Page last updated: 2024-09-05

atropine and oxymetazoline

atropine has been researched along with oxymetazoline in 7 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(oxymetazoline)
Trials
(oxymetazoline)
Recent Studies (post-2010) (oxymetazoline)
26,7111,2591,697738128159

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)oxymetazoline (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.578
Muscarinic acetylcholine receptor M4Homo sapiens (human)3.261
Muscarinic acetylcholine receptor M5Homo sapiens (human)1.332
Alpha-2A adrenergic receptorHomo sapiens (human)0.023
Cytochrome P450 2D6Homo sapiens (human)0.2
Alpha-2B adrenergic receptorHomo sapiens (human)1.273
Alpha-2C adrenergic receptorHomo sapiens (human)2.633
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.0056
Alpha-1D adrenergic receptorHomo sapiens (human)2.844
5-hydroxytryptamine receptor 2AHomo sapiens (human)1.285
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.578
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.0056
5-hydroxytryptamine receptor 2BHomo sapiens (human)3.056
5-hydroxytryptamine receptor 6Homo sapiens (human)1.67

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's4 (57.14)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Kobinger, W; Pichler, L1
Baroody, FM; Jankowski, R; Naclerio, RM; Philip, G; Togias, AG1
Thrush, DN1
Brown, DR; Malone, ED; Trent, AM; Turner, TA1
De Los Angeles, J; Jagadeesh, JM; Jing, L; Miller, DD; Patil, PN1

Other Studies

7 other study(ies) available for atropine and oxymetazoline

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Investigation into some imidazoline compounds, with respect to peripheral alpha-adrenoceptor stimulation and depression of cardiovascular centers.
    Naunyn-Schmiedeberg's archives of pharmacology, 1975, Volume: 291, Issue:2

    Topics: Adrenergic alpha-Agonists; Animals; Atropine; Blood Pressure; Brain; Cats; Clonidine; Dogs; Female; Heart Rate; Imidazoles; Imidazolidines; Male; Naphazoline; Oxymetazoline; Pressoreceptors; Rats; Receptors, Adrenergic; Reflex; Vagotomy; Vagus Nerve; Vasomotor System; Xylazine

1975
Reflex activation of nasal secretion by unilateral inhalation of cold dry air.
    The American review of respiratory disease, 1993, Volume: 148, Issue:6 Pt 1

    Topics: Adult; Anesthesia, Local; Atropine; Cold Temperature; Double-Blind Method; Female; Humans; Humidity; Lidocaine; Male; Nasal Mucosa; Oxymetazoline; Random Allocation; Reflex; Respiration

1993
Cardiac arrest after oxymetazoline nasal spray.
    Journal of clinical anesthesia, 1995, Volume: 7, Issue:6

    Topics: Anti-Arrhythmia Agents; Atropine; Bradycardia; Cardiopulmonary Resuscitation; Child, Preschool; Endoscopy; Female; Heart Arrest; Humans; Hypertension; Nasal Cavity; Oxymetazoline; Sympathomimetics

1995
Influence of adrenergic and cholinergic mediators on the equine jejunum in vitro.
    American journal of veterinary research, 1996, Volume: 57, Issue:6

    Topics: Acetylcholine; Adrenergic Agonists; Adrenergic Antagonists; Animals; Atropine; Brimonidine Tartrate; Calcium Channel Blockers; Cholinergic Agonists; Cholinergic Antagonists; Dose-Response Relationship, Drug; Horses; Isoproterenol; Jejunum; Muscle Contraction; Muscle, Smooth; Norepinephrine; Oxymetazoline; Parasympathetic Nervous System; Phentolamine; Phenylephrine; Prazosin; Quinoxalines; Sympathetic Nervous System; Tetrodotoxin; Verapamil; Yohimbine

1996
Depolarization of membrane potential and the smooth muscle contraction by isothiocyanatobenzyl imidazoline in guinea-pig stomach circular muscle.
    Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 360, Issue:3

    Topics: Animals; Atropine; Carbachol; Cromakalim; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Nifedipine; Oxymetazoline; Stomach; Tolazoline; Vasodilator Agents

1999