Page last updated: 2024-09-05

atropine and nociceptin

atropine has been researched along with nociceptin in 8 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(nociceptin)
Trials
(nociceptin)
Recent Studies (post-2010) (nociceptin)
26,7111,2591,6971,2956282

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)nociceptin (IC50)
Nociceptin receptorRattus norvegicus (Norway rat)0.0006
Nociceptin receptorHomo sapiens (human)0.001

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (50.00)18.2507
2000's3 (37.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K1
Hao, S; Ogawa, H1
Champion, HC; Kadowitz, PJ; Pierce, RL1
Kannan, H; Kato, K; Kunitake, T; Shirasaka, T; Takasaki, M1
Dun, NJ; Hwang, BH; Mizoguchi, H; Nagase, H; Narita, M; Oji, DE; Tseng, LF1
Calo, G; Guerrini, R; Pheng, LH; Regoli, D1
Horie, S; Ishihara, S; Minowa, S; Murayama, T; Tsuchiya, S; Watanabe, K1
Grandi, D; Guerrini, R; Lupo, D; Massi, M; Morini, G; Polidori, C1

Other Studies

8 other study(ies) available for atropine and nociceptin

ArticleYear
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
    Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21

    Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes, Liver; Neuralgia; Nociceptin Receptor; Pyrroles; Rats; Receptors, Opioid; Structure-Activity Relationship

2010
Naltrexone, but not atropine or yohimbine, antagonizes suppression of formalin-induced spinal sensitization by intrathecal nociceptin.
    Life sciences, 1998, Volume: 63, Issue:11

    Topics: Animals; Atropine; Depression, Chemical; Formaldehyde; Injections, Spinal; Injections, Subcutaneous; Male; Naltrexone; Narcotic Antagonists; Nociceptin; Nociceptors; Opioid Peptides; Pain Measurement; Parasympatholytics; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Spine; Sympatholytics; Yohimbine

1998
Nociceptin, a novel endogenous ligand for the ORL1 receptor, dilates isolated resistance arteries from the rat.
    Regulatory peptides, 1998, Nov-30, Volume: 78, Issue:1-3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Atropine; Calcitonin Gene-Related Peptide; Dynorphins; Enkephalin, Methionine; Mesentery; Muscle, Smooth, Vascular; Naloxone; Nitroarginine; Nociceptin; Nociceptin Receptor; Opioid Peptides; Phentolamine; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Vascular Resistance; Vasodilator Agents

1998
Nociceptin modulates renal sympathetic nerve activity through a central action in conscious rats.
    The American journal of physiology, 1999, Volume: 277, Issue:4

    Topics: Animals; Atropine; Blood Pressure; Brain; Denervation; Heart Rate; Kidney; Male; Naloxone; Narcotic Antagonists; Nociceptin; Opioid Peptides; Propranolol; Rats; Rats, Wistar; Sinus of Valsalva; Sympathetic Nervous System

1999
Identification of the G-protein-coupled ORL1 receptor in the mouse spinal cord by [35S]-GTPgammaS binding and immunohistochemistry.
    British journal of pharmacology, 1999, Volume: 128, Issue:6

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Atropine; Autoradiography; Baclofen; Binding, Competitive; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Haloperidol; Immunohistochemistry; In Vitro Techniques; Male; Membranes; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Nociceptin; Nociceptin Receptor; Opioid Peptides; Peptide Fragments; Propranolol; Receptors, Opioid; Somatostatin; Spinal Cord; Sulfur Radioisotopes; Yohimbine

1999
[Nphe(1)]nociceptin-(1-13)NH(2) selectively antagonizes nociceptin effects in the rabbit isolated ileum.
    European journal of pharmacology, 2000, Jun-02, Volume: 397, Issue:2-3

    Topics: Animals; Atropine; Diamines; Dose-Response Relationship, Drug; Dynorphins; Female; Humans; Ileum; In Vitro Techniques; Male; Muscle Relaxation; Naloxone; Naphthalenes; Narcotic Antagonists; Neuropeptide Y; Nociceptin; Nociceptin Receptor; Opioid Peptides; Pancreatic Polypeptide; Peptide Fragments; Rabbits; Receptors, Opioid; Tetrodotoxin

2000
Gastric acid secretion stimulated by centrally injected nociceptin in urethane-anesthetized rats.
    European journal of pharmacology, 2002, Apr-19, Volume: 441, Issue:1-2

    Topics: Anesthesia; Anesthetics, Intravenous; Animals; Atropine; Deoxyglucose; Dose-Response Relationship, Drug; Gastric Acid; Gastric Mucosa; Injections, Intraventricular; Injections, Subcutaneous; Male; Naloxone; Nociceptin; Nociceptin Receptor; Opioid Peptides; Peptide Fragments; Rats; Rats, Wistar; Receptors, Opioid; Stomach; Time Factors; Urethane; Vasodilator Agents

2002
Peripheral mechanisms involved in gastric mucosal protection by intracerebroventricular and intraperitoneal nociceptin in rats.
    Endocrinology, 2005, Volume: 146, Issue:9

    Topics: Animals; Anti-Arrhythmia Agents; Atropine; Bretylium Compounds; Calcitonin Gene-Related Peptide; Central Nervous System Depressants; Ethanol; Ganglionic Blockers; Gastric Mucosa; Hexamethonium; Injections, Intraperitoneal; Injections, Intraventricular; Male; Miotics; Neurons, Afferent; Nitric Oxide; Nociceptin; Opioid Peptides; Parasympathetic Nervous System; Parasympatholytics; Peptide Fragments; Rats; Rats, Wistar; Sympathetic Nervous System; Vagotomy

2005