atropine has been researched along with methacholine chloride in 172 studies
| Studies (atropine) | Trials (atropine) | Recent Studies (post-2010) (atropine) | Studies (methacholine chloride) | Trials (methacholine chloride) | Recent Studies (post-2010) (methacholine chloride) |
|---|---|---|---|---|---|
| 26,711 | 1,259 | 1,697 | 5,443 | 835 | 824 |
| Protein | Taxonomy | atropine (IC50) | methacholine chloride (IC50) |
|---|---|---|---|
| galanin receptor type 3 | Homo sapiens (human) | 7.365 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 87 (50.58) | 18.7374 |
| 1990's | 57 (33.14) | 18.2507 |
| 2000's | 23 (13.37) | 29.6817 |
| 2010's | 5 (2.91) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Asakura, K; Kataura, A; Kojima, T; Narita, S; Shirasaki, H | 1 |
| Slavik, KJ; Szilagyi, JE | 1 |
| Bishop, MJ; Hildebrandt, J; Isner, PD; Pierson, DJ; Wu, SC | 1 |
| Baggett, HC; Simon, SA | 1 |
| Bernard, C; Chayvialle, JA; Cuber, JC; Herrmann, C | 1 |
| Bond, A; Boot, JR | 1 |
| Baroody, FM; Naclerio, RM | 1 |
| Hendriks, MG; Pfaffendorf, M; Van Zwieten, PA | 1 |
| Bloom, JW; Halonen, M; Mahesh, VK; Nunan, LM; Palmer, JD; Yamamura, HI | 1 |
| Boskabady, MH; Snashall, PD | 1 |
| Akerman, KE; Heikkilä, J; Jansson, C | 1 |
| Ino, T; Karagueuzian, HS; Mandel, WJ; McGrath, MF; Meesmann, M | 1 |
| Ikeda, K; Ishihara, H; Sasaki, H; Sasaki, T; Sato, M; Shimura, S; Takishima, T | 1 |
| Ekström, J; Månsson, B | 1 |
| Nishimura, S; Sorimachi, M; Yamagami, K | 1 |
| Baraniuk, JN; Emery, BE; Gawin, AZ; Kaliner, MA | 1 |
| Freschi, JE | 1 |
| Dillon, RS | 1 |
| Berkebile, C; Brown, ME; Kaliner, MA; Peden, DB; Raphael, GD; Wade, Y | 1 |
| Connors, JM; Hedge, GA; Huffman, LJ; Michalkiewicz, M; Pietrzyk, Z | 1 |
| Diamond, L; Küng, M | 1 |
| Ikeda, K; Sasaki, H; Sasaki, T; Shimura, S; Takishima, T; Yamauchi, K | 1 |
| Ekström, J; Tobin, G | 1 |
| Kwan, CY; Putney, JW | 1 |
| Ikeda, K; Sasaki, H; Sasaki, T; Shimura, S; Takishima, T | 2 |
| Nezu, E; Yoneyama, T; Yoshimura, K | 1 |
| Linden, J | 1 |
| Pedersen, PS | 1 |
| Ekström, J; Månsson, B; Olgart, L; Tobin, G | 1 |
| Ekström, J; Håkanson, R; Månsson, B; Tobin, G | 1 |
| Banks, SM; Baraniuk, JN; Kaliner, MA; Meredith, SD; Raphael, GD | 1 |
| Kenimer, JG; Takashima, A | 1 |
| Cheng, KK; Chiang, BN; Hou, ZY; Lin, CI; Vassalle, M | 1 |
| Kaliner, M; Raphael, G; Raphael, MH | 1 |
| Saga, K; Sato, K | 1 |
| Putney, JW; Takemura, H | 1 |
| Ashe, JH; McKenna, TM; Weinberger, NM | 1 |
| Fujimori, K; Inoue, K; Nakazawa, K; Takanaka, A | 1 |
| Briggs, BA; Gillett, MK; Snashall, PD | 1 |
| Miller, IF; Wong, LB; Yeates, DB | 1 |
| Kao, LS; Schneider, AS | 1 |
| Fuder, H; Muscholl, E; Wolf, K | 1 |
| Rinkema, LE; Silbaugh, SA; Stengel, PW | 1 |
| Britanisky, R; White, JF | 1 |
| Baier, HJ; Barker, JA; Chediak, AD; Wanner, A | 1 |
| Bognar, IT; Fuder, H; Muscholl, E; Pallas, S | 1 |
| Angeli, P; Lambrecht, G; Melchiorre, C; Moser, U; Mutschler, E; Wess, J | 1 |
| Baraniuk, JN; Druce, HM; Kaliner, MA; Raphael, GD | 1 |
| Sasaki, H; Sekizawa, K; Shimizu, Y; Takishima, T; Yanai, M | 1 |
| Olson, LG; Strohl, KP | 1 |
| Peskar, BA; Simmet, T; Weinerowski, P; Wittmann, G | 1 |
| Denjean, A; Duroux, P; Herve, P; Jian, R; Simonneau, G | 1 |
| Saga, K; Sato, F; Sato, K | 1 |
| Delaunois, L; Delaunois, M | 1 |
| Fujii, AM; Homcy, CJ; Lee, DL; Longabaugh, JP; Schwarz, KR; Vatner, DE; Vatner, SF | 1 |
| Bell, CL; Jones, CJ; Quinton, PM | 1 |
| Abdel-Latif, AA; Honkanen, RE | 1 |
| Okayama, H; Sasaki, H; Sasaki, T; Shimura, S; Takishima, T | 1 |
| Hida, W; Horio, S; Inoue, H; Lin, YN; Nogami, H; Okayama, M; Takishima, T; Yafuso, N | 1 |
| Snashall, PD | 1 |
| Sasaki, H; Sasaki, T; Shimura, S; Takishima, T | 1 |
| Cahill, JF; Fedan, JS; Franczak, MS; Kosten, CJ; Morey, PR; Weber, KC | 1 |
| Ekström, J; Malmberg, L; Oberg, S | 1 |
| Birnbaum, JE; Giles, PJ; Quatrale, RP; Vitale, GI | 1 |
| Dandona, P; Jeremy, JY; Mikhailidis, DP; Morgan, RJ | 1 |
| Collins, SM; Crankshaw, DJ | 1 |
| Smith, PA; Weight, FF | 1 |
| Coffman, JD; Cohen, RA | 1 |
| Ishii, K; Kato, R | 1 |
| Hyatt, RE; Manço, JC; Rodarte, JR | 1 |
| Ekström, J; Malmberg, L; Wallin, A | 1 |
| Ballesta, JJ; Borges, R; García, AG | 1 |
| Bai, TR; Martin, JG; Shore, SA; Wang, CG | 1 |
| Hida, W; Ishihara, T; Mue, S; Sekizawa, K; Takishima, T; Tamura, G; Yamauchi, K | 1 |
| Janssen, PA; Reyntjens, AJ; Schuurkes, JA; Van Daele, PG; Van Nueten, JM | 1 |
| Sun, B; Zhang, YY | 1 |
| Beld, AJ; Klaassen, AB; Kuijpers, W; Rodrigues de Miranda, JF | 1 |
| Breuing, EP; Kobashi, YL; Markus, RP | 1 |
| Grunstein, MM; Tanaka, DT | 1 |
| Maeno, H; Takagi, T; Takeda, M | 1 |
| Pholpramool, C; Triphrom, N | 1 |
| Brown, JC; Buchan, AM; Kwok, YN; McIntosh, CH; Pederson, RA | 1 |
| Masana, MI | 1 |
| Clark, SL; Ryall, RW | 1 |
| McKinney, JS; Putney, JW; Weiss, SJ | 2 |
| Podzuweit, T | 1 |
| Sato, F; Sato, K | 3 |
| Boushey, HA; Epstein, J; Holtzman, MJ; Nadel, JA; Sheppard, D | 2 |
| Iizuka, H | 1 |
| Aoki, T; Izumi, H | 1 |
| Chung, KF; Snashall, PD | 1 |
| Michniak-Mikolajczak, BB | 1 |
| Ekström, J; Malmberg, L | 1 |
| Bruce, EN; Cherniack, NS; Haxhiu, MA; Mitra, J; van Lunteren, E | 1 |
| Kern, EB; Malm, L; McCaffrey, TV; Wilder, WH | 1 |
| Gisolfi, CV; Sato, F; Sato, K; Wall, PT | 1 |
| Cheng, JB | 1 |
| Higuchi, M; Miyamoto, Y; Sakanashi, M; Takeo, S | 1 |
| Dial, E; Ecknauer, R; Johnson, LR; Rosenfeld, GC; Thompson, WJ | 1 |
| Marquis, VO; Ojewole, JA | 1 |
| Baroody, FM; Ford, S; Kagey-Sobotka, A; Lichtenstein, LM; Naclerio, RM | 1 |
| Bauer, MB; Gebhart, GF; Murphy, S | 1 |
| Giuliani, S; Holzer, P; Maggi, CA | 1 |
| Kumazawa, K; Mitsuma, T; Ogawa, T; Sobue, G | 1 |
| Bruning, TA; Chang, PC; Hendriks, MG; Pfaffendorf, M; van Zwieten, PA; Vermeij, P | 1 |
| Bloom, JW; Halonen, M; Lai, J; Palmer, JD; Witt-Enderby, PA; Yamamura, HI | 1 |
| Breukink, HJ; Hajer, R; Henricks, PA; Mars, MH | 1 |
| Diéguez, G; Fernández, N; García, JL; García-Villalón, AL; Gómez, B; Monge, L | 1 |
| del Castillo, J; Morales, M; Sierra, C; Smith, DS; Vidal, A | 1 |
| Bruning, TA; Chang, PC; Hendriks, MG; Kuypers, EA; van Zwieten, PA | 1 |
| Baroody, FM; Naclerio, RM; Wagenmann, M | 1 |
| Broadley, KJ; Lewis, CA | 1 |
| Baroody, FM; Driscoll, PV; Fleming, L; Moylan, B; Naclerio, RM; Shilstone, J | 1 |
| Carreño, A; Cinca, J; Domingo, A; Mont, L; Mourelle, M; Rodés, J; Soler-Soler, J | 1 |
| Göke, B; Herrmann-Rinke, C; Hörsch, D; McGregor, GP | 1 |
| Roffel, AF; ten Berge, RE; Weening, EC; Zaagsma, J | 1 |
| McCaffrey, TV; Yang, B | 1 |
| Elbon, CL; Fryer, AD; Jacoby, DB; Kim, AL; Levey, AI; Xiao, HQ | 1 |
| Lopez-Aguilar, J; Romero, PV; Zin, WA | 1 |
| Buckler, KJ; Dasso, LL; Vaughan-Jones, RD | 1 |
| McCaffrey, TV; Schlosser, RJ; Yang, B | 1 |
| Akuzawa, S; Ito, H; Miyake, A; Miyata, K; Nishida, A; Takemoto, Y; Takinami, Y; Yuki, H | 1 |
| Koss, MC | 1 |
| Anciaux, N; Art, T; Duvivier, DH; Lekeux, P; Van Erck, E; Vandenput, S; Votion, D | 1 |
| Uhlrich, DJ; Zhu, JJ | 1 |
| Hayashi, M; Kanno, T | 1 |
| Chen, JS; Tian, J; Wei, EQ; Zhang, WP | 1 |
| Adel-Kardan, S; Boskabady, MH | 1 |
| Peták, F; Sly, PD; Tulić, MK; Wale, JL | 1 |
| Fukushima, Y; Hisa, H; Kimura, T; Kuwakubo, F; Matsumoto, T; Nagayama, T; Satoh, S; Suzuki-Kusaba, M; Yoshida, M | 1 |
| Müller-Esterl, W; Nahorski, SR; Willars, GB | 1 |
| Kohno, S; Mizutani, N; Nabe, T; Sasaki, K; Takenaka, H | 1 |
| Cooper, PD; Reina, RD | 1 |
| Gonzalez, A; Ryan, RP; Sarna, SK | 1 |
| Brown, RH; Mitzner, W | 1 |
| Callen, A; Diener-West, M; Rubenstein, RC; Zeitlin, PL | 1 |
| Fushimi, T; Masuda, T; Saitoh, H; Shimura, S; Shirato, K | 1 |
| Boskabady, MH; Ramazani-Assari, M | 1 |
| Fozard, JR; Hannon, JP; Mazzoni, L; Tigani, B; Williams, I | 1 |
| Chan-Li, Y; Fryer, AD; Jacoby, DB; Kawashima, K; Kumaravel, B; Xiao, HQ; Yost, BL | 1 |
| Ishii, S; Nagase, T; Ouchi, Y; Shimizu, T; Shindou, H | 1 |
| Benoit, JN; Cohen, MV; Downey, JM; Oldenburg, O; Qin, Q; Sharma, AR | 1 |
| Botha, CJ; Gehring, R; Van Rooyen, JM; Venter, D | 1 |
| Dietz, JR; Fabri, PJ; Gower, WR; Lerner, EA; McCuen, RW; Schubert, ML | 1 |
| Bickford, ME; Li, J; Rowell, PP; Volk, KA | 1 |
| Chan, CK; Chen, D; Do, SH; Durieux, ME; Kamatchi, GL; Lynch, C; Tiwari, SN | 1 |
| BURKE, AW; BURNETT, WT; UPTON, AC | 1 |
| BRUST, AA; WILBER, JA | 1 |
| PAPPANO, AJ; VOLLE, RL | 1 |
| Dortch-Carnes, J; Fedan, JS; Johnston, RA; Kommineni, C; Millecchia, LL; Van Scott, MR | 1 |
| Cocks, TM; Moffatt, JD; Page, CP | 1 |
| Ma, S; Pennefather, JN; Story, ME | 1 |
| Ameredes, BT | 1 |
| DONEGAN, CK; MESSER, AL; ORGAIN, ES | 1 |
| Ali, S; Osborne, RH; Watson, MS | 1 |
| Chiung, YM; Kao, YY; Liu, PS | 1 |
| Sarna, SK | 1 |
| GERSTEN, JW; WAKIM, KG | 1 |
| Brown, RH; Groeben, H; Kaba, S; Mitzner, W | 1 |
| Amis, TC; Kairaitis, K; Lam, JC; Verma, M; Wheatley, JR | 1 |
| DUNN, TB; DYER, HM; KELLY, MG | 1 |
| HOKIN, LE; REHM, WS | 1 |
| Al-Sabah, S; Challiss, RA; Holdich, J; Krasel, C; Mahaut-Smith, MP; Markovic, D; Mistry, R | 1 |
| Char, JE; Chen, J; Cho, HJ; Dunn, C; Frisbee, E; Joo, NS; Milla, C; Modlin, SE; Park, IH; Thomas, EA; Tran, KV; Verma, R; Wine, JJ; Wolfe, MH | 1 |
| Killi, UK; Kuca, K; Soukup, O; Tobin, G; Winder, M; Wsol, V | 1 |
| Fujii, N; Kenny, GP; Louie, JC; McGinn, R; Meade, RD; Poirier, MP | 1 |
1 review(s) available for atropine and methacholine chloride
| Article | Year |
|---|---|
In-vivo and in-vitro responsiveness of bronchial smooth muscle.
Topics: Airway Resistance; Albuterol; Animals; Asthma; Atropine; Atropine Derivatives; Bronchi; Carbachol; Dose-Response Relationship, Drug; Histamine; Humans; In Vitro Techniques; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Serotonin; Trachea | 1986 |
13 trial(s) available for atropine and methacholine chloride
| Article | Year |
|---|---|
Response of nasal mucosa to histamine or methacholine challenge: use of a quantitative method to examine the modulatory effects of atropine and ipratropium bromide.
Topics: Atropine; Dose-Response Relationship, Drug; Filtration; Histamine; Humans; Ipratropium; Methacholine Chloride; Nasal Mucosa; Nasal Provocation Tests; Paper; Rhinitis, Allergic, Perennial | 1992 |
Role of cholinergic nervous system in healing neuropathic lesions: preliminary studies and prospective, double-blinded, placebo-controlled studies.
Topics: Atropine; Diabetic Neuropathies; Double-Blind Method; Female; Foot Ulcer; Humans; Hypertonic Solutions; Male; Methacholine Chloride; Parasympathetic Nervous System; Wound Healing | 1991 |
Adenosine-induced bronchoconstriction in human asthmatics: effects of pretreatment with indomethacin or atropine sulfate.
Topics: Adenosine; Administration, Inhalation; Administration, Oral; Adult; Asthma; Atropine; Bronchial Provocation Tests; Bronchoconstrictor Agents; Double-Blind Method; Humans; Indomethacin; Male; Methacholine Chloride | 1990 |
Intraesophageal perfusion of acid increases the bronchomotor response to methacholine and to isocapnic hyperventilation in asthmatic subjects.
Topics: Adolescent; Adult; Asthma; Atropine; Bronchi; Carbon Dioxide; Esophagus; Female; Gastroesophageal Reflux; Humans; Hydrochloric Acid; Hyperventilation; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Perfusion | 1986 |
Respiratory impedance in normal humans: effects of bronchodilatation and bronchoconstriction.
Topics: Adult; Aerosols; Airway Resistance; Atropine; Bronchi; Bronchodilator Agents; Histamine; Humans; Isoproterenol; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Plethysmography, Impedance; Respiratory Function Tests | 1987 |
Effect of route of atropine delivery on bronchospasm from cold air and methacholine.
Topics: Adult; Air; Atropine; Bronchial Spasm; Cold Temperature; Differential Threshold; Female; Humans; Male; Methacholine Chloride; Methacholine Compounds | 1983 |
Methacholine dose-response curves in normal and asthmatic man: effect of starting conductance and pharmacological antagonism.
Topics: Adult; Airway Resistance; Albuterol; Asthma; Atropine; Bronchi; Chlorpheniramine; Dose-Response Relationship, Drug; Female; Humans; Male; Methacholine Chloride; Methacholine Compounds; Plethysmography, Whole Body | 1984 |
Dose-dependent inhibition of cold air-induced bronchoconstriction by atropine.
Topics: Adult; Airway Resistance; Asthma; Atropine; Bronchi; Cold Temperature; Dose-Response Relationship, Drug; Female; Humans; Male; Methacholine Chloride; Methacholine Compounds | 1982 |
Physiologic responses and histamine release after nasal antigen challenge. Effect of atropine.
Topics: Adult; Airway Resistance; Allergens; Analysis of Variance; Atropine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Histamine; Histamine Release; Humans; Linear Models; Male; Mast Cells; Methacholine Chloride; Middle Aged; Nasal Lavage Fluid; Nasal Provocation Tests; Parasympathetic Nervous System; Poaceae; Pollen; Premedication; Rhinitis, Allergic, Seasonal; Severity of Illness Index; Sneezing; Time Factors | 1994 |
Modulatory effects of calcitonin gene-related peptide and substance P on human cholinergic sweat secretion.
Topics: Adult; Atropine; Calcitonin Gene-Related Peptide; Dose-Response Relationship, Drug; Humans; Male; Methacholine Chloride; Parasympathetic Nervous System; Substance P; Sweating | 1994 |
In vivo characterization of muscarinic receptor subtypes that mediate vasodilatation in patients with essential hypertension.
Topics: Atropine; Forearm; Humans; Hypertension; Male; Methacholine Chloride; Middle Aged; Nitroprusside; Parasympatholytics; Pirenzepine; Plethysmography; Receptors, Muscarinic; Vasodilation | 1995 |
Duration of action of intranasal atropine on methacholine-induced nasal secretions.
Topics: Administration, Intranasal; Adult; Analysis of Variance; Atropine; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Methacholine Chloride; Middle Aged; Muscarinic Agonists; Muscarinic Antagonists; Nasal Mucosa; Nasal Provocation Tests; Rhinitis, Allergic, Perennial; Time Factors | 1996 |
Exploring the mechanisms underpinning sweating: the development of a specialized ventilated capsule for use with intradermal microdialysis.
Topics: Administration, Cutaneous; Adult; Atropine; Bicycling; Dose-Response Relationship, Drug; Equipment Design; Female; Forearm; Humans; Male; Methacholine Chloride; Microdialysis; Muscarinic Agonists; Muscarinic Antagonists; Ouabain; Reproducibility of Results; Sweat; Sweat Glands; Sweating; Young Adult | 2016 |
158 other study(ies) available for atropine and methacholine chloride
| Article | Year |
|---|---|
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Study on the dye leakage response of nasal mucosa following topical, capsaicin challenge in guinea pigs.
Topics: Administration, Intranasal; Administration, Topical; Animals; Atropine; Benzenesulfonates; Capsaicin; Chromones; Coloring Agents; Diphenhydramine; Exudates and Transudates; Guinea Pigs; Histamine; Histamine Release; Injections, Subcutaneous; Lidocaine; Male; Methacholine Chloride; Nasal Mucosa; Nasal Provocation Tests; Substance P | 1992 |
Naloxone-induced bradycardia in pithed rats: evidence for an interaction with the peripheral sympathetic nervous system and alpha-2 adrenoceptors.
Topics: Animals; Atropine; Brimonidine Tartrate; Decerebrate State; Dose-Response Relationship, Drug; Heart Rate; Male; Methacholine Chloride; Naloxone; Phentolamine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Sympathetic Nervous System | 1992 |
Efficacy of anticholinergic and beta-adrenergic agonist treatment of maximal cholinergic bronchospasm in tracheally intubated rabbits.
Topics: Adrenergic beta-Agonists; Animals; Atropine; Bronchial Spasm; Intubation, Intratracheal; Lung Compliance; Methacholine Chloride; Parasympatholytics; Rabbits | 1992 |
Identification of muscarinic acetylcholine receptors in isolated canine lingual epithelia via voltage clamp measurements.
Topics: Acetylcholine; Action Potentials; Animals; Atropine; Barium; Barium Compounds; Chlorides; Cyclic AMP; Dogs; Electric Conductivity; Electrodiagnosis; Epithelium; Female; Ganglionic Blockers; Hexamethonium; Hexamethonium Compounds; Male; Methacholine Chloride; Muscarine; Nicotine; Receptors, Muscarinic; Tongue | 1992 |
Cooperative effects of bombesin, substance P and methacholine on the release of intestinal neurotensin in rats.
Topics: Animals; Atropine; Bombesin; Drug Synergism; Ileum; In Vitro Techniques; Intestinal Mucosa; Jejunum; Male; Methacholine Chloride; Neurotensin; Radioimmunoassay; Rats; Rats, Inbred Strains; Substance P; Tetrodotoxin | 1992 |
The effect of Ca2+ channel modulators on vagally induced bronchoconstriction in the guinea-pig.
Topics: Animals; Atropine; Bronchoconstriction; Calcium Channel Blockers; Capsaicin; Electric Stimulation; Guinea Pigs; Male; Methacholine Chloride; omega-Conotoxin GVIA; Peptides, Cyclic; Substance P; Vagus Nerve | 1992 |
Characterization of the muscarinic receptor subtype mediating vasodilation in the rat perfused mesenteric vascular bed preparation.
Topics: Animals; Atropine; Benzodiazepinones; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Male; Mesenteric Arteries; Mesenteric Veins; Methacholine Chloride; Parasympatholytics; Perfusion; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Vasodilation | 1992 |
A minority of muscarinic receptors mediate rabbit tracheal smooth muscle contraction.
Topics: Animals; Atropine; Female; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Myocardium; Parasympatholytics; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Rabbits; Radioligand Assay; Receptors, Muscarinic; Trachea | 1992 |
Enhanced muscarinic receptor blockade with atropine in the asthmatic tracheobronchial tree. Evidence for increased drug delivery.
Topics: Adult; Asthma; Atropine; Bronchial Hyperreactivity; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Female; Humans; Male; Methacholine Chloride; Middle Aged; Receptors, Muscarinic; Reproducibility of Results | 1992 |
Differential coupling of muscarinic receptors to Ca2+ mobilization and cyclic AMP in SH-SY5Y and IMR 32 neuroblastoma cells.
Topics: Acetylcholine; Alprostadil; Atropine; Calcium; Carbachol; Cyclic AMP; Humans; Methacholine Chloride; Muscarine; Neuroblastoma; Pertussis Toxin; Pirenzepine; Receptors, Muscarinic; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1991 |
The role of enhanced vagal activity on ischemic ventricular tachycardia: pharmacologic basis of inefficiency.
Topics: Adrenergic beta-Antagonists; Animals; Atropine; Cardiac Pacing, Artificial; Coronary Circulation; Coronary Disease; Dogs; Edrophonium; Electrocardiography; Female; Injections, Intravenous; Male; Methacholine Chloride; Myocardial Infarction; Tachycardia; Vagus Nerve | 1991 |
Neuropeptides and airway submucosal gland secretion.
Topics: Animals; Atropine; Cats; Dose-Response Relationship, Drug; Exocrine Glands; Glycoproteins; In Vitro Techniques; Methacholine Chloride; Mucous Membrane; Substance P; Trachea; Vasoactive Intestinal Peptide | 1991 |
On the non-adrenergic, non-cholinergic contribution to the parasympathetic nerve-evoked secretion of parotid saliva in the rat.
Topics: Animals; Atropine; Drug Combinations; Female; Injections, Intravenous; Methacholine Chloride; Neurotransmitter Agents; Parasympathetic Nervous System; Parotid Gland; Physostigmine; Rats; Rats, Inbred Strains; Saliva; Substance P; Vasoactive Intestinal Peptide | 1991 |
Internal Ca2+ mobilization by muscarinic stimulation increases secretion from adrenal chromaffin cells only in the presence of Ca2+ influx.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Medulla; Animals; Atropine; Calcium; Catecholamines; Cats; Cattle; Cytosol; Gallopamil; Kinetics; Methacholine Chloride; Muscarine; Nicotine; Parasympatholytics; Pilocarpine; Pirenzepine; Receptors, Muscarinic | 1991 |
Nasal glandular secretory response to cholinergic stimulation in humans and guinea pigs.
Topics: Adolescent; Adult; Albumins; Alkaline Phosphatase; Animals; Atropine; Guinea Pigs; Humans; Immunoglobulins; Male; Methacholine Chloride; Middle Aged; Nasal Mucosa; Proteins | 1991 |
The effect of subtype-selective muscarinic receptor antagonists on the cholinergic current in motoneurons of the lobster cardiac ganglion.
Topics: Acetylcholine; Animals; Atropine; Binding, Competitive; Ganglia; In Vitro Techniques; Mammals; Methacholine Chloride; Motor Neurons; Nephropidae; Parasympathomimetics; Piperidines; Pirenzepine; Receptors, Muscarinic | 1991 |
Human nasal glandular secretion of novel antioxidant activity: cholinergic control.
Topics: Ascorbic Acid; Atropine; Cholinergic Fibers; Enzyme-Linked Immunosorbent Assay; Exocrine Glands; Glutathione; Horseradish Peroxidase; Humans; Hydrogen Peroxide; Lactoferrin; Luminescent Measurements; Methacholine Chloride; Nasal Mucosa; Nasal Provocation Tests; Oxygen; Phenylenediamines; Reflex; Sulfhydryl Compounds | 1991 |
Muscarinic modulation of the vasodilatory effects of vasoactive intestinal peptide at the rat thyroid gland.
Topics: Acetylcholine; Animals; Atropine; Blood Flow Velocity; Male; Methacholine Chloride; Muscarinic Antagonists; Nicotine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine; Vasoactive Intestinal Peptide; Vasodilation | 1991 |
Direct inhibitory action of glucocorticoid on glycoconjugate secretion from airway submucosal glands.
Topics: Animals; Atropine; Bucladesine; Cats; Dexamethasone; Fenoterol; Glycoconjugates; In Vitro Techniques; Methacholine Chloride; Methacholine Compounds; Mucus; Phenylephrine; Trachea | 1990 |
Protein secretion in salivary glands of cats in vivo and in vitro in response to vasoactive intestinal peptide.
Topics: Animals; Atropine; Cats; Dose-Response Relationship, Drug; Female; Male; Methacholine Chloride; Parotid Gland; Proteins; Saliva; Salivary Glands; Submandibular Gland; Vasoactive Intestinal Peptide | 1990 |
Uptake and intracellular sequestration of divalent cations in resting and methacholine-stimulated mouse lacrimal acinar cells. Dissociation by Sr2+ and Ba2+ of agonist-stimulated divalent cation entry from the refilling of the agonist-sensitive intracellu
Topics: Animals; Atropine; Benzofurans; Cations, Divalent; Cytosol; Fluorescent Dyes; Fura-2; Lacrimal Apparatus; Methacholine Chloride; Methacholine Compounds; Mice; Spectrometry, Fluorescence | 1990 |
Sodium efflux from isolated submucosal gland in feline trachea.
Topics: Animals; Atropine; Cats; Electric Stimulation; Female; In Vitro Techniques; Isoproterenol; Kinetics; Male; Methacholine Chloride; Methacholine Compounds; Mucous Membrane; Muscle, Smooth; Ouabain; Perfusion; Phentolamine; Phenylephrine; Propranolol; Sodium; Tetrodotoxin; Trachea | 1990 |
Augmentation of isoproterenol-stimulated tissue cyclic AMP level by cholinergic agonists in rat parotid gland.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Atropine; Calcimycin; Calcium; Carbachol; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Isoproterenol; Male; Methacholine Chloride; Methacholine Compounds; Norepinephrine; Oxotremorine; Parotid Gland; Phentolamine; Pilocarpine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains | 1985 |
Enhanced cAMP accumulation after termination of cholinergic action in the heart.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Atropine; Cells, Cultured; Chick Embryo; Colforsin; Cyclic AMP; Heart; Isoproterenol; Methacholine Chloride; Methacholine Compounds; Myocardial Contraction; Myocardium; Parasympathomimetics; Pindolol; Receptors, Muscarinic | 1987 |
Cellular mechanism of cholinergic action in epithelial cell cultures derived from the human reabsorptive sweat duct.
Topics: Adult; Atropine; Calcimycin; Calcium; Cells, Cultured; Chlorides; Epithelium; Female; Humans; Ion Channels; Male; Methacholine Chloride; Methacholine Compounds; Sweat Glands | 1987 |
Non-adrenergic, non-cholinergic salivary secretion in the ferret.
Topics: Animals; Atropine; Carnivora; Drug Interactions; Electric Stimulation; Female; Ferrets; Male; Methacholine Chloride; Methacholine Compounds; Neurokinin A; Neuropeptides; Saliva; Salivary Glands; Substance P; Tachykinins; Vasoactive Intestinal Peptide | 1988 |
Tachykinin involvement in parasympathetic nerve-evoked salivation of the ferret.
Topics: Amylases; Animals; Atropine; Female; Ferrets; Male; Methacholine Chloride; Methacholine Compounds; Neurokinin A; Parasympathetic Nervous System; Parotid Gland; Rats; Salivary Proteins and Peptides; Salivation; Submandibular Gland; Substance P; Tachykinins | 1988 |
The pathophysiology of rhinitis. III. The control of IgG secretion.
Topics: Administration, Topical; Adolescent; Adult; Atropine; Chlorpheniramine; Female; Histamine; Humans; Immunoglobulin G; Immunohistochemistry; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Nasal Mucosa; Nasal Provocation Tests; Parasympathomimetics; Rhinitis; Staining and Labeling | 1989 |
Muscarinic-stimulated norepinephrine release and phosphoinositide hydrolysis in PC12 cells are independent events.
Topics: Adrenal Gland Neoplasms; Animals; Atropine; Cell Line; Diamines; Hydrolysis; Kinetics; Methacholine Chloride; Methacholine Compounds; Norepinephrine; Parasympathomimetics; Pheochromocytoma; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Pirenzepine; Rats; Receptors, Muscarinic | 1989 |
Role of acetylcholine in induction of repetitive activity in human atrial fibers.
Topics: Acetylcholine; Action Potentials; Adolescent; Adult; Aged; Atrial Function; Atropine; Child; Child, Preschool; Diltiazem; Drug Synergism; Epinephrine; Female; Heart; Heart Atria; Humans; In Vitro Techniques; Infant; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Theophylline | 1989 |
Gustatory rhinitis: a syndrome of food-induced rhinorrhea.
Topics: Administration, Topical; Adult; Aged; Atropine; Condiments; Female; Food Hypersensitivity; Histamine; Humans; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Nasal Mucosa; Nasal Provocation Tests; Rhinitis; Sodium Chloride; Syndrome; Therapeutic Irrigation | 1989 |
Electron probe X-ray microanalysis of cellular ions in the eccrine secretory coil cells during methacholine stimulation.
Topics: Animals; Atropine; Biological Transport; Bumetanide; Calcium; Cell Nucleus; Cytoplasm; Cytoplasmic Granules; Eccrine Glands; Electrolytes; Electron Probe Microanalysis; Macaca mulatta; Methacholine Chloride; Methacholine Compounds; Spectrum Analysis; Sweat; Sweat Glands | 1989 |
Capacitative calcium entry in parotid acinar cells.
Topics: Animals; Atropine; Benzofurans; Calcium; Cells, Cultured; Cytosol; Fluorescent Dyes; Fura-2; Methacholine Chloride; Methacholine Compounds; Parotid Gland; Rats; Receptors, Muscarinic | 1989 |
Cholinergic modulation of frequency receptive fields in auditory cortex: I. Frequency-specific effects of muscarinic agonists.
Topics: Acetylcholine; Acoustic Stimulation; Animals; Atropine; Auditory Cortex; Cats; Cholinergic Fibers; Evoked Potentials, Auditory; Male; Methacholine Chloride; Methacholine Compounds; Neurons; Parasympathomimetics | 1989 |
Existence of muscarinic suppression of a K current in PC-12 pheochromocytoma cells.
Topics: Atropine; Calcium; Electrophysiology; Methacholine Chloride; Methacholine Compounds; Parasympathomimetics; Pheochromocytoma; Potassium; Tumor Cells, Cultured | 1989 |
The influence of aerosol retention and pattern of deposition on bronchial responsiveness to atropine and methacholine in humans.
Topics: Adult; Aerosols; Airway Resistance; Asthma; Atropine; Bronchi; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Female; Forced Expiratory Volume; Humans; Lung; Male; Methacholine Chloride; Methacholine Compounds; Radionuclide Imaging; Technetium | 1989 |
Regulation of ciliary beat frequency by autonomic mechanisms: in vitro.
Topics: Animals; Atropine; Autonomic Nervous System; Cattle; Cilia; Fenoterol; Methacholine Chloride; Methacholine Compounds; Propranolol; Receptors, Adrenergic, beta; Receptors, Muscarinic; Scattering, Radiation; Trachea | 1988 |
VIP augments cholinergic-induced glycoconjugate secretion in tracheal submucosal glands.
Topics: Animals; Atropine; Cats; Drug Synergism; Exocrine Glands; Glycoconjugates; Glycoproteins; In Vitro Techniques; Methacholine Chloride; Methacholine Compounds; Mucus; Receptors, Gastrointestinal Hormone; Receptors, Vasoactive Intestinal Peptide; Trachea; Vasoactive Intestinal Peptide | 1988 |
Muscarinic receptors on bovine chromaffin cells mediate a rise in cytosolic calcium that is independent of extracellular calcium.
Topics: Acetylcholine; Adrenal Glands; Aminoquinolines; Animals; Atropine; Calcium; Cattle; Chromaffin System; Cytosol; Fluorescent Dyes; Hexamethonium; Hexamethonium Compounds; Methacholine Chloride; Methacholine Compounds; Muscarine; Receptors, Muscarinic | 1985 |
Cholinesterase activity and exposure time to acetylcholine as factors influencing the muscarinic inhibition of [3H]-noradrenaline overflow from guinea-pig isolated atria.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Atropine; Cocaine; Corticosterone; Drug Interactions; Guinea Pigs; Heart; Heart Atria; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Methacholine Chloride; Methacholine Compounds; Norepinephrine; Phentolamine; Physostigmine; Propranolol; Receptors, Muscarinic; Time Factors | 1985 |
Pulmonary aerosol actions of LY188695 (KB2413), a new potent H1-receptor antagonist.
Topics: Aerosols; Airway Obstruction; Animals; Atropine; Benzimidazoles; Bronchial Provocation Tests; Bronchodilator Agents; Chlorpheniramine; Clemastine; Guinea Pigs; Histamine; Histamine H1 Antagonists; Injections, Intravenous; Male; Methacholine Chloride; Methacholine Compounds | 1987 |
Adrenergic agents stimulate and cholinergic agents inhibit H+ secretion by amphibian jejunum.
Topics: Acetazolamide; Animals; Atropine; Benzimidazoles; Bicarbonates; Electric Conductivity; Epinephrine; Intestinal Mucosa; Isoproterenol; Jejunum; Kinetics; Methacholine Chloride; Methacholine Compounds; Norepinephrine; Omeprazole; Parasympathomimetics; Protons; Sodium; Sympathomimetics; Urodela | 1986 |
Tracheal mucosal blood flow responses to autonomic agonists.
Topics: Administration, Inhalation; Animals; Atropine; Blood Flow Velocity; Female; Isoproterenol; Methacholine Chloride; Methacholine Compounds; Methyl Ethers; Mucous Membrane; Phentolamine; Phenylephrine; Propranolol; Regional Blood Flow; Sheep; Trachea; Vasopressins | 1988 |
Muscarinic inhibition of [3H]-noradrenaline release on rabbit iris in vitro: effects of stimulation conditions on intrinsic activity of methacholine and pilocarpine.
Topics: Animals; Atropine; Electric Stimulation; Female; In Vitro Techniques; Iris; Male; Methacholine Chloride; Methacholine Compounds; Norepinephrine; Pilocarpine; Rabbits; Receptors, Muscarinic | 1988 |
Methoctramine selectively blocks cardiac muscarinic M2 receptors in vivo.
Topics: Animals; Atropine; Blood Pressure; Diamines; Heart Rate; Male; Methacholine Chloride; Methacholine Compounds; Muscarine; Myocardium; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1988 |
Pathophysiology of rhinitis. 1. Assessment of the sources of protein in methacholine-induced nasal secretions.
Topics: Adolescent; Adult; Albumins; Atropine; Humans; Immunoglobulin A; Immunoglobulin A, Secretory; Immunohistochemistry; Methacholine Chloride; Methacholine Compounds; Middle Aged; Nasal Mucosa; Proteins; Rhinitis, Allergic, Seasonal; Therapeutic Irrigation | 1988 |
Serial distribution of bronchoconstriction in normal subjects. Methacholine versus histamine.
Topics: Adult; Airway Resistance; Atropine; Bronchi; Bronchial Provocation Tests; Functional Residual Capacity; Histamine; Humans; Male; Methacholine Chloride; Methacholine Compounds; Reference Values; Respiratory Dead Space | 1988 |
Airway secretions influence upper airway patency in the rabbit.
Topics: Airway Obstruction; Animals; Atropine; Female; Male; Methacholine Chloride; Methacholine Compounds; Nasal Cavity; Pressure; Rabbits; Sodium Chloride; Trachea | 1988 |
Effect of muscarinic receptor stimulation on release of cysteinyl-leukotrienes and thromboxane B2 from anaphylactic guinea-pig hearts.
Topics: Anaphylaxis; Animals; Atropine; Guinea Pigs; Heart; Hemodynamics; Male; Methacholine Chloride; Methacholine Compounds; Myocardium; Ovalbumin; Receptors, Muscarinic; SRS-A; Thromboxane B2 | 1988 |
K+ efflux from the monkey eccrine secretory coil during the transient of stimulation with agonists.
Topics: Animals; Atropine; Bumetanide; Calcimycin; Dose-Response Relationship, Drug; Egtazic Acid; In Vitro Techniques; Macaca mulatta; Methacholine Chloride; Methacholine Compounds; Methods; Ouabain; Phenylephrine; Physostigmine; Potassium; Sweat Glands | 1988 |
Mecholyl aerosolized in the surrounding lung increases the resistance of the collateral pathways.
Topics: Administration, Inhalation; Aerosols; Airway Resistance; Animals; Atropine; Dogs; Isoproterenol; Methacholine Chloride; Methacholine Compounds; Receptors, Cholinergic | 1988 |
Impaired cardiac muscarinic receptor function in dogs with heart failure.
Topics: Adenylyl Cyclases; Animals; Atropine; Carbachol; Dogs; Female; Guanosine Triphosphate; Heart Failure; Heart Ventricles; Isoproterenol; Male; Methacholine Chloride; Methacholine Compounds; Myocardium; Oxotremorine; Receptors, Muscarinic; Sarcolemma | 1988 |
Different physiological signatures of sweat gland secretory and duct cells in culture.
Topics: Atropine; Cells, Cultured; Electrophysiology; Humans; Isoproterenol; Membrane Potentials; Methacholine Chloride; Methacholine Compounds; Microscopy, Electron; Sweat Glands | 1988 |
Characterization of cholinergic muscarinic receptors in the rabbit iris.
Topics: Animals; Atropine; Carbachol; Cerebral Cortex; Ileum; Iris; Kinetics; Methacholine Chloride; Methacholine Compounds; Microsomes; N-Methylscopolamine; Oxotremorine; Pirenzepine; Quinuclidinyl Benzilate; Rabbits; Receptors, Muscarinic; Scopolamine Derivatives | 1988 |
Neural control of contraction in isolated submucosal gland from feline trachea.
Topics: Adrenergic Fibers; Animals; Atropine; Cats; Cholinergic Fibers; Dimethylphenylpiperazinium Iodide; Electric Stimulation; Exocrine Glands; Hexamethonium Compounds; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Neostigmine; Phentolamine; Propranolol; Serotonin; Tetrodotoxin; Trachea | 1987 |
A new method of inhalation challenge with propranolol: comparison with methacholine-induced bronchoconstriction and role of vagal nerve activity.
Topics: Adolescent; Adult; Airway Resistance; Atropine; Bronchi; Bronchial Provocation Tests; Bronchial Spasm; Female; Humans; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Propranolol; Vagus Nerve | 1987 |
Contractility of isolated single submucosal gland from trachea.
Topics: Animals; Atropine; Cats; Dogs; Exocrine Glands; In Vitro Techniques; Methacholine Chloride; Methacholine Compounds; Microscopy, Electron; Mucus; Muscle Contraction; Trachea | 1986 |
Effects of a cotton bract extract on guinea pig isolated airway smooth muscle.
Topics: Adenosine; Adenosine Triphosphate; Animals; Atropine; Dialysis; Dose-Response Relationship, Drug; Electric Stimulation; Gossypium; Guinea Pigs; Histamine; In Vitro Techniques; Male; Methacholine Chloride; Methacholine Compounds; Methysergide; Muscle Contraction; Muscle, Smooth; Plant Extracts; Trachea | 1986 |
Unilateral denervation of the rat urinary bladder and reinnervation: a predominance for ipsilateral changes.
Topics: Animals; Atropine; Choline O-Acetyltransferase; Electric Stimulation; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle Denervation; Nerve Regeneration; Organ Size; Rats; Rats, Inbred Strains; Urinary Bladder | 1986 |
Electrical field stimulation of isolated primate sweat glands.
Topics: Animals; Atropine; Electric Stimulation; Female; Humans; In Vitro Techniques; Lidocaine; Macaca mulatta; Methacholine Chloride; Methacholine Compounds; Microscopy, Electron; Nerve Fibers; Physostigmine; Secretory Rate; Sweat; Sweat Glands; Synaptic Vesicles | 1986 |
Prostacyclin synthesis by the corpora cavernosa of the human penis: evidence for muscarinic control and pathological implications.
Topics: Atropine; Culture Techniques; Dose-Response Relationship, Drug; Epinephrine; Epoprostenol; Humans; Male; Methacholine Chloride; Methacholine Compounds; Parasympatholytics; Parasympathomimetics; Penile Erection; Penis | 1986 |
Dissociation of contraction and muscarinic receptor binding to isolated smooth muscle cells.
Topics: Animals; Atropine; Binding, Competitive; Carbachol; Dogs; Kinetics; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Oxotremorine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Stomach; Temperature | 1986 |
The pathway for the slow inhibitory postsynaptic potential in bullfrog sympathetic ganglia.
Topics: Acetylcholine; Action Potentials; Animals; Atropine; Cations, Divalent; Electric Stimulation; Ganglia, Sympathetic; Methacholine Chloride; Methacholine Compounds; Neural Inhibition; Parasympathomimetics; Rana catesbeiana; Receptors, Muscarinic; Tetrodotoxin | 1986 |
Cholinergic vasodilator mechanism in human fingers.
Topics: Adult; Atropine; Female; Fingers; Half-Life; Humans; Male; Methacholine Chloride; Methacholine Compounds; Microcirculation; Plethysmography; Receptors, Cholinergic; Sweating; Vascular Resistance; Vasodilation | 1987 |
Suppression by muscarinic M2 stimulation of the contractile mechanism via histamine H1 receptors in the longitudinal muscle of guinea pig ileum.
Topics: Animals; Atropine; Calcium; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histamine; Ileum; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Phentolamine; Pirenzepine; Propranolol; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Temperature; Tetrodotoxin | 1987 |
Biochemical and functional evidence for nerve sprouting in the decentralized, hypertrophied rat urinary bladder.
Topics: Animals; Atropine; Choline O-Acetyltransferase; Cholinergic Fibers; Denervation; Electric Stimulation; Ganglia, Parasympathetic; Hypertrophy; In Vitro Techniques; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Organ Size; Rats; Rats, Inbred Strains; Urinary Bladder | 1987 |
M2 muscarinoceptor-associated ionophore at the cat adrenal medulla.
Topics: Adrenal Medulla; Animals; Atropine; Binding, Competitive; Calcium; Catecholamines; Cats; Kinetics; Methacholine Chloride; Methacholine Compounds; Pirenzepine; Potassium; Quinuclidinyl Benzilate; Receptors, Muscarinic | 1987 |
Central and local cholinergic components of histamine-induced bronchoconstriction in dogs.
Topics: Animals; Atropine; Bronchial Spasm; Dogs; Dose-Response Relationship, Drug; Female; Histamine; Lung; Lung Compliance; Male; Methacholine Chloride; Methacholine Compounds; Muscle, Smooth; Reflex; Vagotomy; Vagus Nerve | 1985 |
The participation of the subepithelial airway receptor in the bronchoconstriction of monkeys.
Topics: Aerosols; Airway Resistance; Animals; Atropine; Bronchi; Constriction, Pathologic; Female; Histamine; Isoproterenol; Lidocaine; Macaca; Male; Methacholine Chloride; Methacholine Compounds; Vagus Nerve | 1985 |
Motor-stimulating properties of cisapride on isolated gastrointestinal preparations of the guinea pig.
Topics: Acetylcholine; Animals; Atropine; Cisapride; Dose-Response Relationship, Drug; Electric Stimulation; Female; Gastrointestinal Motility; Guinea Pigs; Hexamethonium Compounds; In Vitro Techniques; Intestinal Mucosa; Male; Methacholine Chloride; Methacholine Compounds; Metoclopramide; Muscle Contraction; Nicotine; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Tetrodotoxin | 1985 |
[Measurement of bronchial reactivity in asthmatics. II. Effects of atropine and metaproterenol on bronchial reactivity in asthmatics].
Topics: Adult; Airway Resistance; Asthma; Atropine; Bronchial Provocation Tests; Female; Humans; Male; Metaproterenol; Methacholine Chloride; Methacholine Compounds; Middle Aged | 1985 |
The influence of neuropharmaca on the nasal glands. Preliminary report.
Topics: Animals; Atropine; Carbachol; Methacholine Chloride; Methacholine Compounds; Nasal Mucosa; Parasympathetic Nervous System; Parasympatholytics; Parasympathomimetics; Pilocarpine; Rats; Reserpine | 1985 |
Age-related changes in the reactivity of the rat jejunum to cholinoceptor agonists.
Topics: Acetylcholine; Acetylcholinesterase; Aging; Animals; Atropine; Barium; Cholinesterases; In Vitro Techniques; Jejunum; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Parasympathomimetics; Potassium Chloride; Rats; Rats, Inbred Strains | 1985 |
Mechanisms of substance P-induced contraction of rabbit airway smooth muscle.
Topics: Animals; Atropine; Biomechanical Phenomena; Dose-Response Relationship, Drug; Ganglia, Parasympathetic; Hemicholinium 3; Hexamethonium; Hexamethonium Compounds; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Neostigmine; Nerve Block; Neural Inhibition; Rabbits; Substance P; Synaptic Transmission; Tetrodotoxin; Trachea | 1984 |
Kinetics of antisecretory action of a new H2-antagonist, YM-11170, in conscious dogs.
Topics: Animals; Atropine; Cimetidine; Dimaprit; Dogs; Famotidine; Gastric Acid; Gastric Mucosa; Histamine H2 Antagonists; Kinetics; Male; Methacholine Chloride; Methacholine Compounds; Pentagastrin; Thiazoles; Thiourea | 1983 |
Effects of cholinergic and adrenergic drugs on intraluminal pressures and contractility of the rat testis and epididymis in vivo.
Topics: Adrenergic alpha-Agonists; Animals; Atropine; Dose-Response Relationship, Drug; Epididymis; Hydrostatic Pressure; Male; Methacholine Chloride; Methacholine Compounds; Rats; Sympatholytics; Testis | 1984 |
Gastrin release from isolated perfused rat stomach after vagotomy.
Topics: Animals; Atropine; Enkephalin, Methionine; Ganglia, Parasympathetic; Gastrins; Hexamethonium; Hexamethonium Compounds; Male; Methacholine Chloride; Methacholine Compounds; Parasympathetic Nervous System; Perfusion; Propranolol; Rats; Rats, Inbred Strains; Stomach; Vagotomy | 1984 |
Lack of cholinergic modulation of tyrosine hydroxylase activation by potassium.
Topics: Animals; Atropine; Dimethylphenylpiperazinium Iodide; Enzyme Activation; Female; Guinea Pigs; Heart Atria; Hexamethonium; Hexamethonium Compounds; Male; Methacholine Chloride; Methacholine Compounds; Physostigmine; Potassium; Pteridines; Receptors, Cholinergic; Tyrosine 3-Monooxygenase | 1984 |
Inhibition by substance P of some peripheral actions of acetylcholine in the cat.
Topics: Acetylcholine; Animals; Atropine; Blood Pressure; Cats; Dimethylphenylpiperazinium Iodide; Female; Hexamethonium Compounds; In Vitro Techniques; Male; Methacholine Chloride; Methacholine Compounds; Nictitating Membrane; Substance P | 1982 |
Regulation of phosphatidate synthesis by secretagogues in parotid acinar cells.
Topics: Animals; Atropine; Calcium; Epinephrine; In Vitro Techniques; Male; Methacholine Chloride; Methacholine Compounds; Parotid Gland; Phosphatidic Acids; Phosphatidylinositols; Rats; Rats, Inbred Strains; Substance P; Time Factors | 1982 |
Receptor-mediated net breakdown of phosphatidylinositol 4,5-bisphosphate in parotid acinar cells.
Topics: Animals; Atropine; Calcium; Epinephrine; In Vitro Techniques; Male; Methacholine Chloride; Methacholine Compounds; Parotid Gland; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Propranolol; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Substance P | 1982 |
Cyclic AMP arrhythmias. Inhibition by choline esters.
Topics: Acetylcholine; Animals; Atropine; Calcium; Carbachol; Choline; Cyclic AMP; Epinephrine; Guinea Pigs; Heart Rate; Heart Ventricles; Ion Channels; Male; Methacholine Chloride; Methacholine Compounds; Muscarine; Norepinephrine; Swine | 1982 |
Cholinergic potentiation of isoproterenol-induced cAMP level in sweat gland.
Topics: Animals; Atropine; Calcimycin; Cyclic AMP; Dose-Response Relationship, Drug; Eccrine Glands; Isoproterenol; Kinetics; Macaca mulatta; Methacholine Chloride; Methacholine Compounds; Propranolol; Sweat Glands; Theophylline | 1983 |
Defective beta adrenergic response of cystic fibrosis sweat glands in vivo and in vitro.
Topics: Atropine; Child; Cystic Fibrosis; Humans; Isoproterenol; Methacholine Chloride; Methacholine Compounds; Phenylephrine; Receptors, Adrenergic, beta; Sweat; Sweat Glands; Theophylline | 1984 |
[Cardiac effects of acetylcholine and its congeners].
Topics: Acetylcholine; Animals; Atropine; Blood Pressure; Carbachol; Cardiac Output; Cardiac Pacing, Artificial; Cholinesterases; Depression, Chemical; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Heart Rate; In Vitro Techniques; Methacholine Chloride; Methacholine Compounds; Physostigmine; Vagus Nerve | 1983 |
Methacholine-stimulated release of benzoyl-arginine-ethylester esterase from mouse submandibular gland cells.
Topics: Animals; Atropine; Calcium; Carboxylic Ester Hydrolases; Castration; Culture Techniques; Dose-Response Relationship, Drug; Drug Synergism; Female; Male; Methacholine Chloride; Methacholine Compounds; Mice; Norepinephrine; Phenoxybenzamine; Submandibular Gland; Testosterone | 1984 |
Sweat production in the isolated eccrine sweat gland of the rat.
Topics: Animals; Atropine; Carbachol; Cold Temperature; Eccrine Glands; In Vitro Techniques; Male; Methacholine Chloride; Methacholine Compounds; Rats; Rats, Inbred Strains; Sweat; Sweat Glands | 1984 |
Functional evidence for sprouting or decentralized parasympathetic neurons in rat urinary bladder.
Topics: Animals; Atropine; Dihydroergotamine; Electric Stimulation; Ganglia, Parasympathetic; Ganglia, Sympathetic; Guanethidine; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle Denervation; Neurons; Parasympathetic Nervous System; Parasympathomimetics; Pelvis; Rats; Rats, Inbred Strains; Urinary Bladder | 1984 |
Hypoglossal and phrenic responses to cholinergic agents applied to ventral medullary surface.
Topics: Acetylcholine; Administration, Topical; Animals; Atropine; Carbachol; Cats; Dose-Response Relationship, Drug; Electrophysiology; Female; Hypoglossal Nerve; Injections; Male; Medulla Oblongata; Methacholine Chloride; Methacholine Compounds; Parasympathomimetics; Phrenic Nerve; Physostigmine | 1984 |
Histamine-evoked nasal secretion in the dog.
Topics: Animals; Atropine; Chlorpheniramine; Dogs; Dose-Response Relationship, Drug; Histamine; Methacholine Chloride; Methacholine Compounds; Nasal Mucosa; Nasal Provocation Tests; Stimulation, Chemical | 1983 |
In vivo and in vitro characteristics of eccrine sweating in patas and rhesus monkeys.
Topics: Animals; Atropine; Dose-Response Relationship, Drug; Eccrine Glands; Erythrocebus patas; Macaca mulatta; Male; Methacholine Chloride; Methacholine Compounds; Physical Exertion; Sweat Glands; Sweating; Temperature | 1982 |
Muscarinic cholinergic agonists at picomolar to nanomolar concentrations produce contractions of isolated rat aortae.
Topics: Animals; Aorta, Thoracic; Atropine; In Vitro Techniques; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Receptors, Muscarinic | 1982 |
Relaxant effect of trapidil on isolated dog bronchus.
Topics: Animals; Atropine; Bronchi; Bronchodilator Agents; Dogs; Female; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Pyrimidines; Tranylcypromine; Trapidil | 1982 |
Spontaneous sweat secretion in calcium-free strontium medium.
Topics: Animals; Atropine; Calcimycin; Calcium; Cell Membrane; Culture Media; Dose-Response Relationship, Drug; Lasalocid; Macaca mulatta; Methacholine Chloride; Methacholine Compounds; Ouabain; Strontium; Sweat; Sweating | 1982 |
Isolated rat gastric parietal cells: cholinergic response and pharmacology.
Topics: Acetylcholine; Aminopyrine; Animals; Atropine; Biological Transport; Carbachol; Dose-Response Relationship, Drug; Gastric Mucosa; In Vitro Techniques; Methacholine Chloride; Methacholine Compounds; Oxotremorine; Rats | 1981 |
On the responses of the isolated rectum of West African land tortoise (Kinixys spp.) to drugs.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Catecholamines; Cations; Histamine; Methacholine Chloride; Methacholine Compounds; Muscle, Smooth; Physostigmine; Rectum; Serotonin; Turtles | 1980 |
Muscarinic cholinergic stimulation of the nitric oxide-cyclic GMP signaling system in cultured rat sensory neurons.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Atropine; Capsaicin; Carbachol; Cells, Cultured; Cyclic GMP; Embryo, Mammalian; Ganglia, Spinal; Guanylate Cyclase; Methacholine Chloride; Methylene Blue; Neurons, Afferent; Nicotine; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Oxotremorine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Signal Transduction | 1994 |
Effect of omega-conotoxin on cholinergic and tachykininergic excitatory neurotransmission to the circular muscle of the guinea-pig colon.
Topics: Acetylcholine; Animals; Atropine; Calcium Channel Blockers; Colon; Dipeptides; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Indoles; Male; Methacholine Chloride; Motor Neurons; Neurokinin A; Oligopeptides; omega-Conotoxin GVIA; Peptides; Substance P; Tachykinins | 1994 |
Regulation of airway muscarinic cholinergic receptor subtypes by chronic anticholinergic treatment.
Topics: Animals; Atropine; Bronchi; Drug Administration Schedule; Female; Kinetics; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Rabbits; Receptors, Adrenergic, beta; Receptors, Muscarinic; Time Factors; Trachea; Up-Regulation | 1995 |
Effect of methacholine on mucociliary transport in bovine trachea in vitro.
Topics: Analysis of Variance; Animals; Atropine; Biological Transport; Cattle; Cilia; In Vitro Techniques; Methacholine Chloride; Movement; Mucus; Trachea | 1995 |
Cooling effects on nitric oxide production by rabbit ear and femoral arteries during cholinergic stimulation.
Topics: Animals; Arginine; Arteries; Atropine; Cold Temperature; Ear; Endothelium, Vascular; Female; Femoral Artery; In Vitro Techniques; Male; Methacholine Chloride; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Parasympathetic Nervous System; Rabbits; Regional Blood Flow; Stimulation, Chemical | 1994 |
Pharmacological sensitivity of the articular capsule of the primary spines of Eucidaris tribuloides.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Cholinesterase Inhibitors; Drug Interactions; In Vitro Techniques; Ligaments, Articular; Methacholine Chloride; Muscarine; Muscarinic Antagonists; Nicotine; Nicotinic Antagonists; Octopamine; Parasympathomimetics; Phenethylamines; Receptors, Muscarinic; Receptors, Nicotinic; Sea Urchins; Sensitivity and Specificity; Tubocurarine; Tyramine | 1993 |
In vivo characterization of vasodilating muscarinic-receptor subtypes in humans.
Topics: Acetylcholine; Adult; Atropine; Clinical Protocols; Forearm; Humans; Male; Methacholine Chloride; Pirenzepine; Receptors, Muscarinic; Vasodilation | 1994 |
Comparison of the secretory response of the nasal mucosa to methacholine and histamine.
Topics: Adult; Atropine; Diphenhydramine; Dose-Response Relationship, Drug; Female; Histamine; Humans; Kinetics; Lidocaine; Male; Methacholine Chloride; Nasal Mucosa; Receptors, Cholinergic; Receptors, Histamine H1; Reflex; Tachyphylaxis; Terfenadine | 1993 |
Airway hyper- or hyporeactivity to inhaled spasmogens 24 h after ovalbumin challenge of sensitized guinea-pigs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Administration, Inhalation; Airway Resistance; Animals; Asthma; Atropine; Bronchial Spasm; Bronchoconstrictor Agents; Bronchodilator Agents; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Male; Methacholine Chloride; Ovalbumin; Plethysmography, Whole Body; Prostaglandin Endoperoxides, Synthetic; Thromboxane A2; Vasoconstrictor Agents; Vasodilator Agents | 1995 |
Coronary denervation attenuates coronary constriction induced by muscarinic receptor stimulation in pigs.
Topics: Animals; Atropine; Coronary Circulation; Coronary Vessels; Electrocardiography; Endothelins; Female; Heart Rate; In Vitro Techniques; Male; Methacholine Chloride; Models, Biological; Muscarinic Agonists; Muscarinic Antagonists; Muscle, Smooth, Vascular; Phenols; Stimulation, Chemical; Swine; Sympathectomy, Chemical; Vasoconstriction; Ventricular Pressure | 1996 |
Galanin is a potent inhibitor of glucagon-like peptide-1 secretion from rat ileum.
Topics: Animals; Atropine; Galanin; Glucagon; Glucagon-Like Peptide 1; Ileum; Immunohistochemistry; In Vitro Techniques; Intestinal Mucosa; Kinetics; Male; Methacholine Chloride; Neurons; Peptide Fragments; Protein Precursors; Rats; Rats, Wistar | 1996 |
Differences in the prejunctional effects of methacholine and pilocarpine on the release of endogenous acetylcholine from guinea-pig trachea.
Topics: Acetylcholine; Animals; Atropine; Chromatography, High Pressure Liquid; Electric Stimulation; Guinea Pigs; Methacholine Chloride; Muscarinic Agonists; Muscarinic Antagonists; Nerve Endings; Neuromuscular Junction; Pilocarpine; Receptors, Muscarinic; Trachea; Vagus Nerve | 1996 |
The roles of muscarinic receptor subtypes in modulation of nasal ciliary action.
Topics: Atropine; Cilia; Gallamine Triethiodide; Humans; In Vitro Techniques; Methacholine Chloride; Mucociliary Clearance; Muscarinic Agonists; Muscarinic Antagonists; Nasal Mucosa; Piperidines; Pirenzepine; Receptors, Muscarinic | 1996 |
Cultures of airway parasympathetic nerves express functional M2 muscarinic receptors.
Topics: Acetylcholine; Animals; Atropine; Cells, Cultured; Electric Stimulation; Female; Gene Expression; Guinea Pigs; Immunohistochemistry; Methacholine Chloride; Muscarinic Agonists; Muscarinic Antagonists; Neurons; Parasympathetic Nervous System; Receptors, Muscarinic; RNA, Messenger; Trachea | 1996 |
Relationship between respiratory mechanics and postinspiratory muscle activity during muscarinic challenge in rabbits.
Topics: Airway Resistance; Animals; Atropine; Male; Methacholine Chloride; Rabbits; Respiratory Mechanics; Respiratory Muscles; Tidal Volume | 1996 |
Acetylcholine elevates intracellular Ca2+ via muscarinic and nicotinic receptors in rat carotid body type I cells.
Topics: Acetylcholine; Animals; Atropine; Calcium; Carotid Body; Cells, Cultured; Cholinergic Agents; Culture Media; Dimethylphenylpiperazinium Iodide; Glossopharyngeal Nerve; Intracellular Fluid; Ion Transport; Mecamylamine; Methacholine Chloride; Muscarine; Muscarinic Antagonists; Nerve Tissue Proteins; Nicotine; Nicotinic Antagonists; Oxotremorine; Rats; Receptors, Muscarinic; Receptors, Nicotinic; Receptors, Presynaptic; Signal Transduction; Species Specificity | 1996 |
Signal transduction pathways in modulation of ciliary beat frequency by methacholine.
Topics: Acetylcholine; Adenoids; Atropine; Cilia; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Methacholine Chloride; Muscarinic Agonists; Muscarinic Antagonists; Nasal Mucosa; Nitric Oxide; Parasympathomimetics; Prostaglandins; Second Messenger Systems; Signal Transduction | 1997 |
YM022, a potent and selective gastrin/CCK-B receptor antagonist, inhibits peptone meal-induced gastric acid secretion in Heidenhain pouch dogs.
Topics: Animals; Atropine; Benzodiazepines; Benzodiazepinones; Devazepide; Dogs; Dose-Response Relationship, Drug; Eating; Famotidine; Gastric Acid; Histamine; Histamine H2 Antagonists; Hormone Antagonists; Male; Methacholine Chloride; Muscarinic Antagonists; Pentagastrin; Peptones; Phenylurea Compounds; Receptors, Cholecystokinin; Sincalide; Stomach | 1997 |
Functional characterization of peripheral muscarinic subtypes in anesthetized cats.
Topics: Animals; Atropine; Blood Pressure; Cats; Gallamine Triethiodide; Galvanic Skin Response; Heart Rate; Methacholine Chloride; Muscarinic Agonists; Muscarinic Antagonists; Piperidines; Pirenzepine; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Superior Cervical Ganglion; Synaptic Transmission; Vagus Nerve; Vasodilation | 1997 |
Effect of a set stabled environmental control on pulmonary function and airway reactivity of COPD affected horses.
Topics: Animals; Atropine; Horse Diseases; Horses; Housing, Animal; Lung Compliance; Lung Diseases, Obstructive; Methacholine Chloride; Reference Values; Respiration; Respiratory Function Tests | 1998 |
Cellular mechanisms underlying two muscarinic receptor-mediated depolarizing responses in relay cells of the rat lateral geniculate nucleus.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Action Potentials; Animals; Atropine; Cations; Cesium; Geniculate Bodies; Ion Channel Gating; Ion Transport; Methacholine Chloride; Muscarinic Agonists; Muscarinic Antagonists; Nerve Tissue Proteins; Patch-Clamp Techniques; Pirenzepine; Potassium; Potassium Channels; Rats; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Tetrodotoxin | 1998 |
Photodynamic stimulation causes sustained increase in intracellular calcium concentration in cells of small cell lung carcinoma.
Topics: Antineoplastic Agents; Atropine; Calcium; Calcium Channel Blockers; Carcinoma, Small Cell; Humans; Imidazoles; Indoles; Lung Neoplasms; Methacholine Chloride; Nifedipine; Organometallic Compounds; Photochemotherapy; Photosensitizing Agents; Tumor Cells, Cultured | 1998 |
Effect of SR-140333, a neurokinin-1 receptor antagonist, on airway reactivity to methacholine in sedated rats.
Topics: Albuterol; Animals; Atropine; Female; In Vitro Techniques; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; Piperidines; Quinuclidines; Rats; Rats, Sprague-Dawley; Respiration; Trachea | 1997 |
Increased muscarinic receptor blockade by atropine in tracheal chains of ovalbumin-sensitized guinea pigs.
Topics: Animals; Asthma; Atropine; Bronchoconstrictor Agents; Dose-Response Relationship, Drug; Guinea Pigs; Male; Methacholine Chloride; Muscarinic Antagonists; Ovalbumin; Receptors, Muscarinic; Trachea | 1999 |
Muscarinic blockade of methacholine induced airway and parenchymal lung responses in anaesthetised rats.
Topics: Animals; Atropine; Bronchoconstrictor Agents; Injections, Intravenous; Lung; Lung Compliance; Male; Methacholine Chloride; Muscarinic Antagonists; Pirenzepine; Rats; Receptors, Muscarinic | 1999 |
Role of calcium channels in catecholamine secretion in the rat adrenal gland.
Topics: Acetylcholine; Adrenal Glands; Animals; Atropine; Calcium Channels, L-Type; Catecholamines; Dimethylphenylpiperazinium Iodide; Electric Stimulation; Hexamethonium; Male; Methacholine Chloride; Nifedipine; Norepinephrine; omega-Conotoxins; Rats; Rats, Wistar; Synaptic Transmission | 1999 |
Receptor phosphorylation does not mediate cross talk between muscarinic M(3) and bradykinin B(2) receptors.
Topics: Animals; Atropine; Bradykinin; Calcium; CHO Cells; Cricetinae; Gene Expression; Humans; Inositol; Inositol 1,4,5-Trisphosphate; Methacholine Chloride; Muscarinic Agonists; Muscarinic Antagonists; Phosphorylation; Receptor Cross-Talk; Receptor, Bradykinin B2; Receptor, Muscarinic M3; Receptors, Bradykinin; Receptors, Muscarinic; Recombinant Proteins; Signal Transduction; Transfection; Tritium; Type C Phospholipases | 1999 |
Nasal hyperresponsiveness to histamine induced by repetitive exposure to cedar pollen in guinea-pigs.
Topics: Administration, Inhalation; Airway Resistance; Allergens; Animals; Atropine; Disease Models, Animal; Guinea Pigs; Histamine; Immunization; Male; Methacholine Chloride; Naphazoline; Nasal Cavity; Pollen; Pyrilamine; Reference Values; Respiratory Hypersensitivity; Rhinitis, Allergic, Perennial; Sensitivity and Specificity; Trees | 1999 |
Control of salt gland activity in the hatchling green sea turtle, Chelonia mydas.
Topics: Animals; Animals, Newborn; Atrial Natriuretic Factor; Atropine; Australia; Epinephrine; Methacholine Chloride; Neuropeptide Y; Osmolar Concentration; Salt Gland; Sodium Chloride; Turtles; Vasoactive Intestinal Peptide; Vasotocin | 2000 |
Enteric locus of action of prokinetics: ABT-229, motilin, and erythromycin.
Topics: Animals; Atropine; Cell Size; Cells, Cultured; Dogs; Duodenum; Electric Stimulation; Erythromycin; Female; Gastrointestinal Agents; Gastrointestinal Motility; Hexamethonium; In Vitro Techniques; Infusions, Intra-Arterial; Intestinal Mucosa; Jejunum; Male; Methacholine Chloride; Motilin; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Rabbits; Stomach; Tetrodotoxin | 2000 |
Delayed distension of contracted airways with lung inflation in vivo.
Topics: Animals; Atropine; Bronchoconstriction; Bronchoconstrictor Agents; Bronchodilator Agents; Dogs; Lung; Methacholine Chloride; Muscle, Smooth; Respiration; Respiration, Artificial; Time Factors; Tomography, X-Ray Computed | 2000 |
A simplified cyclic adenosine monophosphate-mediated sweat rate test for quantitative measure of cystic fibrosis transmembrane regulator (CFTR) function.
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Aminophylline; Atropine; Child; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Female; Humans; Injections, Intradermal; Isoproterenol; Male; Methacholine Chloride; Muscarinic Agonists; Muscarinic Antagonists; Point Mutation; Sweat | 2000 |
Secretion and gene expression of secretory leukocyte protease inhibitor by human airway submucosal glands.
Topics: Adult; Aged; Aged, 80 and over; Atropine; Bronchi; Dexamethasone; Dose-Response Relationship, Drug; Exocrine Glands; Female; Gene Expression; Glucocorticoids; Humans; Leukocyte Elastase; Male; Methacholine Chloride; Middle Aged; Muscarinic Agonists; Muscarinic Antagonists; Piperidines; Pirenzepine; Proteinase Inhibitory Proteins, Secretory; Proteins; Respiratory Mucosa; RNA, Messenger; Secretory Leukocyte Peptidase Inhibitor; Trachea | 2001 |
Relaxant effect of Pimpinella anisum on isolated guinea pig tracheal chains and its possible mechanism(s).
Topics: Animals; Atropine; Bronchoconstrictor Agents; Bronchodilator Agents; Guinea Pigs; Male; Methacholine Chloride; Muscle Relaxation; Oils, Volatile; Plant Extracts; Trachea | 2001 |
Mechanism of airway hyperresponsiveness to adenosine induced by allergen challenge in actively sensitized Brown Norway rats.
Topics: Adenosine; Allergens; Animals; Atropine; Bradykinin; Bronchoconstriction; Bronchoconstrictor Agents; Capsaicin; Cardiovascular System; Cell Degranulation; Cromolyn Sodium; Dose-Response Relationship, Drug; Histamine; In Vitro Techniques; Ketanserin; Lung; Male; Mast Cells; Methacholine Chloride; Methysergide; Ovalbumin; p-Methoxy-N-methylphenethylamine; Rats; Rats, Inbred BN; Respiratory Hypersensitivity; Serotonin; Serotonin Antagonists; Time Factors; Vagotomy; Vasoconstrictor Agents | 2001 |
Glucocorticoid treatment increases inhibitory m(2) muscarinic receptor expression and function in the airways.
Topics: Acetylcholine; Animals; Atropine; Bronchoconstriction; Cells, Cultured; Cholinergic Agents; Cholinesterase Inhibitors; Dexamethasone; Electric Stimulation; Gallamine Triethiodide; Glucocorticoids; Guinea Pigs; Injections, Intravenous; Lung; Methacholine Chloride; Muscarinic Agonists; Muscarinic Antagonists; Neurons; Nicotinic Antagonists; Parasympathetic Nervous System; Physostigmine; Receptor, Muscarinic M2; Receptors, Muscarinic; Vagus Nerve | 2001 |
Airway hyperresponsiveness in transgenic mice overexpressing platelet activating factor receptor is mediated by an atropine-sensitive pathway.
Topics: Animals; Atropine; Bronchial Diseases; Bronchoconstrictor Agents; Bronchodilator Agents; Disease Models, Animal; Free Radical Scavengers; Methacholine Chloride; Mice; Mice, Transgenic; Muscle, Smooth; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Muscarinic; Respiratory System; Serotonin; Signal Transduction | 2002 |
Acetylcholine leads to free radical production dependent on K(ATP) channels, G(i) proteins, phosphatidylinositol 3-kinase and tyrosine kinase.
Topics: Acetylcholine; Analysis of Variance; Androstadienes; Animals; Aorta; Atropine; Cell Line; Decanoic Acids; Diazoxide; Enzyme Inhibitors; Female; Free Radical Scavengers; Genistein; GTP-Binding Protein alpha Subunits, Gi-Go; Hydroxy Acids; Ionophores; Ischemic Preconditioning; Male; Methacholine Chloride; Microscopy, Fluorescence; Muscarinic Agonists; Muscle, Smooth, Vascular; Perfusion; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Piperidines; Potassium Channel Blockers; Potassium Channels; Protein-Tyrosine Kinases; Rabbits; Rats; Reactive Oxygen Species; Receptors, Cholinergic; Signal Transduction; Tiopronin; Valinomycin; Wortmannin | 2002 |
The effect of three bufadienolide cardiac glycosides on contraction of isolated rat jejunum.
Topics: Animals; Atropine; Bufanolides; Cardiac Glycosides; Cholenes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; In Vitro Techniques; Jejunum; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Rats; Rats, Sprague-Dawley | 2002 |
Regulation of atrial natriuretic peptide secretion by cholinergic and PACAP neurons of the gastric antrum.
Topics: Animals; Atrial Natriuretic Factor; Atropine; Cholinergic Fibers; Dimethylphenylpiperazinium Iodide; Enteric Nervous System; Ganglionic Stimulants; Male; Methacholine Chloride; Muscarinic Agonists; Neurons; Neuropeptides; Neurotransmitter Agents; Parasympatholytics; Pituitary Adenylate Cyclase-Activating Polypeptide; Pyloric Antrum; Rats; Rats, Sprague-Dawley | 2003 |
Investigations of the cholinergic modulation of GABA release in rat thalamus slices.
Topics: Acetylcholine; Animals; Atropine; gamma-Aminobutyric Acid; Geniculate Bodies; Interneurons; Male; Methacholine Chloride; Muscarinic Agonists; Muscarinic Antagonists; Neural Pathways; Organ Culture Techniques; Potassium; Rats; Rats, Sprague-Dawley; Tegmentum Mesencephali; Tritium | 2003 |
Distinct regulation of expressed calcium channels 2.3 in Xenopus oocytes by direct or indirect activation of protein kinase C.
Topics: Animals; Atropine; Barium; Calcium Channels; Calcium Channels, R-Type; Carcinogens; Cation Transport Proteins; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Estrenes; Female; Gene Expression Regulation; Guanosine Diphosphate; Indoles; Maleimides; Membrane Potentials; Methacholine Chloride; Muscarinic Agonists; Muscarinic Antagonists; Oocytes; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Protein Kinase C; Pyrimidine Nucleosides; Pyrrolidinones; Receptor, Muscarinic M1; Receptors, Muscarinic; Tetradecanoylphorbol Acetate; Thionucleotides; Time Factors; Xenopus | 2003 |
Protective effect of acetyl-beta-methylcholine, carbamylcholine and atropine on x-irradiated mice.
Topics: Animals; Atropine; Carbachol; Choline; Methacholine Chloride; Mice; X-Rays | 1953 |
The circulatory and metabolic effects in man of histamine, mecholyl, tetraethylammonium and atropine in the presence of circulating epinephrine and nor-epinephrine.
Topics: Atropine; Blood Circulation; Epinephrine; Histamine; Histamine Agents; Humans; Male; Methacholine Chloride; Norepinephrine; Tetraethylammonium | 1958 |
The reversal by atropine of ganglionic blockade produced by acetylcholine or methacholine.
Topics: Acetylcholine; Atropine; Autonomic Nervous System; Ganglia; Ganglia, Autonomic; Methacholine Chloride; Methacholine Compounds | 1962 |
Hyperosmolar solution effects in guinea pig airways. IV. Lipopolysaccharide-induced alterations in airway reactivity and epithelial bioelectric responses to methacholine and hyperosmolarity.
Topics: Amiloride; Animals; Atropine; Bronchoconstrictor Agents; Diuretics; Drug Interactions; Electrophysiology; Enzyme Inhibitors; Epithelial Cells; Guinea Pigs; Indomethacin; Lipopolysaccharides; Male; Methacholine Chloride; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitroprusside; Osmolar Concentration; Perfusion; Respiratory Function Tests; Sodium Chloride; Trachea; Vasodilator Agents | 2004 |
Role of the epithelium and acetylcholine in mediating the contraction to 5-hydroxytryptamine in the mouse isolated trachea.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Atropine; Boron Compounds; Botulinum Toxins, Type A; Calcium Channel Blockers; Calcium Channels; Cartilage; Electric Stimulation; Epithelial Cells; Epithelium; Female; Ganglia, Parasympathetic; Inositol 1,4,5-Trisphosphate Receptors; Ketanserin; Methacholine Chloride; Mice; Mice, Inbred BALB C; Muscle Contraction; Muscle, Smooth; omega-Conotoxin GVIA; Receptors, Cytoplasmic and Nuclear; Serotonin; Surface-Active Agents; Tetrodotoxin; Trachea | 2004 |
Muscarinic receptors mediating contraction of female mouse urinary bladder: effects of oestrogen.
Topics: Animals; Atropine; Estrogens; Female; In Vitro Techniques; Methacholine Chloride; Mice; Mice, Inbred BALB C; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Organ Size; Pregnancy; Radioligand Assay; Receptors, Muscarinic; Urinary Bladder; Vagina | 2004 |
Cardiac activity during airway resistance alterations with intravenous and inhaled methacholine.
Topics: Acetylcholine; Administration, Inhalation; Airway Resistance; Analysis of Variance; Animals; Atropine; Bronchoconstriction; Bronchoconstrictor Agents; Bronchodilator Agents; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Electrocardiography; Heart Arrest; Heart Rate; Hydrogen-Ion Concentration; Injections, Intravenous; Male; Methacholine Chloride; Mice; Mice, Inbred C57BL; Reaction Time; Time Factors | 2004 |
The influence of vagal activity on heart block; a study of the effect of oxygen, mecholyl, and atropine on auriculoventricular conduction time.
Topics: Atropine; Heart; Heart Block; Heart Rate; Humans; Methacholine Chloride; Oxygen | 1949 |
The stimulant cathartic, emodin, contracts the rat isolated ileum by triggering release of endogenous acetylcholine.
Topics: Acetylcholine; Animals; Atropine; Catecholamines; Cathartics; Dose-Response Relationship, Drug; Emodin; Hemicholinium 3; Ileum; In Vitro Techniques; Male; Methacholine Chloride; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Neurotransmitter Uptake Inhibitors; Rats; Rats, Wistar | 2004 |
Effect of toluene diisocyanate on homeostasis of intracellular-free calcium in human neuroblastoma SH-SY5Y cells.
Topics: Atropine; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Signaling; Cell Line, Tumor; Cytosol; Dose-Response Relationship, Drug; Drug Synergism; Egtazic Acid; Endoplasmic Reticulum; Hexamethonium; Homeostasis; Humans; Intracellular Fluid; Ionomycin; Methacholine Chloride; Neuroblastoma; Potassium; Pyridines; Receptor, Muscarinic M3; Thapsigargin; Toluene 2,4-Diisocyanate; Verapamil | 2006 |
Enteric descending and afferent neural signaling stimulated by giant migrating contractions: essential contributing factors to visceral pain.
Topics: Afferent Pathways; Animals; Atropine; Calcitonin Gene-Related Peptide; Colic; Dogs; Enteric Nervous System; Female; Gastrointestinal Motility; Heart Rate; Inflammatory Bowel Diseases; Intestine, Small; Irritable Bowel Syndrome; Male; Methacholine Chloride; Muscarinic Antagonists; Muscle Contraction; Myoelectric Complex, Migrating; NG-Nitroarginine Methyl Ester; Nicotinic Agonists; Nitric Oxide Synthase; Purinergic P2 Receptor Antagonists; Receptors, Tachykinin; Serotonin Antagonists; Verapamil | 2007 |
The influence of atropine on the effect of mecholyl ion transfer on the peripheral circulation in man.
Topics: Atropine; Blood Circulation; Humans; Leadership; Methacholine Chloride | 1949 |
Different mechanisms of atelectasis formation require different treatment strategies.
Topics: Animals; Atropine; Dogs; Methacholine Chloride; Positive-Pressure Respiration; Pulmonary Atelectasis | 2008 |
Saliva production and surface tension: influences on patency of the passive upper airway.
Topics: Animals; Atropine; Humans; Male; Methacholine Chloride; Models, Animal; Pharynx; Rabbits; Respiratory Mechanics; Respiratory Physiological Phenomena; Respiratory System; Saliva; Surface Tension; Trachea | 2008 |
Effect of administration of hot water, acids, alkali, mecholyl chloride, or atropine sulfate upon the gastric mucosa of mice.
Topics: Alkalies; Animals; Atropine; Gastric Mucosa; Methacholine Chloride; Mice; Mucous Membrane; Stomach; Sulfates | 1946 |
The effect of pilocarpine, mecholyl, atropine and alcohol on the gastric potential and the secretion of hydrochloric acid.
Topics: Atropine; Ethanol; Hydrochloric Acid; Lead; Methacholine Chloride; Pilocarpine; Stomach | 1947 |
FRET-based detection of M1 muscarinic acetylcholine receptor activation by orthosteric and allosteric agonists.
Topics: Animals; Arecoline; Atropine; Binding, Competitive; Cell Membrane; Dose-Response Relationship, Drug; Fluorescence Resonance Energy Transfer; HEK293 Cells; Humans; Kinetics; Luminescent Proteins; Male; Methacholine Chloride; Mice; Microscopy, Confocal; Muscarinic Agonists; Piperidines; Receptor, Muscarinic M1; Recombinant Fusion Proteins; Transfection | 2012 |
In vivo readout of CFTR function: ratiometric measurement of CFTR-dependent secretion by individual, identifiable human sweat glands.
Topics: Adrenergic beta-Agonists; Adult; Aminophylline; Atropine; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Female; Heterozygote; Humans; Injections, Intradermal; Isoproterenol; Male; Methacholine Chloride; Muscarinic Agonists; Muscarinic Antagonists; Mutation; Purinergic P1 Receptor Antagonists; Sweat; Sweat Glands; Time Factors | 2013 |
In vitro functional interactions of acetylcholine esterase inhibitors and muscarinic receptor antagonists in the urinary bladder of the rat.
Topics: Animals; Atropine; Cholinesterase Inhibitors; Diamines; Dose-Response Relationship, Drug; Heart Atria; In Vitro Techniques; Male; Methacholine Chloride; Muscarinic Antagonists; Muscle Contraction; Obidoxime Chloride; Physostigmine; Rats; Receptor Cross-Talk; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Urinary Bladder | 2014 |