atropine has been researched along with methyldopa in 35 studies
Studies (atropine) | Trials (atropine) | Recent Studies (post-2010) (atropine) | Studies (methyldopa) | Trials (methyldopa) | Recent Studies (post-2010) (methyldopa) |
---|---|---|---|---|---|
26,711 | 1,259 | 1,697 | 3,719 | 420 | 143 |
Protein | Taxonomy | atropine (IC50) | methyldopa (IC50) |
---|---|---|---|
Epidermal growth factor receptor | Homo sapiens (human) | 5.228 | |
Tyrosine-protein kinase Fyn | Homo sapiens (human) | 5.176 | |
Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | 2.126 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 18 (51.43) | 18.7374 |
1990's | 2 (5.71) | 18.2507 |
2000's | 6 (17.14) | 29.6817 |
2010's | 9 (25.71) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
Glen, RC; Lowe, R; Mitchell, JB | 1 |
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
Bellman, K; Knegtel, RM; Settimo, L | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Bissett, JK; de Soyza, ND; Kane, JJ; Murphy, ML | 1 |
Gaul, SL; Sweet, CS | 1 |
Sjoerdsma, A | 1 |
Carlsson, A; Carlsson, M; Svensson, A | 1 |
Mehta, VL; Prabhu, S; Valecha, N | 1 |
Fox, GR; Virgo, BB | 1 |
Bivens, LW; Ray, OS | 1 |
Antonaccio, MJ; Burrell, R; Robson, RD | 1 |
Bartholini, G; Pletscher, A | 1 |
Juvancz, P; Káldor, A | 1 |
Bencosme, SA; Berger, JM | 1 |
Walker, JL; Weetman, DF | 1 |
Koe, BK; Weissman, A | 1 |
Schnieden, H; Truslove, GM | 1 |
Gunnar, RM; Loeb, HS; Rahimtoola, SH; Rosen, KM; Sinno, MZ | 1 |
Alberti, PW; Black, JI | 1 |
de Angelis, J | 1 |
SCHNIEDEN, H | 1 |
BARRNETT, RJ; LENTZ, TL | 1 |
APPENZELLER, O; SCHNIEDEN, H | 1 |
Aboul-Enein, HY; Alizadeh, R; Ghassempour, A; Karami, A; Najafi, NM; Römpp, A; Spengler, B | 1 |
3 review(s) available for atropine and methyldopa
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Drugs affecting monoamines in the basal ganglia.
Topics: Amines; Animals; Atropine; Barbiturates; Basal Ganglia; Biogenic Amines; Carbon Isotopes; Chlorpromazine; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Haloperidol; Hydroxyindoleacetic Acid; Methyldopa; Norepinephrine; Phenylacetates; Rabbits; Rats; Tranquilizing Agents; Tritium | 1972 |
Specific granules in mammalian and non-mammalian vertebrate cardiocytes.
Topics: Animals; Atropine; Bethanechol Compounds; Catecholamines; Cats; Cattle; Cytoplasmic Granules; Dihydroxyphenylalanine; Fishes; Heart Atria; Heart Ventricles; Hemicholinium 3; Histocytochemistry; Humans; Isoproterenol; Lysosomes; Methyldopa; Microscopy, Electron; Myocardium; Nialamide; Norepinephrine; Propranolol; Rabbits; Rats; Reserpine; Sympatholytics; Sympathomimetics | 1971 |
1 trial(s) available for atropine and methyldopa
Article | Year |
---|---|
Effect of antihypertensive drugs on the "intrinsic" heart rate.
Topics: Amidines; Antihypertensive Agents; Atropine; Clinical Trials as Topic; Depression, Chemical; Heart Rate; Humans; Methyldopa; Propranolol; Quinolines; Reserpine | 1969 |
31 other study(ies) available for atropine and methyldopa
Article | Year |
---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Electrophysiology of atropine.
Topics: Adult; Aged; Atrioventricular Node; Atropine; Bundle of His; Bundle-Branch Block; Cardiac Catheterization; Electrocardiography; Electrophysiology; Heart; Heart Atria; Heart Conduction System; Heart Diseases; Humans; Hydrochlorothiazide; Hypertension; Methyldopa; Middle Aged; Neural Conduction; Nitroglycerin; Purkinje Fibers; Refractory Period, Electrophysiological; Rheumatic Heart Disease; Tachycardia | 1975 |
Antagonism of conditioned salivation in conscious dogs by antihypertensive drugs.
Topics: Animals; Antihypertensive Agents; Atropine; Carbidopa; Clonidine; Conditioning, Classical; Dogs; Drug Interactions; Female; Male; Methyldopa; Pilocarpine; Salivation | 1977 |
Central action as a key to past and future therapy of hypertension.
Topics: Atropine; Brain; Humans; Hypertension; Methyldopa; Pargyline; Phenobarbital; Propranolol; Receptors, Adrenergic; Research Design | 1977 |
Synergistic interactions between muscarinic antagonists, adrenergic agonists and NMDA antagonists with respect to locomotor stimulatory effects in monoamine-depleted mice.
Topics: Adrenergic alpha-Agonists; Animals; Atropine; Biperiden; Clonidine; Disease Models, Animal; Dizocilpine Maleate; Drug Synergism; Ketamine; Male; Methyldopa; Mice; Mice, Neurologic Mutants; Motor Activity; N-Methylaspartate; Parasympatholytics; Parkinson Disease; Piperazines | 1991 |
Influence of clonidine, methyldopa and propranolol on acute toxicity of fenitrothion in mice.
Topics: Animals; Atropine; Clonidine; Drug Interactions; Fenitrothion; Male; Methyldopa; Mice; Propranolol | 1990 |
The effects of phenobarbital, atropine, L-alpha-methyldopa, and DL-propranolol on dieldrin-induced hyperglycemia in the adult rat.
Topics: Administration, Oral; Animals; Atropine; Blood Glucose; Central Nervous System; Dieldrin; Drug Interactions; Gluconeogenesis; Hypoglycemia; Lethal Dose 50; Liver; Male; Methyldopa; Phenobarbital; Phosphoenolpyruvate Carboxykinase (GTP); Propranolol; Rats; Rats, Inbred Strains | 1985 |
Drug alteration of autonomic function and electroconvulsive shock mortality in rats.
Topics: Animals; Atropine; Autonomic Nervous System; Chlorpromazine; Dibenzylchlorethamine; Electroconvulsive Therapy; Ethanolamines; Heart Rate; Hexamethonium Compounds; Methyldopa; Mortality; Rats; Scopolamine | 1966 |
The effects of L-dopa and alpha-methyldopa on reflexes and sympathetic nerve function.
Topics: Animals; Atropine; Barbiturates; Benserazide; Blood Pressure; Carbidopa; Carotid Arteries; Dogs; Electric Stimulation; Heart Rate; Hindlimb; Levodopa; Methyldopa; Monoamine Oxidase Inhibitors; Neurons; Perfusion; Posture; Reflex; Regional Blood Flow; Sympathetic Nervous System; Vagotomy; Vagus Nerve | 1974 |
Oxotremorine-induced hypertension in the anaesthetized rat.
Topics: Adrenal Glands; Animals; Atropine; Blood Pressure; Central Nervous System; Cordotomy; Female; Guanethidine; Heart Rate; Hypertension; Male; Methyldopa; Pentolinium Tartrate; Phentolamine; Pyrrolidinones; Rats; Reserpine; Stimulation, Chemical; Sympathetic Nervous System; Vagotomy | 1970 |
m-Fluorotyrosine convulsions and mortality: relationship to catecholamine and citrate metabolism.
Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Anticonvulsants; Atropine; Azoles; Brain; Chlordiazepoxide; Chlorpromazine; Citrates; Dihydroxyphenylalanine; Disulfiram; Drug Antagonism; Drug Synergism; Kidney; Lysergic Acid Diethylamide; Male; Methyldopa; Mice; Morphine; Nialamide; Norepinephrine; Pargyline; Phenobarbital; Phenytoin; Reserpine; Seizures; Serotonin; Strychnine; Tetrabenazine; Trimethadione; Tyrosine; Urea | 1967 |
The effect of some drugs on genetic tremor in the mouse.
Topics: Acetylcholine; Age Factors; Animals; Atropine; Barbiturates; Behavior, Animal; Body Weight; Brain; Brain Chemistry; Dopamine; Female; Genetics; Histocytochemistry; Male; Methyldopa; Mice; Norepinephrine; Orphenadrine; Scopolamine; Serotonin; Tremor | 1970 |
Cardiac conduction in patients with symptomatic sinus node disease.
Topics: Aged; Arrhythmia, Sinus; Atropine; Bundle-Branch Block; Digoxin; Electrocardiography; Female; Heart Block; Heart Conduction System; Heart Rate; Humans; Male; Methyldopa; Middle Aged; Pacemaker, Artificial; Sinoatrial Node | 1971 |
Iatrogenic symptoms in otolaryngology.
Topics: Adult; Aged; Anti-Bacterial Agents; Anticonvulsants; Antidepressive Agents; Antihypertensive Agents; Atropine; Contraceptives, Oral; Deafness; Drug-Related Side Effects and Adverse Reactions; Epistaxis; Female; Glutethimide; Humans; Iatrogenic Disease; Male; Methyldopa; Middle Aged; Monoamine Oxidase Inhibitors; Nose Diseases; Otorhinolaryngologic Diseases; Pharyngitis; Salivary Gland Diseases; Sinusitis; Tinnitus; Vertigo | 1968 |
Hemodynamic monitoring in the operating room.
Topics: Atropine; Cardiac Catheterization; Ephedrine; Hemodynamics; Homeostasis; Humans; Intraoperative Care; Intraoperative Complications; Methyldopa; Monitoring, Physiologic; Nitroglycerin; Nitroprusside; Operating Rooms; Phenylephrine; Positive-Pressure Respiration; Propranolol | 1984 |
EFFECT OF ALPHA METHYL DOPA ON EXPERIMENTAL TREMOR.
Topics: 5-Hydroxytryptophan; Atropine; Electrophysiological Phenomena; Electrophysiology; Equipment and Supplies; Heterocyclic Compounds; Hypnotics and Sedatives; Indoles; Methamphetamine; Methyldopa; Mice; Nicotine; Parasympatholytics; Research; Toxicology; Tremor | 1963 |
THE ROLE OF THE NERVOUS SYSTEM IN REGENERATING HYDRA: THE EFFECT OF NEUROPHARMACOLOGICAL AGENTS.
Topics: Amphetamine; Amphetamines; Animals; Atropine; Autonomic Agents; Biphenyl Compounds; Chlorpromazine; Cnidaria; Decamethonium Compounds; Dihydroxyphenylalanine; Enzyme Inhibitors; Ergotamine; Hexamethonium Compounds; Histocytochemistry; Histology; Hydra; Isoflurophate; Lidocaine; Methyldopa; Nervous System; Pharmacology; Physostigmine; Regeneration; Research; Reserpine; Tubocurarine | 1963 |
EFFECT OF SOME DRUGS ON REFLEX VASODILATATION OF HAND PRODUCED BY RADIANT HEATING OF TRUNK.
Topics: Atropine; Bretylium Compounds; Hand; Heating; Hot Temperature; Humans; Methyldopa; Pharmacology; Phenoxybenzamine; Reflex; Sensory Receptor Cells; Sympatholytics; Vasodilation; Vasomotor System | 1964 |
Crystalline degradation products of vancomycin as chiral stationary phase in microcolumn liquid chromatography.
Topics: Alanine; Atropine; Biotransformation; Chromatography, High Pressure Liquid; Chromatography, Liquid; Crystallization; Methyldopa; Microchemistry; Particle Size; Phenylalanine; Propranolol; Silicon Dioxide; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Vancomycin | 2008 |