Compounds > atropine
Page last updated: 2024-09-05

atropine and mefenamic acid

atropine has been researched along with mefenamic acid in 7 studies

Compound Research Comparison

Studies
(atropine)		Trials
(atropine)		Recent Studies (post-2010)
(atropine)		Studies
(mefenamic acid)		Trials
(mefenamic acid)		Recent Studies (post-2010) (mefenamic acid)
26,7111,2591,6971,180158267

Protein Interaction Comparison

ProteinTaxonomyatropine (IC50)mefenamic acid (IC50)
Aldo-keto reductase family 1 member B10Homo sapiens (human)1.6
MyeloperoxidaseHomo sapiens (human)1.595
Prostaglandin G/H synthase 1Homo sapiens (human)0.116
Prostaglandin G/H synthase 2Homo sapiens (human)1.751
Aldo-keto reductase family 1 member C3Homo sapiens (human)0.56
Aldo-keto reductase family 1 member C2 Homo sapiens (human)6.97
Aldo-keto reductase family 1 member C1Homo sapiens (human)3.91

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (71.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Starr, MS; West, GB1
Collier, HO; James, GW; Schneider, C1

Reviews

1 review(s) available for atropine and mefenamic acid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

6 other study(ies) available for atropine and mefenamic acid

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
The effect of bradykinin and anti-inflammatory agents on isolated arteries.
    The Journal of pharmacy and pharmacology, 1966, Volume: 18, Issue:12

    Topics: Acetylcholine; Animals; Arteries; Atropine; Bradykinin; Drug Antagonism; Drug Synergism; Electric Stimulation; Flufenamic Acid; Guinea Pigs; Histamine; In Vitro Techniques; Kallidin; Lysergic Acid Diethylamide; Mefenamic Acid; Norepinephrine; ortho-Aminobenzoates; Phentolamine; Phenylbutazone; Rabbits; Salicylates; Serotonin; Tachyphylaxis; Vasoconstrictor Agents

1966
Antagonism by aspirin and fenamates of bronchoconstriction and nociception induced by adenosine-5'-triphosphate.
    Nature, 1966, Oct-22, Volume: 212, Issue:5060

    Topics: Acetylcholine; Adenine Nucleotides; Adenosine Triphosphate; Anaphylaxis; Animals; Anti-Inflammatory Agents; Aspirin; Atropine; Bradykinin; Bronchi; Dinitrophenols; Drug Antagonism; Ethanolamines; Flufenamic Acid; Guinea Pigs; Hexamethonium Compounds; Histamine; Histamine H1 Antagonists; Mefenamic Acid; Methysergide; Mice; ortho-Aminobenzoates; Pain; SRS-A; Tryptamines

1966