Page last updated: 2024-09-05

atropine and methiothepin

atropine has been researched along with methiothepin in 14 studies

Compound Research Comparison

Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010)
(atropine)
Studies
(methiothepin)
Trials
(methiothepin)
Recent Studies (post-2010) (methiothepin)
26,7111,2591,697494262

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)methiothepin (IC50)
5-hydroxytryptamine receptor 7Homo sapiens (human)0.0075
5-hydroxytryptamine receptor 6Homo sapiens (human)0.03

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19903 (21.43)18.7374
1990's8 (57.14)18.2507
2000's0 (0.00)29.6817
2010's3 (21.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schönbaum, E; Van Proosdij, J; Van Riezen, H1
Dhasmana, KM; Saxena, PR; Tadipatri, S; Villalón, CM; Zhu, YN1
Feniuk, W; Humphrey, PP; Perren, MJ1
Arvidsson, LE; Gradin, K; Hedner, T; Hjorth, S; Persson, B; Pettersson, A1
Briley, M; Moret, C1
Glusa, E1
Bingham, S; Gaster, L; King, BF; Rushant, B; Sanger, GJ; Smith, MI1
Kojima, S; Shimo, Y1
Cassel, JC; Jackisch, R; Jeltsch, H; Lauth, D; Neufang, B; Szabo, B1
Arruebo, MP; Murillo, MD; Plaza, MA1
Alper, RH; Bowman, M; Braun, CJ; Szabó, A1
Del Bel, EA; Dias, QM; Prado, WA; Silveira, JW1
Prado, WA; Reis, GM; Rossaneis, AC; Silveira, JW1
Prado, WA; Silva, JR; Silva, ML1

Other Studies

14 other study(ies) available for atropine and methiothepin

ArticleYear
Effects of various drugs supposed to interact with serotonin on PGO frequency changes induced by reserpine and 5-hydroxytryptophan.
    Monographs in neural sciences, 1976, Volume: 3

    Topics: 5-Hydroxytryptophan; Animals; Atropine; Cats; Drug Interactions; Electrodes, Implanted; Electroencephalography; Imipramine; Male; Methiothepin; Mianserin; Reserpine; Serotonin; Time Factors

1976
Role of 5-HT1-like receptors in the increase in intragastric pressure induced by 5-hydroxytryptamine in the rat.
    European journal of pharmacology, 1992, Mar-24, Volume: 213, Issue:2

    Topics: Animals; Atropine; Catecholamines; Female; Indoles; Ketanserin; Male; Methiothepin; Methysergide; Pressure; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Stomach; Tropisetron

1992
Vascular 5-HT1-like receptors that mediate contraction of the dog isolated saphenous vein and carotid arterial vasoconstriction in anaesthetized dogs are not of the 5-HT1A or 5-HT1D subtype.
    British journal of pharmacology, 1991, Volume: 102, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthesia; Animals; Atropine; Carotid Arteries; Dogs; Ganglionic Blockers; In Vitro Techniques; Indoles; Ketanserin; Methiothepin; Muscle, Smooth, Vascular; Pyrilamine; Receptors, Serotonin; Saphenous Vein; Spiperone; Sulfonamides; Sumatriptan; Tetrahydronaphthalenes; Vasoconstriction; Vasoconstrictor Agents

1991
Cardiovascular effects in the Sprague-Dawley rat of 8-hydroxy-2(di-N-propylamino) tetralin, a selective 5-hydroxytryptamine receptor agonist.
    The Journal of pharmacy and pharmacology, 1985, Volume: 37, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Atropine; Blood Pressure; Heart Rate; Hemodynamics; Injections, Intravenous; Injections, Intraventricular; Male; Methiothepin; Naphthalenes; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes; Time Factors

1985
Dihydroergocristine-induced stimulation of the 5-HT autoreceptor in the hypothalamus of the rat.
    Neuropharmacology, 1986, Volume: 25, Issue:2

    Topics: Animals; Atropine; Dihydroergotoxine; Electric Stimulation; Hypothalamus; In Vitro Techniques; Male; Methiothepin; Phentolamine; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Serotonin; Stimulation, Chemical; Sulpiride

1986
Desulfated hirugen (hirudin 54-65) induces endothelium-dependent relaxation of porcine pulmonary arteries.
    Thrombosis and haemostasis, 1994, Volume: 72, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Sequence; Animals; Arginine; Atropine; Bradykinin; Calcium; Captopril; Cyclic GMP; Dinoprost; Endothelium, Vascular; Hirudins; Histamine; Indomethacin; Ketanserin; Methiothepin; Molecular Sequence Data; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Peptide Fragments; Phentolamine; Pulmonary Artery; Swine; Vasodilation

1994
Antagonism by SB 204070 of 5-HT-evoked contractions in the dog stomach: an in-vivo model of 5-HT4 receptor function.
    The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:3

    Topics: 4-Aminobenzoic Acid; Animals; Atropine; Dioxanes; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Gastric Mucosa; Gastrointestinal Motility; Granisetron; Injections, Intravenous; Ketanserin; Male; Methiothepin; Methysergide; Muscle Contraction; Muscle, Smooth; para-Aminobenzoates; Piperidines; Random Allocation; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Stomach

1995
Investigation into the 5-hydroxytryptamine-induced atropine-resistant neurogenic contraction of guinea-pig proximal colon.
    British journal of pharmacology, 1996, Volume: 117, Issue:8

    Topics: 5-Methoxytryptamine; Animals; Atropine; Colon; Dipeptides; Dose-Response Relationship, Drug; Guinea Pigs; Indoles; Male; Methiothepin; Muscarinic Antagonists; Muscle Contraction; Ondansetron; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

1996
Downregulation of muscarinic- and 5-HT1B-mediated modulation of [3H]acetylcholine release in hippocampal slices of rats with fimbria-fornix lesions and intrahippocampal grafts of septal origin.
    Brain research, 1995, Dec-18, Volume: 704, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Atropine; Brain Tissue Transplantation; Choline; Choline O-Acetyltransferase; Cholinergic Fibers; Cholinesterase Inhibitors; Diffusion Chambers, Culture; Down-Regulation; Electric Stimulation; Female; Hippocampus; Hydroxyindoleacetic Acid; Mecamylamine; Methiothepin; Muscarinic Agonists; Muscarinic Antagonists; Neurons; Nicotinic Antagonists; Norepinephrine; Oxotremorine; Physostigmine; Pyridines; Pyrroles; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Receptors, Serotonin; Septal Nuclei; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tritium

1995
5-Hydroxytryptamine induces forestomach hypomotility in sheep through 5-HT4 receptors.
    Experimental physiology, 1996, Volume: 81, Issue:5

    Topics: Animals; Atropine; Female; Gastrointestinal Motility; Hexamethonium; Methiothepin; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin; Sheep; Stomach

1996
Cardiovascular effects produced by R-(+)-8-hydroxy-2-(di-n-propylamino) tetralin in the preoptic area of conscious rats.
    European journal of pharmacology, 1996, Nov-14, Volume: 315, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Atropine; Hemodynamics; Male; Methiothepin; Microinjections; Parasympatholytics; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists

1996
Serotonin receptors are involved in the spinal mediation of descending facilitation of surgical incision-induced increase of Fos-like immunoreactivity in rats.
    Molecular pain, 2010, Mar-23, Volume: 6

    Topics: Animals; Atropine; Cholinergic Antagonists; Immunohistochemistry; Ketanserin; Male; Methiothepin; Methysergide; Neurons; Norepinephrine; Pain; Pain Measurement; Pain, Postoperative; Phenoxybenzamine; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Spinal Cord

2010
μ1- and 5-HT1-dependent mechanisms in the anterior pretectal nucleus mediate the antinociceptive effects of retrosplenial cortex stimulation in rats.
    Life sciences, 2012, Jun-14, Volume: 90, Issue:23-24

    Topics: Animals; Atropine; Cerebral Cortex; Cobalt; Disease Models, Animal; Electric Stimulation Therapy; Male; Methiothepin; Naloxone; Pain Management; Pain Threshold; Rats; Rats, Wistar; Receptors, Opioid, mu; Receptors, Serotonin, 5-HT1

2012
Analgesia induced by 2- or 100-Hz electroacupuncture in the rat tail-flick test depends on the anterior pretectal nucleus.
    Life sciences, 2013, Nov-06, Volume: 93, Issue:20

    Topics: Analgesia; Animals; Atropine; Bicuculline; Electroacupuncture; GABA-A Receptor Antagonists; Male; Mesencephalon; Methiothepin; Methysergide; Muscarinic Antagonists; Naloxone; Naltrexone; Narcotic Antagonists; Pain Management; Rats; Rats, Wistar; Serotonin Antagonists; Somatostatin

2013