atropine has been researched along with metyrapone in 7 studies
| Studies (atropine) | Trials (atropine) | Recent Studies (post-2010) (atropine) | Studies (metyrapone) | Trials (metyrapone) | Recent Studies (post-2010) (metyrapone) |
|---|---|---|---|---|---|
| 26,711 | 1,259 | 1,697 | 3,415 | 128 | 250 |
| Protein | Taxonomy | atropine (IC50) | metyrapone (IC50) |
|---|---|---|---|
| Cytochrome P450 1A2 | Homo sapiens (human) | 4.8 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 2.8659 | |
| Cytochrome P450 2C8 | Homo sapiens (human) | 5 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 4.6 | |
| Cytochrome P450 11B1, mitochondrial | Bos taurus (cattle) | 7.83 | |
| Cytochrome P450 11B1, mitochondrial | Rattus norvegicus (Norway rat) | 4.7357 | |
| Cytochrome P450 11B1, mitochondrial | Homo sapiens (human) | 0.0181 | |
| Cytochrome P450 11B2, mitochondrial | Homo sapiens (human) | 0.0838 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 5 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Agrawal, U; Srivastava, AK | 1 |
| Ishizuka, T; Kijima, H; Koike, T; Kubo, M; Shimizu, C; Takano, A; Takano, K; Yamane, Y | 1 |
1 review(s) available for atropine and metyrapone
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
6 other study(ies) available for atropine and metyrapone
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Involvement of pituitary-interrenal axis and cholinergic mechanisms during the cold-shock leucocyte sequence in a fresh water tropical teleost, Colisa fasciatus.
Topics: Acetylcholine; Animals; Atropine; Cold Temperature; Fishes; Hydrocortisone; Leukocytes; Metyrapone; Pituitary-Adrenal System; Stress, Physiological | 1977 |
Involvement of the cholinergic pathway in the pathogenesis of pituitary Cushing's syndrome.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adrenocorticotropic Hormone; Atropine; Choline; Cushing Syndrome; Dexamethasone; Female; Humans; Hydrocortisone; Metyrapone; Middle Aged; Muscarinic Antagonists; Petrosal Sinus Sampling; Pirenzepine; Pituitary Neoplasms | 2001 |