atropine has been researched along with methotrimeprazine in 15 studies
| Studies (atropine) | Trials (atropine) | Recent Studies (post-2010) (atropine) | Studies (methotrimeprazine) | Trials (methotrimeprazine) | Recent Studies (post-2010) (methotrimeprazine) |
|---|---|---|---|---|---|
| 26,711 | 1,259 | 1,697 | 816 | 57 | 60 |
| Protein | Taxonomy | atropine (IC50) | methotrimeprazine (IC50) |
|---|---|---|---|
| Pleiotropic ABC efflux transporter of multiple drugs | Saccharomyces cerevisiae S288C | 9.6 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (46.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (33.33) | 29.6817 |
| 2010's | 3 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Dahlerup, J | 1 |
| Guillen, JC; Jouve, R; Langlet, F; Noirclerc, M; Puddu, PE; Reale, A; Torresani, J | 1 |
| Bass, P; Kennedy, JA; Wiley, JN | 1 |
| Kocher, R; Rohrer, G | 1 |
| Ishiwata, T; Shibata, K; Yoshida, K | 1 |
| Fujimori, M; Hayashi, A; Nakamura, K; Okuma, T | 1 |
| Camacho, AA; Ishiy, HM; Júnior, JR; Luna, SP; Massone, F; Neto, FJ | 1 |
| CLARKE, RS; DUNDEE, JW; LOVE, WJ; MOORE, J; NICHOLL, RM | 1 |
1 trial(s) available for atropine and methotrimeprazine
| Article | Year |
|---|---|
[Treatment of severe chronic pains with a combination of thymoleptics and neuroleptics (author's transl)].
Topics: Adult; Antidepressive Agents; Atropine; Chlorpromazine; Clinical Trials as Topic; Clomipramine; Drug Combinations; Female; Haloperidol; Humans; Imipramine; Male; Methotrimeprazine; Middle Aged; Morphine; Neoplasms; Pain; Papaverine; Tranquilizing Agents | 1974 |
14 other study(ies) available for atropine and methotrimeprazine
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
[Drugs in acute heart disease. 2].
Topics: Atropine; Heart Diseases; Humans; Metaproterenol; Methotrimeprazine | 1985 |
[An anesthetic technic in dogs for studying the arrhythmogenic effects of acute coronary occlusion].
Topics: Anesthesia, General; Animals; Arrhythmias, Cardiac; Atropine; Coronary Disease; Coronary Vessels; Disease Models, Animal; Dogs; Electrocardiography; Female; Ligation; Male; Methotrimeprazine; Pancuronium; Pentobarbital; Preanesthetic Medication | 1985 |
Measurement of fecal output in rats.
Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Apomorphine; Atropine; Chlorpromazine; Codeine; Cyclazocine; Digestive System; Feces; Housing, Animal; Levallorphan; Magnesium Sulfate; Male; Mecamylamine; Meperidine; Methotrimeprazine; Methylamines; Mineral Oil; Morphine; Muscle, Smooth; Opium; Papaverine; Pentazocine; Rats | 1972 |
[The time factor in injectable preparations. I].
Topics: Atropine; Chlorpromazine; Chromatography, Thin Layer; Drug Stability; Hot Temperature; Injections; Light; Methotrimeprazine; Pilocarpine; Procaine; Solutions; Time Factors | 1969 |
The effect of some psychotropic drugs on the electric activity of the brain and sleep cycle pattern of the cat.
Topics: Animals; Antidepressive Agents; Atropine; Brain; Cats; Chlordiazepoxide; Chlorpromazine; Electroencephalography; Electromyography; Electrooculography; Electrophysiology; Imipramine; Methotrimeprazine; Neostigmine; Pentobarbital; Perphenazine; Reserpine; Sleep; Tranquilizing Agents | 1967 |
The effects of atropine and methotrimeprazine on the epinephrine-induced arrhythmias in halothane-anesthetized dogs.
Topics: Analgesics, Non-Narcotic; Anesthetics, Inhalation; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Blood Pressure; Dog Diseases; Dogs; Electrocardiography; Epinephrine; Female; Halothane; Heart Rate; Infusions, Parenteral; Male; Methotrimeprazine; Random Allocation | 2001 |
STUDIES OF DRUGS GIVEN BEFORE ANAESTHESIA. VI. THE PHENOTHIAZINE DERIVATIVES.
Topics: Anesthesia; Anesthesia, General; Atropine; Chlorpromazine; Chlorprothixene; Fluphenazine; Humans; Meperidine; Methohexital; Methotrimeprazine; Nitrous Oxide; Oxygen; Perphenazine; Pharmacology; Phenothiazines; Preanesthetic Medication; Prochlorperazine; Promazine; Promethazine; Thiazines; Thiethylperazine; Toxicology; Tranquilizing Agents; Trifluoperazine; Triflupromazine; Trimeprazine | 1965 |