Page last updated: 2024-09-05

atropine and nalbuphine

atropine has been researched along with nalbuphine in 6 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(nalbuphine)
Trials
(nalbuphine)
Recent Studies (post-2010) (nalbuphine)
26,7111,2591,697793269185

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)nalbuphine (IC50)
Mu-type opioid receptorHomo sapiens (human)0.0578
Delta-type opioid receptorHomo sapiens (human)1.1195
Kappa-type opioid receptorHomo sapiens (human)0.097

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's0 (0.00)18.2507
2000's4 (66.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Hanig, JP; Hui, FW; Sun, CJ; Tocus, EC1
Bakhshandeh, M; Bjorksten, AR; Doufas, AG; Greif, R; Laciny, S; Larson, MD; Mokhtarani, M; Rajek, AM; Sessler, DI1

Reviews

1 review(s) available for atropine and nalbuphine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for atropine and nalbuphine

ArticleYear
Neither nalbuphine nor atropine possess special antishivering activity.
    Anesthesia and analgesia, 2001, Volume: 93, Issue:3

    Topics: Adult; Analgesics, Opioid; Atropine; Body Temperature; Cold Temperature; Conscious Sedation; Dose-Response Relationship, Drug; Heart Rate; Humans; Injections, Intravenous; Male; Muscarinic Antagonists; Nalbuphine; Oxygen Consumption; Oxyhemoglobins; Pupil; Respiratory Mechanics; Shivering; Vomiting

2001

Other Studies

4 other study(ies) available for atropine and nalbuphine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
The effect of tripelennamine alone and in combination with opiates to produce antinociception in mice.
    Life sciences, 1983, Apr-04, Volume: 32, Issue:14

    Topics: Analgesia; Animals; Atropine; Dose-Response Relationship, Drug; Drug Interactions; Histamine; Male; Mice; Morphine; Nalbuphine; Naloxone; Narcotics; Tripelennamine

1983