atropine has been researched along with methoctramine in 83 studies
| Studies (atropine) | Trials (atropine) | Recent Studies (post-2010) (atropine) | Studies (methoctramine) | Trials (methoctramine) | Recent Studies (post-2010) (methoctramine) |
|---|---|---|---|---|---|
| 26,711 | 1,259 | 1,697 | 40 | 0 | 15 |
| 26,711 | 1,259 | 1,697 | 332 | 1 | 32 |
| Protein | Taxonomy | atropine (IC50) | methoctramine (IC50) |
|---|---|---|---|
| Cholinesterase | Homo sapiens (human) | 0.9772 | |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 0.0407 | |
| Acetylcholinesterase | Homo sapiens (human) | 5.3703 | |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | 0.138 | |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | 0.138 | |
| Carboxylic ester hydrolase | Rattus norvegicus (Norway rat) | 0.9772 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (9.64) | 18.7374 |
| 1990's | 39 (46.99) | 18.2507 |
| 2000's | 25 (30.12) | 29.6817 |
| 2010's | 10 (12.05) | 24.3611 |
| 2020's | 1 (1.20) | 2.80 |
| Authors | Studies |
|---|---|
| Bonner, TI; Brann, MR; Buckley, CM; Buckley, NJ | 1 |
| Angeli, P; Brasili, L; Giardinà, D; Melchiorre, C; Picchio, MT; Quaglia, W | 1 |
| Kovacs, I; Roeske, WR; Varga, EV; Waite, SL; Yamamura, HI | 1 |
| Bolognesi, ML; Budriesi, R; Chiarini, A; Ghelardini, C; Melchiorre, C; Minarini, A; Rosini, M; Tumiatti, V; Wade, EJ | 1 |
| Challiss, RA; Nahorski, SR; Nelson, CP | 1 |
| Bellucci, C; Buccioni, M; Ghelardini, C; Marucci, G; Melchiorre, C; Milelli, A; Minarini, A; Rosini, M; Tumiatti, V | 1 |
| Bhattacharjee, AK; Evans, SA; Gordon, RK; Pervitsky, D; Pomponio, JW | 1 |
| Cassinelli, A; Melchiorre, C; Quaglia, W | 1 |
| Bauer, C; Caldwell, L; Kinnier, WJ; Lancaster, J; McMillan, B; Price, CH; Sweetnam, PM | 1 |
| Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K | 1 |
| Sastry, BV; Stephan, CC | 1 |
| Cost, M; Majewski, H | 1 |
| Jaiswal, N; Lambrecht, G; Malik, KU; Mutschler, E; Tacke, R | 1 |
| Angeli, P; Brasili, L; Cingolani, ML; Marucci, G; Pigini, P; Tonnini, MC | 1 |
| Yang, CM | 1 |
| McLeskey, SW; Wojcik, WJ | 1 |
| Alonso, R; Didier, M; Soubrie, P | 1 |
| el-Fakahany, EE; Lee, NH | 1 |
| Kenimer, JG; Takashima, A | 1 |
| el-Fakahany, EE; Forray, C; Lee, NH | 1 |
| Angeli, P; Lambrecht, G; Melchiorre, C; Moser, U; Mutschler, E; Wess, J | 1 |
| Ortegón, ME; Raffa, RB; Watson, M | 1 |
| Angeli, P; Lambrecht, G; Melchiorre, C; Mutschler, E; Picchio, MT; Wess, J | 1 |
| Nakamura, K; Okuma, Y; Osumi, Y; Yokotani, K | 1 |
| Eglen, RM; Ford, AP; Reddy, H; Watson, N | 1 |
| Howell, RE; Kovalsky, MP | 1 |
| Imaizumi, Y; Tanaka, M; Watanabe, M; Yamahara, NS | 1 |
| Ballabeni, V; Barocelli, E; Caretta, A; Chiavarini, M; Impicciatore, M; Molina, E | 1 |
| Howell, RE; Kovalsky, MP; Laemont, KD | 1 |
| Bissonnette, BM; Brasitus, TA; Khare, S; Sitrin, MD; Tien, XY; Wali, RK; Wilson, D | 1 |
| Davenport, TA; Fukumoto, Y; Gousse, A; Kamai, T; Latifpour, J; Weiss, RM; Yoshida, M | 1 |
| De Klippel, N; Ebinger, G; Michotte, Y; Sarre, S | 1 |
| Eglen, RM; Harris, GC | 1 |
| Osumi, Y; Yokotani, K | 1 |
| Acs, Z; Makara, GB; Pintér, I | 1 |
| Latifpour, J; Mutoh, S; Saito, M; Weiss, RM | 1 |
| Janković, SM; Milovanović, DR | 1 |
| Levin, RJ; Przyborski, SA | 1 |
| Semba, K; White, TD | 1 |
| Hoover, DB; Neely, DA | 1 |
| Hendrix, PK; Robinson, EP | 1 |
| Abdollahi, M; Dehpour, AR; Kebriaeezadeh, A; Mohammad, M; Samini, M; Sharifzadeh, M | 1 |
| Baba, H; Goldstein, PA; Kohno, T; Okamoto, M; Shimoji, K; Yoshimura, M | 1 |
| Harsing, LG; Zigmond, MJ | 1 |
| Eguchi, T; Ishida, H; Ishikawa, Y; Skowronski, MT | 1 |
| Tobin, G | 1 |
| Brefel-Courbon, C; Freslon, JL; Lazartigues, E; Montastruc, JL; Pelat, M; Rascol, O; Tellioglu, T; Tran, MA | 1 |
| Pagano, AP; Parkman, HP; Ryan, JP | 1 |
| Belmonte, KE; Costello, RW; Evans, CM; Fryer, AD; Gleich, GJ; Jacoby, DB; Yost, BL | 1 |
| Bernardi, G; Bonci, A; Grillner, P; Mercuri, NB; Svensson, TH | 1 |
| Goldie, RG; Preuss, JM | 1 |
| Gharib, C; Lazartigues, E; Montastruc, JL; Montastruc, P; Pelat, M; Rascol, O; Tran, MA | 1 |
| Halayko, AJ; Kahraman, S; Mitchell, RW; Solway, J; Wylam, ME | 1 |
| Chang, KC; Chen, CL; Chiu, TH; Yang, YR | 1 |
| Daniels, DV; Eglen, RM; Ford, AP; Hegde, SS; Meloy, TD | 1 |
| Dohi, S; Ishizawa, Y; Ma, HC; Wang, YF; Yanagidate, F | 1 |
| Herzog, M; Liu, J; Scherer, EQ; Scofield, MA; Shimozono, M; Wangemann, P | 1 |
| Avellar, MC; Guaze, EF; Maróstica, E; Porto, CS | 1 |
| Grbović, L; Jovanović, A; Pesić, S | 2 |
| Goodhead, LH; Mitchell, SN; Moss, S; Sharott, A | 1 |
| Abe, K; Chikuma, T; Hojyo, H; Kato, M; Miyatake, T; Taguchi, K; Utsunomiya, I | 1 |
| Aita, T; Ishihata, A; Katano, Y; Tezuka, A | 1 |
| Jankovic, SM; Jankovic, SV; Protic, BA | 1 |
| Ando, S; Harasawa, I; Honda, K; Kamiya, HO; Koga, K; Takano, Y | 1 |
| Funakami, Y; Hata, T; Itoh, E | 1 |
| Avellar, MC; Maróstica, E; Porto, CS; Siu, ER; Yasuhara, F | 1 |
| Gobbi, MD; Hita, FJ; Pujol Lereis, VA; Rodriguez, MC; Rothlin, RP; Verdi, MG | 1 |
| Eguchi, K; Ohtubo, Y; Yoshii, K | 1 |
| Huang, TJ; Ko, WC; Lin, LH; Lin, YL; Wang, SH; Wu, SN | 1 |
| Advenier, C; Chen, HZ; Cui, YY; Devillier, P; Wang, H; Zhu, L | 1 |
| Djokic, J; Grbovic, L; Nikolic, V; Pesic, S; Stoiljkovic, M | 1 |
| Bae, H; Choi, SM; Kim, HN; Kim, SK; Koo, S; Min, BI; Park, JH; Sun, B | 1 |
| Dentcheva, E; Gautam, D; Potluri, S; Rich, MM; Son, YJ; Tessler, A; Wang, X; Wess, J; Wright, MC | 1 |
| Besalduch, N; Garcia, N; Lanuza, MA; Santafé, MM; Tomàs, J; Tomàs, M | 1 |
| Chess-Williams, R; Moro, C; Uchiyama, J | 1 |
| Chancellor, MB; Hirao, Y; Kita, M; Matsumoto, Y; Miyazato, M; Yokoyama, H; Yoshimura, N | 1 |
| Alves-Do-Prado, W; Ambiel, CR; Antônio, MB; Correia-de-Sá, P; de Paula Ramos, E | 1 |
| Killi, UK; Kuca, K; Soukup, O; Tobin, G; Winder, M; Wsol, V | 1 |
| Anglister, L; Cherniak, M; Etlin, A; Finkel, E; Lev-Tov, A; Mor, Y | 1 |
| Deng, J; Li, L; Shi, C; Song, B; Wu, Y; Zhang, X | 1 |
| Giglio, D; Mukanyangezi, MF; Nieto-Marín, P; Podmolíková, L | 1 |
| Lenina, OA; Petrov, KA | 1 |
1 review(s) available for atropine and methoctramine
| Article | Year |
|---|---|
The role of receptor binding in drug discovery.
Topics: Animals; Drug Design; Humans; Receptors, Drug | 1993 |
82 other study(ies) available for atropine and methoctramine
| Article | Year |
|---|---|
Antagonist binding properties of five cloned muscarinic receptors expressed in CHO-K1 cells.
Topics: Animals; Cell Line; Cloning, Molecular; Cricetinae; Humans; Kinetics; N-Methylscopolamine; Parasympatholytics; Rats; Receptors, Muscarinic; Scopolamine Derivatives | 1989 |
Structure-activity relationships among methoctramine-related polymethylene tetraamines. Chain-length and substituent effects on M-2 muscarinic receptor blocking activity.
Topics: Animals; Carbachol; Chemical Phenomena; Chemistry; Diamines; Guinea Pigs; In Vitro Techniques; Male; Parasympatholytics; Polyamines; Rats; Receptors, Muscarinic; Structure-Activity Relationship | 1989 |
Pharmacological comparison of the cloned human and rat M2 muscarinic receptor genes expressed in the murine fibroblast (B82) cell line.
Topics: Amino Acid Sequence; Animals; Carbachol; Cloning, Molecular; Cyclic AMP; Humans; Mice; Molecular Sequence Data; Muscarinic Agonists; Muscarinic Antagonists; Phosphatidylinositols; Radioligand Assay; Rats; Receptors, Muscarinic; Sequence Alignment; Sequence Homology, Amino Acid; Signal Transduction; Species Specificity | 1998 |
Design, synthesis, and biological activity of methoctramine-related polyamines as putative G(i) protein activators.
Topics: Animals; Atrial Function; CHO Cells; Cricetinae; Diamines; Drug Design; Electric Stimulation; GTP-Binding Protein alpha Subunits, Gi-Go; Guinea Pigs; Heart Atria; Humans; In Vitro Techniques; Muscarinic Agonists; Polyamines; Rats; Receptors, Muscarinic; Structure-Activity Relationship | 2001 |
Constitutive activity and inverse agonism at the M2 muscarinic acetylcholine receptor.
Topics: Animals; Cell Membrane; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Immunoblotting; Inositol Phosphates; Ligands; Muscarinic Agonists; Mutagenesis, Site-Directed; Radioligand Assay; Receptor, Muscarinic M2; Transfection | 2006 |
Structure-activity relationships of methoctramine-related polyamines as muscarinic antagonist: effect of replacing the inner polymethylene chain with cyclic moieties.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Butyrylcholinesterase; Cerebral Cortex; CHO Cells; Cholinesterase Inhibitors; Cricetinae; Cricetulus; Diamines; Drug Design; Drug Evaluation, Preclinical; Guinea Pigs; Heart Atria; Humans; Ileum; Male; Mice; Molecular Structure; Muscarinic Antagonists; Muscle, Skeletal; Parietal Lobe; Photoaffinity Labels; Polyamines; Rabbits; Radioligand Assay; Rats; Receptors, Muscarinic; Structure-Activity Relationship; Vas Deferens | 2007 |
Discovery of subtype selective muscarinic receptor antagonists as alternatives to atropine using in silico pharmacophore modeling and virtual screening methods.
Topics: Atropine; Computer Simulation; Drug Discovery; Humans; Models, Molecular; Molecular Structure; Receptor, Muscarinic M1; Structure-Activity Relationship | 2013 |
Differential blockade of muscarinic receptor subtypes by polymethylene tetraamines. Novel class of selective antagonists of cardiac M-2 muscarinic receptors.
Topics: Animals; Guinea Pigs; Ileum; Indicators and Reagents; Kinetics; Male; Muscle, Smooth; Muscles; Myocardium; Polyamines; Ranidae; Receptors, Muscarinic; Receptors, Nicotinic; Structure-Activity Relationship; Urinary Bladder; Vas Deferens | 1987 |
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes, Liver; Neuralgia; Nociceptin Receptor; Pyrroles; Rats; Receptors, Opioid; Structure-Activity Relationship | 2010 |
Characterization of the subtype of muscarinic receptor coupled to the stimulation of phosphoinositide hydrolysis in 132-1N1 human astrocytoma cells.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Astrocytoma; Atropine; Carbachol; Diamines; Humans; Hydrolysis; Parasympathomimetics; Phosphatidylinositols; Piperidines; Pirenzepine; Receptors, Muscarinic; Scopolamine; Tumor Cells, Cultured | 1992 |
Evidence for facilitatory and inhibitory muscarinic receptors on postganglionic sympathetic nerves in mouse isolated atria.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Atropine; Carbachol; Cocaine; Diamines; Dicyclomine; Female; Heart; Hexamethonium Compounds; In Vitro Techniques; Mice; Myocardium; Nerve Endings; Neurons; Norepinephrine; Parasympatholytics; Pirenzepine; Receptors, Muscarinic; Sympathetic Nervous System; Synaptic Transmission | 1991 |
Pharmacological characterization of the vascular muscarinic receptors mediating relaxation and contraction in rabbit aorta.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Antihypertensive Agents; Aorta, Abdominal; Arecoline; Atropine; Diamines; Endothelium, Vascular; Hexamethonium; Hexamethonium Compounds; Indomethacin; Male; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Norepinephrine; Parasympatholytics; Piperidines; Pirenzepine; Rabbits; Receptors, Muscarinic | 1991 |
Pharmacological characterization of muscarinic receptor subtypes in rabbit isolated tissue preparations.
Topics: Animals; Aorta, Thoracic; Atropine; Diamines; Jejunum; Male; Muscarinic Antagonists; Muscle Contraction; Myocardium; Parasympatholytics; Piperidines; Pirenzepine; Rabbits; Receptors, Muscarinic; Vas Deferens; Vasodilation | 1991 |
Characterization of muscarinic receptors in dog tracheal smooth muscle cells.
Topics: Animals; Atropine; Carbachol; Diamines; Dogs; In Vitro Techniques; Kinetics; Muscle, Smooth; N-Methylscopolamine; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Trachea | 1991 |
Identification of muscarinic receptor subtypes present in cerebellar granule cells: prevention of [3H]propylbenzilyl choline mustard binding with specific antagonists.
Topics: Adenylyl Cyclase Inhibitors; Animals; Atropine; Cell Membrane; Cells, Cultured; Cerebellum; Diamines; Electrophoresis, Polyacrylamide Gel; Parasympatholytics; Pirenzepine; Propylbenzilylcholine Mustard; Quinuclidines; Receptors, Muscarinic; Xanthenes | 1990 |
[3H]N-methylscopolamine binding studies reveal M2 and M3 muscarinic receptor subtypes on cerebellar granule cells in primary culture.
Topics: Animals; Atropine; Binding, Competitive; Cell Survival; Cells, Cultured; Cerebellum; Diamines; Granulocytes; N-Methylscopolamine; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Tritium | 1990 |
The allosteric binding profile of himbacine: a comparison with other cardioselective muscarinic antagonists.
Topics: Alkaloids; Allosteric Regulation; Animals; Atropine; Binding, Competitive; Diamines; Dose-Response Relationship, Drug; Furans; Gallamine Triethiodide; Male; Myocardium; N-Methylscopolamine; Naphthalenes; Piperidines; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives | 1990 |
Muscarinic-stimulated norepinephrine release and phosphoinositide hydrolysis in PC12 cells are independent events.
Topics: Adrenal Gland Neoplasms; Animals; Atropine; Cell Line; Diamines; Hydrolysis; Kinetics; Methacholine Chloride; Methacholine Compounds; Norepinephrine; Parasympathomimetics; Pheochromocytoma; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Pirenzepine; Rats; Receptors, Muscarinic | 1989 |
Methoctramine, a cardioselective muscarinic antagonist, stimulates phosphoinositide hydrolysis in rat cerebral cortex.
Topics: Animals; Atropine; Carbachol; Cerebral Cortex; Diamines; Hydrolysis; In Vitro Techniques; Male; Parasympatholytics; Phosphatidylinositols; Rats; Rats, Inbred Strains | 1989 |
Methoctramine selectively blocks cardiac muscarinic M2 receptors in vivo.
Topics: Animals; Atropine; Blood Pressure; Diamines; Heart Rate; Male; Methacholine Chloride; Methacholine Compounds; Muscarine; Myocardium; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1988 |
Reciprocal hindlimb scratching and putative subtype-selective muscarinic agents.
Topics: Animals; Atropine; Binding Sites; Diamines; Dose-Response Relationship, Drug; Drug Antagonism; Hindlimb; Injections, Spinal; Male; Mice; Parasympathomimetics; Pilocarpine; Receptors, Muscarinic; Succinimides; Trihexyphenidyl | 1988 |
Antimuscarinic action of methoctramine, a new cardioselective M-2 muscarinic receptor antagonist, alone and in combination with atropine and gallamine.
Topics: Animals; Atropine; Carbachol; Diamines; Drug Interactions; Gallamine Triethiodide; Guinea Pigs; Heart Atria; Ileum; In Vitro Techniques; Muscle Contraction; Myocardial Contraction; Rats; Receptors, Muscarinic | 1987 |
Release of endogenous acetylcholine from a vascularly perfused rat stomach in vitro; inhibition by M3 muscarinic autoreceptors and alpha-2 adrenoceptors.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Adrenergic alpha-Antagonists; Animals; Atropine; Calcium; Clonidine; Diamines; Drug Interactions; Electric Stimulation; Gastric Mucosa; Hexamethonium; Hexamethonium Compounds; Male; Muscarinic Antagonists; Oxotremorine; Parasympatholytics; Perfusion; Phenylephrine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Stomach; Sympathetic Nervous System; Tetrodotoxin; Vagus Nerve | 1993 |
Characterization of the interaction between muscarinic M2 receptors and beta-adrenoceptor subtypes in guinea-pig isolated ileum.
Topics: Adrenergic beta-Agonists; Animals; Atropine; Cyclic AMP; Diamines; Dioxolanes; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; Male; Muscle, Smooth; Parasympatholytics; Receptors, Muscarinic | 1995 |
Hypotensive effect of an M2-selective muscarinic antagonist in anaesthetized guinea-pigs.
Topics: Animals; Atropine; Blood Pressure; Depression, Chemical; Diamines; Guinea Pigs; Heart Rate; Male; Muscarinic Antagonists; Norepinephrine; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic | 1995 |
Pertussis toxin-sensitive muscarinic relaxation in the rat iris dilator muscle.
Topics: Acetylcholine; Alkaloids; Animals; Atropine; Diamines; Dose-Response Relationship, Drug; Furans; GTP-Binding Proteins; In Vitro Techniques; Iris; Male; Microinjections; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naphthalenes; Parasympatholytics; Pertussis Toxin; Phentolamine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Virulence Factors, Bordetella | 1995 |
Regional differences in motor responsiveness to antimuscarinic drugs in rabbit isolated small and large intestine.
Topics: Animals; Atropine; Benzodiazepinones; Diamines; Dose-Response Relationship, Drug; Gastrointestinal Motility; Intestine, Large; Intestine, Small; Male; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Rabbits; Receptors, Muscarinic | 1995 |
Methoctramine induces nonspecific airway hyperresponsiveness in vivo.
Topics: Aerosols; Albuterol; Animals; Arachidonic Acid; Atropine; Bronchial Hyperreactivity; Bronchoconstriction; Diamines; Drug Synergism; Gallamine Triethiodide; Guinea Pigs; Histamine; Male; Muscarinic Antagonists; Ovalbumin; Parasympatholytics; Piperazines; Piperidines; Platelet Activating Factor; Propranolol; Receptors, Muscarinic | 1994 |
Vitamin D status modulates rat colonic M3 muscarinic receptor characteristics and coupling to guanylate cyclase.
Topics: Animals; Atropine; Colon; Diamines; Enzyme Activation; Guanylate Cyclase; Male; Muscarinic Antagonists; Nutritional Status; Parasympatholytics; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Vitamin D | 1994 |
Diabetes-induced alterations in the properties of muscarinic cholinergic receptors in rat vas deferens.
Topics: Animals; Atropine; Binding, Competitive; Diabetes Mellitus, Experimental; Diamines; Insulin; Male; Parasympatholytics; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Up-Regulation; Vas Deferens | 1994 |
Effect of M1- and M2-muscarinic drugs on striatal dopamine release and metabolism: an in vivo microdialysis study comparing normal and 6-hydroxydopamine-lesioned rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Atropine; Carbachol; Corpus Striatum; Diamines; Dopamine; Homovanillic Acid; Male; Microdialysis; Oxidopamine; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Reference Values | 1993 |
Selective inactivation of muscarinic M2 and M3 receptors in guinea-pig ileum and atria in vitro.
Topics: Alkylating Agents; Animals; Atropine; Diamines; Dioxolanes; Diphenylacetic Acids; Guinea Pigs; Heart; Heart Atria; Ileum; In Vitro Techniques; Isometric Contraction; Male; Muscarinic Antagonists; Muscle, Smooth; Parasympatholytics; Phenoxybenzamine; Pilocarpine; Piperidines; Receptors, Muscarinic | 1993 |
Cholinergic M2 muscarinic receptor-mediated inhibition of endogenous noradrenaline release from the isolated vascularly perfused rat stomach.
Topics: Animals; Arteries; Atrial Function; Atropine; Depression, Chemical; Diamines; Electric Stimulation; Ethylmaleimide; Heart Atria; Male; Myocardial Contraction; Nerve Endings; Norepinephrine; Oxotremorine; Parasympatholytics; Perfusion; Pertussis Toxin; Phentolamine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Stomach; Sympathetic Nervous System; Vagus Nerve; Virulence Factors, Bordetella | 1993 |
Acetylcholine stimulates growth hormone secretion in the neonatal rat pituitary.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Age Factors; Animals; Animals, Newborn; Atropine; Diamines; Dose-Response Relationship, Drug; Female; Growth Hormone; Male; Muscarinic Agonists; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Pituitary Gland; Rats; Rats, Wistar | 1996 |
Evidence for the presence of regional differences in the subtype specificity of muscarinic receptors in rabbit lower urinary tract.
Topics: Animals; Atropine; Carbachol; Diamines; Female; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Pirenzepine; Rabbits; Receptors, Muscarinic; Species Specificity; Urethra; Urinary Bladder | 1997 |
Pharmacologic characterization of muscarine receptor subtypes in rat gastric fundus mediating contractile responses.
Topics: Acetylcholine; Animals; Atropine; Diamines; Female; Gastric Fundus; Gastrointestinal Motility; Male; Muscarinic Antagonists; Piperazines; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic | 1997 |
Cholinergic modulation of electrogenic ion transport in different regions of the rat small intestine.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Analysis of Variance; Animals; Atropine; Bethanechol; Carbachol; Chlorides; Diamines; Duodenum; Ileum; Intestinal Mucosa; Ion Transport; Jejunum; Male; Muscarinic Agonists; Muscarinic Antagonists; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M3; Receptors, Muscarinic; Structure-Activity Relationship; Tetrodotoxin | 1997 |
M3 muscarinic receptor-mediated enhancement of NMDA-evoked adenosine release in rat cortical slices in vitro.
Topics: Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Atropine; Carbachol; Cerebral Cortex; Diamines; Drug Synergism; In Vitro Techniques; Kinetics; Magnesium; Male; Muscarinic Agonists; Muscarinic Antagonists; N-Methylaspartate; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M3; Receptors, Muscarinic | 1997 |
Differentiation of muscarinic receptors mediating negative chronotropic and vasoconstrictor responses to acetylcholine in isolated rat hearts.
Topics: Acetylcholine; Animals; Atropine; Coronary Vessels; Depression, Chemical; Diamines; Heart Rate; In Vitro Techniques; Male; Pertussis Toxin; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Vasoconstriction; Virulence Factors, Bordetella | 1997 |
Effects of a selective and a nonselective muscarinic cholinergic antagonist on heart rate and intestinal motility in dogs.
Topics: Animals; Atropine; Cross-Over Studies; Diamines; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Female; Gastrointestinal Motility; Heart Rate; Injections, Intramuscular; Injections, Intravenous; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Regression Analysis; Tachycardia | 1997 |
Alterations of physostigmine-induced yawning by chronic lithium administration in rats.
Topics: Animals; Antimanic Agents; Atropine; Diamines; Dose-Response Relationship, Drug; Drug Synergism; Injections, Intraperitoneal; Injections, Intraventricular; Lithium Chloride; Male; Muscarinic Antagonists; Parasympatholytics; Physostigmine; Pirenzepine; Rats; Yawning | 1997 |
Muscarinic facilitation of GABA release in substantia gelatinosa of the rat spinal dorsal horn.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Atropine; Carbachol; Diamines; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Interneurons; Muscarinic Agonists; Neostigmine; Neurons; Parasympatholytics; Piperidines; Pirenzepine; Rats; Receptor, Muscarinic M1; Receptors, Muscarinic; Substantia Gelatinosa; Synaptic Transmission; Tetrodotoxin | 1998 |
Postsynaptic integration of cholinergic and dopaminergic signals on medium-sized GABAergic projection neurons in the neostriatum.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Atropine; Diamines; Electric Stimulation; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Models, Neurological; Muscarinic Agonists; Muscarinic Antagonists; Neostriatum; Neurons; Oxotremorine; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptors, Dopamine; Receptors, Muscarinic; Signal Transduction; Sulpiride; Tetrodotoxin | 1998 |
Acetylcholine acts on M3 muscarinic receptors and induces the translocation of aquaporin5 water channel via cytosolic Ca2+ elevation in rat parotid glands.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Animals; Aquaporin 5; Aquaporins; Atropine; Calcimycin; Calcium; Calcium Channel Blockers; Cytosol; Diamines; Enzyme Inhibitors; Gallic Acid; Ion Channels; Ionophores; Male; Membrane Proteins; Parasympatholytics; Parotid Gland; Rats; Rats, Wistar; Receptor, Muscarinic M3; Receptors, Muscarinic; Staurosporine | 1998 |
Presynaptic muscarinic M1 and M2 receptor modulation of auriculotemporal nerve transmission in the rat.
Topics: Acetylcholine; Animals; Atropine; Diamines; Ear; Electric Stimulation; Male; Muscarinic Antagonists; Parasympathetic Nervous System; Parasympatholytics; Parotid Gland; Pirenzepine; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Regional Blood Flow; Scalp; Synaptic Transmission | 1998 |
Pressor and bradycardic effects of tacrine and other acetylcholinesterase inhibitors in the rat.
Topics: Adrenergic Antagonists; Animals; Antidiuretic Hormone Receptor Antagonists; Atropine; Atropine Derivatives; Blood Pressure; Carbamates; Cardiovascular Agents; Chlorisondamine; Cholinergic Antagonists; Cholinesterase Inhibitors; Diamines; Diastole; Dose-Response Relationship, Drug; Heart Rate; Male; Phenylcarbamates; Physostigmine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Rivastigmine; Systole; Tacrine | 1998 |
Subtypes of muscarinic receptors regulating gallbladder cholinergic contractions.
Topics: Acetylcholine; Animals; Atropine; Diamines; Electric Stimulation; Gallbladder; Guinea Pigs; Hexamethonium; Muscarinic Antagonists; Muscle Contraction; Parasympatholytics; Piperidines; Pirenzepine; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Tetrodotoxin; Tropicamide | 1999 |
Antigen-induced hyperreactivity to histamine: role of the vagus nerves and eosinophils.
Topics: Animals; Antibodies; Antigens; Atropine; Blood Proteins; Bronchoconstriction; Diamines; Eosinophil Granule Proteins; Eosinophils; Guinea Pigs; Histamine; Integrin alpha4beta1; Integrins; Muscarinic Agonists; Muscarinic Antagonists; Ovalbumin; Receptor, Muscarinic M2; Receptors, Lymphocyte Homing; Receptors, Muscarinic; Ribonucleases; Vagotomy; Vagus Nerve | 1999 |
Presynaptic muscarinic (M3) receptors reduce excitatory transmission in dopamine neurons of the rat mesencephalon.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Atropine; Carbachol; Diamines; Dicyclomine; Dopamine; Electric Stimulation; Excitatory Postsynaptic Potentials; Mesencephalon; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Neurons; Parasympatholytics; Physostigmine; Piperidines; Pirenzepine; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reaction Time; Receptor, Muscarinic M3; Receptors, Muscarinic; Synaptic Transmission; Tetrodotoxin | 1999 |
Muscarinic cholinoceptor subtypes mediating tracheal smooth muscle contraction and inositol phosphate generation in guinea pig and rat.
Topics: Animals; Atropine; Diamines; Guinea Pigs; In Vitro Techniques; Inositol Phosphates; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Trachea | 1999 |
Characterization of the central muscarinic cholinoceptors involved in the cholinergic pressor response in anesthetized dogs.
Topics: Acetylcholine; Anesthesia; Animals; Atropine; Blood Pressure; Diamines; Dogs; Dose-Response Relationship, Drug; Male; Muscarinic Antagonists; Norepinephrine; Receptor, Muscarinic M1; Receptors, Muscarinic; Vasodilator Agents; Vasopressins | 1999 |
Selective restoration of calcium coupling to muscarinic M(3) receptors in contractile cultured airway myocytes.
Topics: Acetylcholine; Animals; Atropine; Blood Proteins; Blotting, Western; Bradykinin; Calcium; Calcium Channels; Cells, Cultured; Diamines; Dogs; Dose-Response Relationship, Drug; Fluorescent Dyes; Fura-2; Inositol 1,4,5-Trisphosphate Receptors; Macrocyclic Compounds; Muscarinic Antagonists; Muscle, Smooth; Oxazoles; Parasympatholytics; Phenotype; Piperidines; Pirenzepine; Receptor, Muscarinic M3; Receptors, Bradykinin; Receptors, Cytoplasmic and Nuclear; Receptors, Muscarinic; Trachea; Vasodilator Agents | 2000 |
Arecoline excites rat locus coeruleus neurons by activating the M2-muscarinic receptor.
Topics: Alzheimer Disease; Animals; Arecoline; Atropine; Cholinergic Agonists; Diamines; Hexamethonium; Locus Coeruleus; Male; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptors, Muscarinic | 2000 |
Functional characterization of rat submaxillary gland muscarinic receptors using microphysiometry.
Topics: Alkaloids; Animals; Atropine; Benzhydryl Compounds; Benzodiazepinones; Binding, Competitive; Biosensing Techniques; Carbachol; Cholinergic Agonists; Cresols; Diamines; Dose-Response Relationship, Drug; Furans; Male; Mandelic Acids; Muscarinic Antagonists; Naphthalenes; Phenethylamines; Phenylpropanolamine; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Submandibular Gland; Tolterodine Tartrate | 2001 |
The antinociceptive and sedative effects of carbachol and oxycodone administered into brainstem pontine reticular formation and spinal subarachnoid space in rats.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Atropine; Behavior, Animal; Carbachol; Cholinergic Agonists; Conscious Sedation; Diamines; Injections, Spinal; Male; Microinjections; Motor Activity; Muscarinic Antagonists; Pain Threshold; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Reticular Formation; Subarachnoid Space | 2001 |
Muscarinic receptors control K+ secretion in inner ear strial marginal cells.
Topics: Adrenergic beta-Agonists; Animals; Atropine; Calcium; Carbachol; Cholinergic Agonists; Cloning, Molecular; Cyclic AMP; Diamines; Dose-Response Relationship, Drug; Gerbillinae; Isoproterenol; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Potassium; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; Stria Vascularis | 2001 |
Characterization of muscarinic acetylcholine receptors in the rat epididymis.
Topics: Animals; Atropine; Cell Membrane; Diamines; Epididymis; Male; Muscarinic Antagonists; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tritium | 2001 |
Muscarinic receptor subtypes mediating vasorelaxation of the perforating branch of the human internal mammary artery.
Topics: Acetylcholine; Adult; Aged; Atropine; Diamines; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Humans; In Vitro Techniques; Mammary Arteries; Middle Aged; Muscarinic Antagonists; Piperidines; Pirenzepine; Receptors, Muscarinic; Vasodilation; Vasodilator Agents | 2001 |
Acetylcholine-induced contractions in the perforating branch of the human internal mammary artery: protective role of the vascular endothelium.
Topics: Acetylcholine; Atropine; Diamines; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Female; Humans; In Vitro Techniques; Indomethacin; Mammary Arteries; Middle Aged; Muscarinic Antagonists; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; Piperidines; Pirenzepine; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2002 |
Role of muscarinic receptors in the activation of the ventral subiculum and the consequences for dopamine release in the nucleus accumbens.
Topics: Animals; Atropine; Bicuculline; Bridged-Ring Compounds; Carbachol; Cholinergic Agonists; Diamines; Dopamine; Hippocampus; Male; Microdialysis; Muscarinic Agonists; Muscarinic Antagonists; Nicotine; Nucleus Accumbens; Oxotremorine; Pilocarpine; Pyridines; Rats; Receptors, Muscarinic; Spiro Compounds; Thiadiazoles; Tropanes | 2003 |
Characterization of muscarinic receptor subtypes in the rostral ventrolateral medulla and effects on morphine-induced antinociception in rats.
Topics: Analgesics, Opioid; Animals; Atropine; Diamines; Male; Mecamylamine; Medulla Oblongata; Microinjections; Morphine; Naloxone; Narcotic Antagonists; Pain Measurement; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Time Factors | 2003 |
Aging-related alterations in the contractile responses to acetylcholine, muscarinic cholinoceptors and cholinesterase activities in jejunum and colon of the male Fischer 344 rats.
Topics: Acetylcholine; Aging; Animals; Atropine; Cholinesterases; Colon; Diamines; Dose-Response Relationship, Drug; Gastrointestinal Motility; In Vitro Techniques; Intestine, Large; Jejunum; Male; Muscarinic Antagonists; Muscle, Smooth; Piperidines; Pirenzepine; Rats; Rats, Inbred F344 | 2004 |
Contractile effect of acetylcholine on isolated isthmic segment of fallopian tubes.
Topics: Acetylcholine; Adult; Aged; Atropine; Diamines; Dose-Response Relationship, Drug; Fallopian Tubes; Female; Follicular Phase; Humans; Lidocaine; Luteal Phase; Mecamylamine; Middle Aged; Muscle Contraction; Muscle, Smooth; Nifedipine; Piperidines; Pirenzepine; Postmenopause; Receptors, Muscarinic | 2004 |
Intrathecal clonidine inhibits mechanical allodynia via activation of the spinal muscarinic M1 receptor in streptozotocin-induced diabetic mice.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Analgesics; Animals; Atropine; Blood Glucose; Clonidine; Diabetes Mellitus, Experimental; Diamines; Injections, Spinal; Male; Mice; Motor Activity; Muscarinic Agonists; Muscarinic Antagonists; Pain; Pain Threshold; Piperidines; Pirenzepine; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Spinal Cord; Streptozocin; Stress, Mechanical; Time Factors | 2004 |
Effects of AF-DX116 and other muscarinic receptor antagonists on orthostatic hypotension in autonomic imbalanced (SART-stressed) rats.
Topics: Animals; Atropine; Atropine Derivatives; Blood Pressure; Cold Temperature; Diamines; Heart Rate; Hypotension, Orthostatic; Male; Muscarinic Antagonists; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Stress, Physiological | 2005 |
Expression and localization of muscarinic acetylcholine receptor subtypes in rat efferent ductules and epididymis.
Topics: Animals; Atropine; Carbachol; Cell Membrane; Diamines; Ejaculatory Ducts; Epididymis; Immunohistochemistry; In Vitro Techniques; Male; Muscarinic Antagonists; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic | 2006 |
Pharmacological characterization of muscarinic receptor subtypes mediating vasoconstriction of human umbilical vein.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Atropine; Diamines; Humans; In Vitro Techniques; Piperidines; Pirenzepine; Receptors, Muscarinic; Umbilical Veins; Vasoconstriction | 2006 |
Functional expression of M3, a muscarinic acetylcholine receptor subtype, in taste bud cells of mouse fungiform papillae.
Topics: Acetylcholine; Animals; Atropine; Calcium Signaling; Cells, Cultured; Diamines; Electrophysiology; Gene Expression; Inositol 1,4,5-Trisphosphate Receptors; Mice; Mice, Inbred Strains; Muscarinic Antagonists; Patch-Clamp Techniques; Phospholipase C beta; Piperidines; Pirenzepine; Receptor, Muscarinic M3; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; Synaptosomal-Associated Protein 25; Taste Buds; Tropicamide; Vesicular Acetylcholine Transport Proteins | 2008 |
Bronchodilatory effects of S-isopetasin, an antimuscarinic sesquiterpene of Petasites formosanus, on obstructive airway hyperresponsiveness.
Topics: Acetylcholine; Animals; Atropine; Binding, Competitive; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Bronchodilator Agents; Cells, Cultured; Cholinesterase Inhibitors; Diamines; Dose-Response Relationship, Drug; Guinea Pigs; Humans; Ipratropium; Male; Muscarinic Antagonists; Muscle, Smooth; N-Methylscopolamine; Neostigmine; Petasites; Piperidines; Protein Binding; Receptor, Muscarinic M3; Sesquiterpenes; Time Factors; Trachea | 2008 |
Muscarinic receptors involved in airway vascular leakage induced by experimental gastro-oesophageal reflux.
Topics: Animals; Atropine; Capillary Permeability; Diamines; Female; Ganglionic Blockers; Gastroesophageal Reflux; Guinea Pigs; Hexamethonium; In Vitro Techniques; Male; Muscarinic Antagonists; Nicotinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M4; Receptors, Muscarinic; Receptors, Nicotinic; Regional Blood Flow; Respiratory System | 2008 |
Functional characterization of the muscarinic receptors involved in endothelium-dependent relaxation in isolated canine uterine artery.
Topics: Acetylcholine; Animals; Arteries; Atropine; Cholinergic Agents; Diamines; Dogs; Endothelium, Vascular; Female; Hysterectomy; In Vitro Techniques; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Uterus | 2009 |
Spinal cholinergic mechanism of the relieving effects of electroacupuncture on cold and warm allodynia in a rat model of neuropathic pain.
Topics: Animals; Atropine; Cholinergic Agents; Cholinergic Fibers; Cold Temperature; Diamines; Disease Models, Animal; Electroacupuncture; Hot Temperature; Hyperesthesia; Male; Mecamylamine; Neuralgia; Pain Threshold; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Spinal Nerves | 2009 |
Distinct muscarinic acetylcholine receptor subtypes contribute to stability and growth, but not compensatory plasticity, of neuromuscular synapses.
Topics: Animals; Atropine; Denervation; Diamines; Female; Growth Cones; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Neurons; Muscarinic Antagonists; Muscle Fibers, Skeletal; Muscle, Skeletal; Nerve Regeneration; Neuromuscular Junction; Neuronal Plasticity; Paralysis; Presynaptic Terminals; Protein Isoforms; Receptors, Muscarinic; Wallerian Degeneration | 2009 |
The interaction between tropomyosin-related kinase B receptors and presynaptic muscarinic receptors modulates transmitter release in adult rodent motor nerve terminals.
Topics: Acetylcholine; Animals; Atropine; Brain-Derived Neurotrophic Factor; Bungarotoxins; Carbazoles; Diamines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Indole Alkaloids; Male; Mice; Motor Neurons; Muscarinic Antagonists; Nerve Growth Factors; Neuromuscular Junction; Neurotransmitter Agents; Pirenzepine; Qa-SNARE Proteins; Receptor, Nerve Growth Factor; Receptor, trkB; Receptors, Muscarinic | 2010 |
Urothelial/lamina propria spontaneous activity and the role of M3 muscarinic receptors in mediating rate responses to stretch and carbachol.
Topics: Animals; Atropine; Benzhydryl Compounds; Benzofurans; Carbachol; Cresols; Diamines; Mandelic Acids; Mucous Membrane; Muscarinic Antagonists; Muscle Contraction; Phenylpropanolamine; Piperidines; Pirenzepine; Pyrrolidines; Quinuclidines; Receptor, Muscarinic M3; Solifenacin Succinate; Stress, Mechanical; Swine; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder; Urothelium | 2011 |
Role of M2 and M3 muscarinic acetylcholine receptor subtypes in activation of bladder afferent pathways in spinal cord injured rats.
Topics: Afferent Pathways; Animals; Atropine; Benzofurans; Diamines; Female; Mucous Membrane; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Oxotremorine; Parasympatholytics; Pressure; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptor, Muscarinic M3; RNA, Messenger; Spinal Cord Injuries; Thoracic Vertebrae; Urinary Bladder; Urinary Bladder, Overactive | 2012 |
Paradoxical neostigmine-induced TOFfade: on the role of presynaptic cholinergic and adenosine receptors.
Topics: Animals; Atropine; Cholinesterase Inhibitors; Diamines; Diaphragm; In Vitro Techniques; Male; Muscarinic Antagonists; Neostigmine; Phrenic Nerve; Pirenzepine; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Cholinergic; Receptors, Presynaptic; Receptors, Purinergic P1; Synaptic Transmission; Triazines; Triazoles | 2014 |
In vitro functional interactions of acetylcholine esterase inhibitors and muscarinic receptor antagonists in the urinary bladder of the rat.
Topics: Animals; Atropine; Cholinesterase Inhibitors; Diamines; Dose-Response Relationship, Drug; Heart Atria; In Vitro Techniques; Male; Methacholine Chloride; Muscarinic Antagonists; Muscle Contraction; Obidoxime Chloride; Physostigmine; Rats; Receptor Cross-Talk; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Urinary Bladder | 2014 |
Neuroanatomical basis for cholinergic modulation of locomotor networks by sacral relay neurons with ascending lumbar projections.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Animals, Newborn; Atropine; Cholinergic Neurons; Cholinesterase Inhibitors; Diamines; Edrophonium; Electric Stimulation; Locomotion; Lumbosacral Region; Muscarinic Antagonists; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Spinal Cord | 2014 |
Expression and function of muscarinic subtype receptors in bladder interstitial cells of cajal in rats.
Topics: Action Potentials; Animals; Atropine; Calcium Channels; Carbachol; Cholinergic Agonists; Diamines; Interstitial Cells of Cajal; Male; Muscarinic Antagonists; Patch-Clamp Techniques; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Urinary Bladder | 2014 |
Cholinergic regulation of proliferation of the urothelium in response to E. coli lipopolysaccharide exposition.
Topics: Animals; Apoptosis; Atropine; Caspase 3; Cell Line; Cell Proliferation; Cholinergic Agents; Diamines; Escherichia coli; Female; Humans; Immunity, Innate; Lipopolysaccharides; Pirenzepine; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Receptors, Muscarinic; Toll-Like Receptor 4; Urothelium | 2018 |
Balanced modulation of neuromuscular synaptic transmission via M1 and M2 muscarinic receptors during inhibition of cholinesterases.
Topics: Animals; Antidotes; Atropine; Cholinesterase Inhibitors; Cholinesterases; Diamines; Diaphragm; Disease Models, Animal; Mice; Muscarinic Antagonists; Muscle Contraction; Muscle Weakness; Paraoxon; Parasympatholytics; Pirenzepine; Protective Agents; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Signal Transduction; Synaptic Transmission; Treatment Outcome | 2022 |