atropine has been researched along with oxybutynin in 41 studies
| Studies (atropine) | Trials (atropine) | Recent Studies (post-2010) (atropine) | Studies (oxybutynin) | Trials (oxybutynin) | Recent Studies (post-2010) (oxybutynin) |
|---|---|---|---|---|---|
| 26,711 | 1,259 | 1,697 | 2,607 | 619 | 1,670 |
| Protein | Taxonomy | atropine (IC50) | oxybutynin (IC50) |
|---|---|---|---|
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 2.5951 | |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 0.027 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 0.002 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 0.0032 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 0.0035 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 0.0027 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 2.5951 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 0.6 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.4288 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.792 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 0.0855 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.0242 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (17.07) | 18.7374 |
| 1990's | 13 (31.71) | 18.2507 |
| 2000's | 13 (31.71) | 29.6817 |
| 2010's | 8 (19.51) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adams, TC; Audia, VH; Dupont, AC; Hatoum, H; Kaiser, C; Lowe, VC; Noronha-Blob, L; Prosser, JC; Spagnuolo, CJ; Sturm, BL | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Bhattacharjee, AK; Evans, SA; Gordon, RK; Pervitsky, D; Pomponio, JW | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Bissada, NK; Finkbeiner, AE; Welch, LT | 1 |
| Anderson, GF; Fredericks, CM; Kreulen, DL | 1 |
| Gomi, Y; Hashimoto, S; Ito, Y; Kato, H; Morikawa, K; Yamauchi, T | 1 |
| Deguchi, Y; Kumada, S; Ohtsuka, M; Terai, T | 1 |
| Kontani, H; Nakagawa, M; Sakai, T; Takeno, S | 1 |
| Chun, A; Kato, K; Kitada, S; Levin, RM; Wein, AJ | 1 |
| Hanson, RC; Noronha-Blob, L; Peterson, JS | 1 |
| Kasama, T; Mayuzumi, K; Tamaru, K; Watanabe, K | 1 |
| Fujii, Y; Hosokawa, T; Kamei, J; Kasama, T; Misawa, M; Uehara, M; Watanabe, K; Yanaura, S | 1 |
| Levin, RM; Wein, AJ | 1 |
| Ukimura, O | 1 |
| Kondo, S; Morita, T | 1 |
| Andersson, KE; Larsson, B; Waldeck, K | 1 |
| Andersson, KE; Gillberg, PG; Nilvebrant, L; Sparf, B; Stahl, M | 1 |
| Hamada, K; Kimura, K; Kimura, Y; Sasaki, Y; Seto, T; Ukai, Y; Yamazaki, C; Yoshikuni, Y | 1 |
| Kikukawa, H; Nishi, K; Ueda, S; Wada, Y; Yoshida, M | 1 |
| Kwak, TI; Lee, JG | 1 |
| Kaneko, S; Nakano, D; Nishimori, T; Ohara, M | 1 |
| Hirota, T; Isogai, M; Kaneko, S; Nagao, M; Shimizu, H | 1 |
| Fowler, CJ | 1 |
| Doi, T; Imai, S; Kamo, I; Okanishi, S | 1 |
| Daniels, DV; Eglen, RM; Ford, AP; Hegde, SS; Meloy, TD | 1 |
| Averbeck, B; Bräter, M; Ravens, U; Reif, S; Wüst, M | 1 |
| Hatanaka, T; Ikeda, K; Kobayashi, S; Miyata, K; Ohtake, A; Sasamata, M; Sato, S; Ukai, M | 1 |
| Chancellor, MB; de Miguel, F; Kim, Y; Masuda, H; Yoshimura, N | 1 |
| Pinna, C; Puglisi, L; Sanvito, P | 1 |
| Barton, R; Brooks, R; Fader, M; Glickman, S; Haggar, V; Malone-Lee, J | 1 |
| Hatanaka, T; Miyata, K; Noguchi, Y; Ohtake, A; Okutsu, H; Saitoh, C; Sasamata, M; Sato, S; Suzuki, M; Ukai, M; Yuyama, H | 1 |
| Chatterjee, M; Chugh, A; Dastidar, S; Gupta, D; Gupta, S; Nanda, K; Ray, A; Singh, RK; Sundaram, S; Tiwari, A | 1 |
| Chess-Williams, R; Moro, C; Uchiyama, J | 1 |
| Cho, Y; Ha, YC; Hur, GH; Kim, WS | 1 |
3 review(s) available for atropine and oxybutynin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Uropharmacology: part VI. Parasympathetic depressants.
Topics: Acetylcholine; Atropine; Belladonna Alkaloids; Benactyzine; Cyclohexanes; Hemicholinium 3; Humans; Male; Mandelic Acids; Muscle Contraction; Parasympatholytics; Propantheline; Quaternary Ammonium Compounds; Urethra; Urinary Bladder; Urinary Bladder, Neurogenic; Urination Disorders | 1977 |
Intravesical treatment of overactive bladder.
Topics: Administration, Intravesical; Anesthetics, Local; Atropine; Capsaicin; Cholinergic Antagonists; Diterpenes; Humans; Mandelic Acids; Neurons, Afferent; Neurotoxins; Urinary Bladder Diseases; Urinary Incontinence | 2000 |
1 trial(s) available for atropine and oxybutynin
| Article | Year |
|---|---|
Intravesical atropine compared to oral oxybutynin for neurogenic detrusor overactivity: a double-blind, randomized crossover trial.
Topics: Administration, Intravesical; Administration, Oral; Adult; Aged; Atropine; Cross-Over Studies; Double-Blind Method; Humans; Mandelic Acids; Middle Aged; Muscarinic Antagonists; Urinary Bladder, Neurogenic; Urinary Bladder, Overactive | 2007 |
37 other study(ies) available for atropine and oxybutynin
| Article | Year |
|---|---|
Synthesis and antimuscarinic properties of some N-substituted 5-(aminomethyl)-3,3-diphenyl-2(3H)-furanones.
Topics: Animals; Furans; Guinea Pigs; Male; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Rabbits; Receptors, Muscarinic; Structure-Activity Relationship | 1992 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Discovery of subtype selective muscarinic receptor antagonists as alternatives to atropine using in silico pharmacophore modeling and virtual screening methods.
Topics: Atropine; Computer Simulation; Drug Discovery; Humans; Models, Molecular; Molecular Structure; Receptor, Muscarinic M1; Structure-Activity Relationship | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
A study of the anticholinergic and antispasmodic activity of oxybutynin (Ditropan) on rabbit detrusor.
Topics: Animals; Atropine; Barium; Carbachol; Cyclohexanes; Diethylamines; Drug Evaluation, Preclinical; Histamine H1 Antagonists; Male; Mandelic Acids; Muscle, Smooth; Parasympatholytics; Propantheline; Quaternary Ammonium Compounds; Rabbits; Urinary Bladder | 1975 |
Inhibitory effect of inaperisone hydrochloride (inaperisone), a new centrally acting muscle relaxant, on the micturition reflex.
Topics: Anesthesia; Animals; Atropine; Baclofen; Brain; Male; Mandelic Acids; Muscle Contraction; Muscle Relaxants, Central; Parasympatholytics; Propiophenones; Rats; Rats, Inbred Strains; Reflex; Synaptosomes; Tritium; Urinary Bladder | 1992 |
Effects of the anticholinergic drug prifinium bromide on urinary bladder contractions in rat in vivo and in guinea-pig in vitro.
Topics: Animals; Atropine; Barium; Barium Compounds; Butylamines; Calcium Channel Blockers; Chlorides; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Mandelic Acids; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Parasympatholytics; Potassium Chloride; Pyrrolidines; Rats; Rats, Inbred Strains; Urinary Bladder | 1991 |
Evaluation of drugs for treatment of urinary bladder dysfunction in conscious rats with intact pelvic nerve and after resection of the left pelvic nerve.
Topics: Animals; Atropine; Butylamines; Decerebrate State; Drug Evaluation; Male; Mandelic Acids; Nifedipine; Parasympatholytics; Physostigmine; Rats; Rats, Inbred Strains; Urinary Bladder; Urinary Bladder Diseases | 1990 |
In vitro intravesical instillation of anticholinergic, antispasmodic and calcium blocking agents (rabbit whole bladder model).
Topics: Administration, Intravesical; Animals; Atropine; Bethanechol; Bethanechol Compounds; Calcium Channel Blockers; Imipramine; Male; Mandelic Acids; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Rabbits; Urinary Bladder; Urinary Bladder, Neurogenic | 1989 |
In vivo cystometrogram studies in urethane-anesthetized and conscious guinea pigs.
Topics: Anesthesia; Animals; Atropine; Cystoscopy; Female; Guinea Pigs; Mandelic Acids; Parasympatholytics; Stereoisomerism; Urethane; Urinary Bladder | 1989 |
[Effects of oxybutynin hydrochloride on the urinary bladder and urethra in in situ preparations].
Topics: Animals; Atropine; Cats; Drug Interactions; Female; Flavoxate; Hypogastric Plexus; Male; Mandelic Acids; Papaverine; Pelvis; Peripheral Nerves; Propantheline; Rabbits; Urethra; Urinary Bladder | 1986 |
[Effects of oxybutynin on the cardiovascular system in dogs].
Topics: Acetylcholine; Animals; Atropine; Coronary Circulation; Dogs; Drug Synergism; Electrocardiography; Female; Hemodynamics; Male; Mandelic Acids; Myocardial Contraction; Norepinephrine; Parasympatholytics; Renal Circulation; Respiration | 1984 |
Direct measurement of the anticholinergic activity of a series of pharmacological compounds on the canine and rabbit urinary bladder.
Topics: Animals; Atropine; Binding, Competitive; Dicyclomine; Dogs; Female; Glycopyrrolate; Imipramine; In Vitro Techniques; Mandelic Acids; Parasympatholytics; Propantheline; Rabbits; Radioligand Assay; Receptors, Cholinergic; Receptors, Muscarinic; Urinary Bladder | 1982 |
Effects of intravesically administered anticholinergics, beta-adrenergic stimulant and alpha-adrenergic blocker on bladder function in unanesthetized rats.
Topics: Administration, Intravesical; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Animals; Atropine; Isoproterenol; Male; Mandelic Acids; Parasympatholytics; Prazosin; Propantheline; Rats; Rats, Wistar; Urinary Bladder | 1993 |
[A study of muscarinic cholinergic receptor subtypes in human detrusor muscle using radioligand binding techniques].
Topics: Aged; Atropine; Female; Humans; Male; Mandelic Acids; Muscle, Smooth; Pirenzepine; Radioligand Assay; Receptors, Muscarinic; Urinary Bladder | 1993 |
Comparison of oxybutynin and its active metabolite, N-desethyl-oxybutynin, in the human detrusor and parotid gland.
Topics: Adult; Aged; Atropine; Carbachol; Humans; In Vitro Techniques; Mandelic Acids; Middle Aged; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Parotid Gland; Receptors, Muscarinic; Urinary Bladder | 1997 |
Tolterodine--a new bladder-selective antimuscarinic agent.
Topics: Adult; Aged; Analgesia; Animals; Atropine; Benzhydryl Compounds; Cats; CHO Cells; Cholinergic Antagonists; Cresols; Cricetinae; Dose-Response Relationship, Drug; Female; Guinea Pigs; Humans; Infusions, Intravenous; Mandelic Acids; Middle Aged; Muscarinic Antagonists; Muscle Contraction; Phenylpropanolamine; Salivation; Tolterodine Tartrate; Urinary Bladder | 1997 |
Effect of NS-21, an anticholinergic drug with calcium antagonistic activity, on lower urinary tract function in a rat model of urinary frequency.
Topics: Animals; Atropine; Benzilates; Calcium Channel Blockers; Denervation; Disease Models, Animal; Flavoxate; Hypogastric Plexus; Male; Mandelic Acids; Parasympatholytics; Phenylacetates; Rats; Rats, Sprague-Dawley; Urinary Bladder; Urinary Incontinence | 1997 |
Pharmacologic actions of temiverine (p-INN) and its active metabolite, RCC-36, on isolated human urinary bladder muscle.
Topics: Acetylcholine; Aged; Atropine; Calcium Channel Blockers; Calcium Chloride; Cholinergic Antagonists; Electric Stimulation; Female; Humans; In Vitro Techniques; Male; Mandelic Acids; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Phenylacetates; Potassium Chloride; Urinary Bladder | 1998 |
Inhibitory effects of propiverine, atropine and oxybutynin on bladder instability in rats with infravesical outlet obstruction.
Topics: Animals; Atropine; Benzilates; Female; Ligation; Mandelic Acids; Parasympatholytics; Pressure; Rats; Rats, Sprague-Dawley; Urethral Obstruction; Urinary Bladder Diseases; Urination | 1998 |
[Effects of propiverine hydrochloride (propiverine) on isolated rat and dog urinary bladder].
Topics: Acetylcholine; Animals; Atropine; Benzilates; Butylamines; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Female; In Vitro Techniques; Male; Mandelic Acids; Muscarinic Antagonists; Muscle Contraction; Parasympatholytics; Potassium Chloride; Propantheline; Rats; Rats, Wistar; Urinary Bladder; Urination; Urination Disorders; Vasodilator Agents; Verapamil | 1999 |
[Effects of propiverine hydrochloride (propiverine) on the muscarinic receptor binding affinity in guinea pig tissues and on salivation in conscious dogs].
Topics: Animals; Atropine; Benzilates; Binding, Competitive; Butylamines; Cerebral Cortex; Dogs; Dose-Response Relationship, Drug; Female; Guinea Pigs; Heart; Ileum; Male; Mandelic Acids; Muscarinic Agonists; Muscarinic Antagonists; Parasympatholytics; Pilocarpine; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Salivary Glands; Salivation; Urinary Bladder; Urination Disorders | 1999 |
Possible site of action of TAK-637, a tachykinin NK(1) receptor antagonist, on the micturition reflex in guinea pigs.
Topics: Animals; Atropine; Benzhydryl Compounds; Benzilates; Carbachol; Cresols; Denervation; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Humans; In Vitro Techniques; Male; Mandelic Acids; Muscle Contraction; Naphthyridines; Pelvis; Phenylpropanolamine; Reflex; Tolterodine Tartrate; Urinary Bladder; Urinary Bladder Diseases | 2000 |
Functional characterization of rat submaxillary gland muscarinic receptors using microphysiometry.
Topics: Alkaloids; Animals; Atropine; Benzhydryl Compounds; Benzodiazepinones; Binding, Competitive; Biosensing Techniques; Carbachol; Cholinergic Agonists; Cresols; Diamines; Dose-Response Relationship, Drug; Furans; Male; Mandelic Acids; Muscarinic Antagonists; Naphthalenes; Phenethylamines; Phenylpropanolamine; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Submandibular Gland; Tolterodine Tartrate | 2001 |
Different responses to drugs against overactive bladder in detrusor muscle of pig, guinea pig and mouse.
Topics: Animals; Atropine; Benzhydryl Compounds; Benzilates; Carbachol; Cholinergic Agonists; Cholinergic Antagonists; Cresols; Dose-Response Relationship, Drug; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Male; Mandelic Acids; Mice; Mice, Inbred C57BL; Muscle Contraction; Muscle, Smooth; Phenylpropanolamine; Species Specificity; Swine; Tolterodine Tartrate; Urinary Bladder | 2002 |
In vitro and in vivo tissue selectivity profile of solifenacin succinate (YM905) for urinary bladder over salivary gland in rats.
Topics: Animals; Atropine; Benzhydryl Compounds; Benzofurans; Calcium; Cresols; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Mandelic Acids; Muscarinic Antagonists; Myocytes, Smooth Muscle; Organ Specificity; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Rats; Rats, Wistar; Solifenacin Succinate; Submandibular Gland; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder | 2004 |
Antimuscarinic agents exhibit local inhibitory effects on muscarinic receptors in bladder-afferent pathways.
Topics: Acetylcholine; Administration, Intravesical; Afferent Pathways; Animals; Atropine; Benzhydryl Compounds; Benzilates; Carbachol; Cresols; Dimethindene; Female; Infusions, Parenteral; Instillation, Drug; Mandelic Acids; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Nortropanes; Phenylpropanolamine; Pressure; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Tolterodine Tartrate; Urinary Bladder; Urodynamics | 2005 |
Altered neurogenic and mechanical responses to acetylcholine, ATP and substance P in detrusor from rat with outlet obstruction.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Atropine; Cholinergic Agonists; Cyclooxygenase Inhibitors; Electric Stimulation; Female; In Vitro Techniques; Indomethacin; Mandelic Acids; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Rats; Rats, Sprague-Dawley; Substance P; Suramin; Urethra; Urinary Bladder; Urinary Bladder Neck Obstruction | 2006 |
Pharmacological characterization of a new antimuscarinic agent, solifenacin succinate, in comparison with other antimuscarinic agents.
Topics: Animals; Atropine; Benzhydryl Compounds; Benzilates; Benzofurans; Binding, Competitive; Carbachol; CHO Cells; Cholinergic Agonists; Cresols; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mandelic Acids; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Muscarinic; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Transfection; Urinary Bladder; Urinary Bladder, Overactive; Urination | 2007 |
Ratiometric Ca+2 measurement in human recombinant muscarinic receptor subtypes using the Flexstation scanning fluorometer.
Topics: Animals; Atropine; Benzhydryl Compounds; Calcium; CHO Cells; Cresols; Cricetinae; Cricetulus; Fluorescence; Fluorescent Dyes; Fluorometry; Fura-2; Humans; Mandelic Acids; Muscarinic Antagonists; Phenylpropanolamine; Radioligand Assay; Receptor, Muscarinic M1; Receptor, Muscarinic M3; Receptor, Muscarinic M5; Scopolamine Derivatives; Tolterodine Tartrate; Transfection | 2009 |
Urothelial/lamina propria spontaneous activity and the role of M3 muscarinic receptors in mediating rate responses to stretch and carbachol.
Topics: Animals; Atropine; Benzhydryl Compounds; Benzofurans; Carbachol; Cresols; Diamines; Mandelic Acids; Mucous Membrane; Muscarinic Antagonists; Muscle Contraction; Phenylpropanolamine; Piperidines; Pirenzepine; Pyrrolidines; Quinuclidines; Receptor, Muscarinic M3; Solifenacin Succinate; Stress, Mechanical; Swine; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder; Urothelium | 2011 |
Minimum effective drug concentrations of a transdermal patch system containing procyclidine and physostigmine for prophylaxis against soman poisoning in rhesus monkeys.
Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Lethal Dose 50; Macaca mulatta; Male; Muscarinic Antagonists; Oximes; Physostigmine; Poisoning; Procyclidine; Pyridinium Compounds; Soman; Transdermal Patch | 2012 |