atropine has been researched along with methylprednisolone in 24 studies
| Studies (atropine) | Trials (atropine) | Recent Studies (post-2010) (atropine) | Studies (methylprednisolone) | Trials (methylprednisolone) | Recent Studies (post-2010) (methylprednisolone) |
|---|---|---|---|---|---|
| 26,711 | 1,259 | 1,697 | 20,247 | 2,602 | 5,317 |
| Protein | Taxonomy | atropine (IC50) | methylprednisolone (IC50) |
|---|---|---|---|
| Glucocorticoid receptor | Homo sapiens (human) | 0.011 | |
| Glycine receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | 0.011 | |
| Glycine receptor subunit beta | Rattus norvegicus (Norway rat) | 0.011 | |
| Glycine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | 0.011 | |
| Glycine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | 0.011 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (20.83) | 18.7374 |
| 1990's | 3 (12.50) | 18.2507 |
| 2000's | 8 (33.33) | 29.6817 |
| 2010's | 8 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Azar, A; Makley, TA | 1 |
| McDonnell, PJ; Miller-Scholte, A; Ryan, SJ; Walonker, AF | 1 |
| Chitano, P; Fabbri, LM; Maggi, CA; Mapp, CE; Patacchini, R | 1 |
| Constable, IJ; Hamada, S; Lee, P; Schepens, CL | 1 |
| Johnston, SS; Ware, CF | 1 |
| Kusajima, K; Wax, ST; Webb, WR | 1 |
| Lyne, AJ; Rosen, ES | 1 |
| Dudley, D; Emerick, G; Fineman, MS; Katz, LJ; Maguire, JI | 1 |
| Jokanović, M; Jovanovic, D; Kosanović, M; Maksimović, M; Piperski, V; Stepanović Petrović, RM | 1 |
| David, SU; Dinu, D; Grigorescu, A | 1 |
| Jayapandian, P; Rajasekaran, D; Subbaraghavalu, G | 1 |
| Mustafa, S | 1 |
1 review(s) available for atropine and methylprednisolone
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for atropine and methylprednisolone
| Article | Year |
|---|---|
Prediction of visual acuity recovery in cystoid macular edema.
Topics: Aged; Aged, 80 and over; Atropine; Cataract Extraction; Eyeglasses; Female; Humans; Injections; Macular Edema; Male; Methylprednisolone; Photoreceptor Cells; Prednisolone; Prospective Studies; Vision Tests; Visual Acuity | 1992 |
22 other study(ies) available for atropine and methylprednisolone
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Sympathetic ophthalmia. A long-term follow-up.
Topics: Adolescent; Adult; Atropine; Child; Child, Preschool; Dexamethasone; Drug Therapy, Combination; Eye Injuries; Follow-Up Studies; Humans; Male; Methylprednisolone; Middle Aged; Ophthalmia, Sympathetic; Prednisone; Time Factors; Uvea; Visual Acuity; Wounds, Penetrating | 1978 |
Pharmacological modulation of the contractile response to toluene diisocyanate in the rat isolated urinary bladder.
Topics: Animals; Atropine; Capsaicin; In Vitro Techniques; Indomethacin; Male; Methylprednisolone; Muscle Contraction; Muscle, Smooth; Rats; Rats, Inbred Strains; Ruthenium Red; Tetrodotoxin; Toluene 2,4-Diisocyanate; Urinary Bladder | 1990 |
Experimental vitreous surgery in monkeys. IX. Pars plana approach in open-sky technique.
Topics: Animals; Atropine; Ciliary Body; Disease Models, Animal; Electrocoagulation; Electroretinography; Follow-Up Studies; Haplorhini; Intraocular Pressure; Methods; Methylprednisolone; Mydriatics; Ophthalmic Solutions; Ophthalmoscopy; Oxytetracycline; Phenylephrine; Polymyxins; Postoperative Complications; Sodium Chloride; Suture Techniques; Vitreous Body | 1974 |
Iris involvement in leukaemia.
Topics: Acetazolamide; Atropine; Cerebrospinal Fluid; Child, Preschool; Eye Diseases; Female; Humans; Intraocular Pressure; Iris; Leukemia, Lymphoid; Leukocyte Count; Methylprednisolone; Prednisolone; Uveitis | 1973 |
Effects of methylprednisolone on pulmonary microcirculation.
Topics: Animals; Atropine; Capillaries; Dogs; Female; Furosemide; Hemorrhage; Hypotension; Lung; Male; Methylprednisolone; Microcirculation; Pulmonary Alveoli; Pulmonary Artery; Pulmonary Atelectasis; Pulmonary Circulation; Pulmonary Valve Insufficiency; Pulmonary Veins; Venous Pressure | 1974 |
Still's disease and rheumatoid nodule of the sclera.
Topics: Adult; Arthritis, Juvenile; Atropine; Diplopia; Eye Diseases; Female; Humans; Methylprednisolone; Prednisolone; Rheumatoid Nodule; Sclera; Serologic Tests | 1968 |
Bilateral choroidal effusions and angle-closure glaucoma associated with human immunodeficiency virus infection.
Topics: Anterior Chamber; Atropine; Choroid Diseases; Ciliary Body; Exudates and Transudates; Eye Infections, Viral; Glaucoma, Angle-Closure; Glucocorticoids; HIV Infections; Humans; Intraocular Pressure; Male; Methylprednisolone; Middle Aged; Mydriatics; Ophthalmic Solutions; Prednisolone; Syndrome; Ultrasonography; Uveal Diseases; Visual Acuity | 1997 |
Effects of atropine, trimedoxime and methylprednisolone on the development of organophosphate-induced delayed polyneuropathy in the hen.
Topics: Animals; Ataxia; Atropine; Chickens; Drug Therapy, Combination; Female; Isoflurophate; Methylprednisolone; Movement; Paralysis; Polyneuropathies; Trimedoxime | 2001 |
[Sympathetic ophthalmia, case report].
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Atropine; Diclofenac; Drug Therapy, Combination; Eye Enucleation; Eye Injuries, Penetrating; Humans; Male; Methylprednisolone; Middle Aged; Mydriatics; Ophthalmia, Sympathetic; Ophthalmic Solutions; Recurrence; Treatment Outcome | 2006 |
Guillain-Barre syndrome due to organophosphate compound poison.
Topics: Adult; Atropine; Chlorpyrifos; Cholinesterase Inhibitors; Cholinesterase Reactivators; Gastric Lavage; Guillain-Barre Syndrome; Humans; Insecticides; Male; Methylprednisolone; Neuroprotective Agents; Parasympatholytics; Plasmapheresis; Pralidoxime Compounds | 2009 |
Evaluation of different anti-asthmatic drugs on cooling-induced bronchoconstriction.
Topics: Aminophylline; Animals; Anti-Asthmatic Agents; Atropine; Bronchioles; Bronchoconstriction; Carbachol; Cold Temperature; Cromolyn Sodium; Epinephrine; Isoproterenol; Male; Methylprednisolone; Muscle, Smooth; Sheep; Tissue Culture Techniques; Trachea | 2015 |