; Atropine; Behavior, Animal; Brain; Brain Edema; Choline; Cholinesterase Reactivators; Cognition; Creatine; Disease Models, Animal; Drug Therapy, Combination; Early Diagnosis; Magnetic Resonance Imaging; Male; Maze Learning; Midazolam; Neuroprotective Agents; Obidoxime Chloride; Organophosphate Poisoning; Paraoxon; Predictive Value of Tests; Proton Magnetic Resonance Spectroscopy; Rats, Sprague-Dawley; Scopolamine; Time Factors; Weight Loss | 2015 |
Oximes in organophosphate poisoning: 60 years of hope and despair.
Topics: Acetylcholinesterase; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Erythrocytes; Humans; Kinetics; Organophosphate Poisoning; Oximes; Paraoxon | 2016 |
Involvement of Acetylcholine Receptors in Cholinergic Pathway-Mediated Protection Against Autoimmune Diabetes.
Topics: Acetylcholinesterase; Animals; Atropine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Female; GPI-Linked Proteins; Hyperglycemia; Insulin-Secreting Cells; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Muscarinic Antagonists; Nicotinic Antagonists; Paraoxon; Receptors, Muscarinic; Receptors, Nicotinic; Streptozocin | 2019 |
Mechanism of central hypopnoea induced by organic phosphorus poisoning.
Topics: Animals; Atropine; Brain; Organophosphate Poisoning; Paraoxon; Pralidoxime Compounds; Rats; Respiratory Burst; Sleep Apnea, Central | 2020 |
Interaction of Cucurbit[7]uril with Oxime K027, Atropine, and Paraoxon: Risky or Advantageous Delivery System?
Topics: Animals; Atropine; Blood-Brain Barrier; Bridged-Ring Compounds; Cholinesterase Reactivators; Computer Simulation; Imidazoles; Mice; Molecular Docking Simulation; Oximes; Paraoxon; Pyridinium Compounds | 2020 |
Balanced modulation of neuromuscular synaptic transmission via M1 and M2 muscarinic receptors during inhibition of cholinesterases.
Topics: Animals; Antidotes; Atropine; Cholinesterase Inhibitors; Cholinesterases; Diamines; Diaphragm; Disease Models, Animal; Mice; Muscarinic Antagonists; Muscle Contraction; Muscle Weakness; Paraoxon; Parasympatholytics; Pirenzepine; Protective Agents; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Signal Transduction; Synaptic Transmission; Treatment Outcome | 2022 |
Dose-Dependency of Toxic Signs and Outcomes of Paraoxon Poisoning in Rats.
Topics: Acetylcholinesterase; Animals; Atropine; Fasciculation; Paraoxon; Rats; Seizures; Tremor | 2022 |
The lesion site of organophosphorus-induced central apnea and the effects of antidotes.
Topics: Animals; Antidotes; Atropine; Neostigmine; Paraoxon; Pralidoxime Compounds; Pyridines; Rats; Rats, Sprague-Dawley; Sleep Apnea, Central | 2023 |