Page last updated: 2024-09-05

atropine and montelukast

atropine has been researched along with montelukast in 9 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(montelukast)
Trials
(montelukast)
Recent Studies (post-2010) (montelukast)
26,7111,2591,6971,965598777

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)montelukast (IC50)
Epidermal growth factor receptorHomo sapiens (human)3.197
Tyrosine-protein kinase FynHomo sapiens (human)4.702
Beta-2 adrenergic receptorHomo sapiens (human)3.488
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)2.689
Alpha-2A adrenergic receptorHomo sapiens (human)3.919
Adenosine receptor A3Homo sapiens (human)0.434
Cytochrome P450 2C8Homo sapiens (human)0.7
Muscarinic acetylcholine receptor M1Homo sapiens (human)8.045
Beta-3 adrenergic receptorHomo sapiens (human)4.3
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.434
Alpha-2C adrenergic receptorHomo sapiens (human)5.279
Muscarinic acetylcholine receptor M3Homo sapiens (human)6.626
Substance-K receptorHomo sapiens (human)3.822
Sodium-dependent noradrenaline transporter Homo sapiens (human)2.689
Thromboxane-A synthase Homo sapiens (human)1.525
D(3) dopamine receptorHomo sapiens (human)7.747
Delta-type opioid receptorHomo sapiens (human)4.795
5-hydroxytryptamine receptor 2BHomo sapiens (human)6.256
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.434
Sodium-dependent dopamine transporter Homo sapiens (human)2.601
Mitogen-activated protein kinase 14Homo sapiens (human)0.856
Leukotriene C4 synthaseHomo sapiens (human)5
Cysteinyl leukotriene receptor 1Homo sapiens (human)0.0015

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (44.44)29.6817
2010's5 (55.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Hiyama, Y; Ishimura, M; Kataoka, S; Maeda, T; Suda, M1
Chang, BS; Chang, JC; Huang, SC; Wang, YS1

Reviews

1 review(s) available for atropine and montelukast

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

8 other study(ies) available for atropine and montelukast

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Effects of KP-496, a novel dual antagonist for leukotriene D4 and thromboxane A2 receptors, on contractions induced by various agonists in the guinea pig trachea.
    Allergology international : official journal of the Japanese Society of Allergology, 2006, Volume: 55, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetates; Acetylcholine; Albuterol; Animals; Atropine; Benzoquinones; Carbachol; Chromones; Cyclopropanes; Dinoprost; Drug Evaluation, Preclinical; Guinea Pigs; Heptanoic Acids; Histamine; In Vitro Techniques; Indoles; Indomethacin; Ketanserin; Ketotifen; Leukotriene Antagonists; Leukotriene D4; Male; Muscle Contraction; Muscle, Smooth; Phenylcarbamates; Powders; Procaterol; Prostaglandin Antagonists; Prostaglandin D2; Quinolines; Receptors, Thromboxane A2, Prostaglandin H2; Serotonin; Substance P; Sulfides; Sulfonamides; Tosyl Compounds; Trachea; Tryptophan

2006
Cysteinyl leucotriene receptor type 1 mediates contraction in human and guinea-pig oesophagus.
    Neurogastroenterology and motility, 2008, Volume: 20, Issue:10

    Topics: Acetates; Animals; Atropine; Capsaicin; Carbachol; Cholinergic Agonists; Cyclopropanes; Esophagus; Guinea Pigs; Humans; Indoles; Leukotriene Antagonists; Leukotrienes; Male; Muscarinic Antagonists; Muscle Contraction; Phenylcarbamates; Quinolines; Receptors, Leukotriene; Sensory System Agents; Sodium Channel Blockers; SRS-A; Sulfides; Sulfonamides; Tetrodotoxin; Tosyl Compounds

2008