Page last updated: 2024-09-05

atropine and nalbuphine

atropine has been researched along with nalbuphine in 6 studies

Compound Research Comparison

Studies (atropine)	Trials (atropine)	Recent Studies (post-2010) (atropine)	Studies (nalbuphine)	Trials (nalbuphine)	Recent Studies (post-2010) (nalbuphine)
26,711	1,259	1,697	793	269	185

Protein Interaction Comparison

Protein	Taxonomy	nalbuphine (IC50)
Mu-type opioid receptor	Homo sapiens (human)	0.0578
Delta-type opioid receptor	Homo sapiens (human)	1.1195
Kappa-type opioid receptor	Homo sapiens (human)	0.097

Research

Studies (6)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (16.67)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (66.67)	29.6817
2010's	1 (16.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Hanig, JP; Hui, FW; Sun, CJ; Tocus, EC	1
Bakhshandeh, M; Bjorksten, AR; Doufas, AG; Greif, R; Laciny, S; Larson, MD; Mokhtarani, M; Rajek, AM; Sessler, DI	1

Reviews

1 review(s) available for atropine and nalbuphine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for atropine and nalbuphine

Article	Year
Neither nalbuphine nor atropine possess special antishivering activity. Anesthesia and analgesia, 2001, Volume: 93, Issue:3 Topics: Adult; Analgesics, Opioid; Atropine; Body Temperature; Cold Temperature; Conscious Sedation; Dose-Response Relationship, Drug; Heart Rate; Humans; Injections, Intravenous; Male; Muscarinic Antagonists; Nalbuphine; Oxygen Consumption; Oxyhemoglobins; Pupil; Respiratory Mechanics; Shivering; Vomiting	2001

Article

Year

Neither nalbuphine nor atropine possess special antishivering activity.

Anesthesia and analgesia, 2001, Volume: 93, Issue:3

Topics: Adult; Analgesics, Opioid; Atropine; Body Temperature; Cold Temperature; Conscious Sedation; Dose-Response Relationship, Drug; Heart Rate; Humans; Injections, Intravenous; Male; Muscarinic Antagonists; Nalbuphine; Oxygen Consumption; Oxyhemoglobins; Pupil; Respiratory Mechanics; Shivering; Vomiting

2001

Other Studies

4 other study(ies) available for atropine and nalbuphine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
The effect of tripelennamine alone and in combination with opiates to produce antinociception in mice. Life sciences, 1983, Apr-04, Volume: 32, Issue:14 Topics: Analgesia; Animals; Atropine; Dose-Response Relationship, Drug; Drug Interactions; Histamine; Male; Mice; Morphine; Nalbuphine; Naloxone; Narcotics; Tripelennamine	1983