atropine has been researched along with metoclopramide in 105 studies
Studies (atropine) | Trials (atropine) | Recent Studies (post-2010) (atropine) | Studies (metoclopramide) | Trials (metoclopramide) | Recent Studies (post-2010) (metoclopramide) |
---|---|---|---|---|---|
26,711 | 1,259 | 1,697 | 5,044 | 1,216 | 623 |
Protein | Taxonomy | atropine (IC50) | metoclopramide (IC50) |
---|---|---|---|
5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 2.383 | |
Myeloperoxidase | Homo sapiens (human) | 0.35 | |
Alpha-2A adrenergic receptor | Homo sapiens (human) | 2.721 | |
Cytochrome P450 2D6 | Homo sapiens (human) | 0.8 | |
D(2) dopamine receptor | Homo sapiens (human) | 0.127 | |
Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 7.8 | |
5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 7.8 | |
Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 7.7 | |
Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 7.7 | |
Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 7.7 | |
Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 7.8 | |
5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 3.675 | |
5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 2.383 | |
5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 7.8 | |
5-hydroxytryptamine receptor 1D | Rattus norvegicus (Norway rat) | 7.8 | |
5-hydroxytryptamine receptor 1F | Rattus norvegicus (Norway rat) | 7.8 | |
D(3) dopamine receptor | Homo sapiens (human) | 0.2 | |
5-hydroxytryptamine receptor 3A | Rattus norvegicus (Norway rat) | 0.88 | |
5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.63 | |
Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 7.8 | |
D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.6237 | |
5-hydroxytryptamine receptor 3B | Rattus norvegicus (Norway rat) | 0.88 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 59 (56.19) | 18.7374 |
1990's | 19 (18.10) | 18.2507 |
2000's | 17 (16.19) | 29.6817 |
2010's | 10 (9.52) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Topliss, JG; Yoshida, F | 1 |
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
Ahman, M; Holmén, AG; Wan, H | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Bellman, K; Knegtel, RM; Settimo, L | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Bury, RW; Mashford, ML | 1 |
Geller, LI; Petrenko, VF | 1 |
Arnon, N; Cohen, H; LeRoith, D; Spitz, IM; Trestian, S | 1 |
Gibbons, DO; Lant, AF | 1 |
Peitersen, E; Vesterhauge, S | 1 |
Jersky, J; Leroith, D; Spitz, IM; Zylber, E | 1 |
Laitinen, S; Larmi, TK; Mokka, RE; Valanne, JV | 1 |
Männistö, P | 1 |
Brock-Utne, JG; Downing, JW | 1 |
Fuchs, HF; Maeder, HU | 1 |
Deshpande, S; Fry, EN | 1 |
Moshal, MG; Pillary, K; Rawat, R; Spitaels, JM | 1 |
Brock-Utne, JG; Dimopoulos, GE; Downing, JW; Moshal, MG; Naicker, M; Rubin, J | 1 |
Dundee, JW; Gamble, JA; Gaston, JH; Nair, SG | 1 |
Zastrow, R | 1 |
Eggers, C | 1 |
Kojima, T; Koyama, Y; Marumo, H; Nakamura, N; Shiozaki, S | 1 |
Fry, EN | 1 |
Kolodej, A; Kowalewski, K | 1 |
Csendes, A; Defilippi, C; Valenzuela, JE | 1 |
Breiter, N; Sassy, T; Trott, KR | 1 |
Fileccia, R; La Rocca, G; Mule, F; Urso, SA | 1 |
Glyngdal, P; Jensen, A; Müller, TF; Naesh, O; Svare, E | 1 |
Davenport, DJ; Kenny, JE; Leib, MS; Matz, ME; Monroe, WE; Nelson, LP | 1 |
Bianconi, L; Buonanno, G; Caiazza, A; Capretti, L; Cavazzini, U; Chiodera, P; Coiro, V; Marcato, A; Speroni, G; Volpi, R | 1 |
Bateman, DN; Brunetto, AL; Gibson, R; Laker, MF; Pearson, AD; Rashid, MU | 1 |
Adner, N | 1 |
Bevilacqua, M; Iovino, M; Monteleone, P; Norbiato, G; Steardo, L | 1 |
Meyer, EC; Sommers, DK; van Wyk, M | 1 |
Meyer, EC; Moncrieff, J; Sommers, DK; van Wyk, M | 1 |
Eggena, P; Plasko, R; Pullen, W; Stern, N; Tuck, ML | 1 |
Bianconi, L; Caiazza, A; Capretti, L; Chiodera, P; Coiro, V; Fagnoni, F; Schianchi, L; Speroni, G; Volpi, R | 1 |
Ivanova, VS; Modestova, EV; Rotenberg, GB; Tsimmerman, IaS | 1 |
Sanger, GJ | 1 |
Merritt, AM; Ruckebusch, Y | 1 |
Dieguez, C; Gomez-Pan, A; Hall, R; Jordan, V; Lafaffian, I; Rodriguez-Arnao, MD; Scanlon, MF | 1 |
Neugebauer, A; Terhaag, B | 1 |
Griffin, P; Marshall, RW; McKirdy, HC | 1 |
Laurén, L; Scheinin, M; Syvälahti, EK; Tarvonen, S; Ylitalo, A | 1 |
Kinni, ME; Stout, MM | 1 |
Syvälahti, EK; Ylitalo, A | 1 |
Buyniski, JP; Gidda, JS | 1 |
Funaki, T; Furuta, S; Kaneniwa, N | 1 |
McClelland, GR; Sutton, JA | 1 |
Janssen, PA; Reyntjens, AJ; Schuurkes, JA; Van Daele, PG; Van Nueten, JM | 1 |
Edwards, RM | 1 |
Harrold, D; Strombeck, DR | 1 |
Funaki, T; Furuta, S; Kaneniwa, N; Watari, N | 1 |
Thommesen, P | 1 |
Fontaine, J; Reuse, JJ | 1 |
Clarke, RS; Dundee, JW | 1 |
Guelrud, M | 1 |
Hansen, W | 1 |
Iizuka, M; Takaiti, O; Yamada, K | 1 |
Helmreich, I; Hertting, G; Reimann, W; Starke, K | 1 |
Costall, B; Gunning, SJ; Naylor, RJ; Simpson, KH | 1 |
Burrows, CF | 1 |
Berman, DJ; Firlit, CF | 1 |
Hey, VM; Phillips, K; Woods, I | 1 |
Birkett, DJ; Grygiel, JJ; Meffin, PJ; Smith, KJ; Wing, LM | 1 |
Brock-Utne, JG; Dimopoulos, GE; Downing, JW; Moshal, MG | 1 |
de Villiers, F | 1 |
Tikholov, K | 1 |
Cotton, BR; Smith, G | 1 |
Brodde, OE; Freistühler, J; Meyer, FJ; Schemuth, W | 1 |
Behar, J; Fox, S | 1 |
Alander, T; Andén, NE; Grabowska-Andén, M | 1 |
Lux, G; Rösch, W | 1 |
Gregory, PC; McFadyen, M; Rayner, DV | 1 |
Buchheit, KH; Buhl, T | 1 |
Pilot, MA; Qin, XY; Scott, M; Thompson, H | 1 |
Haga, K; Odani, N; Setoguchi, M | 1 |
Gin, T | 1 |
Brooks, DC; Freiberger, D; Gosnell, JL; Steinbrook, RA | 1 |
Andrews, FM; Doherty, TJ; Frazier, DL; Provenza, MK | 1 |
Bruyneel, P; Cornil, P; De Smet, MC; Schrijvers, D; Tai-Apin, C; Vermorken, JB | 1 |
Hung, CR | 1 |
Suga, A; Tanaka, M; Toyooka, H | 1 |
Chen, D; Huang, L; Ning, Z; Wu, CF | 1 |
Belogorodtseva, RI; Fedorov, NE; Mishchuk, IF; Nemtsov, LM; Shchuko, AG | 1 |
Hasegawa, Y; Kangawa, K; Kojima, M; Kurose, Y; Sugino, T; Terashima, Y; Yamagishi, M; Yamaura, J | 1 |
CASTERA, R; CORNET, A; ECOIFFIER, J; GRIVAUX, M; GUERRE, J; JUSTIN-BESANCON, L; WATTEZ, E | 1 |
Kim, HY; Kwon, OK; Nam, TC | 1 |
Arnold, S; Binder, H; Burger, DM; Hubler, M; Keiser, M; Wiestner, T | 1 |
Endo, M; Hanawa, T; Hoshino, T; Oikawa, T | 1 |
Ehsani-Kheradgerdi, A; Grünberg, W; Mohri, M; Sharifi, K | 1 |
Gerszten, RE; Jin, S; Jin, YN; Kokel, D; Liu, Y; Macrae, CA; Peterson, RT; Roberts, LD; Sarkar, KS; Van Ham, TJ | 1 |
Choi, SC; Jeon, WC; Jung, YS; Kim, GW; Lee, JS; Min, YG; Park, EJ | 1 |
4 review(s) available for atropine and metoclopramide
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Pharmacology of the ruminant gastroduodenal junction.
Topics: 5-Hydroxytryptophan; Animals; Antidiarrheals; Atropine; Bethanechol; Bethanechol Compounds; Dogs; Duodenum; Gastric Emptying; Gastrointestinal Motility; Hydrogen-Ion Concentration; Metoclopramide; Morphine; Serotonin; Sheep; Somatostatin; Stomach; Vasoactive Intestinal Peptide | 1985 |
Aspiration pneumonitis: predisposing conditions and prevention.
Topics: Atropine; Cimetidine; Citrates; Citric Acid; Duodenal Ulcer; Esophagogastric Junction; Gastric Acid; Gastroesophageal Reflux; Gastrointestinal Contents; Humans; Hydrogen-Ion Concentration; Larynx; Metoclopramide; Pneumonia, Aspiration; Pressure; Ranitidine; Stress, Psychological | 1986 |
[Dietary and drug therapy of intestinal disease].
Topics: Aerophagy; Anti-Inflammatory Agents; Atropine; beta-Galactosidase; Cathartics; Colitis, Ulcerative; Colonic Diseases, Functional; Constipation; Crohn Disease; Diarrhea; Dietary Fiber; Flatulence; Food, Formulated; Gastrointestinal Motility; Glutens; Humans; Intestinal Diseases; Malabsorption Syndromes; Metoclopramide; Parenteral Nutrition; Substance-Related Disorders; Sulfasalazine; Water-Electrolyte Imbalance | 1980 |
15 trial(s) available for atropine and metoclopramide
Article | Year |
---|---|
[Evaluation of the action of drug agents on the tonus of the lower esophageal sphincter].
Topics: Atropine; Bicarbonates; Chronic Disease; Clinical Trials as Topic; Drug Evaluation; Duodenal Diseases; Enteritis; Esophagus; Humans; Hydrogen-Ion Concentration; Metoclopramide; Muscle Relaxants, Central; Muscle Tonus; Papaverine; Peptic Ulcer | 1978 |
Oral premedication: diazepam, metoclopramide and a drink.
Topics: Administration, Oral; Adult; Atropine; Diazepam; Drinking; Female; Humans; Injections, Intramuscular; Male; Meperidine; Metoclopramide; Preanesthetic Medication; Time Factors; Vomiting | 1977 |
Effect of atropine and metoclopramide on serum gastrin response to protein in patients with duodenal ulcers.
Topics: Adult; Atropine; Depression, Chemical; Dietary Proteins; Duodenal Ulcer; Gastrins; Humans; Metoclopramide | 1977 |
The administration of metoclopramide with atropine. A drug interaction effect on the gastro-oesophageal sphincter in man.
Topics: Adolescent; Adult; Atropine; Drug Interactions; Esophagogastric Junction; Humans; Injections, Intravenous; Metoclopramide; Middle Aged; Pressure | 1976 |
Metoclopramide (Primperan) in the treatment of ureterolithiasis. A prospective double-blind study of metoclopramide compared with morphatropin on ureteral colic.
Topics: Acute Disease; Atropine; Double-Blind Method; Drug Combinations; Drug Evaluation; Humans; Metoclopramide; Morphine; Palliative Care; Prospective Studies; Ureteral Calculi | 1990 |
5-HT1-, but not 5-HT2-serotonergic, M1-, M2-muscarinic cholinergic or dopaminergic receptors mediate the ACTH/cortisol response to metoclopramide in man.
Topics: Adrenocorticotropic Hormone; Adult; Atropine; Bromocriptine; Dose-Response Relationship, Drug; Humans; Hydrocortisone; Ketanserin; Male; Metergoline; Metoclopramide; Pirenzepine; Receptors, Adrenergic; Receptors, Cholinergic; Receptors, Dopamine; Receptors, Muscarinic; Receptors, Serotonin | 1990 |
The effect of pharmacological modification of gastric emptying and mouth-to-caecum transit time on the absorption of sugar probe marker molecules of intestinal permeability in normal man.
Topics: Adult; Atropine; Carbohydrates; Gastric Emptying; Gastrointestinal Transit; Humans; Intestinal Absorption; Male; Metoclopramide; Permeability | 1990 |
Influence of dopaminergic, adrenergic and cholinergic blockade and TRH administration on GH responses to GRF 1-29.
Topics: Adult; Atropine; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Male; Metoclopramide; Moxisylyte; Neurotransmitter Agents; Peptide Fragments; Pituitary Gland; Prolactin; Sermorelin; Thyrotropin-Releasing Hormone | 1986 |
Differences in cardiac but not in neuroendocrine responses in healthy volunteers after administration of two antimuscarinic agents, atropine and pirenzepine.
Topics: Adult; Atropine; Benzodiazepinones; Female; Growth Hormone; Heart; Heart Rate; Humans; Male; Metoclopramide; Pirenzepine; Prolactin; Reference Values; Time Factors | 1986 |
The effect of metoclopramide and atropine on the absorption of orally administered mexiletine.
Topics: Administration, Oral; Adolescent; Adult; Atropine; Biological Availability; Clinical Trials as Topic; Drug Therapy, Combination; Gastric Emptying; Half-Life; Humans; Male; Metoclopramide; Mexiletine; Propylamines | 1980 |
Effect of metoclopramide given before atropine sulphate on lower oesophageal sphincter tone.
Topics: Adult; Atropine; Drug Interactions; Esophagogastric Junction; Humans; Metoclopramide | 1982 |
Single and combined effects of atropine and metoclopramide on the lower oesophageal sphincter pressure.
Topics: Adult; Atropine; Drug Interactions; Esophagogastric Junction; Female; Humans; Male; Metoclopramide; Pressure; Stomach; Time Factors | 1981 |
Prophylactic antiemetics for laparoscopic cholecystectomy: ondansetron versus droperidol plus metoclopramide.
Topics: Adrenergic Agonists; Adult; Antiemetics; Atropine; Chemoprevention; Cholecystectomy, Laparoscopic; Cross-Over Studies; Droperidol; Drug Combinations; Ephedrine; Female; Humans; Injections, Intravenous; Intraoperative Care; Length of Stay; Male; Metoclopramide; Muscarinic Antagonists; Nausea; Ondansetron; Patient Admission; Patient Discharge; Postoperative Complications; Prospective Studies; Vomiting | 1996 |
Effects of i.v. metoclopramide, atropine and their combination on gastric insufflation in children anaesthetized with sevoflurane and nitrous oxide.
Topics: Anesthesia, General; Anesthetics, Inhalation; Antiemetics; Atropine; Child; Double-Blind Method; Drug Therapy, Combination; Esophagogastric Junction; Humans; Infant; Infusions, Intravenous; Insufflation; Methyl Ethers; Metoclopramide; Nitrous Oxide; Pressure; Respiratory System; Sevoflurane; Stomach; Vomiting | 2001 |
Adjunctive atropine versus metoclopramide: can we reduce ketamine-associated vomiting in young children? a prospective, randomized, open, controlled study.
Topics: Anesthetics, Dissociative; Antiemetics; Atropine; Child, Preschool; Female; Humans; Infant; Ketamine; Male; Metoclopramide; Prospective Studies; Treatment Outcome; Vomiting | 2012 |
86 other study(ies) available for atropine and metoclopramide
Article | Year |
---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
The effects of metoclopramide in modifying the response of isolated guinea-pig ileum to various agonists.
Topics: Acetylcholine; Animals; Atropine; Barium; Female; Guanethidine; Guinea Pigs; Histamine; Hydrogen-Ion Concentration; Ileum; In Vitro Techniques; Male; Metoclopramide; Muscle Contraction; Muscle, Smooth; Pimozide; Substance P; Tetrodotoxin | 1976 |
Failure of metoclopramide to influence LH, FSH and TSH secretion or their responses to releasing hormones.
Topics: Adolescent; Adult; Atropine; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Gonadotropins, Pituitary; Humans; Levodopa; Luteinizing Hormone; Male; Metoclopramide; Pituitary Hormone-Releasing Hormones; Prolactin; Thyrotropin; Thyrotropin-Releasing Hormone | 1979 |
Effects of intravenous and oral propantheline and metoclopramide on ethanol absorption.
Topics: Administration, Oral; Adult; Atropine; Biological Availability; Chromatography, Gas; Chromatography, Thin Layer; Ethanol; Humans; Hydrogen-Ion Concentration; Hydrolysis; Injections, Intravenous; Intestinal Absorption; Male; Metoclopramide; Propantheline; Time Factors | 1975 |
The effects of some drugs on the caloric induced nystagmus.
Topics: Amphetamine; Atropine; Caffeine; Caloric Tests; Cyclizine; Eye Movements; Humans; Metoclopramide; Promethazine; Scopolamine; Thiethylperazine; Vestibule, Labyrinth | 1979 |
Atropine suppression of basal and metoclopramide-induced human pancreatic polypeptide secretion in man.
Topics: Adult; Aged; Atropine; Drug Therapy, Combination; Female; Humans; Male; Metoclopramide; Middle Aged; Pancreatic Polypeptide; Sex Factors; Time Factors | 1979 |
Anaesthesia induction and lower oesophageal sphincter pressure.
Topics: Anesthesia, General; Anesthetics; Animals; Atropine; Dogs; Drug Evaluation, Preclinical; Drug Interactions; Esophagogastric Junction; Female; Gastroesophageal Reflux; Male; Metoclopramide; Preanesthetic Medication; Pressure; Succinylcholine; Thiopental | 1978 |
The effect of crystal size, gastric content and emptying rate on the absorption of nitrofurantoin in healthy human volunteers.
Topics: Adult; Antacids; Atropine; Female; Food; Gastric Emptying; Gastrointestinal Motility; Humans; Intestinal Absorption; Male; Metoclopramide; Nitrofurantoin; Particle Size; Time Factors | 1978 |
Anaesthesia for caesarean section.
Topics: Anesthesia, Intravenous; Anesthesia, Obstetrical; Atropine; Cesarean Section; Female; Humans; Metoclopramide; Pregnancy | 1978 |
[Pharmacoradiography of the gastro intestinal tract (author's transl)].
Topics: Atropine; Butylscopolammonium Bromide; Gastrointestinal Diseases; Gastrointestinal Motility; Glucagon; Humans; Metoclopramide; Morphine; Oxyphenonium; Parasympatholytics; Physostigmine; Propantheline; Radiography | 1976 |
Some pharmacological factors influencing the absorption of diazepam following oral administration.
Topics: Administration, Oral; Adult; Atropine; Diazepam; Female; Humans; Intestinal Absorption; Metoclopramide; Middle Aged; Narcotics; Preanesthetic Medication; Time Factors | 1976 |
[Acute pancreatitis--pancreas necrosis].
Topics: Acute Disease; Aprotinin; Atropine; Drainage; Fasting; Humans; Intestinal Obstruction; Metoclopramide; Pancreatitis; Plasma Substitutes; Shock | 1975 |
[Non-delirious toxic psychoses in children (author's transl)].
Topics: Affective Symptoms; Atropine; Benzydamine; Cannabis; Child; Child, Preschool; Delusions; Female; Fenfluramine; Hallucinations; Hallucinogens; Humans; Infant; Limbic System; Male; Metoclopramide; Psychoses, Substance-Induced; Pyrazoles; Visual Cortex | 1975 |
Pharmacological studies of caerulein. II. The possibility of mediation through the central nervous system.
Topics: Animals; Apomorphine; Atropine; Blood Pressure; Central Nervous System; Ceruletide; Chlorpromazine; Copper; Dogs; Female; Gallbladder; Gastrointestinal Motility; Male; Metoclopramide; Splanchnic Nerves; Sulfates; Vagotomy; Vomiting | 1975 |
Letter: Metoclopramide and oral premedication.
Topics: Administration, Oral; Atropine; Diazepam; Metoclopramide; Preanesthetic Medication | 1975 |
Effect of metoclopramide on myoelectrical and mechanical activity of the isolated canine stomach perfused extracorporeally.
Topics: Animals; Atropine; Dogs; Drug Interactions; Gastrointestinal Motility; Glucagon; Hexamethonium Compounds; Methacholine Compounds; Metoclopramide; Pentagastrin; Perfusion; Stomach; Tetrodotoxin; Vagus Nerve; Vascular Resistance | 1975 |
Manometric studies on the human pyloric sphincter. Effect of cigarette smoking, metoclopramide, and atropine.
Topics: Adult; Atropine; Gastrointestinal Motility; Humans; Hydrochloric Acid; Intubation, Gastrointestinal; Manometry; Metoclopramide; Middle Aged; Pressure; Pylorus; Smoking; Stomach Ulcer | 1976 |
[Acute and chronic disorders in gastric emptying after the x-ray irradiation of the rat stomach and their therapeutic modification].
Topics: Animals; Atropine; Carbachol; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Gastric Emptying; Metoclopramide; Radiation Injuries, Experimental; Rats; Rats, Inbred Strains; Stomach Diseases; Time Factors | 1992 |
Neurally mediated effects of metoclopramide on pigeon oesophageal muscle.
Topics: Animals; Atropine; Columbidae; Dose-Response Relationship, Drug; Electromyography; Esophagus; Guanethidine; Metoclopramide; Muscle, Smooth; Naloxone; Neural Pathways; Neuromuscular Junction; Serotonin; Tetrodotoxin; Time Factors | 1992 |
Evaluation of atropine, glucagon, and metoclopramide for facilitation of endoscopic intubation of the duodenum in dogs.
Topics: Animals; Atropine; Dogs; Duodenoscopy; Female; Gastrointestinal Motility; Glucagon; Intubation, Gastrointestinal; Male; Metoclopramide; Random Allocation | 1991 |
Influence of naloxone, atropine, and metoclopramide on ethanol augmentation of insulin secretion after intravenous glucose stimulation.
Topics: Adult; Atropine; Blood Glucose; C-Peptide; Dopamine; Dopamine Antagonists; Endorphins; Ethanol; Female; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Kinetics; Liver; Male; Metoclopramide; Muscarine; Naloxone | 1990 |
Evidence that cholinergic receptors of muscarinic type may modulate vasopressin release induced by metoclopramide.
Topics: Animals; Atropine; Drug Interactions; Male; Metoclopramide; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Secretory Rate; Vasopressins; Water | 1990 |
The effect of neostigmine on metoclopramide-induced aldosterone secretion after the administration of muscarinic antagonists in man.
Topics: Adult; Aldosterone; Atropine; Humans; Male; Metoclopramide; Muscarinic Antagonists; Neostigmine; Pirenzepine | 1990 |
The mean cumulative fraction absorbed-time profiles of paracetamol as an index of gastric emptying.
Topics: Acetaminophen; Adult; Atropine; Biological Availability; Gastric Emptying; Humans; Intestinal Absorption; Male; Metoclopramide; Neostigmine; Pirenzepine | 1990 |
Evidence for cholinergic modulation of aldosterone secretion in man.
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Atropine; Bethanechol; Bethanechol Compounds; Humans; Male; Metoclopramide; Middle Aged; Parasympatholytics; Receptors, Muscarinic | 1989 |
Muscarinic cholinergic, but not serotoninergic mediation of arginine vasopressin response to metoclopramide in man.
Topics: Adult; Arginine Vasopressin; Atropine; Dose-Response Relationship, Drug; Humans; Ketanserin; Kinetics; Male; Metergoline; Metoclopramide; Pirenzepine; Receptors, Muscarinic; Receptors, Serotonin | 1989 |
[Gastric evacuatory function in peptic ulcer studied using radionuclide research data].
Topics: Adolescent; Adult; Atropine; Female; Gastric Emptying; Gastrointestinal Transit; Humans; Iodine Radioisotopes; Male; Metoclopramide; Middle Aged; Peptic Ulcer; Radionuclide Imaging; Recurrence; Time Factors; Triolein | 1989 |
Effects of metoclopramide and domperidone on cholinergically mediated contractions of human isolated stomach muscle.
Topics: Acetylcholine; Atropine; Carbachol; Domperidone; Electric Stimulation; Humans; In Vitro Techniques; Metoclopramide; Muscle Contraction; Muscle, Smooth; Parasympathetic Nervous System; Stomach | 1985 |
[Modification of orocecal transit time of salazosulfapyridine by atropine and metoclopramide in healthy probands].
Topics: Adult; Atropine; Gastrointestinal Motility; Humans; Intestinal Absorption; Kinetics; Male; Metoclopramide; Sulfasalazine | 1986 |
Effect of drugs, hormones and electrical field stimulation on isolated muscle strips from human choledochoduodenal junction.
Topics: Acetylcholine; Ampulla of Vater; Atropine; Bile Ducts; Duodenum; Electric Stimulation; Gastrointestinal Hormones; Hormones; Humans; In Vitro Techniques; Metoclopramide; Morphine; Muscle Contraction; Neurotransmitter Agents; Opium; Sphincter of Oddi | 1987 |
Comparison of the effects of metoclopramide on sympathetic and muscarinic responses after pretreatment with atropine and pirenzepine.
Topics: Adult; Atropine; Blood Pressure; Catecholamines; Female; Heart Rate; Hemodynamics; Humans; Male; Metoclopramide; Pirenzepine; Receptors, Muscarinic; Salivation; Sympathetic Nervous System | 1988 |
Swallow-evoked peristalsis in opossum esophagus: role of cholinergic mechanisms.
Topics: Animals; Atropine; Deglutition; Esophagus; Evoked Potentials; Female; Gastrointestinal Motility; Male; Metoclopramide; Muscle Contraction; Muscle, Smooth; Opossums; Peristalsis; Physostigmine | 1986 |
Effect of metoclopramide on the absorption of cimetidine in rats.
Topics: Animals; Atropine; Cimetidine; Digestive System; Hydrogen-Ion Concentration; Intestinal Absorption; Kinetics; Male; Metoclopramide; Rats; Rats, Inbred Strains; Regional Blood Flow | 1986 |
Epigastric impedance: a non-invasive method for the assessment of gastric emptying and motility.
Topics: Adult; Atropine; Dye Dilution Technique; Electric Conductivity; Female; Food; Gastric Emptying; Gastrointestinal Motility; Humans; Hydrogen-Ion Concentration; Male; Methods; Metoclopramide; Time Factors | 1985 |
Motor-stimulating properties of cisapride on isolated gastrointestinal preparations of the guinea pig.
Topics: Acetylcholine; Animals; Atropine; Cisapride; Dose-Response Relationship, Drug; Electric Stimulation; Female; Gastrointestinal Motility; Guinea Pigs; Hexamethonium Compounds; In Vitro Techniques; Intestinal Mucosa; Male; Methacholine Chloride; Methacholine Compounds; Metoclopramide; Muscle Contraction; Nicotine; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Tetrodotoxin | 1985 |
Response of isolated renal arterioles to acetylcholine, dopamine, and bradykinin.
Topics: Acetylcholine; Animals; Arterioles; Atropine; Bradykinin; Dopamine; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Metoclopramide; Rabbits; Renal Circulation | 1985 |
Effect of gastrin, histamine, serotonin, and adrenergic amines on gastroesophageal sphincter pressure in the dog.
Topics: Animals; Atropine; Cimetidine; Diphenhydramine; Dogs; Esophagogastric Junction; Fasting; Gastrins; Histamine; Metoclopramide; Pentagastrin; Pressure; Serotonin; Sympathomimetics | 1985 |
[Influence of gastric emptying rate on the absorption of cimetidine in rats].
Topics: Animals; Atropine; Cimetidine; Gastric Emptying; Intestinal Absorption; Male; Metoclopramide; Rats; Rats, Inbred Strains | 1985 |
Abnormal duodenal loop in patients with sliding esophageal hiatal hernia -- studies on intragastric pressure and gastrocolic reflex.
Topics: Adolescent; Adult; Aged; Atropine; Catheterization; Child; Child, Preschool; Colon; Colon, Sigmoid; Congenital Abnormalities; Diverticulum, Colon; Duodenum; Female; Hernia, Diaphragmatic; Hernia, Hiatal; Humans; Male; Metoclopramide; Middle Aged; Pressure; Radiography; Reflex; Sodium Chloride; Stomach | 1974 |
Pharmacological analysis of the effects of metoclopramide on the guinea-pig ileum in vitro.
Topics: Acetylcholine; Animals; Atropine; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Hexamethonium Compounds; Histamine; Ileum; In Vitro Techniques; Methysergide; Metoclopramide; Morphine; Muscle Contraction; Muscle, Smooth; Nicotine; Procaine; Propranolol; Scopolamine; Serotonin; Tetrodotoxin; Time Factors | 1973 |
The premedicant and anti-emetic action of metoclopramide.
Topics: Atropine; Diazepam; Female; Humans; Hypnotics and Sedatives; Meperidine; Metoclopramide; Nausea; Preanesthetic Medication; Vomiting | 1973 |
Effect of intravenous metoclopramide on the incompetent lower esophageal sphincter.
Topics: Atropine; Esophagogastric Junction; Esophagus; Female; Gastroesophageal Reflux; Hernia, Diaphragmatic; Humans; Injections, Intravenous; Male; Manometry; Metoclopramide; Muscles; Muscular Diseases; Posture; Pressure; Radiography | 1974 |
Effect of trimebutine maleate on bethanechol-induced contractions of gastrointestinal tract in conscious and anaesthetized dogs.
Topics: Animals; Atropine; Benzoates; Bethanechol; Bethanechol Compounds; Digestive System Physiological Phenomena; Dogs; Duodenum; Ileum; Injections, Intravenous; Jejunum; Metoclopramide; Muscle Contraction; Muscle, Smooth; Pyloric Antrum; Trimebutine | 1983 |
Are presynaptic dopamine autoreceptors and postsynaptic dopamine receptors in the rabbit caudate nucleus pharmacologically different?
Topics: Acetylcholine; Animals; Apomorphine; Atropine; Carbachol; Caudate Nucleus; Choline; Dopamine; Electric Stimulation; Female; Male; Membrane Potentials; Metoclopramide; Molindone; Physostigmine; Rabbits; Receptors, Dopamine; Sulpiride; Synapses; Synaptic Transmission | 1982 |
A central site of action for benzamide facilitation of gastric emptying.
Topics: Animals; Apomorphine; Atropine; Benzamides; Female; Gastric Emptying; Guinea Pigs; Male; Metoclopramide; Prazosin; Propranolol | 1983 |
Metoclopramide.
Topics: Animals; Atropine; Cat Diseases; Cats; Central Nervous System; Digestive System; Dog Diseases; Dogs; Gastric Emptying; Gastroesophageal Reflux; Humans; Kinetics; Metoclopramide; Muscle, Smooth; Nausea; Vomiting | 1983 |
Effect of metoclopramide on ureteral motility.
Topics: Animals; Atropine; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Humans; In Vitro Techniques; Metoclopramide; Movement; Procaine; Rats; Ureter; Ureteral Obstruction | 1984 |
Pethidine, atropine, metoclopramide and the lower oesophageal sphincter.
Topics: Adult; Atropine; Esophagogastric Junction; Female; Humans; Male; Meperidine; Metoclopramide; Pressure; Time Factors | 1983 |
Metoclopramide and atropine as premedication.
Topics: Atropine; Drug Interactions; Humans; Metoclopramide; Premedication; Preoperative Care | 1982 |
[New method of medicinal treatment of cardiospasm].
Topics: Adult; Aged; Atropine; Delayed-Action Preparations; Dihydroergotamine; Dilatation; Drug Therapy, Combination; Esophageal Achalasia; Humans; Metoclopramide; Middle Aged; Parasympatholytics | 1982 |
Demonstration of specific vascular dopamine receptors mediating vasodilation on the isolated rabbit mesenteric artery.
Topics: Adenosine; Animals; Atropine; Dopamine; Dose-Response Relationship, Drug; Droperidol; Female; In Vitro Techniques; Isoproterenol; Male; Mesenteric Arteries; Metoclopramide; Rabbits; Receptors, Dopamine; Structure-Activity Relationship; Vasodilation | 1981 |
Pathogenesis of diabetic gastroparesis: a pharmacologic study.
Topics: Adult; Atropine; Bethanechol Compounds; Diabetic Neuropathies; Gastric Emptying; Gastrointestinal Motility; Humans; Metoclopramide; Middle Aged; Paralysis; Pyloric Antrum | 1980 |
Metoclopramide and sulpiride as selective blocking agents of pre- and postsynaptic dopamine receptors.
Topics: Aminooxyacetic Acid; Animals; Apomorphine; Atropine; Corpus Striatum; Dopamine; Dopamine Antagonists; Male; Metoclopramide; Norepinephrine; Prazosin; Rats; Receptors, Dopamine; Rotation; Sulpiride | 1980 |
[Drug therapy of gastrointestinal motility disorders].
Topics: Antacids; Atropine; Carbenoxolone; Colonic Diseases, Functional; Deglutition Disorders; Diarrhea; Dumping Syndrome; Gastroesophageal Reflux; Gastrointestinal Motility; Humans; Intestinal Diseases; Metoclopramide; Propranolol; Tolbutamide | 1980 |
Control of gastric emptying in the pig: influence of cholecystokinin, somatostatin and prokinetic agents.
Topics: Animals; Atropine; Cholecystokinin; Cisapride; Eating; Female; Gastric Emptying; Metoclopramide; Piperidines; Somatostatin; Swine | 1995 |
Stimulant effects of 5-hydroxytryptamine on guinea pig stomach preparations in vitro.
Topics: 4-Aminobenzoic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Atropine; Benzamides; Binding Sites; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Indoles; Ligands; Male; Metoclopramide; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; para-Aminobenzoates; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Stomach; Tetrodotoxin; Tropanes; Tropisetron | 1994 |
Effects of cholinoceptor and 5-hydroxytryptamine3 receptor antagonism on erythromycin-induced canine intestinal motility disruption and emesis.
Topics: Animals; Atropine; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cholinergic Antagonists; Dogs; Electromyography; Erythromycin; Female; Gastrointestinal Motility; Hexamethonium; Hexamethonium Compounds; Injections, Intravenous; Intestine, Small; Male; Metoclopramide; Muscle Contraction; Muscle, Smooth; Serotonin Antagonists; Tropanes; Vomiting | 1993 |
[Effect of Y-25130 on gastric motility in anesthetized rats].
Topics: Animals; Antiemetics; Atropine; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Capsaicin; Electric Stimulation; Gastric Balloon; Gastrointestinal Motility; Injections, Intravenous; Male; Metoclopramide; Ondansetron; Oxazines; Rats; Rats, Wistar; Receptors, Serotonin | 1993 |
Anaesthesia and breast feeding.
Topics: Anesthesia, Obstetrical; Anesthetics; Atropine; Breast Feeding; Female; Humans; Infant, Newborn; Metoclopramide; Milk, Human; Neostigmine; Prochlorperazine | 1993 |
Acetaminophen as a marker of gastric emptying in ponies.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Bacterial Agents; Antiemetics; Area Under Curve; Atropine; Erythromycin; Gastric Emptying; Horses; Metoclopramide; Parasympatholytics; Sympatholytics; Yohimbine | 1998 |
Determination of compatibility and stability of drugs used in palliative care.
Topics: Atropine; Butylscopolammonium Bromide; Drug Interactions; Drug Stability; Drug Therapy, Combination; Humans; Metoclopramide; Morphine; Palliative Care; Ranitidine; Terminal Care | 1998 |
Low susceptibility of stress ulcer in diabetic rats: role of cholinergic gastric motility.
Topics: Animals; Antiemetics; Antimetabolites; Atropine; Bethanechol; Blood Glucose; Body Weight; Cholinergic Fibers; Deoxyglucose; Diabetes Mellitus, Experimental; Disease Susceptibility; Drinking Behavior; Gastric Emptying; Gastric Mucosa; Glutathione; Male; Metoclopramide; Parasympatholytics; Parasympathomimetics; Polyuria; Rats; Rats, Wistar; Stomach Ulcer; Stress, Physiological; Vagotomy | 1998 |
Effect of the aqueous extract of xiao-ban-xia-tang on gastric emptying in mice.
Topics: Administration, Oral; Animals; Antiemetics; Atropine; Dopamine; Drugs, Chinese Herbal; Female; Gastric Emptying; Male; Metoclopramide; Mice; Neostigmine; Phytotherapy; Pinellia; Plant Roots; Zingiber officinale | 2002 |
[Choice of optimal vegetotropic drug therapy in patients with chronic non-calculous cholecystitis combined with gallbladder dyskinesia].
Topics: Adolescent; Adult; Atropine; Cholecystitis; Female; Gallbladder; Humans; Male; Metoclopramide; Middle Aged; Propranolol; Ultrasonography | 2002 |
Involvement of cholinergic neurons in the regulation of the ghrelin secretory response to feeding in sheep.
Topics: Animals; Atropine; Cholinergic Agents; Cholinergic Agonists; Cholinergic Antagonists; Eating; Ghrelin; Hexamethonium; Kinetics; Male; Metoclopramide; Neurons; Peptide Hormones; Sheep; Vagus Nerve | 2003 |
[SENSORIMOTOR DISTURBANCES IN DUODENAL ULCER. RADIOLOGIC TEST AND COURSE UNDER METOCLOPRAMIDE].
Topics: Antiemetics; Atropine; Drug Therapy; Duodenal Ulcer; Gastrointestinal Motility; Humans; Metoclopramide; Procainamide; Radiography | 1964 |
Effect of BL-21 (Wei-Yu) acupoint stimulation on gastric motility following preanesthetic treatment in dogs.
Topics: Acepromazine; Acupuncture; Acupuncture Points; Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Animals; Antipsychotic Agents; Atropine; Diazepam; Dogs; Dopamine Antagonists; Electromyography; Gastrointestinal Motility; Hypnotics and Sedatives; Metoclopramide; Parasympatholytics; Preanesthetic Medication; Xylazine | 2000 |
Effect of anticholinergics (atropine, glycopyrrolate) and prokinetics (metoclopramide, cisapride) on gastric motility in beagles and labrador retrievers.
Topics: Animals; Atropine; Body Weight; Breeding; Cisapride; Dogs; Dose-Response Relationship, Drug; Electromyography; Gastric Emptying; Gastrointestinal Agents; Gastrointestinal Motility; Glycopyrrolate; Metoclopramide; Muscarinic Antagonists | 2006 |
The utility of noninvasive (13)C-acetate breath test using a new solid test meal to measure gastric emptying in mice.
Topics: Acetic Acid; Animal Feed; Animals; Atropine; Breath Tests; Carbon Dioxide; Carbon Isotopes; Gastric Emptying; Male; Metoclopramide; Mice; Sensitivity and Specificity | 2008 |
Evaluation of a modified acetaminophen absorption test to estimate the abomasal emptying rate in Holstein-Friesian heifers.
Topics: Abomasum; Absorption; Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Area Under Curve; Atropine; Cattle; Cross-Over Studies; Female; Gastric Emptying; Infusions, Intravenous; Infusions, Subcutaneous; Intestinal Absorption; Metoclopramide; Parasympatholytics; Veterinary Medicine | 2011 |
An in vivo zebrafish screen identifies organophosphate antidotes with diverse mechanisms of action.
Topics: Animals; Antidotes; Atropine; Cell Line, Tumor; Cholinergic Antagonists; Cholinesterase Reactivators; Drug Evaluation, Preclinical; Emetine; Glycopyrrolate; High-Throughput Screening Assays; Humans; Lethal Dose 50; Metoclopramide; Neostigmine; Organophosphates; Parathion; Pirenzepine; Pralidoxime Compounds; Zebrafish | 2013 |