Compounds > atropine
Page last updated: 2024-09-05

atropine and mepazine

atropine has been researched along with mepazine in 5 studies

Compound Research Comparison

Studies
(atropine)		Trials
(atropine)		Recent Studies (post-2010)
(atropine)		Studies
(mepazine)		Trials
(mepazine)		Recent Studies (post-2010) (mepazine)
26,7111,2591,697121014

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)mepazine (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.495
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)1.877
Muscarinic acetylcholine receptor M2Homo sapiens (human)0.565
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.137
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.04
Alpha-2A adrenergic receptorHomo sapiens (human)1.456
Muscarinic acetylcholine receptor M1Homo sapiens (human)0.079
Alpha-2B adrenergic receptorHomo sapiens (human)0.397
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.191
Sodium-dependent noradrenaline transporter Homo sapiens (human)1.877
Alpha-1D adrenergic receptorHomo sapiens (human)0.137
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.385
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.495
Histamine H1 receptorHomo sapiens (human)0.027
D(3) dopamine receptorHomo sapiens (human)2.006
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.514
5-hydroxytryptamine receptor 6Homo sapiens (human)1.837
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.18
Mucosa-associated lymphoid tissue lymphoma translocation protein 1Homo sapiens (human)0.6933

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
BERGMANN, H1
MCCANCE, I1
CLARKE, RS; DUNDEE, JW; LOVE, WJ; MOORE, J; NICHOLL, RM1

Reviews

1 review(s) available for atropine and mepazine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

4 other study(ies) available for atropine and mepazine

ArticleYear
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
[SENSITIVITY CHANGES OF THE ISOLATED GUINEA PIG INTESTINE BY PREMEDICATION, ANESTHESIA AND SPASMOLYTICS].
    Klinische Medizin; osterreichische Zeitschrift fur wissenschaftliche und praktische Medizin, 1963, Volume: 18

    Topics: Aminopyrine; Anesthesia; Animals; Atropine; Barium; Bis-Trimethylammonium Compounds; Chlorides; Chlorpromazine; Chlorprothixene; Ether; Guinea Pigs; Intestines; Meperidine; Methantheline; Morphine; Neostigmine; Papaverine; Parasympatholytics; Pentobarbital; Phenothiazines; Promethazine; Quaternary Ammonium Compounds; Research; Scopolamine; Tubocurarine

1963
STUDIES OF POTENTIATION OF HEXOBARBITONE INFUSED INTRAVENOUSLY.
    Archives internationales de pharmacodynamie et de therapie, 1964, Mar-01, Volume: 148

    Topics: Anesthesia; Anesthesia, Intravenous; Anti-Anxiety Agents; Anticonvulsants; Atropine; Benactyzine; Carbamates; Carisoprodol; Chlorpromazine; Chlorprothixene; Hexobarbital; Hydroxyzine; Hypnotics and Sedatives; Imipramine; Infusions, Parenteral; Meprobamate; Mice; Pharmacology; Phenothiazines; Promazine; Research; Serotonin; Thalidomide; Tranquilizing Agents

1964
STUDIES OF DRUGS GIVEN BEFORE ANAESTHESIA. VI. THE PHENOTHIAZINE DERIVATIVES.
    British journal of anaesthesia, 1965, Volume: 37

    Topics: Anesthesia; Anesthesia, General; Atropine; Chlorpromazine; Chlorprothixene; Fluphenazine; Humans; Meperidine; Methohexital; Methotrimeprazine; Nitrous Oxide; Oxygen; Perphenazine; Pharmacology; Phenothiazines; Preanesthetic Medication; Prochlorperazine; Promazine; Promethazine; Thiazines; Thiethylperazine; Toxicology; Tranquilizing Agents; Trifluoperazine; Triflupromazine; Trimeprazine

1965